Location: BG_NKE @ 043f2808e970 / BG_NaK.cellml

Author:
Shelley Fong <sfon036@UoA.auckland.ac.nz>
Date:
2024-11-08 12:23:21+13:00
Desc:
Adding exposure files and sedml
Permanent Source URI:
https://models.physiomeproject.org/workspace/827/rawfile/043f2808e970d46594145d0d88d04b3822387d4f/BG_NaK.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="cardiac_AP_NaK_only" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="units_and_constants/units_BG.cellml">
        <units name="mM" units_ref="mM"/>
        <units name="fmol" units_ref="fmol"/>
        <units name="per_fmol" units_ref="per_fmol"/>
        <units name="J_per_mol" units_ref="J_per_mol"/>
        <units name="fmol_per_sec" units_ref="fmol_per_sec"/>
        <units name="C_per_mol" units_ref="C_per_mol"/>
        <units name="J_per_C" units_ref="J_per_C"/>
        <units name="J_per_K_per_mol" units_ref="J_per_K_per_mol"/>
        <units name="fF" units_ref="fF"/>
        <units name="fC" units_ref="fC"/>
        <units name="fA" units_ref="fA"/>
    </import>
    <component name="environment">
        <variable initial_value="0" name="t" public_interface="out" units="second"/>
        <variable initial_value="8.314" name="R" public_interface="out" units="J_per_K_per_mol"/>
        <variable initial_value="310" name="T" public_interface="out" units="kelvin"/>
        <variable initial_value="96485" name="F" public_interface="out" units="C_per_mol"/>
        <variable initial_value="153400" name="C_m" public_interface="out" units="fF"/>
        <variable initial_value="27.9828" name="q_K_o" public_interface="out" units="fmol"/>
        <variable initial_value="5510" name="q_K_i" public_interface="out" units="fmol"/>
        <variable initial_value="725.48" name="q_Na_o" public_interface="out" units="fmol"/>
        <variable initial_value="380" name="q_Na_i" public_interface="out" units="fmol"/>
        <variable initial_value="0.0030534" name="q_H_i" public_interface="out" units="fmol"/>
        <variable initial_value="1.33" name="q_MgADP" public_interface="out" units="fmol"/>
        <variable initial_value="264.1" name="q_MgATP" public_interface="out" units="fmol"/>
        <variable initial_value="15.0898" name="q_Pi" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P7" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P14" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P15" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P1" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P2" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P3" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P4" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P5" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P6" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P10" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P11" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P12" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P13" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P8" public_interface="out" units="fmol"/>
        <variable initial_value="0.001126432" name="q_P9" public_interface="out" units="fmol"/>
        <variable name="v_K_o_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_K_i_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_Na_o_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_Na_i_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_H_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_MgADP_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_MgATP_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_Pi_NaK" public_interface="in" units="fmol_per_sec"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_K_o</ci>
                </apply>
                <ci>v_K_o_NaK</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_K_i</ci>
                </apply>
                <ci>v_K_i_NaK</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_Na_o</ci>
                </apply>
                <ci>v_Na_o_NaK</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_Na_i</ci>
                </apply>
                <ci>v_Na_i_NaK</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_H_i</ci>
                </apply>
                <ci>v_H_NaK</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_MgADP</ci>
                </apply>
                <ci>v_MgADP_NaK</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_MgATP</ci>
                </apply>
                <ci>v_MgATP_NaK</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_Pi</ci>
                </apply>
                <ci>v_Pi_NaK</ci>
            </apply>
        </math>
        <variable initial_value="-13039" name="q_mem" public_interface="out" units="fC"/>
        <variable name="q_mem_mNaK" public_interface="in" units="fA"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_mem</ci>
                </apply>
                <ci>q_mem_mNaK</ci>
            </apply>
        </math>
    </component>
    <component name="NaK_parameters">
