Rendering of the source text
<?xml version='1.0'?>
<!--
This CellML file was generated on 20/08/2019 at 12:42:33 using:
COR (0.9.31.1409)
Copyright 2002-2019 Dr Alan Garny
http://cor.physiol.ox.ac.uk/ - cor@physiol.ox.ac.uk
CellML 1.0 was used to generate this model
http://www.cellml.org/
-->
<model cmeta:id="MyModel1" name="MyModel1" xmlns="http://www.cellml.org/cellml/1.0#" xmlns:cellml="http://www.cellml.org/cellml/1.0#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
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xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:bqs="http://www.cellml.org/bqs/1.0#">
<rdf:Description rdf:about="#MyModel1">
<bqs:reference rdf:parseType="Resource">
<dc:subject rdf:parseType="Resource">
<bqs:subject_type>keyword</bqs:subject_type>
<rdf:value>
<rdf:Bag>
<rdf:li>electrophysiology</rdf:li>
</rdf:Bag>
</rdf:value>
</dc:subject>
</bqs:reference>
</rdf:Description>
</rdf:RDF>
<units name="millisecond">
<unit prefix="milli" units="second"/>
</units>
<units name="per_millisecond">
<unit exponent="-1" units="millisecond"/>
</units>
<units name="millivolt">
<unit prefix="milli" units="volt"/>
</units>
<units name="millivolt_per_millimole">
<unit prefix="milli" units="volt"/>
<unit exponent="-1" units="millimolar"/>
</units>
<units name="per_millivolt">
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</units>
<units name="per_millivolt_millisecond">
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<unit exponent="-1" units="millisecond"/>
</units>
<units name="millimolar">
<unit prefix="milli" units="mole"/>
<unit exponent="-1" units="litre"/>
</units>
<units name="per_millimolar">
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<units name="millimolar_per_millisecond">
<unit units="millimolar"/>
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<units name="per_millimolar_per_millisecond">
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<unit exponent="-1" units="millisecond"/>
</units>
<units name="millisecond_per_millimolar">
<unit units="millisecond"/>
<unit exponent="-1" units="millimolar"/>
</units>
<units name="picoA">
<unit prefix="pico" units="ampere"/>
</units>
<units name="microA_per_microF">
<unit prefix="micro" units="ampere"/>
<unit exponent="-1" prefix="micro" units="farad"/>
</units>
<units name="milliS_per_microF">
<unit prefix="milli" units="siemens"/>
<unit exponent="-1" prefix="micro" units="farad"/>
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<units name="microF">
<unit prefix="micro" units="farad"/>
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<units name="micrometre_3">
<unit exponent="3" prefix="micro" units="metre"/>
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<units name="per_micrometre_3">
<unit exponent="-3" prefix="micro" units="metre"/>
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<units name="mm2">
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<units name="centimeter">
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<units name="centimeter_squared">
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<units name="microliter_per_centimeter_cubed">
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<unit exponent="-3" units="centimeter"/>
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<units name="microF_per_centimeter_squared">
<unit units="microF"/>
<unit exponent="-1" units="centimeter_squared"/>
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<units name="microliter">
<unit prefix="micro" units="liter"/>
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<units name="joule_per_kilomole_kelvin">
<unit units="joule"/>
<unit exponent="-1" prefix="kilo" units="mole"/>
<unit exponent="-1" units="kelvin"/>
</units>
<units name="coulomb_per_mole">
<unit units="coulomb"/>
<unit exponent="-1" units="mole"/>
</units>
<component name="environment">
<variable name="time" public_interface="out" units="millisecond"/>
</component>
<component name="extracellular">
<variable initial_value="140" name="nao" public_interface="out" units="millimolar"/>
<variable initial_value="1.8" name="cao" public_interface="out" units="millimolar"/>
<variable initial_value="5.4" name="ko" public_interface="out" units="millimolar"/>
</component>
<component name="physical_constants">
<variable initial_value="8314" name="R" public_interface="out" units="joule_per_kilomole_kelvin"/>
<variable initial_value="310" name="T" public_interface="out" units="kelvin"/>
<variable initial_value="96485" name="F" public_interface="out" units="coulomb_per_mole"/>
<variable initial_value="1" name="zna" public_interface="out" units="dimensionless"/>
<variable initial_value="2" name="zca" public_interface="out" units="dimensionless"/>
<variable initial_value="1" name="zk" public_interface="out" units="dimensionless"/>
</component>
<component name="cell_geometry">
<variable initial_value="0.0164" name="L" units="centimeter"/>
<variable initial_value="0.00175" name="rad" units="centimeter"/>
<variable initial_value="3.14159265" name="greekpi" units="dimensionless"/>
<variable name="vcell" public_interface="out" units="microliter"/>
<variable name="Ageo" public_interface="out" units="centimeter_squared"/>
<variable name="Acap" public_interface="out" units="centimeter_squared"/>
<variable name="vmyo" public_interface="out" units="microliter"/>
<variable name="vnsr" public_interface="out" units="microliter"/>
<variable name="vjsr" public_interface="out" units="microliter"/>
<variable name="vcsr" public_interface="out" units="microliter"/>
