- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-10-18 15:02:26+13:00
- Desc:
- correction based on cross checking
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/701/rawfile/51ff74a5d6cec74225547f776376085466bd2985/Components/wholeCell.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="wholeCell" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="../cellLib/Components/units.cellml">
<units name="ms" units_ref="ms"/>
<units name="mV" units_ref="mV"/>
<units name="mM" units_ref="mM"/>
<units name="pA" units_ref="pA"/>
<units name="pF" units_ref="pF"/>
<units name="cmsq" units_ref="cmsq"/>
<units name="per_ms" units_ref="per_ms"/>
<units name="nS_per_pF" units_ref="nS_per_pF"/>
<units name="J_per_K_mol" units_ref="J_per_K_mol"/>
<units name="C_per_mmol" units_ref="C_per_mmol"/>
<units name="cm3" units_ref="cm3"/>
<units name="per_cmsq" units_ref="per_cmsq"/>
<units name="cm3_per_s" units_ref="cm3_per_s"/>
<units name="mM_per_ms" units_ref="mM_per_ms"/>
<units name="per_mMsq_ms" units_ref="per_mMsq_ms"/>
<units name="per_mM_ms" units_ref="per_mM_ms"/>
<units name="uN_per_um" units_ref="uN_per_um"/>
<units name="uN_ms_per_um" units_ref="uN_ms_per_um"/>
<units name="uN" units_ref="uN"/>
<units name="um" units_ref="um"/>
<units name="pA_per_pF" units_ref="pA_per_pF"/>
<units name="um_per_ms" units_ref="um_per_ms"/>
<units name="pF_per_cmsq" units_ref="pF_per_cmsq"/>
</import>
<units name="nmol2_per_J_s_cmsq">
<unit exponent="2" prefix="nano" units="mole"/>
<unit exponent="-1" units="joule"/>
<unit exponent="-1" units="second"/>
<unit exponent="-1" units="cmsq"/>
</units>
<import xlink:href="../cellLib/Components/CB4Yang.cellml">
<component component_ref="CB4Yang" name="CB4Yang"/>
</import>
<import xlink:href="CB4HM_Cai.cellml">
<component component_ref="CB4HM_Cai" name="CB4HM_Cai"/>
</import>
<!-- def import using "forceProduction.cellml" for
comp forceProduction using comp forceProduction;
enddef;-->
<import xlink:href="Cai.cellml">
<component component_ref="Cai" name="Cai"/>
</import>
<import xlink:href="Nai.cellml">
<component component_ref="Nai" name="Nai"/>
</import>
<import xlink:href="Ki.cellml">
<component component_ref="Ki" name="Ki"/>
</import>
<import xlink:href="Cli.cellml">
<component component_ref="Cli" name="Cli"/>
</import>
<import xlink:href="Car.cellml">
<component component_ref="Car" name="Car"/>
</import>
<import xlink:href="Cau.cellml">
<component component_ref="Cau" name="Cau"/>
</import>
<import xlink:href="ICaL.cellml">
<component component_ref="ICaL" name="ICaL"/>
</import>
<import xlink:href="ICaT.cellml">
<component component_ref="ICaT" name="ICaT"/>
</import>
<import xlink:href="INa.cellml">
<component component_ref="INa" name="INa"/>
</import>
<import xlink:href="IK1.cellml">
<component component_ref="IK1" name="IK1"/>
</import>
<import xlink:href="IK2.cellml">
<component component_ref="IK2" name="IK2"/>
</import>
<import xlink:href="IKA.cellml">
<component component_ref="IKA" name="IKA"/>
</import>
<import xlink:href="IKCa.cellml">
<component component_ref="IKCa" name="IKCa"/>
</import>
<import xlink:href="IKleak.cellml">
<component component_ref="IKleak" name="IKleak"/>
</import>
<import xlink:href="Ih.cellml">
<component component_ref="Ih" name="Ih"/>
</import>
<import xlink:href="ICl.cellml">
<component component_ref="ICl" name="ICl"/>
</import>
<import xlink:href="ICapump.cellml">
<component component_ref="ICapump" name="ICapump"/>
</import>
<import xlink:href="INaK.cellml">
<component component_ref="INaK" name="INaK"/>
</import>
<import xlink:href="INaCa.cellml">
<component component_ref="INaCa" name="INaCa"/>
</import>
<import xlink:href="INaKCl.cellml">
<component component_ref="INaKCl" name="INaKCl"/>
</import>
<import xlink:href="ISOCNa.cellml">
<component component_ref="ISOCNa" name="ISOCNa"/>
</import>
<import xlink:href="ISOCCa.cellml">
<component component_ref="ISOCCa" name="ISOCCa"/>
</import>
<import xlink:href="INSCa.cellml">
<component component_ref="INSCa" name="INSCa"/>
</import>
<import xlink:href="INSNa.cellml">
<component component_ref="INSNa" name="INSNa"/>
</import>
<import xlink:href="INSK.cellml">
<component component_ref="INSK" name="INSK"/>
</import>
<import xlink:href="INSleak.cellml">
<component component_ref="INSleak" name="INSleak"/>
</import>
<import xlink:href="Iup.cellml">
<component component_ref="Iup" name="Iup"/>
</import>
<import xlink:href="Itr.cellml">
<component component_ref="Itr" name="Itr"/>
</import>
<import xlink:href="Irel.cellml">
<component component_ref="Irel" name="Irel"/>
</import>
<component name="wholeCell">
<variable name="time" private_interface="out" public_interface="in" units="ms"/>
<variable name="I_stim" public_interface="in" units="pA_per_pF"/>
<variable name="V_init" public_interface="in" units="mV"/>
<variable name="R" private_interface="out" public_interface="in" units="J_per_K_mol"/>
<variable name="F" private_interface="out" public_interface="in" units="C_per_mmol"/>
<variable name="z_Na" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="z_Ca" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="z_K" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="z_Cl" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="T" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="Cm" private_interface="out" public_interface="in" units="pF_per_cmsq"/>
<variable name="Ac" private_interface="out" public_interface="in" units="cmsq"/>
<variable name="Vc" private_interface="out" public_interface="in" units="cm3"/>
<variable name="Cao" private_interface="out" public_interface="in" units="mM"/>
<variable name="Ko" private_interface="out" public_interface="in" units="mM"/>
<variable name="Nao" private_interface="out" public_interface="in" units="mM"/>
<variable name="Mgo" private_interface="out" public_interface="in" units="mM"/>
<variable name="Clo" private_interface="out" public_interface="in" units="mM"/>