        <variable initial_value="28701.2" name="kappa_1_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="1.02749e+06" name="kappa_2_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="36989.9" name="kappa_3_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="110769" name="kappa_4_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="143.043" name="kappa_5_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.203578" name="kappa_6_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="73.4728" name="kappa_7_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="70.4896" name="kappa_8_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="19895.6" name="kappa_9_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="1.40388e+06" name="kappa_10_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="7905.94" name="kappa_11_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="6193.15" name="kappa_12_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.55667" name="kappa_13_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="6163.37" name="kappa_14_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="1.34489" name="kappa_15_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="1.17033e+06" name="K_1_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="8172.83" name="K_2_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="228.295" name="K_3_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="76.2363" name="K_4_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="101.833" name="K_5_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="6990.92" name="K_6_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="157.403" name="K_7_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="494.813" name="K_8_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="1.06726e+06" name="K_9_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="3781.29" name="K_10_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="53.588" name="K_11_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="68.4084" name="K_12_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="349.31" name="K_13_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="105.854" name="K_14_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="22775" name="K_15_NaK" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.000123928" name="K_K_i" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.455493" name="K_K_o" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.00344241" name="K_Na_i" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.00256511" name="K_Na_o" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.0445571" name="K_MgATP" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.204939" name="K_MgADP" public_interface="out" units="per_fmol"/>
        <variable initial_value="2.00757" name="K_Pi" public_interface="out" units="per_fmol"/>
        <variable initial_value="2.00757" name="K_H" public_interface="out" units="per_fmol"/>
        <variable initial_value="-5301.979" name="zF_5" public_interface="out" units="C_per_mol"/>
        <variable initial_value="-91183.021" name="zF_8" public_interface="out" units="C_per_mol"/>
    </component>
    <component name="NaK">
        <variable name="t" public_interface="in" units="second"/>
        <variable name="R" public_interface="in" units="J_per_K_per_mol"/>
        <variable name="T" public_interface="in" units="kelvin"/>
        <variable name="F" public_interface="in" units="C_per_mol"/>
        <variable name="C_m" public_interface="in" units="fF"/>
        <variable name="K_10_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_11_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_12_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_13_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_14_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_15_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_1_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_2_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_3_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_4_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_5_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_6_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_7_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_8_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_9_NaK" public_interface="in" units="per_fmol"/>
        <variable name="K_H" public_interface="in" units="per_fmol"/>
        <variable name="K_K_o" public_interface="in" units="per_fmol"/>
        <variable name="K_K_i" public_interface="in" units="per_fmol"/>
        <variable name="K_MgADP" public_interface="in" units="per_fmol"/>
        <variable name="K_MgATP" public_interface="in" units="per_fmol"/>
        <variable name="K_Na_o" public_interface="in" units="per_fmol"/>
        <variable name="K_Na_i" public_interface="in" units="per_fmol"/>
        <variable name="K_Pi" public_interface="in" units="per_fmol"/>
        <variable name="kappa_10_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_11_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_12_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_13_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_14_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_15_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_1_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_2_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_3_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_4_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_5_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_6_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_7_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_8_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_9_NaK" public_interface="in" units="fmol_per_sec"/>