<variable name="vsl" public_interface="out" units="microliter"/>
<variable name="vss" public_interface="out" units="microliter"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>vcell</ci>
<apply>
<times/>
<cn cellml:units="microliter_per_centimeter_cubed">1000</cn>
<cn cellml:units="dimensionless">3.14159265</cn>
<ci>rad</ci>
<ci>rad</ci>
<ci>L</ci>
</apply>
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<apply>
<eq/>
<ci>Ageo</ci>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>greekpi</ci>
<ci>rad</ci>
<ci>rad</ci>
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<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>greekpi</ci>
<ci>rad</ci>
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</apply>
</apply>
<apply>
<eq/>
<ci>Acap</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>Ageo</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>vmyo</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.6</cn>
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</apply>
</apply>
<apply>
<eq/>
<ci>vnsr</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.04</cn>
<ci>vcell</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>vjsr</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.002</cn>
<ci>vcell</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>vcsr</ci>
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<times/>
<cn cellml:units="dimensionless">0.008</cn>
<ci>vcell</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>vss</ci>
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<times/>
<cn cellml:units="dimensionless">0.02</cn>
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</apply>
<apply>
<eq/>
<ci>vsl</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.15</cn>
<ci>vcell</ci>
</apply>
</apply>
</math>
</component>
<component name="membrane">
<variable initial_value="-86.6814002878592" name="v" public_interface="out" units="millivolt"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="R" public_interface="in" units="joule_per_kilomole_kelvin"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="F" public_interface="in" units="coulomb_per_mole"/>
<variable name="vffrt" public_interface="out" units="coulomb_per_mole"/>
<variable name="vfrt" public_interface="out" units="dimensionless"/>
<variable name="INa" public_interface="in" units="microA_per_microF"/>
<variable name="INaL" public_interface="in" units="microA_per_microF"/>
<variable name="Ito" public_interface="in" units="microA_per_microF"/>
<variable name="Isus" public_interface="in" units="microA_per_microF"/>
<variable name="ICaL" public_interface="in" units="microA_per_microF"/>
<variable name="ICaT" public_interface="in" units="microA_per_microF"/>
<variable name="ICaNa" public_interface="in" units="microA_per_microF"/>
<variable name="ICaK" public_interface="in" units="microA_per_microF"/>
<variable name="IKr" public_interface="in" units="microA_per_microF"/>
<variable name="IKs" public_interface="in" units="microA_per_microF"/>
<variable name="If" public_interface="in" units="microA_per_microF"/>
<variable name="IK1" public_interface="in" units="microA_per_microF"/>
<variable name="INaCa_i" public_interface="in" units="microA_per_microF"/>
<variable name="INaCa_ss" public_interface="in" units="microA_per_microF"/>
<variable name="INaK" public_interface="in" units="microA_per_microF"/>
<variable name="INab" public_interface="in" units="microA_per_microF"/>
<variable name="IpCa" public_interface="in" units="microA_per_microF"/>
<variable name="ICab" public_interface="in" units="microA_per_microF"/>
<variable name="Istim" public_interface="out" units="microA_per_microF"/>
<variable initial_value="-40" name="amp" units="microA_per_microF"/>
<variable initial_value="1" name="duration" units="millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Istim</ci>
<piecewise>
<piece>
<ci>amp</ci>
<apply>
<leq/>
<ci>time</ci>
<ci>duration</ci>
</apply>
</piece>
<otherwise>
<cn cellml:units="microA_per_microF">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>vffrt</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>v</ci>
<ci>F</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>vfrt</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>v</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>v</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<ci>INa</ci>
<ci>INaL</ci>
<ci>Ito</ci>
<ci>Isus</ci>
<ci>ICaL</ci>
<ci>ICaT</ci>
<ci>ICaNa</ci>
<ci>ICaK</ci>
<ci>IKr</ci>
<ci>IKs</ci>
<ci>If</ci>
<ci>IK1</ci>
<ci>INaCa_i</ci>
<ci>INaCa_ss</ci>
<ci>INaK</ci>
<ci>INab</ci>
<ci>IpCa</ci>
<ci>ICab</ci>
<ci>Istim</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="CaMK">
<variable initial_value="0.15" name="KmCaMK" public_interface="out" units="millimolar"/>
<variable initial_value="0.05" name="aCaMK" units="per_millimolar_per_millisecond"/>
<variable initial_value="0.00068" name="bCaMK" units="per_millisecond"/>
<variable initial_value="0.05" name="CaMKo" units="dimensionless"/>
<variable initial_value="0.0015" name="KmCaM" units="millimolar"/>
<variable name="CaMKb" public_interface="out" units="millimolar"/>
<variable name="CaMKa" public_interface="out" units="millimolar"/>
<variable initial_value="0.00505983330678751" name="CaMKt" units="millimolar"/>
<variable name="cass" public_interface="in" units="millimolar"/>
<variable name="time" public_interface="in" units="millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>CaMKb</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>CaMKo</ci>
