- Author:
- David Nickerson <nickerso@users.sourceforge.net>
- Date:
- 2010-04-21 17:39:17+12:00
- Desc:
- adding a base experiment model which leaves only the relevant variables exposed and an instantiation of that base model into the simulations required to reproduce figure 3 from the Eskandari et al (2005) original article
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/eskandari_wright_loo_2005/rawfile/994daa333fbd2ad7017eb7b27cb8c615eb18ce20/decomposed-model/parameters_model.xml
<?xml version="1.0"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" name="parameters_model">
<component name="parameters">
<variable name="k0_12" private_interface="out" public_interface="in" units="per_M2_per_second"/>
<variable name="k0_21" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_23" private_interface="out" public_interface="in" units="per_M_per_second"/>
<variable name="k0_32" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_34" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_43" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_45" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_54" private_interface="out" public_interface="in" units="per_M_per_second"/>
<variable name="k0_25" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_52" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_56" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_65_f" private_interface="out" public_interface="in" units="per_M2_per_second"/>
<variable name="k0_61_f" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_16_f" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_65_r" private_interface="out" public_interface="in" units="per_M2_per_second"/>
<variable name="k0_61_r" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_16_r" private_interface="out" public_interface="in" units="per_second"/>
<variable name="k0_65" private_interface="out" public_interface="out" units="per_M2_per_second"/>
<variable name="k0_61" private_interface="out" public_interface="out" units="per_second"/>
<variable name="k0_16" private_interface="out" public_interface="out" units="per_second"/>
<variable name="delta" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="alpha_p" private_interface="out" public_interface="out" units="dimensionless"/>
<variable name="alpha_pp" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="N_C" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="N_Avo" private_interface="out" public_interface="in" units="per_mol"/>
<variable name="area" private_interface="out" public_interface="in" units="um2"/>
<variable name="C_T" private_interface="out" public_interface="out" units="umol"/>
<variable name="n" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="z_c" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="z_Na" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="F" private_interface="out" public_interface="in" units="C_per_mol"/>
<variable name="R" private_interface="out" public_interface="in" units="J_per_K_per_mol"/>
<variable name="T" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="V" private_interface="out" public_interface="in" units="volt"/>
<variable name="mu" private_interface="out" public_interface="out" units="dimensionless"/>
<variable name="Na_o" private_interface="out" public_interface="in" units="M"/>
<variable name="V_dot" private_interface="out" public_interface="in" units="volt_per_second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>k0_65</ci>
<piecewise>
<piece>
<ci>k0_65_r</ci>
<apply>
<lt/>
<ci>Na_o</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" type="e-notation" cellml:units="M">100 <sep/>
-3</cn>
</apply>
</piece>
<otherwise>
<ci>k0_65_f</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>k0_61</ci>
<piecewise>
<piece>
<ci>k0_61_r</ci>
<apply>
<lt/>
<ci>Na_o</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" type="e-notation" cellml:units="M">100 <sep/>
-3</cn>
</apply>
</piece>
<otherwise>
<ci>k0_61_f</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>k0_16</ci>
<piecewise>
<piece>
<ci>k0_16_r</ci>
<apply>
<lt/>
<ci>Na_o</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" type="e-notation" cellml:units="M">100 <sep/>
-3</cn>
</apply>
</piece>
<otherwise>
<ci>k0_16_f</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>alpha_p</ci>
<apply>
<minus/>
<apply>
<minus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" cellml:units="dimensionless">1</cn>
<ci>delta</ci>
</apply>
<ci>alpha_pp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>C_T</ci>
<apply>
<divide/>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" type="e-notation" cellml:units="umol_per_mol">1 <sep/>
6</cn>
<ci>N_C</ci>
</apply>
<ci>N_Avo</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>mu</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>F</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</math>
</component>
<import xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="eskandari_2005_units_model.xml">
<units name="per_second" units_ref="per_second"/>
<units name="per_second5" units_ref="per_second5"/>
<units name="volt_per_second" units_ref="volt_per_second"/>
<units name="per_mol" units_ref="per_mol"/>
<units name="umol" units_ref="umol"/>
<units name="M" units_ref="M"/>
<units name="um2" units_ref="um2"/>
<units name="mol_per_um2" units_ref="mol_per_um2"/>
<units name="mM" units_ref="mM"/>
<units name="mV" units_ref="mV"/>
<units name="J_per_K_per_mol" units_ref="J_per_K_per_mol"/>
<units name="pA_per_cm2" units_ref="pA_per_cm2"/>
<units name="uA" units_ref="uA"/>
<units name="uA_per_um2" units_ref="uA_per_um2"/>
<units name="uA_per_A" units_ref="uA_per_A"/>
<units name="umol_per_mol" units_ref="umol_per_mol"/>
<units name="C_per_mol" units_ref="C_per_mol"/>
<units name="per_M_per_second" units_ref="per_M_per_second"/>
<units name="per_M2_per_second" units_ref="per_M2_per_second"/>
<units name="M2" units_ref="M2"/>
<units name="M3" units_ref="M3"/>
<units name="M3_per_second" units_ref="M3_per_second"/>
<units name="per_M3_per_second5" units_ref="per_M3_per_second5"/>
<units name="M_per_second" units_ref="M_per_second"/>
</import>
</model>