        <variable name="zF_5" public_interface="in" units="C_per_mol"/>
        <variable name="zF_8" public_interface="in" units="C_per_mol"/>
        <variable name="q_K_o" public_interface="in" units="fmol"/>
        <variable name="q_K_i" public_interface="in" units="fmol"/>
        <variable name="q_Na_o" public_interface="in" units="fmol"/>
        <variable name="q_Na_i" public_interface="in" units="fmol"/>
        <variable name="q_H_i" public_interface="in" units="fmol"/>
        <variable name="q_MgADP" public_interface="in" units="fmol"/>
        <variable name="q_MgATP" public_interface="in" units="fmol"/>
        <variable name="q_Pi" public_interface="in" units="fmol"/>
        <variable name="q_P7" public_interface="in" units="fmol"/>
        <variable name="q_P14" public_interface="in" units="fmol"/>
        <variable name="q_P15" public_interface="in" units="fmol"/>
        <variable name="q_P1" public_interface="in" units="fmol"/>
        <variable name="q_P2" public_interface="in" units="fmol"/>
        <variable name="q_P3" public_interface="in" units="fmol"/>
        <variable name="q_P4" public_interface="in" units="fmol"/>
        <variable name="q_P5" public_interface="in" units="fmol"/>
        <variable name="q_P6" public_interface="in" units="fmol"/>
        <variable name="q_P10" public_interface="in" units="fmol"/>
        <variable name="q_P11" public_interface="in" units="fmol"/>
        <variable name="q_P12" public_interface="in" units="fmol"/>
        <variable name="q_P13" public_interface="in" units="fmol"/>
        <variable name="q_P8" public_interface="in" units="fmol"/>
        <variable name="q_P9" public_interface="in" units="fmol"/>
        <variable name="q_mem" public_interface="in" units="fC"/>
        <variable name="mu_K_o" units="J_per_mol"/>
        <variable name="mu_K_i" units="J_per_mol"/>
        <variable name="mu_Na_o" units="J_per_mol"/>
        <variable name="mu_Na_i" units="J_per_mol"/>
        <variable name="mu_H" units="J_per_mol"/>
        <variable name="mu_MgADP" units="J_per_mol"/>
        <variable name="mu_MgATP" units="J_per_mol"/>
        <variable name="mu_P7" units="J_per_mol"/>
        <variable name="mu_Pi" units="J_per_mol"/>
        <variable name="mu_P14" units="J_per_mol"/>
        <variable name="mu_P15" units="J_per_mol"/>
        <variable name="mu_P1" units="J_per_mol"/>
        <variable name="mu_P2" units="J_per_mol"/>
        <variable name="mu_P3" units="J_per_mol"/>
        <variable name="mu_P4" units="J_per_mol"/>
        <variable name="mu_P5" units="J_per_mol"/>
        <variable name="mu_P6" units="J_per_mol"/>
        <variable name="mu_P10" units="J_per_mol"/>
        <variable name="mu_P11" units="J_per_mol"/>
        <variable name="mu_P12" units="J_per_mol"/>
        <variable name="mu_P13" units="J_per_mol"/>
        <variable name="mu_P8" units="J_per_mol"/>
        <variable name="mu_P9" units="J_per_mol"/>
        <variable name="v_P14" units="fmol_per_sec"/>
        <variable name="v_P15" units="fmol_per_sec"/>
        <variable name="v_P1" units="fmol_per_sec"/>
        <variable name="v_P2" units="fmol_per_sec"/>
        <variable name="v_P3" units="fmol_per_sec"/>
        <variable name="v_P4" units="fmol_per_sec"/>
        <variable name="v_P5" units="fmol_per_sec"/>
        <variable name="v_P6" units="fmol_per_sec"/>
        <variable name="v_P10" units="fmol_per_sec"/>
        <variable name="v_P11" units="fmol_per_sec"/>
        <variable name="v_P12" units="fmol_per_sec"/>
        <variable name="v_P13" units="fmol_per_sec"/>
        <variable name="v_P7" units="fmol_per_sec"/>
        <variable name="v_P8" units="fmol_per_sec"/>
        <variable name="v_P9" units="fmol_per_sec"/>
        <variable name="v_K_o_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_K_i_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_Na_o_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_Na_i_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_H_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_MgADP_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_MgATP_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_Pi_NaK" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R1" units="J_per_mol"/>
        <variable name="Ar_R1" units="J_per_mol"/>
        <variable name="v_R1" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R10" units="J_per_mol"/>
        <variable name="Ar_R10" units="J_per_mol"/>
        <variable name="v_R10" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R11" units="J_per_mol"/>
        <variable name="Ar_R11" units="J_per_mol"/>
        <variable name="v_R11" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R12" units="J_per_mol"/>
        <variable name="Ar_R12" units="J_per_mol"/>
        <variable name="v_R12" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R13" units="J_per_mol"/>
        <variable name="Ar_R13" units="J_per_mol"/>
        <variable name="v_R13" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R14" units="J_per_mol"/>
        <variable name="Ar_R14" units="J_per_mol"/>
        <variable name="v_R14" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R15" units="J_per_mol"/>
        <variable name="Ar_R15" units="J_per_mol"/>
        <variable name="v_R15" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R2" units="J_per_mol"/>
