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Gupta, Maurya, Stephens, Dennis, Subramaniam, 2009
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An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis
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Model Mathematics
Component based math viewer is available
Component: environment
Component: main
LPS
=
time
2
if
time
≦
0.5
1
-
time
-
0.5
1.5
if
time
>
0.5
∧
time
<
2
0
otherwise
v_1
=
LPS
PIP_2
k_1
v_2
=
PIP_2
k_2
v_3
=
DG
k_3
v_4
=
AA
k_4
v_5
=
DG
GPCho
k_5
v_6
=
LPS
GPCho
k_6
v_7
=
GPCho
k_7
v_8
=
AA
k_8
v_9
=
HETE
k_9
v_10
=
DG
AA
k_10
v_11
=
LPS
AA
k_11
v_12
=
AA
k_12
v_13
=
PGH_2
k_13
v_14
=
PGE_2
k_14
v_15
=
PGH_2
k_15
v_16
=
PGF_2a
k_16
v_17
=
PGH_2
k_17
v_18
=
PGD_2
k_18
v_19
=
PGD_2
k_19
v_20
=
dPGD_2
k_20
v_21
=
PGJ_2
k_21
v_22
=
dPGJ_2
k_22
d
d
time
AA
=
v_1
+
v_2
+
v_3
-
v_4
+
v_5
+
v_6
+
v_7
-
v_8
-
v_10
-
v_11
-
v_12
d
d
time
HETE
=
v_8
-
v_9
d
d
time
PGH_2
=
v_10
+
v_11
+
v_12
-
v_13
-
v_15
-
v_17
d
d
time
PGE_2
=
v_13
-
v_14
d
d
time
PGF_2a
=
v_15
-
v_16
d
d
time
PGD_2
=
v_17
-
v_18
-
v_19
d
d
time
PGJ_2
=
v_18
-
v_21
d
d
time
dPGD_2
=
v_19
-
v_20
d
d
time
dPGJ_2
=
v_21
-
v_22
Source
Derived from workspace
Gupta, Maurya, Stephens, Dennis and Subramaniam, 2009
at changeset
5d61792c8056
.
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An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis