Location: Model of Human Jejunal Smooth Muscle Cell Electrophysiology @ 209ecb42181f / Components / INCX.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2021-06-21 15:32:15+12:00
Desc:
Correct the figure numbers in the doc and typos; Change the default temerature back to 310K for Periodic_stimulation.
Permanent Source URI:
https://models.physiomeproject.org/workspace/692/rawfile/209ecb42181f3204db0c1119bff2279b6a9b50e0/Components/INCX.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="INCX" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="units.cellml">
        <units name="mM" units_ref="mM"/>
        <units name="pA" units_ref="pA"/>
        <units name="mV" units_ref="mV"/>
        <units name="J_per_K_mol" units_ref="J_per_K_mol"/>
        <units name="C_per_mmol" units_ref="C_per_mmol"/>
    </import>
    <component name="INCX">
        <variable name="I_NCX" public_interface="out" units="pA"/>
        <variable name="V" public_interface="in" units="mV"/>
        <variable name="R" public_interface="in" units="J_per_K_mol"/>
        <variable name="T" public_interface="in" units="kelvin"/>
        <variable name="F" public_interface="in" units="C_per_mmol"/>
        <variable name="K_mCa" public_interface="in" units="mM"/>
        <variable name="K_mNai" public_interface="in" units="mM"/>
        <variable name="k_sat" public_interface="in" units="dimensionless"/>
        <variable name="gamma" public_interface="in" units="dimensionless"/>
        <variable name="Nao" public_interface="in" units="mM"/>
        <variable name="Nai" public_interface="in" units="mM"/>
        <variable name="Cai" public_interface="in" units="mM"/>
        <variable name="Cao" public_interface="in" units="mM"/>
        <variable name="P_NCX" public_interface="in" units="pA"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>I_NCX</ci>
                <apply>
                    <divide/>
                    <apply>
                        <times/>
                        <ci>P_NCX</ci>
                        <apply>
                            <minus/>
                            <apply>
                                <times/>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <times/>
                                            <ci>gamma</ci>
                                            <ci>V</ci>
                                            <ci>F</ci>
                                        </apply>
                                        <apply>
                                            <times/>
                                            <ci>R</ci>
                                            <ci>T</ci>
                                        </apply>
                                    </apply>
                                </apply>
                                <apply>
                                    <power/>
                                    <ci>Nai</ci>
                                    <cn cellml:units="dimensionless">3</cn>
                                </apply>
                                <ci>Cao</ci>
                            </apply>
                            <apply>
                                <times/>
                                <cn cellml:units="dimensionless">2.5</cn>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <times/>
                                            <apply>
                                                <minus/>
                                                <ci>gamma</ci>
                                                <cn cellml:units="dimensionless">1</cn>
                                            </apply>
                                            <ci>V</ci>
                                            <ci>F</ci>
                                        </apply>
                                        <apply>
                                            <times/>
                                            <ci>R</ci>
                                            <ci>T</ci>
                                        </apply>
                                    </apply>
                                </apply>
                                <apply>
                                    <power/>
                                    <ci>Nao</ci>
                                    <cn cellml:units="dimensionless">3</cn>
                                </apply>
                                <ci>Cai</ci>
                            </apply>
                        </apply>
                    </apply>
                    <apply>
                        <times/>
                        <apply>
                            <plus/>
                            <apply>
                                <power/>
                                <ci>K_mNai</ci>
                                <cn cellml:units="dimensionless">3</cn>
                            </apply>
                            <apply>
                                <power/>
                                <ci>Nao</ci>
                                <cn cellml:units="dimensionless">3</cn>
                            </apply>
                        </apply>
                        <apply>
                            <plus/>
                            <ci>K_mCa</ci>
                            <ci>Cao</ci>
                        </apply>
                        <apply>
                            <plus/>
                            <cn cellml:units="dimensionless">1</cn>
                            <apply>
                                <times/>
                                <ci>k_sat</ci>
                                <apply>
                                    <exp/>
                                    <apply>
                                        <divide/>
                                        <apply>
                                            <times/>
                                            <apply>
                                                <minus/>
                                                <ci>gamma</ci>
                                                <cn cellml:units="dimensionless">1</cn>
                                            </apply>
                                            <ci>V</ci>
                                            <ci>F</ci>
                                        </apply>
                                        <apply>
                                            <times/>
                                            <ci>R</ci>
                                            <ci>T</ci>
                                        </apply>
                                    </apply>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
</model>