- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2022-07-13 14:40:08+12:00
- Desc:
- Add doc
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/8af/rawfile/25fefc9d5db1b1e3b70d4f69b0b493968f5924cb/Doc/MWC_10_experiment.rst
MWC-10 model experiment
---------------------------------
In the `MWC_10_experiment <Experiments/MWC_10_test.cellml/view>`_, the `MWC-10 model <../Components/MWC_10.cellml>`_ is configured and parameterised with an applied `voltage clamp protocol <../cellLib/Protocols/dPulse_protocol_ms.cellml>`_.
You can change the parameters of stimulation in the component ``clamp_para``. You can also bypass the parameters in the components ``free_para_10`` and ``Para``, and define your own parameters.
Steady states
----------------
Figure [#]_ shows the voltage dependencies and transfer function.
.. [#]
.. figure:: ../Simulation/simFig4.png
:width: 75%
:align: center
:alt: simFig4
Kinetic transients
-------------------
Figure [#]_ shows charge movement transients in reference simulation with different test voltages.
.. [#]
.. figure:: ../Simulation/simFig9_r.png
:width: 75%
:align: center
:alt: simFig9_r
Figure [#]_ shows charge movement transients in perchlorate simulation with different test voltages.
.. [#]
.. figure:: ../Simulation/simFig9_p.png
:width: 75%
:align: center
:alt: simFig9_p
Figure [#]_ shows the open probability and charge movement current when 908 parameters are used.
.. [#]
.. figure:: ../Simulation/simFig11.png
:width: 75%
:align: center
:alt: simFig11
Figure [#]_ shows the open probability and charge movement current when 827 parameters are used.
.. [#]
.. figure:: ../Simulation/simFig11_1.png
:width: 75%
:align: center
:alt: simFig11_1