        <variable name="Ar_R2" units="J_per_mol"/>
        <variable name="v_R2" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R3" units="J_per_mol"/>
        <variable name="Ar_R3" units="J_per_mol"/>
        <variable name="v_R3" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R4" units="J_per_mol"/>
        <variable name="Ar_R4" units="J_per_mol"/>
        <variable name="v_R4" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R5" units="J_per_mol"/>
        <variable name="Ar_R5" units="J_per_mol"/>
        <variable name="v_R5" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R6" units="J_per_mol"/>
        <variable name="Ar_R6" units="J_per_mol"/>
        <variable name="v_R6" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R7" units="J_per_mol"/>
        <variable name="Ar_R7" units="J_per_mol"/>
        <variable name="v_R7" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R8" units="J_per_mol"/>
        <variable name="Ar_R8" units="J_per_mol"/>
        <variable name="v_R8" public_interface="out" units="fmol_per_sec"/>
        <variable name="Af_R9" units="J_per_mol"/>
        <variable name="Ar_R9" units="J_per_mol"/>
        <variable name="v_R9" public_interface="out" units="fmol_per_sec"/>
        <variable name="V_mem" units="volt"/>
        <variable name="I_mem_NaK" public_interface="out" units="fA"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>V_mem</ci>
                <apply>
                    <divide/>
                    <ci>q_mem</ci>
                    <ci>C_m</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>I_mem_NaK</ci>
                <apply>
                    <plus/>
                    <apply>
                        <times/>
                        <ci>zF_8</ci>
                        <ci>v_R8</ci>
                    </apply>
                    <apply>
                        <times/>
                        <ci>zF_5</ci>
                        <ci>v_R5</ci>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_H</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_H</ci>
                            <ci>q_H_i</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_K_o</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_K_o</ci>
                            <ci>q_K_o</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_K_i</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_K_i</ci>
                            <ci>q_K_i</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_MgADP</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_MgADP</ci>
                            <ci>q_MgADP</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_MgATP</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_MgATP</ci>
                            <ci>q_MgATP</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_Na_o</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_Na_o</ci>
                            <ci>q_Na_o</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_Na_i</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_Na_i</ci>
                            <ci>q_Na_i</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P1</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_1_NaK</ci>
                            <ci>q_P1</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P10</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_10_NaK</ci>
                            <ci>q_P10</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P11</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_11_NaK</ci>
                            <ci>q_P11</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P12</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_12_NaK</ci>
                            <ci>q_P12</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P13</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_13_NaK</ci>
                            <ci>q_P13</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P14</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_14_NaK</ci>
                            <ci>q_P14</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P15</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_15_NaK</ci>
                            <ci>q_P15</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P2</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_2_NaK</ci>
                            <ci>q_P2</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P3</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_3_NaK</ci>
                            <ci>q_P3</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P4</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_4_NaK</ci>
                            <ci>q_P4</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P5</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_5_NaK</ci>
                            <ci>q_P5</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P6</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_6_NaK</ci>
                            <ci>q_P6</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P7</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_7_NaK</ci>
                            <ci>q_P7</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P8</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_8_NaK</ci>