<apply>
<minus/>
<cn cellml:units="millimolar">1</cn>
<ci>CaMKt</ci>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>KmCaM</ci>
<ci>cass</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>CaMKa</ci>
<apply>
<plus/>
<ci>CaMKb</ci>
<ci>CaMKt</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>CaMKt</ci>
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<apply>
<minus/>
<apply>
<times/>
<ci>aCaMK</ci>
<ci>CaMKb</ci>
<apply>
<plus/>
<ci>CaMKb</ci>
<ci>CaMKt</ci>
</apply>
</apply>
<apply>
<times/>
<ci>bCaMK</ci>
<ci>CaMKt</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="intracellular_ions">
<variable initial_value="0.019975" name="BSRmax" units="millimolar"/>
<variable initial_value="0.00087" name="KmBSR" units="millimolar"/>
<variable initial_value="0.4777" name="BSLmax" units="millimolar"/>
<variable initial_value="0.0087" name="KmBSL" units="millimolar"/>
<variable initial_value="2.88" name="csqnmax" units="millimolar"/>
<variable initial_value="0.8" name="kmcsqn" units="millimolar"/>
<variable initial_value="1.2" name="csqnmaxsl" units="millimolar"/>
<variable initial_value="0.1125" name="cmdnmax" units="millimolar"/>
<variable initial_value="0.00238" name="kmcmdn" units="millimolar"/>
<variable initial_value="0.0125" name="cmdnmaxsl" units="millimolar"/>
<variable initial_value="0.0315" name="trpnmax" units="millimolar"/>
<variable initial_value="0.0005" name="kmtrpn" units="millimolar"/>
<variable initial_value="0.0035" name="trpnmaxsl" units="millimolar"/>
<variable initial_value="8.23183964616932" name="nai" public_interface="out" units="millimolar"/>
<variable initial_value="8.23153516580562" name="nasl" public_interface="out" units="millimolar"/>
<variable initial_value="8.23154325237268" name="nass" public_interface="out" units="millimolar"/>
<variable initial_value="143.767359809132" name="ki" public_interface="out" units="millimolar"/>
<variable initial_value="143.767768218104" name="kss" public_interface="out" units="millimolar"/>
<variable initial_value="143.767769906216" name="ksl" public_interface="out" units="millimolar"/>
<variable initial_value="4.36004404734282e-5" name="cai" public_interface="out" units="millimolar"/>
<variable initial_value="0.000101777993438818" name="cass" public_interface="out" units="millimolar"/>
<variable initial_value="0.000102004317781147" name="casl" public_interface="out" units="millimolar"/>
<variable initial_value="1.26350902016858" name="cansr" public_interface="out" units="millimolar"/>
<variable initial_value="1.24811940209535" name="cajsr" public_interface="out" units="millimolar"/>
<variable initial_value="1.26516959198518" name="cacsr" public_interface="out" units="millimolar"/>
<variable name="Acap" public_interface="in" units="centimeter_squared"/>
<variable name="R" public_interface="in" units="joule_per_kilomole_kelvin"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="F" public_interface="in" units="coulomb_per_mole"/>
<variable name="INa" public_interface="in" units="microA_per_microF"/>
<variable name="INaL" public_interface="in" units="microA_per_microF"/>
<variable name="INaCa_i" public_interface="in" units="microA_per_microF"/>
<variable name="INaCa_ss" public_interface="in" units="microA_per_microF"/>
<variable name="ICaNa" public_interface="in" units="microA_per_microF"/>
<variable name="INaK" public_interface="in" units="microA_per_microF"/>
<variable name="INab" public_interface="in" units="microA_per_microF"/>
<variable name="IfNa" public_interface="in" units="microA_per_microF"/>
<variable name="IfK" public_interface="in" units="microA_per_microF"/>
<variable name="IK1" public_interface="in" units="microA_per_microF"/>
<variable name="IKr" public_interface="in" units="microA_per_microF"/>
<variable name="IKs" public_interface="in" units="microA_per_microF"/>
<variable name="Istim" public_interface="in" units="microA_per_microF"/>
<variable name="Ito" public_interface="in" units="microA_per_microF"/>
<variable name="Isus" public_interface="in" units="microA_per_microF"/>
<variable name="ICab" public_interface="in" units="microA_per_microF"/>
<variable name="IpCa" public_interface="in" units="microA_per_microF"/>
<variable name="ICaL" public_interface="in" units="microA_per_microF"/>
<variable name="ICaT" public_interface="in" units="microA_per_microF"/>
<variable name="JdiffNa" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="JgapNa" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jdiff" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jgap" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="JdiffK" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="JgapK" public_interface="in" units="millimolar_per_millisecond"/>
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<variable name="Jrel1" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jrel2" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jip3" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jtr1" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jtr2" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="ICaK" public_interface="in" units="microA_per_microF"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="vmyo" public_interface="in" units="microliter"/>
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<variable name="vss" public_interface="in" units="microliter"/>
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<variable name="vjsr" public_interface="in" units="microliter"/>
