- Author:
- Soroush Safaei <ssaf006@aucklanduni.ac.nz>
- Date:
- 2016-03-11 18:19:57+13:00
- Desc:
- 1
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/295/rawfile/59e69f3865a193dc8d74d910e6331b410fb2dda6/Oyehaug_2009_NBC.cellml
<?xml version='1.0'?>
<!-- This CellML file was generated from:
Østby, Ivar, et al. "Astrocytic mechanisms explaining neural-activity-induced shrinkage of extraneuronal space." PLoS Comput Biol 5.1 (2009): e1000272.-->
<model cmeta:id="Oyehaug_2009_NBC" name="Oyehaug_2009_NBC" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="Units.cellml">
<units name="mM" units_ref="mM"/>
<units name="mM_per_s" units_ref="mM_per_s"/>
<units name="mV" units_ref="mV"/>
<units name="mV_per_s" units_ref="mV_per_s"/>
<units name="joule_per_mmole" units_ref="joule_per_mmole"/>
<units name="mmole_per_joule" units_ref="mmole_per_joule"/>
<units name="coulomb_per_mmole" units_ref="coulomb_per_mmole"/>
<units name="microS_per_cm2" units_ref="microS_per_cm2"/>
</import>
<component name="NBC">
<variable name="V_m" public_interface="in" units="volt"/>
<variable name="Na_int" public_interface="in" units="mM"/>
<variable name="Na_ext" public_interface="in" units="mM"/>
<variable name="HCO3_int" public_interface="in" units="mM"/>
<variable name="HCO3_ext" public_interface="in" units="mM"/>
<variable name="E_NBC" units="volt"/>
<variable initial_value="80.0" name="g_NBC" units="microS_per_cm2"/>
<variable initial_value="96.5" name="F" units="coulomb_per_mmole"/>
<variable initial_value="2.57734" name="RT" units="joule_per_mmole"/>
<variable initial_value="2" name="n" units="dimensionless"/>
<variable name="J_NBC" public_interface="out" units="mM_per_s"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>E_NBC</ci>
<apply>
<times/>
<apply>
<divide/>
<ci>RT</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>n</ci>
</apply>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<times/>
<apply>
<divide/>
<ci>Na_ext</ci>
<ci>Na_int</ci>
</apply>
<apply>
<power/>
<apply>
<divide/>
<ci>HCO3_ext</ci>
<ci>HCO3_int</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>J_NBC</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>g_NBC</ci>
<apply>
<minus/>
<ci>V_m</ci>
<ci>E_NBC</ci>
</apply>
</apply>
<ci>F</ci>
</apply>
</apply>
</math>
</component>
</model>
