Location: Model of Human Jejunal Smooth Muscle Cell Electrophysiology @ 73deb9635bb1 / Doc / Periodic_stimulation.rst

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2021-06-09 16:00:05+12:00
Desc:
Add SA experiment and more documentation, figures
Permanent Source URI:
https://models.physiomeproject.org/workspace/692/rawfile/73deb9635bb1baf4b6f83f83e7f7d813a1d6e00f/Doc/Periodic_stimulation.rst

Periodic stimulation
--------------------------

In the `periodic stimulation experiment <../Experiments/Periodic_stimulation.cellml>`_, the `Membrane potential component <../Components/Membrane_potential.cellml/view>`_ is configured and parameterised with an applied `periodic stimulus current <../Experiments/Periodic_IStim_protocol.cellml>`_. 

You can change the parameters of stimulation in the component ``Istim_parameters``. 

You can also bypass the parameters in the component ``model_parameters`` and ``initial_conditions`` and define your own parameters.

The simulation experiment can be obtained by loading the `corresponding SED-ML document <../Simulation/Periodic_stimulation.sedml>`__ into OpenCOR and executing the simulation.

Membrane action potential
-------------------------

Figure [#]_ shows the simulated hJSMC action potential trace after a simulation of 30 minutes of electrical activity and free intracellular calcium concentration.

.. [#]

.. figure::  ../Simulation/simFig8.png
   :width: 85%
   :align: center
   :alt: simFig8

   Simulated hJSMC action potentials after a simulation of 30 minutes of electrical activity and free intracellular calcium concentration.