<variable name="vcsr" public_interface="in" units="microliter"/>
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<variable name="Bcacsr" units="dimensionless"/>
<variable name="Bcass" units="dimensionless"/>
<variable name="Bcasl" units="dimensionless"/>
<variable initial_value="1" name="cm" public_interface="out" units="microF_per_centimeter_squared"/>
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<plus/>
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<times/>
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<times/>
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<ci>INaCa_ss</ci>
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<variable name="EKs" public_interface="out" units="millivolt"/>
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<variable name="casl" public_interface="in" units="millimolar"/>
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<variable name="tm" public_interface="out" units="millisecond"/>
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<minus/>
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<ci>ths</ci>
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<variable name="mLss" units="dimensionless"/>
<variable name="tm" public_interface="in" units="millisecond"/>
<variable name="tmL" units="millisecond"/>
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<variable name="hLss" units="dimensionless"/>
<variable name="v" public_interface="in" units="millivolt"/>
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<variable name="hLssp" units="dimensionless"/>
<variable name="thLp" units="millisecond"/>
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<variable name="fINaLp" units="dimensionless"/>
<variable name="KmCaMK" public_interface="in" units="millimolar"/>
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<variable name="INaL" public_interface="out" units="microA_per_microF"/>
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<ci>mLss</ci>
<ci>mL</ci>
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<ci>thL</ci>
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<ci>hLssp</ci>
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<ci>thLp</ci>
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<ci>thL</ci>
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<ci>thLp</ci>
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<ci>CaMKa</ci>
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<minus/>
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<ci>mL</ci>
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<plus/>
<apply>
<times/>
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<minus/>
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<ci>fINaLp</ci>
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<ci>hL</ci>
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<ci>fINaLp</ci>
<ci>hLp</ci>
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<component name="Ito">
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="EK" public_interface="in" units="millivolt"/>
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<variable name="taua" units="millisecond"/>
<variable name="iss" units="dimensionless"/>
<variable name="tauis" units="millisecond"/>
<variable name="tauif" units="millisecond"/>
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<variable initial_value="0.192" name="Gto" units="milliS_per_microF"/>
<variable name="Ito" public_interface="out" units="microA_per_microF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
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<ci>v</ci>
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<cn cellml:units="millivolt">27</cn>
<ci>v</ci>
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<apply>
<minus/>
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<divide/>
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<minus/>
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<plus/>
<ci>v</ci>
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<divide/>
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<plus/>
<ci>v</ci>
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<plus/>
<cn cellml:units="millisecond">6.162</cn>
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<divide/>
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<apply>
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<cn cellml:units="dimensionless">0.3933</cn>
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<exp/>
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<divide/>
<apply>
<minus/>
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<plus/>
<ci>v</ci>
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<cn cellml:units="dimensionless">100</cn>
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<cn cellml:units="dimensionless">0.08004</cn>
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<divide/>
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<minus/>
<ci>v</ci>
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<diff/>
<bvar>
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<ci>ass</ci>
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<apply>
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<ci>v</ci>
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<component name="Isus">
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<variable name="asus" units="dimensionless"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="EK" public_interface="in" units="millivolt"/>
