Location: Model of excitation-contraction in uterine myocytes from a pregnant rat @ 5eb92ff17b0b / Components / ICaL_gating.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2021-09-15 10:52:00+12:00
Desc:
Add intracellular concentrations
Permanent Source URI:
https://models.physiomeproject.org/workspace/701/rawfile/5eb92ff17b0b2907de48a0950e613845781bf4e9/Components/ICaL_gating.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="ICaL_gating" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="../cellLib/Components/units.cellml">
        <units name="mV" units_ref="mV"/>
        <units name="ms" units_ref="ms"/>
    </import>
    <component name="d_inf">
        <variable name="X_inf" public_interface="out" units="dimensionless"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>X_inf</ci>
                <apply>
                    <divide/>
                    <cn cellml:units="dimensionless">1</cn>
                    <apply>
                        <plus/>
                        <cn cellml:units="dimensionless">1</cn>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <minus/>
                                    <apply>
                                        <plus/>
                                        <ci>V</ci>
                                        <cn cellml:units="mV">22</cn>
                                    </apply>
                                </apply>
                                <cn cellml:units="mV">7</cn>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="f_inf">
        <variable name="X_inf" public_interface="out" units="dimensionless"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>X_inf</ci>
                <apply>
                    <divide/>
                    <cn cellml:units="dimensionless">1</cn>
                    <apply>
                        <plus/>
                        <cn cellml:units="dimensionless">1</cn>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>V</ci>
                                    <cn cellml:units="mV">33</cn>
                                </apply>
                                <cn cellml:units="mV">7</cn>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="tau_d">
        <variable name="tau" public_interface="out" units="ms"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>tau</ci>
                <apply>
                    <plus/>
                    <cn cellml:units="ms">2.29</cn>
                    <apply>
                        <divide/>
                        <cn cellml:units="ms">5.7</cn>
                        <apply>
                            <plus/>
                            <cn cellml:units="dimensionless">1</cn>
                            <apply>
                                <power/>
                                <apply>
                                    <divide/>
                                    <apply>
                                        <plus/>
                                        <ci>V</ci>
                                        <cn cellml:units="mV">29.97</cn>
                                    </apply>
                                    <cn cellml:units="mV">9</cn>
                                </apply>
                                <cn cellml:units="dimensionless">2</cn>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <component name="tau_f2">
        <variable name="tau" public_interface="out" units="ms"/>
        <variable name="V" public_interface="in" units="mV"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>tau</ci>
                <apply>
                    <minus/>
                    <cn cellml:units="ms">90.97</cn>
                    <apply>
                        <divide/>
                        <cn cellml:units="ms">90.97</cn>
                        <apply>
                            <times/>
                            <apply>
                                <plus/>
                                <cn cellml:units="dimensionless">1</cn>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <plus/>
                                            <ci>V</ci>
                                            <cn cellml:units="mV">13.96</cn>
                                        </apply>
                                        <cn cellml:units="mV">45.38</cn>
                                    </apply>
                                </apply>
                            </apply>
                            <apply>
                                <plus/>
                                <cn cellml:units="dimensionless">1</cn>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <minus/>
                                            <apply>
                                                <minus/>
                                                <ci>V</ci>
                                            </apply>
                                            <cn cellml:units="mV">9.5</cn>
                                        </apply>
                                        <cn cellml:units="mV">3.39</cn>
                                    </apply>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
</model>