Location: Model of excitation-contraction in uterine myocytes from a pregnant rat @ fc955f944a55 / Components / IK2_gating.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2021-09-21 18:51:37+12:00
Desc:
add CB4HM_Cai
Permanent Source URI:
https://models.physiomeproject.org/workspace/701/rawfile/fc955f944a555bf8c64a88ab136430dec8f1383e/Components/IK2_gating.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="IK2_gating" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="../cellLib/Components/units.cellml">
        <units name="mV" units_ref="mV"/>
        <units name="ms" units_ref="ms"/>
    </import>
    <component name="p_inf">
        <variable name="X_inf" public_interface="out" units="dimensionless"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>X_inf</ci>
                <apply>
                    <divide/>
                    <cn cellml:units="dimensionless">1</cn>
                    <apply>
                        <plus/>
                        <cn cellml:units="dimensionless">1</cn>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <apply>
                                        <minus/>
                                        <ci>V</ci>
                                    </apply>
                                    <cn cellml:units="mV">4.2</cn>
                                </apply>
                                <cn cellml:units="mV">23</cn>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="k_inf">
        <variable name="X_inf" public_interface="out" units="dimensionless"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>X_inf</ci>
                <apply>
                    <divide/>
                    <cn cellml:units="dimensionless">1</cn>
                    <apply>
                        <plus/>
                        <cn cellml:units="dimensionless">1</cn>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>V</ci>
                                    <cn cellml:units="mV">21.2</cn>
                                </apply>
                                <cn cellml:units="mV">5.7</cn>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="tau_p">
        <variable name="tau" public_interface="out" units="ms"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>tau</ci>
                <apply>
                    <divide/>
                    <cn cellml:units="ms">100</cn>
                    <apply>
                        <plus/>
                        <cn cellml:units="dimensionless">1</cn>
                        <apply>
                            <power/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>V</ci>
                                    <cn cellml:units="mV">64.1</cn>
                                </apply>
                                <cn cellml:units="mV">28.67</cn>
                            </apply>
                            <cn cellml:units="dimensionless">2</cn>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="tau_k1">
        <variable name="tau" public_interface="out" units="ms"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>tau</ci>
                <apply>
                    <minus/>
                    <cn cellml:units="ms" type="e-notation">1<sep/>6</cn>
                    <apply>
                        <divide/>
                        <cn cellml:units="ms" type="e-notation">1<sep/>6</cn>
                        <apply>
                            <times/>
                            <apply>
                                <plus/>
                                <cn cellml:units="dimensionless">1</cn>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <minus/>
                                            <ci>V</ci>
                                            <cn cellml:units="mV">315</cn>
                                        </apply>
                                        <cn cellml:units="mV">50</cn>
                                    </apply>
                                </apply>
                            </apply>
                            <apply>
                                <plus/>
                                <cn cellml:units="dimensionless">1</cn>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <minus/>
                                            <apply>
                                                <minus/>
                                                <ci>V</ci>
                                            </apply>
                                            <cn cellml:units="mV">74.9</cn>
                                        </apply>
                                        <cn cellml:units="mV">8</cn>
                                    </apply>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="tau_k2">
        <variable name="tau" public_interface="out" units="ms"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>tau</ci>
                <apply>
                    <minus/>
                    <cn cellml:units="ms" type="e-notation">2.5<sep/>6</cn>
                    <apply>
                        <divide/>
                        <cn cellml:units="ms" type="e-notation">2.5<sep/>6</cn>
                        <apply>
                            <times/>
                            <apply>
                                <plus/>
                                <cn cellml:units="dimensionless">1</cn>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <minus/>
                                            <ci>V</ci>
                                            <cn cellml:units="mV">132.87</cn>
                                        </apply>
                                        <cn cellml:units="mV">25.4</cn>
                                    </apply>
                                </apply>
                            </apply>
                            <apply>
                                <plus/>
                                <cn cellml:units="dimensionless">1</cn>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <minus/>
                                            <apply>
                                                <minus/>
                                                <ci>V</ci>
                                            </apply>
                                            <cn cellml:units="mV">24.92</cn>
                                        </apply>
                                        <cn cellml:units="mV">2.68</cn>
                                    </apply>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
</model>