                            <ci>q_P8</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_P9</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_9_NaK</ci>
                            <ci>q_P9</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_Pi</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_Pi</ci>
                            <ci>q_Pi</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R1</ci>
                <apply>
                    <times/>
                    <ci>kappa_1_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R1</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R1</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R10</ci>
                <apply>
                    <times/>
                    <ci>kappa_10_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R10</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R10</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R11</ci>
                <apply>
                    <times/>
                    <ci>kappa_11_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R11</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R11</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R12</ci>
                <apply>
                    <times/>
                    <ci>kappa_12_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R12</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R12</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R13</ci>
                <apply>
                    <times/>
                    <ci>kappa_13_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R13</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R13</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R14</ci>
                <apply>
                    <times/>
                    <ci>kappa_14_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R14</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R14</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R15</ci>
                <apply>
                    <times/>
                    <ci>kappa_15_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R15</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R15</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R2</ci>
                <apply>
                    <times/>
                    <ci>kappa_2_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R2</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R2</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R3</ci>
                <apply>
                    <times/>
                    <ci>kappa_3_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R3</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R3</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R4</ci>
                <apply>
                    <times/>
                    <ci>kappa_4_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R4</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R4</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R5</ci>
                <apply>
                    <times/>
                    <ci>kappa_5_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R5</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R5</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R6</ci>
                <apply>
                    <times/>
                    <ci>kappa_6_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R6</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R6</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R7</ci>
                <apply>
                    <times/>
                    <ci>kappa_7_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R7</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R7</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R8</ci>
                <apply>
                    <times/>
                    <ci>kappa_8_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R8</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R8</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R9</ci>
                <apply>
                    <times/>
                    <ci>kappa_9_NaK</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Af_R9</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>Ar_R9</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R1</ci>
                <ci>mu_P1</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R10</ci>
                <ci>mu_P10</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R11</ci>
                <apply>
                    <plus/>
                    <ci>mu_P11</ci>
                    <ci>mu_K_o</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R12</ci>
                <apply>
                    <plus/>
                    <ci>mu_P12</ci>
                    <ci>mu_K_o</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R13</ci>
                <ci>mu_P13</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R14</ci>
                <apply>
                    <plus/>
                    <ci>mu_P14</ci>
                    <ci>mu_MgATP</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R15</ci>
                <ci>mu_P15</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R2</ci>
                <ci>mu_P2</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R3</ci>
                <apply>
                    <plus/>
                    <ci>mu_P3</ci>