<variable name="Isus" public_interface="out" units="microA_per_microF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
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<ci>asus</ci>
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<ci>v</ci>
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<times/>
<ci>Gsus</ci>
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<minus/>
<ci>v</ci>
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<ci>v</ci>
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<times/>
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<plus/>
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<plus/>
<ci>v</ci>
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<ci>tfs</ci>
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<apply>
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<divide/>
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<minus/>
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<plus/>
<ci>v</ci>
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<divide/>
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<plus/>
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<ci>Aff</ci>
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<eq/>
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<minus/>
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<ci>Aff</ci>
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<ci>fss</ci>
<ci>fs</ci>
</apply>
<ci>tfs</ci>
</apply>
</apply>
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<eq/>
<ci>f</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Aff</ci>
<ci>ff</ci>
</apply>
<apply>
<times/>
<ci>Afs</ci>
<ci>fs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>fcass</ci>
<ci>fss</ci>
</apply>
<apply>
<eq/>
<ci>tfcaf</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.72</cn>
<apply>
<plus/>
<cn cellml:units="millisecond">7</cn>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.04</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">15.19</cn>
</apply>
<cn cellml:units="millivolt">4</cn>
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</apply>
<cn cellml:units="millivolt">7</cn>
</apply>
</apply>
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<apply>
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<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">15.19</cn>
</apply>
<cn cellml:units="millivolt">4</cn>
</apply>
<cn cellml:units="millivolt">7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
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<apply>
<eq/>
<ci>tfcas</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.49</cn>
<apply>
<plus/>
<cn cellml:units="millisecond">100</cn>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.00012</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">15.19</cn>
</apply>
</apply>
<cn cellml:units="millivolt">3</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.00012</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">15.19</cn>
</apply>
<cn cellml:units="millivolt">7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Afcaf</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">0.3</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.6</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>v</ci>
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</apply>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Afcas</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>Afcaf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fcaf</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fcass</ci>
<ci>fcaf</ci>
</apply>
<ci>tfcaf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fcas</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fcass</ci>
<ci>fcas</ci>
</apply>
<ci>tfcas</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fca</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Afcaf</ci>
<ci>fcaf</ci>
</apply>
<apply>
<times/>
<ci>Afcas</ci>
<ci>fcas</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tjca</ci>
<cn cellml:units="millisecond">75</cn>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>jca</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fcass</ci>
<ci>jca</ci>
</apply>
<ci>tjca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>tffp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2.5</cn>
<ci>tff</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>ffp</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fss</ci>
<ci>ffp</ci>
</apply>
<ci>tffp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fp</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Aff</ci>
<ci>ffp</ci>
</apply>
<apply>
<times/>
<ci>Afs</ci>
<ci>fs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tfcafp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2.5</cn>
<ci>tfcaf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fcafp</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fcass</ci>
<ci>fcafp</ci>
</apply>
<ci>tfcafp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fcap</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Afcaf</ci>
<ci>fcafp</ci>
</apply>
<apply>
<times/>
<ci>Afcas</ci>
<ci>fcas</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>km2n</ci>
<apply>
<times/>
<ci>jca</ci>
<cn cellml:units="per_millisecond">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>anca</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<apply>
<divide/>
<ci>k2n</ci>
<ci>km2n</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>Kmn</ci>