<variable name="Q10Ca" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="Q10K" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="Q10Na" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="Q10h" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="Q10Cl" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="Q10KCa" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="T0CaL" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="T0CaT" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="T0K" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="T0Na" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="T0h" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="T0Cl" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="T0KCa" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="g_CaL" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="E_CaL" private_interface="out" public_interface="in" units="mV"/>
<variable name="K_mCaL" private_interface="out" public_interface="in" units="mM"/>
<variable name="tau_f1" private_interface="out" public_interface="in" units="ms"/>
<variable name="g_CaT" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="E_CaT" private_interface="out" public_interface="in" units="mV"/>
<variable name="g_Na" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="g_K1" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="g_K2" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="g_KA" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="N_BKCa" private_interface="out" public_interface="in" units="per_cmsq"/>
<variable name="C_est" private_interface="out" public_interface="in" units="pF"/>
<variable name="tau_pf" private_interface="out" public_interface="in" units="ms"/>
<variable name="tau_ps" private_interface="out" public_interface="in" units="ms"/>
<variable name="P_BKCa" private_interface="out" public_interface="in" units="cm3_per_s"/>
<variable name="g_Kleak" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="g_h" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="P_NaK" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="g_Cl" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="K_dCl" private_interface="out" public_interface="in" units="mM"/>
<variable name="tau_n" private_interface="out" public_interface="in" units="ms"/>
<variable name="J_pCa" private_interface="out" public_interface="in" units="mM_per_ms"/>
<variable name="K_mpCa" private_interface="out" public_interface="in" units="mM"/>
<variable name="hpCa" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="B_Ca" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="g_NaK" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="K_dK" private_interface="out" public_interface="in" units="mM"/>
<variable name="n_K" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="K_dNa" private_interface="out" public_interface="in" units="mM"/>
<variable name="n_Na" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="J_NaCamax" private_interface="out" public_interface="in" units="mM_per_ms"/>
<variable name="K_mAllo" private_interface="out" public_interface="in" units="mM"/>
<variable name="n_Allo" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="k_sat" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="gamma" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="K_mNai" private_interface="out" public_interface="in" units="mM"/>
<variable name="K_mCai" private_interface="out" public_interface="in" units="mM"/>
<variable name="K_mNao" private_interface="out" public_interface="in" units="mM"/>
<variable name="K_mCao" private_interface="out" public_interface="in" units="mM"/>
<variable name="L_NaKCl" private_interface="out" public_interface="in" units="nmol2_per_J_s_cmsq"/>
<variable name="R_NaKCl" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="g_SOCNa" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="g_SOCCa" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="K_mSOC" private_interface="out" public_interface="in" units="mM"/>
<variable name="g_NS" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="g_leak" private_interface="out" public_interface="in" units="nS_per_pF"/>
<variable name="K_dMg" private_interface="out" public_interface="in" units="mM"/>
<variable name="PNa_PCs" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="PK_PCs" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="PCa_PCs" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="P_Ca" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="P_Na" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="I_sus" public_interface="in" units="pA_per_pF"/>
<variable name="F_BCa" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="S_CM" private_interface="out" public_interface="in" units="mM"/>
<variable name="B_F" private_interface="out" public_interface="in" units="mM"/>
<variable name="K_d" private_interface="out" public_interface="in" units="mM"/>
<variable name="K_dB" private_interface="out" public_interface="in" units="mM"/>
<variable name="I_up0" private_interface="out" public_interface="in" units="pA"/>
<variable name="K_mup" private_interface="out" public_interface="in" units="mM"/>
<variable name="Vol_u" private_interface="out" public_interface="in" units="cm3"/>
<variable name="Vol_r" private_interface="out" public_interface="in" units="cm3"/>
<variable name="tau_tr" private_interface="out" public_interface="in" units="ms"/>
<variable name="tau_rel" private_interface="out" public_interface="in" units="ms"/>
<variable name="F_rel" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="CSQN" private_interface="out" public_interface="in" units="mM"/>
<variable name="K_CSQN" private_interface="out" public_interface="in" units="mM"/>
<variable name="R_leak" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="K_r1" private_interface="out" public_interface="in" units="per_mMsq_ms"/>
<variable name="K_r1minus" private_interface="out" public_interface="in" units="per_ms"/>
