- Author:
- Michael Pan <mpan92@gmail.com>
- Date:
- 2020-08-27 08:39:13+10:00
- Desc:
- Fixed units
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/4ce/rawfile/6baaa1d0bfa1a0772c316ab59631b619df2601f4/Code/CellML/Terkildsen_NaK_kinetic_modular.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model cmeta:id="metaid0" name="Terkildsen_NaK_kinetic_modular" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<units name="per_second_per_mM">
<unit exponent="-1.0" units="mM"/>
<unit exponent="-1.0" units="second"/>
</units>
<units name="mV">
<unit prefix="milli" units="volt"/>
</units>
<units name="per_second3">
<unit exponent="-3.0" units="second"/>
</units>
<units name="C_per_mol">
<unit exponent="-1.0" units="mole"/>
<unit units="coulomb"/>
</units>
<units name="mV_per_sec">
<unit exponent="-1.0" units="second"/>
<unit units="mV"/>
</units>
<units name="per_second_per_mM2">
<unit exponent="-1.0" units="second"/>
<unit exponent="-2.0" units="mM"/>
</units>
<units name="mM">
<unit prefix="milli" units="mole"/>
</units>
<units name="per_second">
<unit exponent="-1.0" units="second"/>
</units>
<units name="mJ_per_K_per_mol">
<unit exponent="-1.0" units="mole"/>
<unit prefix="milli" units="joule"/>
<unit exponent="-1.0" units="kelvin"/>
</units>
<component name="environment">
<variable cmeta:id="environment.R" initial_value="8314" name="R" units="mJ_per_K_per_mol"/>
<variable cmeta:id="environment.T" initial_value="310" name="T" units="kelvin"/>
<variable cmeta:id="environment.F" initial_value="96485" name="F" units="C_per_mol"/>
<variable cmeta:id="environment.K0d_nak_nai" initial_value="579.7295" name="K0d_nak_nai" units="mM"/>
<variable cmeta:id="environment.K0d_nak_nae" initial_value="0.0349" name="K0d_nak_nae" units="mM"/>
<variable cmeta:id="environment.Kd_nak_nai2" initial_value="5.6399" name="Kd_nak_nai2" units="mM"/>
<variable cmeta:id="environment.Kd_nak_nae2" initial_value="1.0617e4" name="Kd_nak_nae2" units="mM"/>
<variable cmeta:id="environment.Kd_nak_ke" initial_value="1.0817" name="Kd_nak_ke" units="mM"/>
<variable cmeta:id="environment.Kd_nak_ki" initial_value="1.6795e4" name="Kd_nak_ki" units="mM"/>
<variable cmeta:id="environment.Kd_nak_MgATP" initial_value="140.3709" name="Kd_nak_MgATP" units="mM"/>
<variable cmeta:id="environment.rate_f_nak_1" initial_value="1.4232e3" name="rate_f_nak_1" units="per_second"/>
<variable cmeta:id="environment.rate_f_nak_2" initial_value="1.1565e4" name="rate_f_nak_2" units="per_second"/>
<variable cmeta:id="environment.rate_f_nak_3" initial_value="194.4506" name="rate_f_nak_3" units="per_second"/>
<variable cmeta:id="environment.rate_f_nak_4" initial_value="3.0630e4" name="rate_f_nak_4" units="per_second"/>
<variable cmeta:id="environment.rate_r_nak_1" initial_value="225.9048" name="rate_r_nak_1" units="per_second_per_mM"/>
<variable cmeta:id="environment.rate_r_nak_2" initial_value="3.6355e4" name="rate_r_nak_2" units="per_second"/>
<variable cmeta:id="environment.rate_r_nak_3" initial_value="2.8104e5" name="rate_r_nak_3" units="per_second_per_mM2"/>
<variable cmeta:id="environment.rate_r_nak_4" initial_value="1.5740e6" name="rate_r_nak_4" units="per_second"/>
<variable cmeta:id="environment.factor_nak_del" initial_value="-0.0550" name="factor_nak_del" units="dimensionless"/>
<variable cmeta:id="environment.pKd_nak_hpi" initial_value="6.7700" name="pKd_nak_hpi" units="dimensionless"/>
<variable cmeta:id="environment.Kd_nak_kpi" initial_value="292" name="Kd_nak_kpi" units="mM"/>
<variable cmeta:id="environment.Kd_nak_napi" initial_value="224" name="Kd_nak_napi" units="mM"/>
<variable cmeta:id="environment.Nae" name="Nae" public_interface="in" units="mM"/>
<variable cmeta:id="environment.Vm" name="Vm" public_interface="in" units="mV"/>
<variable cmeta:id="environment.Ki" initial_value="0" name="Ki" units="mM"/>
<variable cmeta:id="environment.Ke" initial_value="5.4" name="Ke" units="mM"/>
<variable cmeta:id="environment.Nai" initial_value="50" name="Nai" units="mM"/>
<variable cmeta:id="environment.MgATP" initial_value="10" name="MgATP" units="mM"/>
<variable cmeta:id="environment.MgADP" initial_value="0" name="MgADP" units="mM"/>
<variable cmeta:id="environment.Pi_total" initial_value="0" name="Pi_total" units="mM"/>
<variable cmeta:id="environment.H" initial_value="3.9811e-5" name="H" units="mM"/>
<variable cmeta:id="environment.Pi" name="Pi" units="mM"/>
<variable cmeta:id="environment.Kd_nak_nae1" name="Kd_nak_nae1" units="mM"/>
<variable cmeta:id="environment.Kd_nak_nai1" name="Kd_nak_nai1" units="mM"/>
