- Author:
- Shelley Fong <sfon036@UoA.auckland.ac.nz>
- Date:
- 2024-09-16 14:14:07+12:00
- Desc:
- Init
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/bd6/rawfile/56f23193d87b51416c7c3b155bf1047a4faa93b4/BG_NCX.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="cardiac_AP_NCX_only" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units_and_constants/units_BG.cellml">
<units name="mM" units_ref="mM"/>
<units name="fmol" units_ref="fmol"/>
<units name="per_fmol" units_ref="per_fmol"/>
<units name="J_per_mol" units_ref="J_per_mol"/>
<units name="fmol_per_sec" units_ref="fmol_per_sec"/>
<units name="C_per_mol" units_ref="C_per_mol"/>
<units name="J_per_C" units_ref="J_per_C"/>
<units name="J_per_K_per_mol" units_ref="J_per_K_per_mol"/>
<units name="fF" units_ref="fF"/>
<units name="fC" units_ref="fC"/>
<units name="fA" units_ref="fA"/>
</import>
<component name="environment">
<variable initial_value="0" name="t" public_interface="out" units="second"/>
<variable initial_value="8.314" name="R" public_interface="out" units="J_per_K_per_mol"/>
<variable initial_value="310" name="T" public_interface="out" units="kelvin"/>
<variable initial_value="96485" name="F" public_interface="out" units="C_per_mol"/>
<variable initial_value="153400" name="C_m" public_interface="out" units="fF"/>
<variable initial_value="9.3276" name="q_Ca_o" public_interface="out" units="fmol"/>
<variable initial_value="0.00456" name="q_Ca_i" public_interface="out" units="fmol"/>
<variable initial_value="725.48" name="q_Na_o" public_interface="out" units="fmol"/>
<variable initial_value="380" name="q_Na_i" public_interface="out" units="fmol"/>
<variable initial_value="0.000103509" name="q_P1_NCX" public_interface="out" units="fmol"/>
<variable initial_value="0.000103509" name="q_P2_NCX" public_interface="out" units="fmol"/>
<variable initial_value="0.000103509" name="q_P3_NCX" public_interface="out" units="fmol"/>
<variable initial_value="0.000103509" name="q_P4_NCX" public_interface="out" units="fmol"/>
<variable initial_value="0.000103509" name="q_P5_NCX" public_interface="out" units="fmol"/>
<variable initial_value="0.000103509" name="q_P6_NCX" public_interface="out" units="fmol"/>
<variable name="v_Ca_o_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Ca_i_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Na_o_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Na_i_NCX" public_interface="in" units="fmol_per_sec"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Ca_o</ci>
</apply>
<ci>v_Ca_o_NCX</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Ca_i</ci>
</apply>
<ci>v_Ca_i_NCX</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Na_o</ci>
</apply>
<ci>v_Na_o_NCX</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Na_i</ci>
</apply>
<ci>v_Na_i_NCX</ci>
</apply>
</math>
<variable initial_value="-13039" name="q_mem" public_interface="out" units="fC"/>
<variable name="I_mem_NCX" public_interface="in" units="fA"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_mem</ci>
</apply>
<ci>I_mem_NCX</ci>
</apply>
</math>
</component>
<component name="NCX_parameters">
<variable initial_value="417309" name="kappa_1_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.39522e+07" name="kappa_2_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="472.755" name="kappa_3_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.39522e+07" name="kappa_4_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="417309" name="kappa_5_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.370405" name="kappa_6_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.93394e+08" name="K_1_NCX" public_interface="out" units="per_fmol"/>
<variable initial_value="14.1045" name="K_2_NCX" public_interface="out" units="per_fmol"/>
<variable initial_value="263471" name="K_3_NCX" public_interface="out" units="per_fmol"/>
<variable initial_value="2.39875e+06" name="K_4_NCX" public_interface="out" units="per_fmol"/>
<variable initial_value="2373.73" name="K_5_NCX" public_interface="out" units="per_fmol"/>
<variable initial_value="956.214" name="K_6_NCX" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0137751" name="K_Na_i" public_interface="out" units="per_fmol"/>
<variable initial_value="10.2446" name="K_Ca_i" public_interface="out" units="per_fmol"/>
<variable initial_value="0.470129" name="K_Na_o" public_interface="out" units="per_fmol"/>
<variable initial_value="7572.91" name="K_Ca_o" public_interface="out" units="per_fmol"/>