<variable name="K_r2" private_interface="out" public_interface="in" units="per_mM_ms"/>
<variable name="K_r2minus" private_interface="out" public_interface="in" units="per_ms"/>
<variable name="MLCK_max" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="K_MLCK" private_interface="out" public_interface="in" units="mM"/>
<variable name="K_CaMLCK" private_interface="out" public_interface="in" units="mM"/>
<variable name="C_ms" private_interface="out" public_interface="in" units="per_ms"/>
<variable name="p_M" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="n_M" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="K_2" private_interface="out" public_interface="in" units="per_ms"/>
<variable name="K_3" private_interface="out" public_interface="in" units="per_ms"/>
<variable name="K_4" private_interface="out" public_interface="in" units="per_ms"/>
<variable name="K_5" private_interface="out" public_interface="in" units="per_ms"/>
<variable name="K_7" private_interface="out" public_interface="in" units="per_ms"/>
<variable name="l_c" private_interface="out" public_interface="in" units="um"/>
<variable name="l_c0" private_interface="out" public_interface="in" units="um"/>
<variable name="l_s0" private_interface="out" public_interface="in" units="um"/>
<variable name="l_opt" private_interface="out" public_interface="in" units="um"/>
<variable name="k_x1" private_interface="out" public_interface="in" units="uN_per_um"/>
<variable name="k_x2" private_interface="out" public_interface="in" units="uN_per_um"/>
<variable name="k_s" private_interface="out" public_interface="in" units="uN"/>
<variable name="k_p" private_interface="out" public_interface="in" units="uN"/>
<variable name="v_x" private_interface="out" public_interface="in" units="um_per_ms"/>
<variable name="f_AMp" private_interface="out" public_interface="in" units="uN_ms_per_um"/>
<variable name="f_AM" private_interface="out" public_interface="in" units="uN_ms_per_um"/>
<variable name="mu_s" private_interface="out" public_interface="in" units="uN_ms_per_um"/>
<variable name="alpha_s" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="alpha_p" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="beta" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="Cai_init" private_interface="out" public_interface="in" units="mM"/>
<variable name="Nai_init" private_interface="out" public_interface="in" units="mM"/>
<variable name="Ki_init" private_interface="out" public_interface="in" units="mM"/>
<variable name="Cli_init" private_interface="out" public_interface="in" units="mM"/>
<variable name="Cau_init" private_interface="out" public_interface="in" units="mM"/>
<variable name="Car_init" private_interface="out" public_interface="in" units="mM"/>
<variable name="d_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="f1_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="f2_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="b_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="g_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="m_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="h_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="q_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="r1_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="r2_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="p_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="ps_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="pf_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="k1_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="k2_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="s_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="x_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="y_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="c1_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="c2_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="n_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="ls_init" private_interface="out" public_interface="in" units="um"/>
<variable name="la_init" private_interface="out" public_interface="in" units="um"/>
<variable name="lx_init" private_interface="out" public_interface="in" units="um"/>
<variable name="M_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="Mp_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="AM_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="AMp_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="R00_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="R10_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="R01_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="R11_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="ICa_tot" private_interface="out" public_interface="out" units="pA_per_pF"/>
<variable name="INa_tot" private_interface="out" public_interface="out" units="pA_per_pF"/>
<variable name="IK_tot" private_interface="out" public_interface="out" units="pA_per_pF"/>
<variable name="ICl_tot" private_interface="out" public_interface="out" units="pA_per_pF"/>
<variable name="I_tot" public_interface="out" units="pA_per_pF"/>
