Location: Na+/HCO3- Cotransporter @ 59e69f3865a1 / NBC_test.cellml

Author:
Soroush Safaei <ssaf006@aucklanduni.ac.nz>
Date:
2016-03-11 18:19:57+13:00
Desc:
1
Permanent Source URI:
https://models.physiomeproject.org/workspace/295/rawfile/59e69f3865a193dc8d74d910e6331b410fb2dda6/NBC_test.cellml

<?xml version='1.0'?>
<!-- This CellML file was generated from:
 Østby, Ivar, et al. "Astrocytic mechanisms explaining neural-activity-induced shrinkage of extraneuronal space." PLoS Comput Biol 5.1 (2009): e1000272.-->
<model cmeta:id="Oyehaug_2009_NBC" name="Oyehaug_2009_NBC" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="Units.cellml">
        <units name="mM" units_ref="mM"/>
        <units name="mM_per_s" units_ref="mM_per_s"/>
        <units name="mV" units_ref="mV"/>
        <units name="mV_per_s" units_ref="mV_per_s"/>
        <units name="joule_per_mmole" units_ref="joule_per_mmole"/>
        <units name="mmole_per_joule" units_ref="mmole_per_joule"/>
        <units name="coulomb_per_mmole" units_ref="coulomb_per_mmole"/>
        <units name="microS_per_cm2" units_ref="microS_per_cm2"/>
    </import>
    <import xlink:href="Oyehaug_2009_NBC.cellml">
        <component component_ref="NBC" name="NBC"/>
    </import>
    <component name="environment">
        <variable name="time" public_interface="out" units="second"/>
    </component>
    <component name="concentrations">
        <variable name="time" public_interface="in" units="second"/>
        <variable initial_value="-0.032" name="V_m" public_interface="out" units="volt"/>
        <variable initial_value="15.0" name="Na_int" public_interface="out" units="mM"/>
        <variable initial_value="146.0" name="Na_ext" public_interface="out" units="mM"/>
        <variable initial_value="9.0" name="HCO3_int" public_interface="out" units="mM"/>
        <variable initial_value="15.0" name="HCO3_ext" public_interface="out" units="mM"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>Na_int</ci>
                </apply>
                <cn cellml:units="mM_per_s">1.0</cn>
            </apply>
        </math>
    </component>
    <component name="fluxes">
        <variable name="J_NBC" public_interface="in" units="mM_per_s"/>
    </component>
    <connection>
        <map_components component_1="concentrations" component_2="NBC"/>
        <map_variables variable_1="Na_int" variable_2="Na_int"/>
        <map_variables variable_1="Na_ext" variable_2="Na_ext"/>
        <map_variables variable_1="HCO3_int" variable_2="HCO3_int"/>
        <map_variables variable_1="HCO3_ext" variable_2="HCO3_ext"/>
        <map_variables variable_1="V_m" variable_2="V_m"/>
    </connection>
    <connection>
        <map_components component_1="fluxes" component_2="NBC"/>
        <map_variables variable_1="J_NBC" variable_2="J_NBC"/>
    </connection>
    <connection>
        <map_components component_1="concentrations" component_2="environment"/>
        <map_variables variable_1="time" variable_2="time"/>
    </connection>
</model>