- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2022-07-01 10:53:47+12:00
- Desc:
- First version of the model and original data
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/8af/rawfile/20e3e451c78771d3f0cb8f5244f0ca68d84b4139/Components/buildsrc/MWC_10.txt
def model MWC_10 as
def import using "../cellLib/Components/units.cellml" for
unit mV using unit mV;
unit ms using unit ms;
unit per_ms using unit per_ms;
enddef;
def import using "C0_S2.cellml" for
comp C0 using comp C0_S2;
enddef;
def import using "C_S3.cellml" for
comp C1 using comp C_S3;
enddef;
def import using "C_S3.cellml" for
comp C2 using comp C_S3;
enddef;
def import using "C_S3.cellml" for
comp C3 using comp C_S3;
enddef;
def import using "CN_S2.cellml" for
comp C4 using comp CN_S2;
enddef;
def import using "O0_S2.cellml" for
comp O0 using comp O0_S2;
enddef;
def import using "O_S3.cellml" for
comp O1 using comp O_S3;
enddef;
def import using "O_S3.cellml" for
comp O2 using comp O_S3;
enddef;
def import using "O_S3.cellml" for
comp O3 using comp O_S3;
enddef;
def import using "ON_S2.cellml" for
comp O4 using comp ON_S2;
enddef;
def comp MWC_10 as
var alpha: per_ms {pub: in};
var C0_init: dimensionless {pub: in, priv: out};
var C1_init: dimensionless {pub: in, priv: out};
var C2_init: dimensionless {pub: in, priv: out};
var C3_init: dimensionless {pub: in, priv: out};
var C4_init: dimensionless {pub: in, priv: out};
var O0_init: dimensionless {pub: in, priv: out};
var O1_init: dimensionless {pub: in, priv: out};
var O2_init: dimensionless {pub: in, priv: out};
var O3_init: dimensionless {pub: in, priv: out};
var O4_init: dimensionless {pub: in, priv: out};
var N: dimensionless {init: 4, pub: out, priv: out};
var C1_i: dimensionless {pub: in, priv: out};
var C2_i: dimensionless {pub: in, priv: out};
var C3_i: dimensionless {pub: in, priv: out};
var O1_i: dimensionless {pub: in, priv: out};
var O2_i: dimensionless {pub: in, priv: out};
var O3_i: dimensionless {pub: in, priv: out};
var K: mV {pub: in};
var k_L: per_ms {pub: in, priv: out};
var k_Lminus: per_ms {pub: in, priv: out};
var f: dimensionless {pub: in, priv: out};
var V0: mV {pub: in};
var k_C: per_ms {pub: out, priv: out};
var k_Cminus: per_ms {pub: out, priv: out};
var V: mV {pub: in};
var C_0: dimensionless {pub: out, priv: in};
var C_1: dimensionless {pub: out, priv: in};
var C_2: dimensionless {pub: out, priv: in};
var C_3: dimensionless {pub: out, priv: in};
var C_4: dimensionless {pub: out, priv: in};
var O_0: dimensionless {pub: out, priv: in};
var O_1: dimensionless {pub: out, priv: in};
var O_2: dimensionless {pub: out, priv: in};
var O_3: dimensionless {pub: out, priv: in};
var O_4: dimensionless {pub: out, priv: in};
var dC_1: per_ms {pub: out, priv: in};
var dC_2: per_ms {pub: out, priv: in};
var dC_3: per_ms {pub: out, priv: in};
var dC_4: per_ms {pub: out, priv: in};
var dO_1: per_ms {pub: out, priv: in};
var dO_2: per_ms {pub: out, priv: in};
var dO_3: per_ms {pub: out, priv: in};
var dO_4: per_ms {pub: out, priv: in};
var O: dimensionless ;
var C: dimensionless ;
var norm: dimensionless {pub: out, priv: out};
var P_o: dimensionless {pub: out};
var Q: dimensionless {pub: out};
var dQ: per_ms {pub: out};
var t: ms {pub: in, priv: out};
k_C = 0.5{dimensionless}*alpha*exp((V-V0)/(8{dimensionless}*K));
k_Cminus = 0.5{dimensionless}*alpha*exp(-(V-V0)/(8{dimensionless}*K));
O = O_0+O_1+O_2+O_3+O_4;
