- Author:
- Soroush <ssaf006@aucklanduni.ac.nz>
- Date:
- 2016-08-15 18:43:54+12:00
- Desc:
- fix ref
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/34d/rawfile/5d1fde5298575e8780161433ad2d9fb229294290/CO2.cellml
<?xml version='1.0'?>
<!-- Leem, C. H., & Vaughan-Jones, R. D. (1998). Out-of-equilibrium pH transients in the guinea-pig ventricular myocyte. The Journal of Physiology, 509(2), 471-485.-->
<model cmeta:id="CO2_hydration" name="CO2_hydration" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="Units/Units.cellml">
<units name="mM" units_ref="mM"/>
<units name="per_s" units_ref="per_s"/>
<units name="mM_per_s" units_ref="mM_per_s"/>
</import>
<component name="Hydration">
<variable name="J" public_interface="out" units="mM_per_s"/>
<variable initial_value="0.365" name="k_1" units="per_s"/>
<variable initial_value="4.8e+5" name="k_2" units="per_s"/>
<variable name="pH" public_interface="in" units="dimensionless"/>
<variable name="CO2" public_interface="in" units="mM"/>
<variable name="HCO3" public_interface="in" units="mM"/>
<!-- If J_hyd > 0 then CO2 + H2O --> H+ + HCO3- -->
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>k_1</ci>
<ci>CO2</ci>
</apply>
<apply>
<times/>
<ci>k_2</ci>
<cn cellml:units="dimensionless" type="e-notation">1<sep/>3</cn>
<apply>
<power/>
<cn cellml:units="dimensionless">10</cn>
<apply>
<minus/>
<ci>pH</ci>
</apply>
</apply>
<ci>HCO3</ci>
</apply>
</apply>
</apply>
</math>
</component>
</model>
