- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-09-15 10:52:00+12:00
- Desc:
- Add intracellular concentrations
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/701/rawfile/5eb92ff17b0b2907de48a0950e613845781bf4e9/Components/INaKCl.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="INaKCl" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="../cellLib/Components/units.cellml">
<units name="pA_per_pF" units_ref="pA_per_pF"/>
<units name="pA" units_ref="pA"/>
<units name="mM" units_ref="mM"/>
<units name="cmsq" units_ref="cmsq"/>
<units name="C_per_mmol" units_ref="C_per_mmol"/>
<units name="J_per_K_mol" units_ref="J_per_K_mol"/>
</import>
<units name="mmol2_per_J_s_cmsq_F">
<unit exponent="2" prefix="milli" units="mole"/>
<unit exponent="-1" units="joule"/>
<unit exponent="-1" units="second"/>
<unit exponent="-1" units="cmsq"/>
<unit exponent="-1" units="farad"/>
</units>
<component name="INaKCl">
<variable name="I_NaKCl" public_interface="out" units="pA_per_pF"/>
<variable name="I_NaKCl_Na" public_interface="out" units="pA_per_pF"/>
<variable name="I_NaKCl_K" public_interface="out" units="pA_per_pF"/>
<variable name="R" public_interface="in" units="J_per_K_mol"/>
<variable name="F" public_interface="in" units="C_per_mmol"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="Ac" public_interface="in" units="cmsq"/>
<variable initial_value="-1" name="z_Cl" units="dimensionless"/>
<variable name="R_NaKCl" public_interface="in" units="dimensionless"/>
<variable name="L_NaKCl" public_interface="in" units="mmol2_per_J_s_cmsq_F"/>
<variable name="Nai" public_interface="in" units="mM"/>
<variable name="Nao" public_interface="in" units="mM"/>
<variable name="Ki" public_interface="in" units="mM"/>
<variable name="Ko" public_interface="in" units="mM"/>
<variable name="Cli" public_interface="in" units="mM"/>
<variable name="Clo" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>I_NaKCl</ci>
<apply>
<times/>
<apply>
<minus/>
<ci>R_NaKCl</ci>
</apply>
<ci>z_Cl</ci>
<ci>Ac</ci>
<ci>L_NaKCl</ci>
<ci>R</ci>
<ci>F</ci>
<ci>T</ci>
<apply>
<ln/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Nao</ci>
<ci>Ko</ci>
</apply>
<apply>
<times/>
<ci>Nai</ci>
<ci>Ki</ci>
</apply>
</apply>
<apply>
<power/>
<apply>
<divide/>
<ci>Clo</ci>
<ci>Cli</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>I_NaKCl_Na</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">0.5</cn>
</apply>
<ci>I_NaKCl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>I_NaKCl_K</ci>
<ci>I_NaKCl_Na</ci>
</apply>
</math>
</component>
</model>