<variable initial_value="3" name="nNa_o_NCX" public_interface="out" units="dimensionless"/>
<variable initial_value="3" name="nNa_i_NCX" public_interface="out" units="dimensionless"/>
<variable initial_value="-0.55679" name="zf_NCX" public_interface="out" units="dimensionless"/>
<variable initial_value="0.44321" name="zr_NCX" public_interface="out" units="dimensionless"/>
</component>
<component name="NCX">
<variable name="t" public_interface="in" units="second"/>
<variable name="R" public_interface="in" units="J_per_K_per_mol"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="F" public_interface="in" units="C_per_mol"/>
<variable name="C_m" public_interface="in" units="fF"/>
<variable name="K_1_NCX" public_interface="in" units="per_fmol"/>
<variable name="K_2_NCX" public_interface="in" units="per_fmol"/>
<variable name="K_3_NCX" public_interface="in" units="per_fmol"/>
<variable name="K_4_NCX" public_interface="in" units="per_fmol"/>
<variable name="K_5_NCX" public_interface="in" units="per_fmol"/>
<variable name="K_6_NCX" public_interface="in" units="per_fmol"/>
<variable name="K_Ca_o" public_interface="in" units="per_fmol"/>
<variable name="K_Ca_i" public_interface="in" units="per_fmol"/>
<variable name="K_Na_o" public_interface="in" units="per_fmol"/>
<variable name="K_Na_i" public_interface="in" units="per_fmol"/>
<variable name="kappa_1_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_2_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_3_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_4_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_5_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_6_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="nNa_o_NCX" public_interface="in" units="dimensionless"/>
<variable name="nNa_i_NCX" public_interface="in" units="dimensionless"/>
<variable name="zf_NCX" public_interface="in" units="dimensionless"/>
<variable name="zr_NCX" public_interface="in" units="dimensionless"/>
<variable name="q_Ca_o" public_interface="in" units="fmol"/>
<variable name="q_Ca_i" public_interface="in" units="fmol"/>
<variable name="q_Na_o" public_interface="in" units="fmol"/>
<variable name="q_Na_i" public_interface="in" units="fmol"/>
<variable name="q_P1_NCX" public_interface="in" units="fmol"/>
<variable name="q_P2_NCX" public_interface="in" units="fmol"/>
<variable name="q_P3_NCX" public_interface="in" units="fmol"/>
<variable name="q_P4_NCX" public_interface="in" units="fmol"/>
<variable name="q_P5_NCX" public_interface="in" units="fmol"/>
<variable name="q_P6_NCX" public_interface="in" units="fmol"/>
<variable name="q_mem" public_interface="in" units="fC"/>
<variable name="mu_Ca_o" units="J_per_mol"/>
<variable name="mu_Ca_i" units="J_per_mol"/>
<variable name="mu_Na_o" units="J_per_mol"/>
<variable name="mu_Na_i" units="J_per_mol"/>
<variable name="mu_P1_NCX" units="J_per_mol"/>
<variable name="mu_P2_NCX" units="J_per_mol"/>
<variable name="mu_P3_NCX" units="J_per_mol"/>
<variable name="mu_P4_NCX" units="J_per_mol"/>
<variable name="mu_P5_NCX" units="J_per_mol"/>
<variable name="mu_P6_NCX" units="J_per_mol"/>
<variable name="v_Ca_o_NCX" public_interface="out" units="fmol_per_sec"/>
<variable name="v_Ca_i_NCX" public_interface="out" units="fmol_per_sec"/>
<variable name="v_Na_o_NCX" public_interface="out" units="fmol_per_sec"/>
<variable name="v_Na_i_NCX" public_interface="out" units="fmol_per_sec"/>
<variable name="v_P1_NCX" units="fmol_per_sec"/>
<variable name="v_P2_NCX" units="fmol_per_sec"/>
<variable name="v_P3_NCX" units="fmol_per_sec"/>
<variable name="v_P4_NCX" units="fmol_per_sec"/>
<variable name="v_P5_NCX" units="fmol_per_sec"/>
<variable name="v_P6_NCX" units="fmol_per_sec"/>
<variable name="Af_r1" units="J_per_mol"/>
<variable name="Ar_r1" units="J_per_mol"/>
<variable name="v_r1" public_interface="out" units="fmol_per_sec"/>
<variable name="Af_r2" units="J_per_mol"/>
<variable name="Ar_r2" units="J_per_mol"/>
<variable name="v_r2" public_interface="out" units="fmol_per_sec"/>
<variable name="Af_r3" units="J_per_mol"/>
<variable name="Ar_r3" units="J_per_mol"/>
<variable name="v_r3" public_interface="out" units="fmol_per_sec"/>
<variable name="Af_r4" units="J_per_mol"/>
<variable name="Ar_r4" units="J_per_mol"/>
<variable name="v_r4" public_interface="out" units="fmol_per_sec"/>
<variable name="Af_r5" units="J_per_mol"/>
<variable name="Ar_r5" units="J_per_mol"/>
<variable name="v_r5" public_interface="out" units="fmol_per_sec"/>
<variable name="Af_r6" units="J_per_mol"/>
<variable name="Ar_r6" units="J_per_mol"/>
