- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-09-30 13:03:10+13:00
- Desc:
- Update the initial Cai values based on Limor's confirmation;
Update the documentation.
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/6bb/rawfile/40b87e3eeb0fde9f8304ebba3c48c3058cd7fc50/Doc/Vm_stim_experiment.rst
Membrane potential simulation experiment
----------------------------------------
In the `Membrane potential simulation experiment <Experiments/Vm_stim_experiment.cellml/view>`_, the `Excitation-contraction component <../Components/EC_uSMC.cellml>`_ is configured and parameterised. The component ``Vm`` is defined to simulate a recorded human plateau potential.
You can bypass the parameters in the component ``model_parameters`` and ``initial_conditions`` and define your own parameters.
The simulation experiment can be obtained by loading the `corresponding SED-ML document <../Simulation/Vm_stim_experiment.sedml>`_ into OpenCOR and executing the simulation.
Simulation of :math:`Ca_i^{2+}` Control and Stress Production
-------------------------------------------------------------
Figure [#]_ shows the simulation of changes in :math:`Ca_i^{2+}` and stress in response to the plateau potential :math:`V_m`.
.. [#]
.. figure:: ../Simulation/simFig12.png
:width: 75%
:align: center
:alt: simFig12