<variable name="I_CaL" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_CaL" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_CaT" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_CaT" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_Na" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_Nai" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_K1" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_K1" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_K2" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_K2" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_KA" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_KA" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_KCa" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_Kleak" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_Kleak" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_h" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_h" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_Cl" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_Cl" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_Capump" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_NaK" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_NaCa" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_NaKCl" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_NaKCl_Na" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_NaKCl_K" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_SOCNa" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_SOCCa" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="I_NSCa" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_NSCa" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_NSNa" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_NSNa" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_NSK" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_NSK" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_NSleak" private_interface="in" public_interface="out" units="pA_per_pF"/>
<variable name="P_NSleak" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="I_up" private_interface="in" public_interface="out" units="pA"/>
<variable name="I_tr" private_interface="in" public_interface="out" units="pA"/>
<variable name="I_rel" private_interface="in" public_interface="out" units="pA"/>
<variable name="b_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="g_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_b" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_g" private_interface="in" public_interface="out" units="ms"/>
<variable name="d_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="f_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_d" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_f2" private_interface="in" public_interface="out" units="ms"/>
<variable name="m_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="h_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_m" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_h" private_interface="in" public_interface="out" units="ms"/>
<variable name="q_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="r_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_q" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_r1" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_r2" private_interface="in" public_interface="out" units="ms"/>
<variable name="p_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="k_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_p" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_k1" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_k2" private_interface="in" public_interface="out" units="ms"/>
<variable name="s_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="x_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_s" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_x" private_interface="in" public_interface="out" units="ms"/>
<variable name="y_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_y" private_interface="in" public_interface="out" units="ms"/>
<variable name="n_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="c_inf" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_c1" private_interface="in" public_interface="out" units="ms"/>
<variable name="tau_c2" private_interface="in" public_interface="out" units="ms"/>
<variable name="stress" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="phosphorylation" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="M" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="Mp" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="AM" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="AMp" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="R_00" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="R_10" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="R_01" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="R_11" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="Cai" private_interface="in" public_interface="out" units="mM"/>
<variable name="Ki" private_interface="in" public_interface="out" units="mM"/>
<variable name="Nai" private_interface="in" public_interface="out" units="mM"/>
<variable name="Cli" private_interface="in" public_interface="out" units="mM"/>
<variable name="Cau" private_interface="in" public_interface="out" units="mM"/>
<variable name="Car" private_interface="in" public_interface="out" units="mM"/>
<variable initial_value="V_init" name="V" private_interface="out" public_interface="out" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICa_tot</ci>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<ci>I_CaL</ci>
<ci>I_CaT</ci>
<ci>I_NSCa</ci>
<ci>I_SOCCa</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>I_NaCa</ci>
</apply>
</apply>
<ci>I_Capump</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>I_up</ci>
<ci>I_rel</ci>
</apply>
<apply>
<times/>
<ci>Ac</ci>
<ci>Cm</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INa_tot</ci>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<ci>I_Na</ci>
<ci>I_NSCa</ci>
<ci>I_SOCNa</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>I_NaK</ci>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>I_NaCa</ci>
</apply>
<apply>
<times/>
<ci>P_Na</ci>
<ci>I_h</ci>
</apply>
<ci>I_NaKCl_Na</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>IK_tot</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<ci>I_K1</ci>
<ci>I_K2</ci>
<ci>I_KA</ci>
<ci>I_KCa</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>I_NSK</ci>
</apply>
</apply>
<ci>I_Kleak</ci>
<ci>I_NaKCl</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>I_NaK</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ICl_tot</ci>
<apply>
<plus/>
