Location: Neurovascular Coupling @ 7b90678da579 / README.txt

Author:
ssu655 <ssu655@aucklanduni.ac.nz>
Date:
2020-03-11 15:47:09+13:00
Desc:
Updated the parameters and initial conditions to produce the exact same plots as primary paper.
Permanent Source URI:
https://models.physiomeproject.org/workspace/5c8/rawfile/7b90678da57988fcc144f08a44b2806529313414/README.txt

===============================================
Reproduction of the results of the primary paper

Figure 8 in the primary paper is the results to be reproduced. The correspondence between the figures are as following:

Primary publication	-- Pysiome paper
Figure 8A        	-- Figure 4(top) 
Figure 8B        	-- Figure 4(middle,bottom)
Figure 8C      	-- Figure 5

===============================================
Instructions on obtaining the figures:

- In OpenCOR, open Mnm1_p7.cellml file in simulation mode.

- Run simulation in accordance with the specifications in the publication. 

- Reproduce Figure 4(top) by plotting variable y. In Parameters tab, left click y and select "Plot Against Variable Of Integration". 

- Open a new graph panel, reproduce Figure 4(middle) and Figure 4(bottom) by plotting variables q_o_2 and q_glucose, respectively. 

- Reproduce Figure 5 by plotting variables k_flow, k_inhibiting and k_stimulating in the same graph panel. 

- Customize the x axis of all plots to a range of 50-70 seconds, by left click any graph panels and select "Custom Axes...".