Location: Model of excitation-contraction in uterine myocytes from a pregnant rat @ f5b5a6cc798b / Components / IKA_gating.cellml

Author:

WeiweiAi <wai484@aucklanduni.ac.nz>

Date:

2021-09-29 14:19:13+13:00

Desc:

correct the interface def and add individual currents for clamp experiment

Permanent Source URI:

https://models.physiomeproject.org/workspace/701/rawfile/f5b5a6cc798b55f4a6f6a30cc839d5698a5a598c/Components/IKA_gating.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="IKA_gating" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="../cellLib/Components/units.cellml">
        <units name="mV" units_ref="mV"/>
        <units name="ms" units_ref="ms"/>
    </import>
    <component name="s_inf">
        <variable name="X_inf" public_interface="out" units="dimensionless"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>X_inf</ci>
                <apply>
                    <divide/>
                    <cn cellml:units="dimensionless">1</cn>
                    <apply>
                        <plus/>
                        <cn cellml:units="dimensionless">1</cn>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <minus/>
                                    <apply>
                                        <minus/>
                                        <ci>V</ci>
                                    </apply>
                                    <cn cellml:units="mV">27.79</cn>
                                </apply>
                                <cn cellml:units="mV">7.57</cn>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="x_inf">
        <variable name="X_inf" public_interface="out" units="dimensionless"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>X_inf</ci>
                <apply>
                    <plus/>
                    <cn cellml:units="dimensionless">0.3293</cn>
                    <apply>
                        <divide/>
                        <cn cellml:units="dimensionless">0.71165</cn>
                        <apply>
                            <plus/>
                            <cn cellml:units="dimensionless">1</cn>
                            <apply>
                                <exp/>
                                <apply>
                                    <divide/>
                                    <apply>
                                        <plus/>
                                        <ci>V</ci>
                                        <cn cellml:units="mV">53.919</cn>
                                    </apply>
                                    <cn cellml:units="mV">7.8111</cn>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="tau_s">
        <variable name="tau" public_interface="out" units="ms"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>tau</ci>
                <apply>
                    <divide/>
                    <cn cellml:units="ms">17</cn>
                    <apply>
                        <plus/>
                        <cn cellml:units="dimensionless">1</cn>
                        <apply>
                            <power/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>V</ci>
                                    <cn cellml:units="mV">20.52</cn>
                                </apply>
                                <cn cellml:units="mV">35</cn>
                            </apply>
                            <cn cellml:units="dimensionless">2</cn>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="tau_x">
        <variable name="tau" public_interface="out" units="ms"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>tau</ci>
                <apply>
                    <plus/>
                    <cn cellml:units="ms">7.5</cn>
                    <apply>
                        <divide/>
                        <cn cellml:units="ms">10</cn>
                        <apply>
                            <plus/>
                            <cn cellml:units="dimensionless">1</cn>
                            <apply>
                                <power/>
                                <apply>
                                    <divide/>
                                    <apply>
                                        <plus/>
                                        <ci>V</ci>
                                        <cn cellml:units="mV">34.18</cn>
                                    </apply>
                                    <cn cellml:units="mV">120</cn>
                                </apply>
                                <cn cellml:units="dimensionless">2</cn>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
</model>