Model Mathematics

Component: environment

Component: Cdc13_Cdc2

ddtimeCdc13_Cdc2=k1mass+kcdc25Cdc13_P_Cdc2+Rum1_Cdc13_Cdc2kir+k4-kweeCdc13_Cdc2+kiCdc13_Cdc2Rum1+k2Cdc13_Cdc2

Component: Cdc13_P_Cdc2

ddtimeCdc13_P_Cdc2=kweeCdc13_Cdc2-kcdc25Cdc13_P_Cdc2+k2Cdc13_P_Cdc2

Component: Rum1_Cdc13_Cdc2

ddtimeRum1_Cdc13_Cdc2=kiRum1Cdc13_Cdc2-Rum1_Cdc13_Cdc2k4+k2c+kir

Component: Rum1

ddtimeRum1=k3+Rum1_Cdc13_Cdc2kir+k2c-k4Rum1+kiCdc13_Cdc2Rum1

Component: Cdc25P

ddtimeCdc25P=k25MPF1-Cdc25PJ25+1-Cdc25P-k25rCdc25PJ25r+Cdc25P k25r=k25r_+ks

Component: Wee1

ddtimeWee1=kwr1-Wee1Jwr+1-Wee1-kwMPFWee1Jw+Wee1 kwr=kwr_+ks

Component: Mik1

ddtimeMik1=kmr1-Mik1Jmr+1-Mik1-kmMik1Jm+Mik1 kmr=kmr_+ks

Component: AAE_total

ddtimeAAE_total=kasMPF-kadAAE_total

Component: AAE

ddtimeAAE=kaa+kaa_MPFAAE_total-AAEJaa+AAE_total-AAE-kaiAAEJai+AAE+kadAAE kai=kai_+kx

Component: APC

ddtimeAPC=kapr+kapr_AAE1-APCJapr+1-APC-kapPuc1mass+MPFAPCJap+APC

Component: mass

ddtimemass=mumass

Component: k2

k2=V21-APC+V2_APC

Component: k2c

k2c=V2c1-APC+V2c_APC

Component: k4

k4=k4_+k4__Puc1mass+MPF

Component: kcdc25

kcdc25=V251-Cdc25P+V25_Cdc25P

Component: kwee

kwee=Vwee1-Wee11+Vwee_Wee1+Vmik1-Mik11+Vmik_Mik1

Component: MPF

MPF=Cdc13_Cdc2+alphaCdc13_P_Cdc2

Component: parameters

ks=0.5ifAPC0.20otherwise