<ci>cass</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">4</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>nca</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>anca</ci>
<ci>k2n</ci>
</apply>
<apply>
<times/>
<ci>nca</ci>
<ci>km2n</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>PhiCaL</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt">4</cn>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>cass</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vfrt</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="per_millimolar">0.341</cn>
<ci>cao</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vfrt</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>PhiCaNa</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>nass</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vfrt</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>nao</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vfrt</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>PhiCaK</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>kss</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vfrt</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>ko</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vfrt</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>PCap</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1.1</cn>
<ci>PCa</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>PCaNa</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.00125</cn>
<ci>PCa</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>PCaK</ci>
<apply>
<times/>
<cn cellml:units="dimensionless" type="e-notation">3.574<sep/>-4</cn>
<ci>PCa</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>PCaNap</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.00125</cn>
<ci>PCap</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>PCaKp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless" type="e-notation">3.574<sep/>-4</cn>
<ci>PCap</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fICaLp</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>KmCaMK</ci>
<ci>CaMKa</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL</ci>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fICaLp</ci>
</apply>
<ci>PCa</ci>
<ci>PhiCaL</ci>
<ci>d</ci>
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<plus/>
<apply>
<times/>
<ci>f</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
</apply>
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<times/>
<ci>jca</ci>
<ci>fca</ci>
<ci>nca</ci>
</apply>
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<times/>
<ci>fICaLp</ci>
<ci>PCap</ci>
<ci>PhiCaL</ci>
<ci>d</ci>
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<plus/>
<apply>
<times/>
<ci>fp</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
</apply>
</apply>
<apply>
<times/>
<ci>jca</ci>
<ci>fcap</ci>
<ci>nca</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaNa</ci>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fICaLp</ci>
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<ci>PCaNa</ci>
<ci>PhiCaNa</ci>
<ci>d</ci>
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<plus/>
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<times/>
<ci>f</ci>
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<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
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<times/>
<ci>jca</ci>
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<ci>nca</ci>
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<times/>
<ci>fICaLp</ci>
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<ci>PhiCaNa</ci>
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<plus/>
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<times/>
<ci>fp</ci>
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<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
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<times/>
<ci>jca</ci>
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<ci>ICaK</ci>
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<plus/>
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<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fICaLp</ci>
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<ci>PCaK</ci>
<ci>PhiCaK</ci>
<ci>d</ci>
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<plus/>
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<times/>
<ci>f</ci>
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<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
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<times/>
<ci>jca</ci>
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<ci>nca</ci>
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<times/>
<ci>fICaLp</ci>
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<ci>PhiCaK</ci>
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<plus/>
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<times/>
<ci>fp</ci>
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<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
</apply>
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<times/>
<ci>jca</ci>
<ci>fcap</ci>
<ci>nca</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ICaT">
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<variable name="bss" units="dimensionless"/>
<variable name="gss" units="dimensionless"/>
<variable name="taub" units="millisecond"/>
<variable name="taug" units="millisecond"/>
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<variable initial_value="0.994214357917907" name="g" units="dimensionless"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="ECa" public_interface="in" units="millivolt"/>