<variable cmeta:id="environment.Nae_bound1" name="Nae_bound1" units="dimensionless"/>
<variable cmeta:id="environment.Nai_bound1" name="Nai_bound1" units="dimensionless"/>
<variable cmeta:id="environment.Nae_bound2" name="Nae_bound2" units="dimensionless"/>
<variable cmeta:id="environment.Nai_bound2" name="Nai_bound2" units="dimensionless"/>
<variable cmeta:id="environment.Ke_bound" name="Ke_bound" units="dimensionless"/>
<variable cmeta:id="environment.Ki_bound" name="Ki_bound" units="dimensionless"/>
<variable cmeta:id="environment.MgATP_bound" name="MgATP_bound" units="dimensionless"/>
<variable cmeta:id="environment.alpha_f_nak_1" name="alpha_f_nak_1" units="per_second"/>
<variable cmeta:id="environment.alpha_f_nak_2" name="alpha_f_nak_2" units="per_second"/>
<variable cmeta:id="environment.alpha_f_nak_3" name="alpha_f_nak_3" units="per_second"/>
<variable cmeta:id="environment.alpha_f_nak_4" name="alpha_f_nak_4" units="per_second"/>
<variable cmeta:id="environment.alpha_r_nak_1" name="alpha_r_nak_1" units="per_second"/>
<variable cmeta:id="environment.alpha_r_nak_2" name="alpha_r_nak_2" units="per_second"/>
<variable cmeta:id="environment.alpha_r_nak_3" name="alpha_r_nak_3" units="per_second"/>
<variable cmeta:id="environment.alpha_r_nak_4" name="alpha_r_nak_4" units="per_second"/>
<variable cmeta:id="environment.sig_nak" name="sig_nak" units="per_second3"/>
<variable cmeta:id="environment.v_cyc_nak" name="v_cyc_nak" public_interface="out" units="per_second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Pi</ci>
<apply>
<divide/>
<ci>Pi_total</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>Ki</ci>
<ci>Kd_nak_kpi</ci>
</apply>
<apply>
<divide/>
<ci>H</ci>
<apply>
<power/>
<cn cellml:units="dimensionless">10</cn>
<apply>
<minus/>
<cn cellml:units="dimensionless">3.0</cn>
<ci>pKd_nak_hpi</ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<ci>Nai</ci>
<ci>Kd_nak_napi</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Kd_nak_nae1</ci>
<apply>
<times/>
<ci>K0d_nak_nae</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>factor_nak_del</ci>
</apply>
<ci>F</ci>
<ci>Vm</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Kd_nak_nai1</ci>
<apply>
<times/>
<ci>K0d_nak_nai</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>factor_nak_del</ci>
<ci>F</ci>
<ci>Vm</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Nae_bound1</ci>
<apply>
<divide/>
<ci>Nae</ci>
<ci>Kd_nak_nae1</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Nai_bound1</ci>
<apply>
<divide/>
<ci>Nai</ci>
<ci>Kd_nak_nai1</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Nae_bound2</ci>
<apply>
<divide/>
<ci>Nae</ci>
<ci>Kd_nak_nae2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Nai_bound2</ci>
<apply>
<divide/>
<ci>Nai</ci>
<ci>Kd_nak_nai2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Ke_bound</ci>
<apply>
<divide/>
<ci>Ke</ci>
<ci>Kd_nak_ke</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Ki_bound</ci>
<apply>
<divide/>
<ci>Ki</ci>
<ci>Kd_nak_ki</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>MgATP_bound</ci>
<apply>
<divide/>
<ci>MgATP</ci>
<ci>Kd_nak_MgATP</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_f_nak_1</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>rate_f_nak_1</ci>
<ci>Nai_bound1</ci>
<apply>
<power/>
<ci>Nai_bound2</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>Nai_bound1</ci>
<apply>
<power/>
<ci>Nai_bound2</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<ci>Nai_bound2</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Ki_bound</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_f_nak_2</ci>
<ci>rate_f_nak_2</ci>
</apply>
<apply>
<eq/>
<ci>alpha_f_nak_3</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>rate_f_nak_3</ci>
<apply>
<power/>
<ci>Ke_bound</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>Nae_bound1</ci>
<apply>
<power/>
<ci>Nae_bound2</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Nae_bound2</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Ke_bound</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_f_nak_4</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>rate_f_nak_4</ci>
<ci>MgATP_bound</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>MgATP_bound</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_r_nak_1</ci>
<apply>
<times/>
<ci>rate_r_nak_1</ci>
<ci>MgADP</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_r_nak_2</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>rate_r_nak_2</ci>
<ci>Nae_bound1</ci>
<apply>