<variable name="v_r6" public_interface="out" units="fmol_per_sec"/>
<variable name="V_mem" units="volt"/>
<variable name="I_mem_NCX" public_interface="out" units="fA"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>V_mem</ci>
<apply>
<divide/>
<ci>q_mem</ci>
<ci>C_m</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>I_mem_NCX</ci>
<apply>
<times/>
<ci>F</ci>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<ci>zf_NCX</ci>
</apply>
<ci>v_r6</ci>
</apply>
<apply>
<times/>
<ci>zr_NCX</ci>
<ci>v_r6</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_Ca_o</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_Ca_o</ci>
<ci>q_Ca_o</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_Ca_i</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_Ca_i</ci>
<ci>q_Ca_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_Na_o</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_Na_o</ci>
<ci>q_Na_o</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_Na_i</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_Na_i</ci>
<ci>q_Na_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_P1_NCX</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_1_NCX</ci>
<ci>q_P1_NCX</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_P2_NCX</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_2_NCX</ci>
<ci>q_P2_NCX</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_P3_NCX</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_3_NCX</ci>
<ci>q_P3_NCX</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_P4_NCX</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_4_NCX</ci>
<ci>q_P4_NCX</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_P5_NCX</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_5_NCX</ci>
<ci>q_P5_NCX</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_P6_NCX</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_6_NCX</ci>
<ci>q_P6_NCX</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_r1</ci>
<apply>
<times/>
<ci>kappa_1_NCX</ci>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<ci>Af_r1</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<ci>Ar_r1</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_r2</ci>
<apply>
<times/>
<ci>kappa_2_NCX</ci>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<ci>Af_r2</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<ci>Ar_r2</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_r3</ci>
<apply>
<times/>
<ci>kappa_3_NCX</ci>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<ci>Af_r3</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<ci>Ar_r3</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_r4</ci>
<apply>
<times/>
<ci>kappa_4_NCX</ci>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<ci>Af_r4</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<ci>Ar_r4</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_r5</ci>
<apply>
<times/>
<ci>kappa_5_NCX</ci>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<ci>Af_r5</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<ci>Ar_r5</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_r6</ci>
<apply>
<times/>
<ci>kappa_6_NCX</ci>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<ci>Af_r6</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<ci>Ar_r6</ci>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Af_r1</ci>
<ci>mu_P1_NCX</ci>
</apply>
<apply>
<eq/>
<ci>Af_r2</ci>
<apply>
<plus/>
<ci>mu_P2_NCX</ci>
<ci>mu_Ca_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Af_r3</ci>
<ci>mu_P3_NCX</ci>
</apply>
<apply>
<eq/>
<ci>Af_r4</ci>
<ci>mu_P4_NCX</ci>
</apply>
<apply>
<eq/>
<ci>Af_r5</ci>
<apply>
<plus/>
<ci>mu_P5_NCX</ci>
<apply>
<times/>
<ci>nNa_o_NCX</ci>
<ci>mu_Na_o</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Af_r6</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_6_NCX</ci>
<ci>q_P6_NCX</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>zf_NCX</ci>
<ci>F</ci>
<ci>V_mem</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Ar_r1</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>nNa_i_NCX</ci>
<ci>mu_Na_i</ci>
</apply>
<ci>mu_P2_NCX</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Ar_r2</ci>
<ci>mu_P3_NCX</ci>
</apply>
<apply>
<eq/>
<ci>Ar_r3</ci>
<ci>mu_P4_NCX</ci>
</apply>
<apply>
<eq/>
<ci>Ar_r4</ci>
<apply>
<plus/>
<ci>mu_P5_NCX</ci>
<ci>mu_Ca_o</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Ar_r5</ci>
<ci>mu_P6_NCX</ci>
</apply>
<apply>
<eq/>
<ci>Ar_r6</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<ci>K_1_NCX</ci>
