Location: Diabetes @ 85a51a743db0 / BondGraph / InsulinBinding.cellml
- Author:
- Soroush Safaei <ssaf006@aucklanduni.ac.nz>
- Date:
- 2018-03-16 18:20:41+13:00
- Desc:
- diagram
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/483/rawfile/85a51a743db03c76f120c12baf530deae983c8d2/BondGraph/InsulinBinding.cellml
<?xml version='1.0'?>
<model name="InsulinBindingLevel" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="Units.cellml">
<units name="per_mol" units_ref="per_mol"/>
<units name="J_per_mol" units_ref="J_per_mol"/>
<units name="J_per_mol_K" units_ref="J_per_mol_K"/>
<units name="mol_per_s" units_ref="mol_per_s"/>
</import>
<component name="state">
<variable initial_value="0.0" name="t" units="second"/>
<!-- Parameters-->
<variable initial_value="8.324" name="R" units="J_per_mol_K"/>
<variable initial_value="300" name="T" units="kelvin"/>
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<variable initial_value="0.20655419999563508401727960913329" name="K_q2" units="per_mol"/>
<variable initial_value="2.4943252381047456297931099512349" name="K_q3" units="per_mol"/>
<variable initial_value="1.1665847641376448313261474962398" name="K_q4" units="per_mol"/>
<variable initial_value="6.2920209735810257656545179406341" name="K_q5" units="per_mol"/>
<variable initial_value="135.74505393527089281313886429079" name="K_q6" units="per_mol"/>
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<variable initial_value="0.32870827678129609268129865385271" name="K_q11" units="per_mol"/>
<variable initial_value="147257110.37578193240869635674704" name="K_q12" units="per_mol"/>
<variable initial_value="0.022184975175281413643787301874773" name="K_q13" units="per_mol"/>
<variable initial_value="81.393454351718475892655833918232" name="K_q14" units="per_mol"/>
<variable initial_value="5.7225380418903459025816388165654" name="K_q15" units="per_mol"/>
<variable initial_value="1.0" name="K_q16" units="per_mol"/>
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<!-- var K_Re29: mol_per_s {init: 1.0};-->
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<minus/>
<apply>
<times/>
<ci>K_q12</ci>
<ci>q12</ci>
<ci>K_q9</ci>
<ci>q9</ci>
</apply>
<apply>
<times/>
<ci>K_q7</ci>
<ci>q7</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re14</ci>
<apply>
<times/>
<ci>K_Re14</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q12</ci>
<ci>q12</ci>
<ci>K_q9</ci>
<ci>q9</ci>
</apply>
<apply>
<times/>
<ci>K_q11</ci>
<ci>q11</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re15</ci>
<apply>
<times/>
<ci>K_Re15</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q12</ci>
<ci>q12</ci>
<ci>K_q7</ci>
<ci>q7</ci>
</apply>
<apply>
<times/>
<ci>K_q8</ci>
<ci>q8</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re16</ci>
<apply>
<times/>
<ci>K_Re16</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q12</ci>
<ci>q12</ci>
<ci>K_q11</ci>
<ci>q11</ci>
</apply>
<apply>
<times/>
<ci>K_q8</ci>
<ci>q8</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re17</ci>
<apply>
<times/>
<ci>K_Re17</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q12</ci>
<ci>q12</ci>
<ci>K_q9</ci>
<ci>q9</ci>
</apply>
<apply>
<times/>
<ci>K_q10</ci>
<ci>q10</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re18</ci>
<apply>
<times/>
<ci>K_Re18</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q12</ci>
<ci>q12</ci>
<ci>K_q11</ci>
<ci>q11</ci>
</apply>
<apply>
<times/>
<ci>K_q10</ci>
<ci>q10</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re19</ci>
<apply>
<times/>
<ci>K_Re19</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q9</ci>
<ci>q9</ci>
</apply>
<apply>
<times/>
<ci>K_q13</ci>
<ci>q13</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re20</ci>
<apply>
<times/>
<ci>K_Re20</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q8</ci>
<ci>q8</ci>
</apply>
<apply>
<times/>
<ci>K_q13</ci>
<ci>q13</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re21</ci>
<apply>
<times/>
<ci>K_Re21</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q10</ci>
<ci>q10</ci>
</apply>
<apply>
<times/>
<ci>K_q13</ci>
<ci>q13</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re22</ci>
<apply>
<times/>
<ci>K_Re22</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q11</ci>
<ci>q11</ci>
</apply>
<apply>
<times/>
<ci>K_q13</ci>
<ci>q13</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re23</ci>
<apply>
<times/>
<ci>K_Re23</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q7</ci>
<ci>q7</ci>
</apply>
<apply>
<times/>
<ci>K_q13</ci>
<ci>q13</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re24</ci>
<apply>
<times/>
<ci>K_Re24</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q14</ci>
<ci>q14</ci>
</apply>
<apply>
<times/>
<ci>K_q13</ci>
<ci>q13</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re25</ci>
<apply>
<times/>
<ci>K_Re25</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q13</ci>
<ci>q13</ci>
</apply>
<apply>
<times/>
<ci>K_q15</ci>
<ci>q15</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re26</ci>
<apply>
<times/>
<ci>K_Re26</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q14</ci>
<ci>q14</ci>
</apply>
<apply>
<times/>
<ci>K_q1</ci>
<ci>q1</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re27</ci>
<apply>
<times/>
<ci>K_Re27</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q15</ci>
<ci>q15</ci>
</apply>
<apply>
<times/>
<ci>K_q1</ci>
<ci>q1</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_Re28</ci>
<apply>
<times/>
<ci>K_Re28</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_q16</ci>
<ci>q16</ci>
</apply>
<apply>
<times/>
<ci>K_q17</ci>
<ci>q17</ci>
</apply>
</apply>
</apply>
</apply>
</math>
<!-- v_Re29 = K_Re29*(K_q17*q15-K_q1*q1);-->
</component>
</model>