Model Mathematics

Component: environment

Component: Y

ddtimeY=k1-k2Y+k3YC

Component: M

ddtimeM=kcdc25preMPF+k3YC-k2M+kweeM

Component: preMPF

ddtimepreMPF=kweeM-k2preMPF+kcdc25preMPF

Component: Cdc25P

ddtimeCdc25P=k25MCdc25Km25+Cdc25-k25rCdc25PKm25r+Cdc25P k25ro=k25rp

Component: Wee1

ddtimeWee1=-kwMWee1Kmw+Wee1+kwrWee1PKmwr+Wee1P kwro=kwrp

Component: IEP

ddtimeIEP=kieMIEKmie+IE-kierIEPKmier+IEP

Component: APC_

ddtimeAPC_=kapIEPAPCKmap+APC-kaprAPC_Kmapr+APC_

Component: C

C=Cdc2tot-M+preMPF

Component: Cdc25

Cdc25=Cdc25tot-Cdc25P

Component: Wee1P

Wee1P=Wee1tot-Wee1

Component: IE

IE=IEtot-IEP

Component: APC

APC=APCtot-APC_

Component: p

p=sR+q

Component: kinetic_parameters

kcdc25=V25Cdc25+V25_Cdc25P k2=V2APC+V2_APC_ kwee=VweeWee1P+Vwee_Wee1