- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-09-07 14:37:10+12:00
- Desc:
- Add ICaT.cellml
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/701/rawfile/333aba2c72fcb7066bc3ee3d40c00195bf99813d/Components/ICaT.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="ICaT" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units.cellml">
<units name="mM" units_ref="mM"/>
<units name="ms" units_ref="ms"/>
<units name="pA" units_ref="pA"/>
<units name="mV" units_ref="mV"/>
<units name="nS" units_ref="nS"/>
<units name="J_per_K_mol" units_ref="J_per_K_mol"/>
<units name="C_per_mmol" units_ref="C_per_mmol"/>
</import>
<import xlink:href="Ionic_currents.cellml">
<component component_ref="Ionic_currents" name="Ionic_currents"/>
</import>
<import xlink:href="E_Nernst.cellml">
<component component_ref="E_Ca" name="E_Ca"/>
</import>
<import xlink:href="gating_kinetics.cellml">
<component component_ref="gating_kinetics" name="d_gate"/>
</import>
<import xlink:href="gating_kinetics.cellml">
<component component_ref="gating_kinetics" name="f_gate"/>
</import>
<import xlink:href="ICaT_gating_inf.cellml">
<component component_ref="d_inf" name="d_inf"/>
<component component_ref="f_inf" name="f_inf"/>
</import>
<import xlink:href="time_constant_f.cellml">
<component component_ref="tau_f" name="tau_f"/>
</import>
<component name="ICaT">
<variable name="time" private_interface="out" public_interface="in" units="ms"/>
<variable name="I_CaT" private_interface="in" public_interface="out" units="pA"/>
<variable name="V" private_interface="out" public_interface="in" units="mV"/>
<variable name="g_CaT" private_interface="out" public_interface="in" units="nS"/>
<variable name="T" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="T0CaT" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="Q10Ca" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="Cao" private_interface="out" public_interface="in" units="mM"/>
<variable name="Cai" private_interface="out" public_interface="in" units="mM"/>
<variable name="d_CaT_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="d_CaT" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="f_CaT_init" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="f_CaT" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="tau_dCaT" private_interface="out" public_interface="in" units="ms"/>
<variable name="P_CaT" private_interface="out" public_interface="out" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>P_CaT</ci>
<apply>
<times/>
<ci>d_CaT</ci>
<ci>f_CaT</ci>
</apply>
</apply>
</math>
</component>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="ICaT">
<component_ref component="Ionic_currents"/>
<component_ref component="E_Ca"/>
<component_ref component="d_gate"/>
<component_ref component="f_gate"/>
<component_ref component="d_inf"/>
<component_ref component="f_inf"/>
<component_ref component="tau_f"/>
</component_ref>
</group>
<connection>
<map_components component_1="ICaT" component_2="d_inf"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="f_inf"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="tau_f"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="d_gate"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Q10Ca" variable_2="Q10"/>
<map_variables variable_1="T0CaT" variable_2="T0"/>
<map_variables variable_1="d_CaT_init" variable_2="X_initial"/>
<map_variables variable_1="d_CaT" variable_2="X"/>
<map_variables variable_1="tau_dCaT" variable_2="tau_X"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="f_gate"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Q10Ca" variable_2="Q10"/>
<map_variables variable_1="T0CaT" variable_2="T0"/>
<map_variables variable_1="f_CaT_init" variable_2="X_initial"/>
<map_variables variable_1="f_CaT" variable_2="X"/>
</connection>
<connection>
<map_components component_1="d_inf" component_2="d_gate"/>
<map_variables variable_1="X_inf" variable_2="X_inf"/>
</connection>
<connection>
<map_components component_1="f_inf" component_2="f_gate"/>
<map_variables variable_1="X_inf" variable_2="X_inf"/>
</connection>
<connection>
<map_components component_1="tau_f" component_2="f_gate"/>
<map_variables variable_1="tau" variable_2="tau_X"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="Ionic_currents"/>
<map_variables variable_1="I_CaT" variable_2="I"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_CaT" variable_2="g_max"/>
<map_variables variable_1="P_CaT" variable_2="PO"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="E_Ca"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
</connection>
<connection>
<map_components component_1="E_Ca" component_2="Ionic_currents"/>
<map_variables variable_1="E_Ca" variable_2="E"/>
</connection>
</model>
