You are here: Home / Exposures / Li, Rinzel, 1994 / Equations for InsP3 Receptor-mediated [Ca2+]i Oscillations Derived from a Detailed Kinetic Model: A Hodgkin-Huxley Like Formalism

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\frac{d}{d time} (v2) = 0.0

\frac{d}{d time} (v3) = 0.0

\frac{d}{d time} (j_in) = 0.0

\frac{d}{d time} (c0) = epsilon 0.001 (j_in - (\frac{v4 C^{2.0}}{{k_pl}^{2.0} + C^{2.0}}))

\frac{d}{d time} (h) = 0.001 (a d_inh - (h a (C + d_inh)))

factor1 = 0.001 (v1 {(\frac{IP3}{IP3 + d_ip3})}^{3.0} {(\frac{C}{C + d_act})}^{3.0} h^{3.0} + v2)

factor2 = c0 - (C (1.0 + c1))

v3_summand = \frac{v3 0.001 C^{2.0}}{{k_er}^{2.0} + C^{2.0}}

v4_summand = 0.001 epsilon (j_in - (\frac{v4 C^{2.0}}{{k_pl}^{2.0} + C^{2.0}}))

\frac{d}{d time} (C) = (factor1 factor2 - v3_summand) + v4_summand

Source: Derived from workspace Li, Rinzel, 1994 at changeset d967aac35ade.

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Equations for InsP3 Receptor-mediated [Ca2+]i Oscillations Derived from a Detailed Kinetic Model: A Hodgkin-Huxley Like Formalism