Current_Ik1.cellml

About this model

Original publication:
 Kernik et al. (2019): "A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources" J Physiol. 2019 Sep 1; 597(17): 4533-4564.
DOI:https://dx.doi.org/10.1113%2FJP277724

Figure 09

Inward rectifier potassium current (IK1) model

Current_Ik1.cellml is the main CellML file which contains the formulation for the inward rectifier potassium current. Its associated SED-ML file contains all the simulation settings.

To execute the code, all the files related to this channel need to be downloaded in a same folder:

  1. fig9_K1.py
  2. Current_Ik1.cellml
  3. Current_Ik1.sedml
  4. parameter_Ik1.cellml
  5. parameter.cellml
  6. gating_Ik1.cellml
  7. unit.cellml

To reproduce Figure 9, save all the files to the same folder and execute the following script from the command line:

$ cd [PathToThisFile]

$ [PathToOpenCOR]/pythonshell fig9_K1.py

figures/Figure9_K1.png

I-V curve.