- Author:
- Mona Zhu <devnull@localhost>
- Date:
- 2011-01-12 16:56:04+13:00
- Desc:
- new 1.1 models added.
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/houart_dupont_goldbeter_1999/rawfile/2fcb46f74a8bd80672d64a051a8b9a5eef2a35d7/constitutive_law2.cellml
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This CellML file was generated on 12/2/2010 at 11:40:00 at AM using:
COR (0.9.31.1409)
Copyright 2002-2010 Dr Alan Garny
http://cor.physiol.ox.ac.uk/ - cor@physiol.ox.ac.uk
CellML 1.0 was used to generate this model
http://www.cellml.org/
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<title>Bursting, Chaos and Birhythmicity Originating from Self-modulation of the Inositol 1,4,5-triphosphate Signal in a Model for Intracellular Ca2+ Oscillations</title>
<author>
<firstname>Mona</firstname>
<surname>Zhu</surname>
<affiliation>
<shortaffil>Auckland Bioengineering Institute, University of Auckland</shortaffil>
</affiliation>
</author>
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<section id="sec_status">
<title>Model Status</title>
<para>This model has been built with the differential expressions of Houart's 1999 paper for various types of intracellular Ca2+ oscillations bassed on self-modulation of the Inositol 1,4,5-triphosphate signal. The parameter values for this model are different for different types of intracellular Ca2+ oscillations. The parameter values used for this particular model were taken from Figure 2 on page 513 and reproduces the corresponding curves. Parameter values from pages 515 and 520 may be changed to reflect curves for Bursting, Chaos, Quasiperiodicity and Birhythmicity. The initial conditions have been set after allowing the model to run for approximately 5 minutes until steady state. This file is known to run in COR and OpenCell.</para>
</section>
<sect1 id="sec_structure">
<title>Model Structure</title>
<para>
Bursting, Chaos and Birhythmicity Originating from Self-modulation of the Inositol 1,4,5-triphosphate Signal in a Model for Intracellular Ca2+ Oscillations, Houart G, Dupont G, Goldbeter A, 1999, <emphasis>Bulletin of Mathematical Biology</emphasis>
, 61, 507-530 <ulink url="http://www.ncbi.nlm.nih.gov/pubmed/17883229">PubMed ID: 17883229</ulink>
</para>
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<dc:title xmlns:dc="http://purl.org/dc/elements/1.1/">Bursting, Chaos and birhythmicity Originating from Self-modulation of the Inositol 1,4,5-triphosphate Signal in a Model for Intracellular Ca2+ Oscillations</dc:title>
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<rdf:value>This is the CellML description of the 1999 mathematical model developed by Gerald Houart, Genevieve Dupont and Albert Goldbeter for the various types of complex Ca2+ oscillations based on the mechanism of CICR.
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