                    <ci>mu_Na_i</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R4</ci>
                <apply>
                    <plus/>
                    <ci>mu_P4</ci>
                    <ci>mu_Na_i</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R5</ci>
                <apply>
                    <plus/>
                    <ci>mu_P5</ci>
                    <ci>mu_Na_i</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R6</ci>
                <ci>mu_P6</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R7</ci>
                <ci>mu_P7</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R8</ci>
                <ci>mu_P8</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Af_R9</ci>
                <ci>mu_P9</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R1</ci>
                <apply>
                    <plus/>
                    <ci>mu_K_i</ci>
                    <ci>mu_P2</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R10</ci>
                <apply>
                    <plus/>
                    <ci>mu_Na_o</ci>
                    <ci>mu_P11</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R11</ci>
                <ci>mu_P12</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R12</ci>
                <ci>mu_P13</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R13</ci>
                <apply>
                    <plus/>
                    <ci>mu_H</ci>
                    <ci>mu_Pi</ci>
                    <ci>mu_P14</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R14</ci>
                <ci>mu_P15</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R15</ci>
                <ci>mu_P1</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R2</ci>
                <apply>
                    <plus/>
                    <ci>mu_P3</ci>
                    <ci>mu_K_i</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R3</ci>
                <ci>mu_P4</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R4</ci>
                <ci>mu_P5</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R5</ci>
                <apply>
                    <plus/>
                    <apply>
                        <times/>
                        <ci>R</ci>
                        <ci>T</ci>
                        <apply>
                            <ln/>
                            <apply>
                                <times/>
                                <ci>K_6_NaK</ci>
                                <ci>q_P6</ci>
                            </apply>
                        </apply>
                    </apply>
                    <apply>
                        <times/>
                        <ci>zF_5</ci>
                        <ci>V_mem</ci>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R6</ci>
                <apply>
                    <plus/>
                    <ci>mu_P7</ci>
                    <ci>mu_MgADP</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R7</ci>
                <ci>mu_P8</ci>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R8</ci>
                <apply>
                    <plus/>
                    <apply>
                        <times/>
                        <ci>zF_8</ci>
                        <ci>V_mem</ci>
                    </apply>
                    <apply>
                        <times/>
                        <ci>R</ci>
                        <ci>T</ci>
                        <apply>
                            <ln/>
                            <apply>
                                <times/>
                                <ci>K_Na_o</ci>
                                <ci>q_Na_o</ci>
                            </apply>
                        </apply>
                    </apply>
                    <apply>
                        <times/>
                        <ci>R</ci>
                        <ci>T</ci>
                        <apply>
                            <ln/>
                            <apply>
                                <times/>
                                <ci>K_9_NaK</ci>
                                <ci>q_P9</ci>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Ar_R9</ci>
                <apply>
                    <plus/>
                    <ci>mu_P10</ci>
                    <ci>mu_Na_o</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_H_NaK</ci>
                <ci>v_R13</ci>
            </apply>
            <apply>
                <eq/>
                <ci>v_K_o_NaK</ci>
                <apply>
                    <minus/>
                    <apply>
                        <minus/>
                        <ci>v_R11</ci>
                    </apply>
                    <ci>v_R12</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_K_i_NaK</ci>
                <apply>
                    <plus/>
                    <ci>v_R1</ci>
                    <ci>v_R2</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_MgADP_NaK</ci>
                <ci>v_R6</ci>
            </apply>
            <apply>
                <eq/>
                <ci>v_MgATP_NaK</ci>
                <apply>
                    <minus/>
                    <ci>v_R14</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_Na_o_NaK</ci>
                <apply>
                    <plus/>
                    <ci>v_R8</ci>
                    <ci>v_R9</ci>
