Mechanistic PK-PD model of alendronate treatment of postmenopausal osteoporosis predicts bone site-specific response: hip

Mechanistic PK-PD model of alendronate treatment of postmenopausal osteoporosis predicts bone site-specific response: hip

About this model

Original publication:

Calvo-Gallego, J. L., Pivonka, P., Ruiz-Lozano, R., & Martínez-Reina, J. (2022). Mechanistic PK-PD model of alendronate treatment of postmenopausal osteoporosis predicts bone site-specific response. Frontiers in bioengineering and biotechnology, 10, 940620.

DOI:

https://doi.org/10.3389/fbioe.2022.940620

Model status

  • The initial values of the parameters of this CellML model have been set to represent the hip as shown in the following table.