<ci>I_Cl</ci>
<ci>I_NaKCl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>I_tot</ci>
<apply>
<plus/>
<ci>I_h</ci>
<ci>I_CaL</ci>
<ci>I_CaT</ci>
<ci>I_Na</ci>
<ci>I_K1</ci>
<ci>I_K2</ci>
<ci>I_KA</ci>
<ci>I_KCa</ci>
<ci>I_NSCa</ci>
<ci>I_NSNa</ci>
<ci>I_NSK</ci>
<ci>I_NSleak</ci>
<ci>I_Cl</ci>
<ci>I_Capump</ci>
<ci>I_NaK</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>I_NaCa</ci>
</apply>
<ci>I_sus</ci>
<ci>I_SOCNa</ci>
<ci>I_SOCCa</ci>
<ci>I_Kleak</ci>
<ci>I_NaKCl</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<ci>I_tot</ci>
</apply>
<ci>I_stim</ci>
</apply>
</apply>
</math>
</component>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="wholeCell">
<component_ref component="ICaL"/>
<component_ref component="ICaT"/>
<component_ref component="INa"/>
<component_ref component="IK1"/>
<component_ref component="IK2"/>
<component_ref component="IKA"/>
<component_ref component="IKCa"/>
<component_ref component="IKleak"/>
<component_ref component="Ih"/>
<component_ref component="ICl"/>
<component_ref component="ICapump"/>
<component_ref component="INaK"/>
<component_ref component="INaCa"/>
<component_ref component="INaKCl"/>
<component_ref component="ISOCNa"/>
<component_ref component="ISOCCa"/>
<component_ref component="INSCa"/>
<component_ref component="INSNa"/>
<component_ref component="INSK"/>
<component_ref component="INSleak"/>
<component_ref component="Iup"/>
<component_ref component="Itr"/>
<component_ref component="Irel"/>
<component_ref component="CB4Yang"/>
<component_ref component="CB4HM_Cai"/>
<!-- comp forceProduction;-->
<component_ref component="Cai"/>
<component_ref component="Nai"/>
<component_ref component="Ki"/>
<component_ref component="Cli"/>
<component_ref component="Cau"/>
<component_ref component="Car"/>
</component_ref>
</group>
<connection>
<map_components component_1="wholeCell" component_2="CB4Yang"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="R00_init" variable_2="R00_init"/>
<map_variables variable_1="R10_init" variable_2="R10_init"/>
<map_variables variable_1="R01_init" variable_2="R01_init"/>
<map_variables variable_1="R11_init" variable_2="R11_init"/>
<map_variables variable_1="K_r1" variable_2="K_r1"/>
<map_variables variable_1="K_r1minus" variable_2="K_r1minus"/>
<map_variables variable_1="K_r2" variable_2="K_r2"/>
<map_variables variable_1="K_r2minus" variable_2="K_r2minus"/>
<map_variables variable_1="R_00" variable_2="R_00"/>
<map_variables variable_1="R_10" variable_2="R_10"/>
<map_variables variable_1="R_01" variable_2="R_01"/>
<map_variables variable_1="R_11" variable_2="R_11"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="CB4HM_Cai"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="C_ms" variable_2="C_ms"/>
<map_variables variable_1="M_init" variable_2="M_init"/>
<map_variables variable_1="Mp_init" variable_2="Mp_init"/>
<map_variables variable_1="AM_init" variable_2="AM_init"/>
<map_variables variable_1="AMp_init" variable_2="AMp_init"/>
<map_variables variable_1="MLCK_max" variable_2="MLCK_max"/>
<map_variables variable_1="K_MLCK" variable_2="K_MLCK"/>
<map_variables variable_1="K_CaMLCK" variable_2="K_CaMLCK"/>
<map_variables variable_1="p_M" variable_2="p_M"/>
<map_variables variable_1="n_M" variable_2="n_M"/>
<map_variables variable_1="K_2" variable_2="K_2"/>
<map_variables variable_1="K_3" variable_2="K_3"/>
<map_variables variable_1="K_4" variable_2="K_4"/>
<map_variables variable_1="K_5" variable_2="K_5"/>
<map_variables variable_1="K_7" variable_2="K_7"/>
<map_variables variable_1="stress" variable_2="stress"/>
<map_variables variable_1="phosphorylation" variable_2="phosphorylation"/>
<map_variables variable_1="AMp" variable_2="AMp"/>
<map_variables variable_1="AM" variable_2="AM"/>
<map_variables variable_1="Mp" variable_2="Mp"/>
<map_variables variable_1="M" variable_2="M"/>
</connection>
<connection>
<map_components component_1="CB4HM_Cai" component_2="Cai"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="CB4Yang" component_2="Cai"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Cai"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Cai_init" variable_2="Cai_init"/>
<map_variables variable_1="ICa_tot" variable_2="ICa_tot"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="z_Ca" variable_2="z_Ca"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vc" variable_2="Vc"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
<map_variables variable_1="F_BCa" variable_2="F_BCa"/>
<map_variables variable_1="S_CM" variable_2="S_CM"/>
<map_variables variable_1="B_F" variable_2="B_F"/>
<map_variables variable_1="K_d" variable_2="K_d"/>
<map_variables variable_1="K_dB" variable_2="K_dB"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Nai"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Nai_init" variable_2="Nai_init"/>
<map_variables variable_1="INa_tot" variable_2="INa_tot"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="z_Na" variable_2="z_Na"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vc" variable_2="Vc"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Ki"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Ki_init" variable_2="Ki_init"/>
<map_variables variable_1="IK_tot" variable_2="IK_tot"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="z_K" variable_2="z_K"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vc" variable_2="Vc"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Cli"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Cli_init" variable_2="Cli_init"/>
<map_variables variable_1="ICl_tot" variable_2="ICl_tot"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="z_Cl" variable_2="z_Cl"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vc" variable_2="Vc"/>
<map_variables variable_1="Cli" variable_2="Cli"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Cau"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Cau_init" variable_2="Cau_init"/>
