Location: ECC_MSK (Rios et al. 1993) @ 4cfc10570f68 / Experiments / MWC_18_test.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2022-07-13 11:17:11+12:00
Desc:
Update simulation script; remove unrelevant files
Permanent Source URI:
https://models.physiomeproject.org/workspace/8af/rawfile/4cfc10570f68ee5a90ebd668511ee78dfff1874c/Experiments/MWC_18_test.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="MWC_18_test" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="../cellLib/Components/units.cellml">
        <units name="mV" units_ref="mV"/>
        <units name="ms" units_ref="ms"/>
        <units name="per_ms" units_ref="per_ms"/>
    </import>
    <import xlink:href="../Components/MWC_18.cellml">
        <component component_ref="MWC_18" name="MWC_18"/>
    </import>
    <import xlink:href="../Components/Para.cellml">
        <component component_ref="Para" name="Para"/>
    </import>
    <import xlink:href="../cellLib/Protocols/Patch_clamp_protocol.cellml">
        <component component_ref="dPulse_protocol_ms" name="dPulse_protocol_ms"/>
    </import>
    <import xlink:href="../cellLib/Components/time.cellml">
        <component component_ref="time_ms" name="time"/>
    </import>
    <component name="output_18">
        <variable name="P_o" public_interface="in" units="dimensionless"/>
        <variable name="Q" public_interface="in" units="dimensionless"/>
        <variable name="t" public_interface="in" units="ms"/>
        <variable name="V" public_interface="in" units="mV"/>
        <variable name="dQ" public_interface="in" units="per_ms"/>
        <variable name="C_0" public_interface="in" units="dimensionless"/>
        <variable name="C_1" public_interface="in" units="dimensionless"/>
        <variable name="C_2" public_interface="in" units="dimensionless"/>
        <variable name="C_3" public_interface="in" units="dimensionless"/>
        <variable name="C_4" public_interface="in" units="dimensionless"/>
        <variable name="C_5" public_interface="in" units="dimensionless"/>
        <variable name="C_6" public_interface="in" units="dimensionless"/>
        <variable name="C_7" public_interface="in" units="dimensionless"/>
        <variable name="C_8" public_interface="in" units="dimensionless"/>
        <variable name="O_0" public_interface="in" units="dimensionless"/>
        <variable name="O_1" public_interface="in" units="dimensionless"/>
        <variable name="O_2" public_interface="in" units="dimensionless"/>
        <variable name="O_3" public_interface="in" units="dimensionless"/>
        <variable name="O_4" public_interface="in" units="dimensionless"/>
        <variable name="O_5" public_interface="in" units="dimensionless"/>
        <variable name="O_6" public_interface="in" units="dimensionless"/>
        <variable name="O_7" public_interface="in" units="dimensionless"/>
        <variable name="O_8" public_interface="in" units="dimensionless"/>
    </component>
    <component name="clamp_para">
        <variable initial_value="100" name="t_ss" public_interface="out" units="ms"/>
        <variable initial_value="-80" name="V_actHolding" public_interface="out" units="mV"/>
        <variable initial_value="100" name="t_act" public_interface="out" units="ms"/>
        <variable initial_value="-40" name="V_actTest" public_interface="out" units="mV"/>
        <variable initial_value="10" name="t_cd" public_interface="out" units="ms"/>
        <variable initial_value="100" name="T_cd" public_interface="out" units="ms"/>
        <variable initial_value="20" name="V_cd" public_interface="out" units="mV"/>
    </component>
    <component name="free_para_18">
        <variable initial_value="7" name="K" public_interface="out" units="mV"/>
        <variable initial_value="0.001" name="k_L" public_interface="out" units="per_ms"/>
        <variable initial_value="1500" name="k_Lminus" public_interface="out" units="per_ms"/>
        <variable initial_value="0.3" name="f" public_interface="out" units="dimensionless"/>
        <variable initial_value="-10" name="V0" public_interface="out" units="mV"/>
        <variable initial_value="0.850266862" name="C0_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="0.139226833" name="C1_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="0.009973985" name="C2_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="0.000408297" name="C3_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="1.04E-05" name="C4_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="1.71E-07" name="C5_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="1.75E-09" name="C6_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="1.02E-11" name="C7_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="2.62E-14" name="C8_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="1.89E-06" name="O0_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="1.01E-05" name="O1_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="2.36E-05" name="O2_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="3.16E-05" name="O3_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="2.64E-05" name="O4_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="1.41E-05" name="O5_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="4.72E-06" name="O6_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="9.00E-07" name="O7_init" public_interface="out" units="dimensionless"/>
        <variable initial_value="7.52E-08" name="O8_init" public_interface="out" units="dimensionless"/>