<ci>q_P1_NCX</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>zr_NCX</ci>
<ci>F</ci>
<ci>V_mem</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Ca_o_NCX</ci>
<ci>v_r4</ci>
</apply>
<apply>
<eq/>
<ci>v_Ca_i_NCX</ci>
<apply>
<minus/>
<ci>v_r2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Na_o_NCX</ci>
<apply>
<times/>
<apply>
<minus/>
<ci>nNa_o_NCX</ci>
</apply>
<ci>v_r5</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Na_i_NCX</ci>
<apply>
<times/>
<ci>nNa_i_NCX</ci>
<ci>v_r1</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_P1_NCX</ci>
<apply>
<minus/>
<ci>v_r6</ci>
<ci>v_r1</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_P2_NCX</ci>
<apply>
<minus/>
<ci>v_r1</ci>
<ci>v_r2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_P3_NCX</ci>
<apply>
<minus/>
<ci>v_r2</ci>
<ci>v_r3</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_P4_NCX</ci>
<apply>
<plus/>
<apply>
<minus/>
<ci>v_r4</ci>
</apply>
<ci>v_r3</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_P5_NCX</ci>
<apply>
<plus/>
<apply>
<minus/>
<ci>v_r5</ci>
</apply>
<ci>v_r4</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_P6_NCX</ci>
<apply>
<plus/>
<apply>
<minus/>
<ci>v_r6</ci>
</apply>
<ci>v_r5</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_P1_NCX</ci>
</apply>
<ci>v_P1_NCX</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_P2_NCX</ci>
</apply>
<ci>v_P2_NCX</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_P3_NCX</ci>
</apply>
<ci>v_P3_NCX</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_P4_NCX</ci>
</apply>
<ci>v_P4_NCX</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_P5_NCX</ci>
</apply>
<ci>v_P5_NCX</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_P6_NCX</ci>
</apply>
<ci>v_P6_NCX</ci>
</apply>
</math>
</component>
<connection>
<map_components component_1="NCX" component_2="NCX_parameters"/>
<map_variables variable_1="K_1_NCX" variable_2="K_1_NCX"/>
<map_variables variable_1="K_2_NCX" variable_2="K_2_NCX"/>
<map_variables variable_1="K_3_NCX" variable_2="K_3_NCX"/>
<map_variables variable_1="K_4_NCX" variable_2="K_4_NCX"/>
<map_variables variable_1="K_5_NCX" variable_2="K_5_NCX"/>
<map_variables variable_1="K_6_NCX" variable_2="K_6_NCX"/>
<map_variables variable_1="K_Ca_o" variable_2="K_Ca_o"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="kappa_1_NCX" variable_2="kappa_1_NCX"/>
<map_variables variable_1="kappa_2_NCX" variable_2="kappa_2_NCX"/>
<map_variables variable_1="kappa_3_NCX" variable_2="kappa_3_NCX"/>
<map_variables variable_1="kappa_4_NCX" variable_2="kappa_4_NCX"/>
<map_variables variable_1="kappa_5_NCX" variable_2="kappa_5_NCX"/>
<map_variables variable_1="kappa_6_NCX" variable_2="kappa_6_NCX"/>
<map_variables variable_1="nNa_o_NCX" variable_2="nNa_o_NCX"/>
<map_variables variable_1="nNa_i_NCX" variable_2="nNa_i_NCX"/>
<map_variables variable_1="zf_NCX" variable_2="zf_NCX"/>
<map_variables variable_1="zr_NCX" variable_2="zr_NCX"/>
</connection>
<connection>
<map_components component_1="NCX" component_2="environment"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_Ca_o" variable_2="q_Ca_o"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="q_P1_NCX" variable_2="q_P1_NCX"/>
<map_variables variable_1="q_P2_NCX" variable_2="q_P2_NCX"/>
<map_variables variable_1="q_P3_NCX" variable_2="q_P3_NCX"/>
<map_variables variable_1="q_P4_NCX" variable_2="q_P4_NCX"/>
<map_variables variable_1="q_P5_NCX" variable_2="q_P5_NCX"/>
<map_variables variable_1="q_P6_NCX" variable_2="q_P6_NCX"/>
<map_variables variable_1="v_Ca_o_NCX" variable_2="v_Ca_o_NCX"/>
<map_variables variable_1="v_Ca_i_NCX" variable_2="v_Ca_i_NCX"/>
<map_variables variable_1="v_Na_o_NCX" variable_2="v_Na_o_NCX"/>
<map_variables variable_1="v_Na_i_NCX" variable_2="v_Na_i_NCX"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_NCX" variable_2="I_mem_NCX"/>
</connection>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#model">
<bqs:reference xmlns:bqs="http://www.cellml.org/bqs/1.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<dc:subject xmlns:dc="http://purl.org/dc/elements/1.1/" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<bqs:subject_type xmlns:bqs="http://www.cellml.org/bqs/1.0#">keyword</bqs:subject_type>
<rdf:value xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Bag xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:li xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">protein-modules</rdf:li>
</rdf:Bag>
</rdf:value>
</dc:subject>
</bqs:reference>
</rdf:Description>
</rdf:RDF>
</model>
