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Tran, Smith, Loiselle, Crampin, 2009
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A Thermodynamic Model of the Cardiac Sarcoplasmic/Endoplasmic Ca(2+) (SERCA) Pump: the two-state SERCA model
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Model Mathematics
Component based math viewer is available
Component: environment
Component: SERCA
T_Cai
=
Ca_i
kdcai
T_Casr
=
Ca_sr
kdcasr
T_H1
=
H_i
kdh1
T_Hi
=
H_i
n
kdhi
T_Hsr
=
H_i
n
kdhsr
T_H
=
H_i
kdh
T_ATP
=
ATP
kdatp
kdatp
=
k_m1
k_p1
a_p1
=
k_p2
T_ATP
T_Cai
2
T_ATP
T_Cai
2
+
T_Hi
1
+
T_ATP
1
+
T_H1
+
T_Cai
2
a_p2
=
k_p3
T_Hsr
T_Hsr
1
+
T_H
+
T_H
1
+
T_Casr
2
a_m1
=
k_m2
ADP
T_Casr
2
T_H
T_Hsr
1
+
T_H
+
T_H
1
+
T_Casr
2
a_m2
=
k_m3
P_i
T_Hi
T_ATP
T_Cai
2
+
T_Hi
1
+
T_ATP
1
+
T_H1
+
T_Cai
2
s2
=
a_p1
+
a_p2
+
a_m1
+
a_m2
v_cycle
=
a_p1
a_p2
-
a_m1
a_m2
s2
d
d
time
ATP
=
0.1
Source
Derived from workspace
Tran, Smith, Loiselle, Crampin, 2009
at changeset
2253a89a7cc1
.
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This work is licensed under a
Creative Commons Attribution 3.0 Unported License
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A Thermodynamic Model of the Cardiac Sarcoplasmic/Endoplasmic Ca(2+) (SERCA) Pump: the three-state SERCA model
A Thermodynamic Model of the Cardiac Sarcoplasmic/Endoplasmic Ca(2+) (SERCA) Pump: the two-state SERCA model