C = C_0+C_1+C_2+C_3+C_4;
norm = C+O;
P_o = O/norm;
Q = (O_1+2{dimensionless}*O_2+3{dimensionless}*O_3+4{dimensionless}*O_4+C_1+2{dimensionless}*C_2+3{dimensionless}*C_3+4{dimensionless}*C_4)/4{dimensionless};
dQ = (dO_1+2{dimensionless}*dO_2+3{dimensionless}*dO_3+4{dimensionless}*dO_4+dC_1+2{dimensionless}*dC_2+3{dimensionless}*dC_3+4{dimensionless}*dC_4)/4{dimensionless};
enddef;
def group as encapsulation for
comp MWC_10 incl
comp C0;
comp C1;
comp C2;
comp C3;
comp C4;
comp O0;
comp O1;
comp O2;
comp O3;
comp O4;
endcomp;
enddef;
def map between C0 and C1 for
vars S_i and S_1;
vars S_2 and S_i;
enddef;
def map between C0 and O0 for
vars S_i and S_1;
vars S_1 and S_i;
enddef;
def map between C0 and MWC_10 for
vars S_i and C_0;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars norm and norm;
vars Si_init and C0_init;
vars N and N;
vars t and t;
enddef;
def map between C1 and C2 for
vars S_i and S_1;
vars S_3 and S_i;
enddef;
def map between C1 and O1 for
vars S_i and S_2;
vars S_2 and S_i;
enddef;
def map between C1 and MWC_10 for
vars S_i and C_1;
vars dS_i and dC_1;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and C1_init;
vars N and N;
vars i and C1_i;
vars t and t;
enddef;
def map between C2 and C3 for
vars S_i and S_1;
vars S_3 and S_i;
enddef;
def map between C2 and O2 for
vars S_i and S_2;
vars S_2 and S_i;
enddef;
def map between C2 and MWC_10 for
vars S_i and C_2;
vars dS_i and dC_2;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and C2_init;
vars N and N;
vars i and C2_i;
vars t and t;
enddef;
def map between C3 and C4 for
vars S_i and S_1;
vars S_3 and S_i;
enddef;
def map between C3 and O3 for
vars S_i and S_2;
vars S_2 and S_i;
enddef;
def map between C3 and MWC_10 for
vars S_i and C_3;
vars dS_i and dC_3;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and C3_init;
vars N and N;
vars i and C3_i;
vars t and t;
enddef;
def map between C4 and O4 for
vars S_i and S_2;
vars S_2 and S_i;
enddef;
def map between C4 and MWC_10 for
vars S_i and C_4;
vars dS_i and dC_4;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and C4_init;
vars N and N;
vars t and t;
enddef;
def map between O0 and O1 for
vars S_i and S_1;
vars S_2 and S_i;
enddef;
def map between O0 and MWC_10 for
vars S_i and O_0;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and O0_init;
vars N and N;
vars t and t;
enddef;
def map between O1 and O2 for
vars S_i and S_1;
vars S_3 and S_i;
enddef;
def map between O1 and MWC_10 for
vars S_i and O_1;
vars dS_i and dO_1;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and O1_init;
vars N and N;
vars i and O1_i;
vars t and t;
enddef;
def map between O2 and O3 for
vars S_i and S_1;
vars S_3 and S_i;
enddef;
def map between O2 and MWC_10 for
vars S_i and O_2;
vars dS_i and dO_2;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and O2_init;
vars N and N;
vars i and O2_i;
vars t and t;
enddef;
def map between O3 and O4 for
vars S_i and S_1;
vars S_3 and S_i;
enddef;
def map between O3 and MWC_10 for
vars S_i and O_3;
vars dS_i and dO_3;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and O3_init;
vars N and N;
vars i and O3_i;
vars t and t;
enddef;
def map between O4 and MWC_10 for
vars S_i and O_4;
vars dS_i and dO_4;
vars k_L and k_L;
vars k_Lminus and k_Lminus;
vars k_C and k_C;
vars k_Cminus and k_Cminus;
vars f and f;
vars norm and norm;
vars Si_init and O4_init;
vars N and N;
vars t and t;
enddef;
enddef;
