Model Mathematics

Component: environment

m=stimMagtR q_LB1_stim=stimHolding+mtime-stimSt+tRiftime<stimSttime>stimSt-tRstimMag+stimHoldingiftimestimSttime<stimSt+stimDurstimHolding+-mtime-stimSt-tR-stimDuriftimestimSt+tR+stimDurtimestimSt+stimDurstimHoldingotherwise v_Rsynthesis=1e-4 ddtimeq_RB1_inactive=-v_Rswitch_B1+0.0v_Rsynthesis ddtimeq_L_RB1_inactive=-v_LRswitch_B1 ddtimeq_LB1_ode=-v_L_B1 ddtimeq_RB1=v_Rswitch_B1-v_C_B1-v_L_B1 ddtimeq_Gs=-v_C_B1-v_R_B1+v_Reassoc_Gs ddtimeq_RB1_Gs=v_C_B1-v_Act1_Gs ddtimeq_L_RB1=v_LRswitch_B1-v_R_B1+v_L_B1 ddtimeq_L_RB1_Gs=v_R_B1-v_Act2_Gs ddtimeq_Gsa_GTP=v_Act1_Gs+v_Act2_Gs-v_Hyd_Gs ddtimeq_Gsbetagamma=v_Act1_Gs+v_Act2_Gs-v_Reassoc_Gs ddtimeq_Gsa_GDP=v_Hyd_Gs-v_Reassoc_Gs ddtimeq_GTP=-v_Act1_Gs-v_Act2_Gs ddtimeq_GDP=v_Act1_Gs+v_Act2_Gs ddtimeq_Pi=v_Hyd_Gs ddtimeq_RB1_tag=v_Act1_Gs-v_InternR_B1 ddtimeq_L_RB1_tag=v_Act2_Gs-v_InternLR_B1 ddtimeq_RB1_GRKArr=v_InternR_B1 ddtimeq_L_RB1_GRKArr=v_InternLR_B1 ddtimeq_GRKArr=-v_InternR_B1-v_InternLR_B1 q_LB1=q_LB1_stim+q_LB1_ode conserv_R_T=q_RB1_inactive+q_L_RB1_inactive+q_RB1+q_RB1_Gs+q_L_RB1+q_L_RB1_Gs+q_RB1_tag+q_L_RB1_tag+q_RB1_GRKArr+q_L_RB1_GRKArr conserv_L_T=q_L_RB1_inactive+q_LB1+q_L_RB1+q_L_RB1_Gs+q_L_RB1_tag+q_L_RB1_GRKArr conserv_G_T=q_Gs+q_RB1_Gs+q_L_RB1_Gs+q_Gsa_GTP+q_Gsa_GDP

Component: GPCR_B1AR_reduced_parameters

Component: GPCR_B1AR_reduced

mu_RB1_inactive=RTlnK_RB1_inactiveq_RB1_inactive mu_L_RB1_inactive=RTlnK_L_RB1_inactiveq_L_RB1_inactive mu_LB1=RTlnK_LB1q_LB1 mu_RB1=RTlnK_RB1q_RB1 mu_Gs=RTlnK_Gsq_Gs mu_RB1_Gs=RTlnK_RB1_Gsq_RB1_Gs mu_L_RB1=RTlnK_L_RB1q_L_RB1 mu_L_RB1_Gs=RTlnK_L_RB1_Gsq_L_RB1_Gs mu_Gsa_GTP=RTlnK_Gsa_GTPq_Gsa_GTP mu_Gsbetagamma=RTlnK_Gsbetagammaq_Gsbetagamma mu_Gsa_GDP=RTlnK_Gsa_GDPq_Gsa_GDP mu_GTP=RTlnK_GTPq_GTP mu_GDP=RTlnK_GDPq_GDP mu_Pi=RTlnK_Piq_Pi mu_RB1_tag=RTlnK_RB1_tagq_RB1_tag mu_L_RB1_tag=RTlnK_L_RB1_tagq_L_RB1_tag mu_RB1_GRKArr=RTlnK_RB1_GRKArrq_RB1_GRKArr mu_L_RB1_GRKArr=RTlnK_L_RB1_GRKArrq_L_RB1_GRKArr mu_GRKArr=RTlnK_GRKArrq_GRKArr v_Rswitch_B1=kappa_Rswitch_B1mu_RB1_inactiveRT-mu_RB1RT v_LRswitch_B1=kappa_LRswitch_B1mu_L_RB1_inactiveRT-mu_L_RB1RT v_C_B1=kappa_C_B1mu_RB1+mu_GsRT-mu_RB1_GsRT v_R_B1=kappa_R_B1mu_L_RB1+mu_GsRT-mu_L_RB1_GsRT v_L_B1=kappa_L_B1mu_RB1+mu_LB1RT-mu_L_RB1RT v_Act1_Gs=kappa_Act1_Gsmu_RB1_Gs+mu_GTPRT-mu_Gsa_GTP+mu_Gsbetagamma+mu_RB1_tag+mu_GDPRT v_Act2_Gs=kappa_Act2_Gsmu_L_RB1_Gs+mu_GTPRT-mu_Gsa_GTP+mu_Gsbetagamma+mu_L_RB1_tag+mu_GDPRT v_Hyd_Gs=kappa_Hyd_Gsmu_Gsa_GTPRT-mu_Gsa_GDP+mu_PiRT v_Reassoc_Gs=kappa_Reassoc_Gsmu_Gsa_GDP+mu_GsbetagammaRT-mu_GsRT v_InternR_B1=kappa_InternR_B1mu_RB1_tag+mu_GRKArrRT-mu_RB1_GRKArrRT v_InternLR_B1=kappa_InternLR_B1mu_L_RB1_tag+mu_GRKArrRT-mu_L_RB1_GRKArrRT

Component: units

Component: constants

Source
Derived from workspace BG_GPCR_B1AR_reduced at changeset a5768d510225.
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