Location: Model of excitation-contraction in uterine myocytes from a pregnant rat @ 1451a14f3fbe / Components / ISOCCa.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2022-01-20 12:46:30+13:00
Desc:
revert the scaling in the currents
Permanent Source URI:
https://models.physiomeproject.org/workspace/701/rawfile/1451a14f3fbe8fd7aacd0d0a73d87cec591b26de/Components/ISOCCa.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="ISOCCa" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="../cellLib/Components/units.cellml">
        <units name="pA_per_pF" units_ref="pA_per_pF"/>
        <units name="pA" units_ref="pA"/>
        <units name="nS" units_ref="nS"/>
        <units name="mV" units_ref="mV"/>
        <units name="mM" units_ref="mM"/>
        <units name="nS_per_pF" units_ref="nS_per_pF"/>
        <units name="pF" units_ref="pF"/>
    </import>
    <import xlink:href="../cellLib/Components/Ionic_currents.cellml">
        <component component_ref="Ionic_currents" name="I_SOCCa_pA"/>
    </import>
    <import xlink:href="../cellLib/Components/Hillfcn.cellml">
        <component component_ref="Hillfcn" name="P_SOC"/>
    </import>
    <component name="ISOCCa">
        <variable name="V" private_interface="out" public_interface="in" units="mV"/>
        <variable name="g_SOCCa" private_interface="out" public_interface="in" units="nS_per_pF"/>
        <variable name="E_Ca" private_interface="out" public_interface="in" units="mV"/>
        <variable name="C_est" private_interface="out" public_interface="in" units="pF"/>
        <variable name="Cai" public_interface="in" units="mM"/>
        <variable name="K_mSOC" public_interface="in" units="mM"/>
        <variable name="x_h" private_interface="out" units="dimensionless"/>
        <variable initial_value="1" name="n_h" private_interface="out" units="dimensionless"/>
        <variable name="I_SOCCa" private_interface="in" public_interface="out" units="pA_per_pF"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>x_h</ci>
                <apply>
                    <divide/>
                    <ci>Cai</ci>
                    <ci>K_mSOC</ci>
                </apply>
            </apply>
        </math>
    </component>
    <connection>
        <map_components component_1="ISOCCa" component_2="P_SOC"/>
        <map_variables variable_1="x_h" variable_2="x"/>
        <map_variables variable_1="n_h" variable_2="n"/>
    </connection>
    <component name="convert_I_SOCCa_pA">
        <variable name="I_SOCCa" public_interface="out" units="pA_per_pF"/>
        <variable name="g_SOCCa_ns" public_interface="out" units="nS"/>
        <variable name="I_SOCCa_pA" public_interface="in" units="pA"/>
        <variable name="g_SOCCa" public_interface="in" units="nS_per_pF"/>
        <variable name="C_est" public_interface="in" units="pF"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>g_SOCCa_ns</ci>
                <apply>
                    <times/>
                    <ci>g_SOCCa</ci>
                    <ci>C_est</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>I_SOCCa</ci>
                <apply>
                    <divide/>
                    <ci>I_SOCCa_pA</ci>
                    <ci>C_est</ci>
                </apply>
            </apply>
        </math>
    </component>
    <group>
        <relationship_ref relationship="encapsulation"/>
        <component_ref component="ISOCCa">
            <component_ref component="I_SOCCa_pA"/>
            <component_ref component="convert_I_SOCCa_pA"/>
            <component_ref component="P_SOC"/>
        </component_ref>
    </group>
    <connection>
        <map_components component_1="ISOCCa" component_2="I_SOCCa_pA"/>
        <map_variables variable_1="V" variable_2="V"/>
        <map_variables variable_1="E_Ca" variable_2="E"/>
    </connection>
    <connection>
        <map_components component_1="P_SOC" component_2="I_SOCCa_pA"/>
        <map_variables variable_1="H" variable_2="PO"/>
    </connection>
    <connection>
        <map_components component_1="convert_I_SOCCa_pA" component_2="I_SOCCa_pA"/>
        <map_variables variable_1="I_SOCCa_pA" variable_2="I"/>
        <map_variables variable_1="g_SOCCa_ns" variable_2="g_max"/>
    </connection>
    <connection>
        <map_components component_1="ISOCCa" component_2="convert_I_SOCCa_pA"/>
        <map_variables variable_1="I_SOCCa" variable_2="I_SOCCa"/>
        <map_variables variable_1="g_SOCCa" variable_2="g_SOCCa"/>
        <map_variables variable_1="C_est" variable_2="C_est"/>
    </connection>
</model>