                    <ci>v_R10</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_Na_i_NaK</ci>
                <apply>
                    <minus/>
                    <apply>
                        <minus/>
                        <ci>v_R3</ci>
                    </apply>
                    <apply>
                        <plus/>
                        <ci>v_R4</ci>
                        <ci>v_R5</ci>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P1</ci>
                <apply>
                    <plus/>
                    <apply>
                        <minus/>
                        <ci>v_R1</ci>
                    </apply>
                    <ci>v_R15</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P10</ci>
                <apply>
                    <minus/>
                    <ci>v_R9</ci>
                    <ci>v_R10</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P11</ci>
                <apply>
                    <minus/>
                    <ci>v_R10</ci>
                    <ci>v_R11</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P12</ci>
                <apply>
                    <plus/>
                    <apply>
                        <minus/>
                        <ci>v_R12</ci>
                    </apply>
                    <ci>v_R11</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P13</ci>
                <apply>
                    <minus/>
                    <ci>v_R12</ci>
                    <ci>v_R13</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P14</ci>
                <apply>
                    <plus/>
                    <apply>
                        <minus/>
                        <ci>v_R14</ci>
                    </apply>
                    <ci>v_R13</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P15</ci>
                <apply>
                    <minus/>
                    <ci>v_R14</ci>
                    <ci>v_R15</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P2</ci>
                <apply>
                    <plus/>
                    <apply>
                        <minus/>
                        <ci>v_R2</ci>
                    </apply>
                    <ci>v_R1</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P3</ci>
                <apply>
                    <minus/>
                    <ci>v_R2</ci>
                    <ci>v_R3</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P4</ci>
                <apply>
                    <minus/>
                    <ci>v_R3</ci>
                    <ci>v_R4</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P5</ci>
                <apply>
                    <minus/>
                    <ci>v_R4</ci>
                    <ci>v_R5</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P6</ci>
                <apply>
                    <minus/>
                    <ci>v_R5</ci>
                    <ci>v_R6</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P7</ci>
                <apply>
                    <minus/>
                    <ci>v_R6</ci>
                    <ci>v_R7</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P8</ci>
                <apply>
                    <plus/>
                    <apply>
                        <minus/>
                        <ci>v_R8</ci>
                    </apply>
                    <ci>v_R7</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_P9</ci>
                <apply>
                    <minus/>
                    <ci>v_R8</ci>
                    <ci>v_R9</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_Pi_NaK</ci>
                <ci>v_R13</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P7</ci>
                </apply>
                <ci>v_P7</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P14</ci>
                </apply>
                <ci>v_P14</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P15</ci>
                </apply>
                <ci>v_P15</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P1</ci>
                </apply>
                <ci>v_P1</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P2</ci>
                </apply>
                <ci>v_P2</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P3</ci>
                </apply>
                <ci>v_P3</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P4</ci>
                </apply>
                <ci>v_P4</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P5</ci>
                </apply>
                <ci>v_P5</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P6</ci>
                </apply>
                <ci>v_P6</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P10</ci>
                </apply>
                <ci>v_P10</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P11</ci>
                </apply>
                <ci>v_P11</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P12</ci>
                </apply>
                <ci>v_P12</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P13</ci>
                </apply>
                <ci>v_P13</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P8</ci>
                </apply>
                <ci>v_P8</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_P9</ci>
                </apply>
                <ci>v_P9</ci>
            </apply>
        </math>
    </component>
    <connection>