<map_variables variable_1="z_Ca" variable_2="z_Ca"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vol_u" variable_2="Vol_u"/>
<map_variables variable_1="Cau" variable_2="Cau"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Car"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Car_init" variable_2="Car_init"/>
<map_variables variable_1="CSQN" variable_2="CSQN"/>
<map_variables variable_1="K_CSQN" variable_2="K_CSQN"/>
<map_variables variable_1="z_Ca" variable_2="z_Ca"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vol_r" variable_2="Vol_r"/>
<map_variables variable_1="Car" variable_2="Car"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="ICaL"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_CaL" variable_2="I_CaL"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="E_CaL" variable_2="E_CaL"/>
<map_variables variable_1="g_CaL" variable_2="g_CaL"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0CaL" variable_2="T0CaL"/>
<map_variables variable_1="Q10Ca" variable_2="Q10Ca"/>
<map_variables variable_1="K_mCaL" variable_2="K_mCaL"/>
<map_variables variable_1="tau_f1" variable_2="tau_f1"/>
<map_variables variable_1="d_init" variable_2="d_init"/>
<map_variables variable_1="f1_init" variable_2="f1_init"/>
<map_variables variable_1="f2_init" variable_2="f2_init"/>
<map_variables variable_1="P_CaL" variable_2="P_CaL"/>
<map_variables variable_1="d_inf" variable_2="d_inf"/>
<map_variables variable_1="f_inf" variable_2="f_inf"/>
<map_variables variable_1="tau_d" variable_2="tau_d"/>
<map_variables variable_1="tau_f2" variable_2="tau_f2"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="ICaL"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="ICaT"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_CaT" variable_2="I_CaT"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="E_CaT" variable_2="E_CaT"/>
<map_variables variable_1="g_CaT" variable_2="g_CaT"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0CaT" variable_2="T0CaT"/>
<map_variables variable_1="Q10Ca" variable_2="Q10Ca"/>
<map_variables variable_1="b_init" variable_2="b_init"/>
<map_variables variable_1="g_init" variable_2="g_init"/>
<map_variables variable_1="P_CaT" variable_2="P_CaT"/>
<map_variables variable_1="b_inf" variable_2="b_inf"/>
<map_variables variable_1="g_inf" variable_2="g_inf"/>
<map_variables variable_1="tau_b" variable_2="tau_b"/>
<map_variables variable_1="tau_g" variable_2="tau_g"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="INa"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_Na" variable_2="I_Na"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_Na" variable_2="g_Na"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0Na" variable_2="T0Na"/>
<map_variables variable_1="Q10Na" variable_2="Q10Na"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="m_init" variable_2="m_init"/>
<map_variables variable_1="h_init" variable_2="h_init"/>
<map_variables variable_1="P_Nai" variable_2="P_Na"/>
<map_variables variable_1="m_inf" variable_2="m_inf"/>
<map_variables variable_1="h_inf" variable_2="h_inf"/>
<map_variables variable_1="tau_m" variable_2="tau_m"/>
<map_variables variable_1="tau_h" variable_2="tau_h"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INa"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="IK1"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_K1" variable_2="I_K1"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_K1" variable_2="g_K1"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0K" variable_2="T0K"/>
<map_variables variable_1="Q10K" variable_2="Q10K"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="q_init" variable_2="q_init"/>
<map_variables variable_1="r1_init" variable_2="r1_init"/>
<map_variables variable_1="r2_init" variable_2="r2_init"/>
<map_variables variable_1="P_K1" variable_2="P_K1"/>
<map_variables variable_1="q_inf" variable_2="q_inf"/>
<map_variables variable_1="r_inf" variable_2="r_inf"/>
<map_variables variable_1="tau_q" variable_2="tau_q"/>
<map_variables variable_1="tau_r1" variable_2="tau_r1"/>
<map_variables variable_1="tau_r2" variable_2="tau_r2"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="IK1"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="IK2"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_K2" variable_2="I_K2"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_K2" variable_2="g_K2"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0K" variable_2="T0K"/>
<map_variables variable_1="Q10K" variable_2="Q10K"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="p_init" variable_2="p_init"/>
<map_variables variable_1="k1_init" variable_2="k1_init"/>
<map_variables variable_1="k2_init" variable_2="k2_init"/>
<map_variables variable_1="P_K2" variable_2="P_K2"/>
<map_variables variable_1="p_inf" variable_2="p_inf"/>
<map_variables variable_1="k_inf" variable_2="k_inf"/>
<map_variables variable_1="tau_p" variable_2="tau_p"/>
<map_variables variable_1="tau_k1" variable_2="tau_k1"/>
<map_variables variable_1="tau_k2" variable_2="tau_k2"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="IK2"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="IKA"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_KA" variable_2="I_KA"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_KA" variable_2="g_KA"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0K" variable_2="T0K"/>
<map_variables variable_1="Q10K" variable_2="Q10K"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="s_init" variable_2="s_init"/>
<map_variables variable_1="x_init" variable_2="x_init"/>
<map_variables variable_1="P_KA" variable_2="P_KA"/>
<map_variables variable_1="s_inf" variable_2="s_inf"/>
<map_variables variable_1="x_inf" variable_2="x_inf"/>
<map_variables variable_1="tau_s" variable_2="tau_s"/>