    </component>
    <connection>
        <map_components component_1="MWC_18" component_2="output_18"/>
        <map_variables variable_1="C_0" variable_2="C_0"/>
        <map_variables variable_1="C_1" variable_2="C_1"/>
        <map_variables variable_1="C_2" variable_2="C_2"/>
        <map_variables variable_1="C_3" variable_2="C_3"/>
        <map_variables variable_1="C_4" variable_2="C_4"/>
        <map_variables variable_1="C_5" variable_2="C_5"/>
        <map_variables variable_1="C_6" variable_2="C_6"/>
        <map_variables variable_1="C_7" variable_2="C_7"/>
        <map_variables variable_1="C_8" variable_2="C_8"/>
        <map_variables variable_1="O_0" variable_2="O_0"/>
        <map_variables variable_1="O_1" variable_2="O_1"/>
        <map_variables variable_1="O_2" variable_2="O_2"/>
        <map_variables variable_1="O_3" variable_2="O_3"/>
        <map_variables variable_1="O_4" variable_2="O_4"/>
        <map_variables variable_1="O_5" variable_2="O_5"/>
        <map_variables variable_1="O_6" variable_2="O_6"/>
        <map_variables variable_1="O_7" variable_2="O_7"/>
        <map_variables variable_1="O_8" variable_2="O_8"/>
        <map_variables variable_1="P_o" variable_2="P_o"/>
        <map_variables variable_1="Q" variable_2="Q"/>
        <map_variables variable_1="dQ" variable_2="dQ"/>
    </connection>
    <connection>
        <map_components component_1="MWC_18" component_2="free_para_18"/>
        <map_variables variable_1="C0_init" variable_2="C0_init"/>
        <map_variables variable_1="C1_init" variable_2="C1_init"/>
        <map_variables variable_1="C2_init" variable_2="C2_init"/>
        <map_variables variable_1="C3_init" variable_2="C3_init"/>
        <map_variables variable_1="C4_init" variable_2="C4_init"/>
        <map_variables variable_1="C5_init" variable_2="C5_init"/>
        <map_variables variable_1="C6_init" variable_2="C6_init"/>
        <map_variables variable_1="C7_init" variable_2="C7_init"/>
        <map_variables variable_1="C8_init" variable_2="C8_init"/>
        <map_variables variable_1="O0_init" variable_2="O0_init"/>
        <map_variables variable_1="O1_init" variable_2="O1_init"/>
        <map_variables variable_1="O2_init" variable_2="O2_init"/>
        <map_variables variable_1="O3_init" variable_2="O3_init"/>
        <map_variables variable_1="O4_init" variable_2="O4_init"/>
        <map_variables variable_1="O5_init" variable_2="O5_init"/>
        <map_variables variable_1="O6_init" variable_2="O6_init"/>
        <map_variables variable_1="O7_init" variable_2="O7_init"/>
        <map_variables variable_1="O8_init" variable_2="O8_init"/>
        <map_variables variable_1="K" variable_2="K"/>
        <map_variables variable_1="k_L" variable_2="k_L"/>
        <map_variables variable_1="k_Lminus" variable_2="k_Lminus"/>
        <map_variables variable_1="f" variable_2="f"/>
        <map_variables variable_1="V0" variable_2="V0"/>
    </connection>
    <connection>
        <map_components component_1="MWC_18" component_2="Para"/>
        <map_variables variable_1="alpha" variable_2="alpha"/>
        <map_variables variable_1="C1_i" variable_2="C1_i"/>
        <map_variables variable_1="C2_i" variable_2="C2_i"/>
        <map_variables variable_1="C3_i" variable_2="C3_i"/>
        <map_variables variable_1="C4_i" variable_2="C4_i"/>
        <map_variables variable_1="C5_i" variable_2="C5_i"/>
        <map_variables variable_1="C6_i" variable_2="C6_i"/>
        <map_variables variable_1="C7_i" variable_2="C7_i"/>
        <map_variables variable_1="O1_i" variable_2="O1_i"/>
        <map_variables variable_1="O2_i" variable_2="O2_i"/>
        <map_variables variable_1="O3_i" variable_2="O3_i"/>
        <map_variables variable_1="O4_i" variable_2="O4_i"/>
        <map_variables variable_1="O5_i" variable_2="O5_i"/>
        <map_variables variable_1="O6_i" variable_2="O6_i"/>
        <map_variables variable_1="O7_i" variable_2="O7_i"/>
    </connection>
    <connection>
        <map_components component_1="MWC_18" component_2="dPulse_protocol_ms"/>
        <map_variables variable_1="V" variable_2="V"/>
    </connection>
    <connection>
        <map_components component_1="MWC_18" component_2="time"/>
        <map_variables variable_1="t" variable_2="time"/>
    </connection>
    <connection>
        <map_components component_1="output_18" component_2="dPulse_protocol_ms"/>
        <map_variables variable_1="V" variable_2="V"/>
    </connection>
    <connection>
        <map_components component_1="output_18" component_2="time"/>
        <map_variables variable_1="t" variable_2="time"/>
    </connection>
    <connection>
        <map_components component_1="clamp_para" component_2="dPulse_protocol_ms"/>
        <map_variables variable_1="t_ss" variable_2="t_ss"/>
        <map_variables variable_1="V_actHolding" variable_2="V_actHolding"/>
        <map_variables variable_1="t_act" variable_2="t_act"/>
        <map_variables variable_1="V_actTest" variable_2="V_actTest"/>
        <map_variables variable_1="t_cd" variable_2="t_cd"/>
        <map_variables variable_1="T_cd" variable_2="T_cd"/>
        <map_variables variable_1="V_cd" variable_2="V_cd"/>
    </connection>
    <connection>
        <map_components component_1="dPulse_protocol_ms" component_2="time"/>
        <map_variables variable_1="time" variable_2="time"/>
    </connection>
</model>