<power/>
<ci>Nae_bound2</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>Nae_bound1</ci>
<apply>
<power/>
<ci>Nae_bound2</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Nae_bound2</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Ke_bound</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_r_nak_3</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>rate_r_nak_3</ci>
<ci>Pi</ci>
<ci>H</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>MgATP_bound</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_r_nak_4</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>rate_r_nak_4</ci>
<apply>
<power/>
<ci>Ki_bound</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>Nai_bound1</ci>
<apply>
<power/>
<ci>Nai_bound2</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Nai_bound2</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<ci>Ki_bound</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>sig_nak</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>alpha_r_nak_1</ci>
<ci>alpha_r_nak_2</ci>
<ci>alpha_r_nak_3</ci>
</apply>
<apply>
<times/>
<ci>alpha_r_nak_1</ci>
<ci>alpha_r_nak_2</ci>
<ci>alpha_f_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_r_nak_1</ci>
<ci>alpha_f_nak_3</ci>
<ci>alpha_f_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_2</ci>
<ci>alpha_f_nak_3</ci>
<ci>alpha_f_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_r_nak_2</ci>
<ci>alpha_r_nak_3</ci>
<ci>alpha_r_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_1</ci>
<ci>alpha_r_nak_2</ci>
<ci>alpha_r_nak_3</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_1</ci>
<ci>alpha_r_nak_2</ci>
<ci>alpha_f_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_1</ci>
<ci>alpha_f_nak_3</ci>
<ci>alpha_f_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_r_nak_1</ci>
<ci>alpha_r_nak_3</ci>
<ci>alpha_r_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_2</ci>
<ci>alpha_r_nak_3</ci>
<ci>alpha_r_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_1</ci>
<ci>alpha_f_nak_2</ci>
<ci>alpha_r_nak_3</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_1</ci>
<ci>alpha_f_nak_2</ci>
<ci>alpha_f_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_r_nak_1</ci>
<ci>alpha_r_nak_2</ci>
<ci>alpha_r_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_r_nak_1</ci>
<ci>alpha_f_nak_3</ci>
<ci>alpha_r_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_2</ci>
<ci>alpha_f_nak_3</ci>
<ci>alpha_r_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_f_nak_1</ci>
<ci>alpha_f_nak_2</ci>
<ci>alpha_f_nak_3</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_cyc_nak</ci>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>alpha_f_nak_1</ci>
<ci>alpha_f_nak_2</ci>
<ci>alpha_f_nak_3</ci>
<ci>alpha_f_nak_4</ci>
</apply>
<apply>
<times/>
<ci>alpha_r_nak_1</ci>
<ci>alpha_r_nak_2</ci>
<ci>alpha_r_nak_3</ci>
<ci>alpha_r_nak_4</ci>
</apply>
</apply>
<ci>sig_nak</ci>
</apply>
</apply>
</math>
</component>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.K0d_nak_nai">
<semsim:isComputationalComponentFor xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#property_0">
<semsim:physicalPropertyOf xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
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<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="http://identifiers.org/fma/FMA:14067" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
</ro:part_of>
<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Voltage-dependent dissociation constant of intracellular Na+</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
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</rdf:Description>
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.K0d_nak_nae">
<semsim:isComputationalComponentFor xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#property_1">
<semsim:physicalPropertyOf xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
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<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Voltage-dependent dissociation constant of extracellular Na+</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
</semsim:isComputationalComponentFor>
</rdf:Description>
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.Kd_nak_MgATP">
<semsim:isComputationalComponentFor xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#property_6">
<semsim:physicalPropertyOf xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#entity_7">