<map_variables variable_1="tau_x" variable_2="tau_x"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="IKA"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="IKCa"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_KCa" variable_2="I_KCa"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="P_BKCa" variable_2="P_BKCa"/>
<map_variables variable_1="N_BKCa" variable_2="N_BKCa"/>
<map_variables variable_1="C_est" variable_2="C_est"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0KCa" variable_2="T0KCa"/>
<map_variables variable_1="Q10KCa" variable_2="Q10KCa"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="pf_init" variable_2="pf_init"/>
<map_variables variable_1="tau_pf" variable_2="tau_pf"/>
<map_variables variable_1="ps_init" variable_2="ps_init"/>
<map_variables variable_1="tau_ps" variable_2="tau_ps"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="IKCa"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="IKCa"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="IKleak"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_Kleak" variable_2="I_Kleak"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_Kleak" variable_2="g_Kleak"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="P_Kleak" variable_2="P_Kleak"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="IKleak"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Ih"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_h" variable_2="I_h"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_h" variable_2="g_h"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0h" variable_2="T0h"/>
<map_variables variable_1="Q10h" variable_2="Q10h"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="P_NaK" variable_2="P_NaK"/>
<map_variables variable_1="y_init" variable_2="y_init"/>
<map_variables variable_1="P_h" variable_2="P_h"/>
<map_variables variable_1="y_inf" variable_2="y_inf"/>
<map_variables variable_1="tau_y" variable_2="tau_y"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="Ih"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="Ih"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="ICl"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="I_Cl" variable_2="I_Cl"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_Cl" variable_2="g_Cl"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0Cl" variable_2="T0Cl"/>
<map_variables variable_1="Q10Cl" variable_2="Q10Cl"/>
<map_variables variable_1="K_dCl" variable_2="K_dCl"/>
<map_variables variable_1="tau_n" variable_2="tau_n"/>
<map_variables variable_1="n_init" variable_2="n_init"/>
<map_variables variable_1="c1_init" variable_2="c1_init"/>
<map_variables variable_1="c2_init" variable_2="c2_init"/>
<map_variables variable_1="P_Cl" variable_2="P_Cl"/>
<map_variables variable_1="n_inf" variable_2="n_inf"/>
<map_variables variable_1="c_inf" variable_2="c_inf"/>
<map_variables variable_1="tau_c1" variable_2="tau_c1"/>
<map_variables variable_1="tau_c2" variable_2="tau_c2"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="ICl"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="ICapump"/>
<map_variables variable_1="I_Capump" variable_2="I_Capump"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="z_Ca" variable_2="z_Ca"/>
<map_variables variable_1="B_Ca" variable_2="B_Ca"/>
<map_variables variable_1="J_pCa" variable_2="J_pCa"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vc" variable_2="Vc"/>
<map_variables variable_1="K_mpCa" variable_2="K_mpCa"/>
<map_variables variable_1="hpCa" variable_2="hpCa"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="ICapump"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="INaK"/>
<map_variables variable_1="I_NaK" variable_2="I_NaK"/>
<map_variables variable_1="g_NaK" variable_2="g_NaK"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="K_dNa" variable_2="K_dNa"/>
<map_variables variable_1="n_Na" variable_2="n_Na"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="K_dK" variable_2="K_dK"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="n_K" variable_2="n_K"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INaK"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="INaCa"/>
<map_variables variable_1="I_NaCa" variable_2="I_NaCa"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="z_Ca" variable_2="z_Ca"/>
<map_variables variable_1="Vc" variable_2="Vc"/>
<map_variables variable_1="k_sat" variable_2="k_sat"/>
<map_variables variable_1="gamma" variable_2="gamma"/>
<map_variables variable_1="J_NaCamax" variable_2="J_NaCamax"/>
<map_variables variable_1="K_mNai" variable_2="K_mNai"/>
<map_variables variable_1="K_mCai" variable_2="K_mCai"/>
<map_variables variable_1="K_mNao" variable_2="K_mNao"/>
<map_variables variable_1="K_mCao" variable_2="K_mCao"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
<map_variables variable_1="K_mAllo" variable_2="K_mAllo"/>
<map_variables variable_1="n_Allo" variable_2="n_Allo"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="INaCa"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INaCa"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="INaKCl"/>
<map_variables variable_1="I_NaKCl" variable_2="I_NaKCl"/>
<map_variables variable_1="I_NaKCl_Na" variable_2="I_NaKCl_Na"/>
<map_variables variable_1="I_NaKCl_K" variable_2="I_NaKCl_K"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="z_Cl" variable_2="z_Cl"/>
<map_variables variable_1="R_NaKCl" variable_2="R_NaKCl"/>
<map_variables variable_1="L_NaKCl" variable_2="L_NaKCl"/>
<map_variables variable_1="C_est" variable_2="C_est"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="Clo" variable_2="Clo"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INaKCl"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="INaKCl"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="Cli" component_2="INaKCl"/>
<map_variables variable_1="Cli" variable_2="Cli"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="ISOCNa"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_SOCNa" variable_2="g_SOCNa"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="K_mSOC" variable_2="K_mSOC"/>