        <map_components component_1="NaK" component_2="NaK_parameters"/>
        <map_variables variable_1="K_10_NaK" variable_2="K_10_NaK"/>
        <map_variables variable_1="K_11_NaK" variable_2="K_11_NaK"/>
        <map_variables variable_1="K_12_NaK" variable_2="K_12_NaK"/>
        <map_variables variable_1="K_13_NaK" variable_2="K_13_NaK"/>
        <map_variables variable_1="K_14_NaK" variable_2="K_14_NaK"/>
        <map_variables variable_1="K_15_NaK" variable_2="K_15_NaK"/>
        <map_variables variable_1="K_1_NaK" variable_2="K_1_NaK"/>
        <map_variables variable_1="K_2_NaK" variable_2="K_2_NaK"/>
        <map_variables variable_1="K_3_NaK" variable_2="K_3_NaK"/>
        <map_variables variable_1="K_4_NaK" variable_2="K_4_NaK"/>
        <map_variables variable_1="K_5_NaK" variable_2="K_5_NaK"/>
        <map_variables variable_1="K_6_NaK" variable_2="K_6_NaK"/>
        <map_variables variable_1="K_7_NaK" variable_2="K_7_NaK"/>
        <map_variables variable_1="K_8_NaK" variable_2="K_8_NaK"/>
        <map_variables variable_1="K_9_NaK" variable_2="K_9_NaK"/>
        <map_variables variable_1="K_H" variable_2="K_H"/>
        <map_variables variable_1="K_K_o" variable_2="K_K_o"/>
        <map_variables variable_1="K_K_i" variable_2="K_K_i"/>
        <map_variables variable_1="K_MgADP" variable_2="K_MgADP"/>
        <map_variables variable_1="K_MgATP" variable_2="K_MgATP"/>
        <map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
        <map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
        <map_variables variable_1="K_Pi" variable_2="K_Pi"/>
        <map_variables variable_1="kappa_10_NaK" variable_2="kappa_10_NaK"/>
        <map_variables variable_1="kappa_11_NaK" variable_2="kappa_11_NaK"/>
        <map_variables variable_1="kappa_12_NaK" variable_2="kappa_12_NaK"/>
        <map_variables variable_1="kappa_13_NaK" variable_2="kappa_13_NaK"/>
        <map_variables variable_1="kappa_14_NaK" variable_2="kappa_14_NaK"/>
        <map_variables variable_1="kappa_15_NaK" variable_2="kappa_15_NaK"/>
        <map_variables variable_1="kappa_1_NaK" variable_2="kappa_1_NaK"/>
        <map_variables variable_1="kappa_2_NaK" variable_2="kappa_2_NaK"/>
        <map_variables variable_1="kappa_3_NaK" variable_2="kappa_3_NaK"/>
        <map_variables variable_1="kappa_4_NaK" variable_2="kappa_4_NaK"/>
        <map_variables variable_1="kappa_5_NaK" variable_2="kappa_5_NaK"/>
        <map_variables variable_1="kappa_6_NaK" variable_2="kappa_6_NaK"/>
        <map_variables variable_1="kappa_7_NaK" variable_2="kappa_7_NaK"/>
        <map_variables variable_1="kappa_8_NaK" variable_2="kappa_8_NaK"/>
        <map_variables variable_1="kappa_9_NaK" variable_2="kappa_9_NaK"/>
        <map_variables variable_1="zF_5" variable_2="zF_5"/>
        <map_variables variable_1="zF_8" variable_2="zF_8"/>
    </connection>
    <connection>
        <map_components component_1="NaK" component_2="environment"/>
        <map_variables variable_1="t" variable_2="t"/>
        <map_variables variable_1="R" variable_2="R"/>
        <map_variables variable_1="T" variable_2="T"/>
        <map_variables variable_1="F" variable_2="F"/>
        <map_variables variable_1="C_m" variable_2="C_m"/>
        <map_variables variable_1="q_K_o" variable_2="q_K_o"/>
        <map_variables variable_1="q_K_i" variable_2="q_K_i"/>
        <map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
        <map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
        <map_variables variable_1="q_H_i" variable_2="q_H_i"/>
        <map_variables variable_1="q_MgADP" variable_2="q_MgADP"/>
        <map_variables variable_1="q_MgATP" variable_2="q_MgATP"/>
        <map_variables variable_1="q_Pi" variable_2="q_Pi"/>
        <map_variables variable_1="q_P7" variable_2="q_P7"/>
        <map_variables variable_1="q_P14" variable_2="q_P14"/>
        <map_variables variable_1="q_P15" variable_2="q_P15"/>
        <map_variables variable_1="q_P1" variable_2="q_P1"/>
        <map_variables variable_1="q_P2" variable_2="q_P2"/>
        <map_variables variable_1="q_P3" variable_2="q_P3"/>
        <map_variables variable_1="q_P4" variable_2="q_P4"/>
        <map_variables variable_1="q_P5" variable_2="q_P5"/>
        <map_variables variable_1="q_P6" variable_2="q_P6"/>
        <map_variables variable_1="q_P10" variable_2="q_P10"/>
        <map_variables variable_1="q_P11" variable_2="q_P11"/>
        <map_variables variable_1="q_P12" variable_2="q_P12"/>
        <map_variables variable_1="q_P13" variable_2="q_P13"/>
        <map_variables variable_1="q_P8" variable_2="q_P8"/>
        <map_variables variable_1="q_P9" variable_2="q_P9"/>
        <map_variables variable_1="v_K_o_NaK" variable_2="v_K_o_NaK"/>
        <map_variables variable_1="v_K_i_NaK" variable_2="v_K_i_NaK"/>
        <map_variables variable_1="v_Na_o_NaK" variable_2="v_Na_o_NaK"/>
        <map_variables variable_1="v_Na_i_NaK" variable_2="v_Na_i_NaK"/>
        <map_variables variable_1="v_H_NaK" variable_2="v_H_NaK"/>
        <map_variables variable_1="v_MgADP_NaK" variable_2="v_MgADP_NaK"/>
        <map_variables variable_1="v_MgATP_NaK" variable_2="v_MgATP_NaK"/>
        <map_variables variable_1="v_Pi_NaK" variable_2="v_Pi_NaK"/>
        <map_variables variable_1="q_mem" variable_2="q_mem"/>
        <map_variables variable_1="I_mem_NaK" variable_2="q_mem_mNaK"/>
    </connection>
</model>