Model Mathematics

Component: environment

Component: Parameters

Component: ligand

Component: RS

ddtimeRS=k_rR_T-k_r+k_pLK_1+LRS-k_rRS_p

Component: RS_p

ddtimeRS_p=Lk_pRSK_1+L-k_eRS_pK_2+L

Component: G_GTP

ddtimeG=k_adelta+rho_rG_T-G-k_dG

Component: IP_3

ddtimeIP_3=r_hPIP_2N_av-k_degIP_3

Component: PIP_2

ddtimePIP_2=-r_h+r_rPIP_2-r_rN_avIP_3+r_rPIP_2_T

Component: r_h

r_h=alphaCK_c+CG

Component: rho_r

rho_r=LRSxiR_TK_1+L

Component: C

ddtimeC=betaepsilon_reta_1m_infinit3h3+eta_2C_ER-C-eta_3C2k_32+C2

Component: h

ddtimeh=h_infinit-htau_h

Component: tau_h

tau_h=a_2zeta+C-1

Component: h_infinit

h_infinit=zetazeta+C

Component: zeta

zeta=d_2IP_3+d_1IP_3+d_3

Component: m_infinit

m_infinit=IP_3d_1+IP_3Cd_5+C

Component: beta

beta=1+K_eB_eK_e+C2+K_xB_xK_x+C2-1

Component: gamma

gamma=1+B_eK_e+C+B_xK_x+C-1

Component: C_ER

C_ER=K_ERB_ERepsilon_rC_T-Cgamma

Component: RS_E

RS_E=k_r1+k_pk_eK_2+LK_1+Lk_r+k_pLK_1+L+k_rk_pk_eK_2+LK_1+LxiR_T+1-xiR_T