<map_variables variable_1="I_SOCNa" variable_2="I_SOCNa"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="ISOCNa"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="ISOCNa"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Cau" component_2="ISOCNa"/>
<map_variables variable_1="Cau" variable_2="Cau"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="ISOCCa"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_SOCCa" variable_2="g_SOCCa"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
<map_variables variable_1="K_mSOC" variable_2="K_mSOC"/>
<map_variables variable_1="I_SOCCa" variable_2="I_SOCCa"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="ISOCCa"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Cau" component_2="ISOCCa"/>
<map_variables variable_1="Cau" variable_2="Cau"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="INSCa"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_NS" variable_2="g_NS"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="PCa_PCs" variable_2="PCa_PCs"/>
<map_variables variable_1="PNa_PCs" variable_2="PNa_PCs"/>
<map_variables variable_1="PK_PCs" variable_2="PK_PCs"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="Mgo" variable_2="Mgo"/>
<map_variables variable_1="K_dMg" variable_2="K_dMg"/>
<map_variables variable_1="P_NSCa" variable_2="P_NSCa"/>
<map_variables variable_1="I_NSCa" variable_2="I_NSCa"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="INSCa"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INSCa"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="INSCa"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="INSNa"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_NS" variable_2="g_NS"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="PCa_PCs" variable_2="PCa_PCs"/>
<map_variables variable_1="PNa_PCs" variable_2="PNa_PCs"/>
<map_variables variable_1="PK_PCs" variable_2="PK_PCs"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="Mgo" variable_2="Mgo"/>
<map_variables variable_1="K_dMg" variable_2="K_dMg"/>
<map_variables variable_1="P_NSNa" variable_2="P_NSNa"/>
<map_variables variable_1="I_NSNa" variable_2="I_NSNa"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="INSNa"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INSNa"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="INSNa"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="INSK"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_NS" variable_2="g_NS"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="PCa_PCs" variable_2="PCa_PCs"/>
<map_variables variable_1="PNa_PCs" variable_2="PNa_PCs"/>
<map_variables variable_1="PK_PCs" variable_2="PK_PCs"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="Mgo" variable_2="Mgo"/>
<map_variables variable_1="K_dMg" variable_2="K_dMg"/>
<map_variables variable_1="P_NSK" variable_2="P_NSK"/>
<map_variables variable_1="I_NSK" variable_2="I_NSK"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="INSK"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INSK"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="INSK"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="INSleak"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_leak" variable_2="g_leak"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
<map_variables variable_1="Ac" variable_2="Ac"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="PCa_PCs" variable_2="PCa_PCs"/>
<map_variables variable_1="PNa_PCs" variable_2="PNa_PCs"/>
<map_variables variable_1="PK_PCs" variable_2="PK_PCs"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
<map_variables variable_1="Mgo" variable_2="Mgo"/>
<map_variables variable_1="K_dMg" variable_2="K_dMg"/>
<map_variables variable_1="P_NSleak" variable_2="P_NSleak"/>
<map_variables variable_1="I_NSleak" variable_2="I_NSleak"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="INSleak"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INSleak"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="INSleak"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Iup"/>
<map_variables variable_1="I_up0" variable_2="I_up0"/>
<map_variables variable_1="K_mup" variable_2="K_mup"/>
<map_variables variable_1="I_up" variable_2="I_up"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Itr"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vol_u" variable_2="Vol_u"/>
<map_variables variable_1="z_Ca" variable_2="z_Ca"/>
<map_variables variable_1="tau_tr" variable_2="tau_tr"/>
<map_variables variable_1="I_tr" variable_2="I_tr"/>
</connection>
<connection>
<map_components component_1="wholeCell" component_2="Irel"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Vol_r" variable_2="Vol_r"/>
<map_variables variable_1="z_Ca" variable_2="z_Ca"/>
<map_variables variable_1="F_rel" variable_2="F_rel"/>
<map_variables variable_1="R_leak" variable_2="R_leak"/>
<map_variables variable_1="tau_rel" variable_2="tau_rel"/>
<map_variables variable_1="I_rel" variable_2="I_rel"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="Iup"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Car" component_2="Irel"/>
<map_variables variable_1="Car" variable_2="Car"/>
<map_variables variable_1="I_rel" variable_2="I_rel"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="Irel"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Iup" component_2="Cau"/>
<map_variables variable_1="I_up" variable_2="I_up"/>
</connection>
<connection>
<map_components component_1="Itr" component_2="Cau"/>
<map_variables variable_1="I_tr" variable_2="I_tr"/>
<map_variables variable_1="Cau" variable_2="Cau"/>
</connection>
<connection>
<map_components component_1="Itr" component_2="Car"/>
<map_variables variable_1="I_tr" variable_2="I_tr"/>
<map_variables variable_1="Car" variable_2="Car"/>
</connection>
<connection>
<map_components component_1="CB4Yang" component_2="Irel"/>
<map_variables variable_1="R_10" variable_2="R_10"/>
</connection>
</model>
