- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-09-29 14:19:13+13:00
- Desc:
- correct the interface def and add individual currents for clamp experiment
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/701/rawfile/f5b5a6cc798b55f4a6f6a30cc839d5698a5a598c/Components/Cai.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="Cai" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="../cellLib/Components/units.cellml">
<units name="mM" units_ref="mM"/>
<units name="ms" units_ref="ms"/>
<units name="pA_per_pF" units_ref="pA_per_pF"/>
<units name="pA" units_ref="pA"/>
<units name="C_per_mmol" units_ref="C_per_mmol"/>
<units name="pF_per_cmsq" units_ref="pF_per_cmsq"/>
<units name="cmsq" units_ref="cmsq"/>
<units name="cm3" units_ref="cm3"/>
</import>
<import xlink:href="../cellLib/Components/Xi.cellml">
<component component_ref="Xi" name="Xi"/>
</import>
<component name="Cai">
<variable name="time" private_interface="out" public_interface="in" units="ms"/>
<variable name="Cai_init" private_interface="out" public_interface="in" units="mM"/>
<variable name="ICa_tot" private_interface="out" public_interface="in" units="pA_per_pF"/>
<variable name="Cm" private_interface="out" public_interface="in" units="pF_per_cmsq"/>
<variable name="Ac" private_interface="out" public_interface="in" units="cmsq"/>
<variable name="z_Ca" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="F" private_interface="out" public_interface="in" units="C_per_mmol"/>
<variable name="Vc" private_interface="out" public_interface="in" units="cm3"/>
<variable name="Cai" private_interface="in" public_interface="out" units="mM"/>
<variable name="F_BCa" public_interface="in" units="dimensionless"/>
<variable name="S_CM" public_interface="in" units="mM"/>
<variable name="B_F" public_interface="in" units="mM"/>
<variable name="K_d" public_interface="in" units="mM"/>
<variable name="K_dB" public_interface="in" units="mM"/>
<variable name="ICa_totm" private_interface="out" units="pA_per_pF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICa_totm</ci>
<apply>
<times/>
<ci>ICa_tot</ci>
<ci>F_BCa</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<ci>S_CM</ci>
<ci>K_d</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>K_d</ci>
<ci>Cai</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>B_F</ci>
<ci>K_dB</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>K_dB</ci>
<ci>Cai</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="Cai">
<component_ref component="Xi"/>
</component_ref>
</group>
<connection>
<map_components component_1="Cai" component_2="Xi"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Cai_init" variable_2="Xi_init"/>
<map_variables variable_1="ICa_totm" variable_2="IX_tot"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="z_Ca" variable_2="z_X"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vc" variable_2="Vc"/>
<map_variables variable_1="Cai" variable_2="Xi"/>
</connection>
</model>