<ro:part_of xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" rdf:resource="#entity_1" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Dissociation constant of MgATP</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
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<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Voltage-independent dissociation of extracellular Na+</semsim:name>
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<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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<ro:part_of xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" rdf:resource="#entity_1" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Voltage-independent dissociation of intracellular Na+</semsim:name>
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<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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<dcterms:description xmlns:dcterms="http://purl.org/dc/terms/">Cycling velocity</dcterms:description>
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<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00378" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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<dcterms:description xmlns:dcterms="http://purl.org/dc/terms/">Membrane potential</dcterms:description>
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<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.Pi">
<semsim:isComputationalComponentFor xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
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<semsim:physicalPropertyOf xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#entity_8">
<ro:part_of xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" rdf:resource="#entity_1" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/chebi/CHEBI:24838" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.t">
<bqbiol:is xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" rdf:resource="https://identifiers.org/opb/OPB_01023" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.Kd_nak_ke">
<semsim:isComputationalComponentFor xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#property_4">
<semsim:physicalPropertyOf xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#entity_5">
<ro:part_of xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" rdf:resource="#entity_1" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Dissociation constant of extracellular K+</semsim:name>
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<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
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<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.Kd_nak_nae2">
<semsim:isComputationalComponentFor xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#property_3">
<semsim:physicalPropertyOf xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#entity_4">
<ro:part_of xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" rdf:resource="#entity_1" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Voltage-independent dissociation constant for extracellular Na+</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
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</rdf:Description>
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.Kd_nak_ki">
<semsim:isComputationalComponentFor xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#property_5">
<semsim:physicalPropertyOf xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#entity_6">
<ro:part_of xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" rdf:resource="#entity_1" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Dissociation constant of intracellular K+</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
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</rdf:Description>
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#environment.Kd_nak_nai2">
<semsim:isComputationalComponentFor xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#property_2">
<semsim:physicalPropertyOf xmlns:semsim="http://www.bhi.washington.edu/SemSim#">
<rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#entity_3">
<semsim:name xmlns:semsim="http://www.bhi.washington.edu/SemSim#">Voltage-independent dissociation constant of intracellular Na+</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition xmlns:semsim="http://www.bhi.washington.edu/SemSim#" rdf:resource="https://identifiers.org/opb/OPB_00340" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"/>
</rdf:Description>
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