<variable name="ICaT" public_interface="out" units="microA_per_microF"/>
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<minus/>
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<plus/>
<ci>v</ci>
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<ci>gss</ci>
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<divide/>
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<plus/>
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<divide/>
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<plus/>
<ci>v</ci>
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<cn cellml:units="millivolt">5</cn>
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<eq/>
<ci>taub</ci>
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<divide/>
<cn cellml:units="millisecond">1</cn>
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<plus/>
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<times/>
<cn cellml:units="dimensionless">1.068</cn>
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<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
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<cn cellml:units="millivolt">30</cn>
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<times/>
<cn cellml:units="dimensionless">1.068</cn>
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<divide/>
<apply>
<minus/>
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<plus/>
<ci>v</ci>
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<ci>taug</ci>
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<divide/>
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<plus/>
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<times/>
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<divide/>
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<plus/>
<ci>v</ci>
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<plus/>
<ci>v</ci>
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<diff/>
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<minus/>
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<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>g</ci>
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<divide/>
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<minus/>
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<eq/>
<ci>ICaT</ci>
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<times/>
<ci>GCaT</ci>
<ci>b</ci>
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<minus/>
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</apply>
</apply>
</math>
</component>
<component name="IKr">
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<variable name="xrss" units="dimensionless"/>
<variable name="txrf" units="millisecond"/>
<variable name="txrs" units="millisecond"/>
<variable name="Axrf" units="dimensionless"/>
<variable name="Axrs" units="dimensionless"/>
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<variable initial_value="0.568716473334161" name="xrs" units="dimensionless"/>
<variable name="xr" units="dimensionless"/>
<variable name="rkr" units="dimensionless"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="EK" public_interface="in" units="millivolt"/>
<variable name="ko" public_interface="in" units="millimolar"/>
<variable name="IKr" public_interface="out" units="microA_per_microF"/>
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<ci>xrss</ci>
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<plus/>
<ci>v</ci>
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<ci>txrf</ci>
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<cn cellml:units="millisecond">1</cn>
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<times/>
<cn cellml:units="dimensionless">0.3652</cn>
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<divide/>
<apply>
<minus/>
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<plus/>
<ci>v</ci>
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<cn cellml:units="millivolt">3.869</cn>
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<divide/>
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<divide/>
<apply>
<minus/>
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<plus/>
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<minus/>
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<ci>Axrf</ci>
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<times/>
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<root/>
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<apply>
<minus/>
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<cn cellml:units="millivolt">230</cn>
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<divide/>
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<plus/>
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<plus/>
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<ci>IKs</ci>
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<times/>
<ci>GKs</ci>
<ci>KsCa</ci>
<ci>xs1</ci>
<ci>xs2</ci>
<apply>
<minus/>
<ci>v</ci>
<ci>EKs</ci>
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<minus/>
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<plus/>
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<times/>
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<plus/>
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<minus/>
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<plus/>
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<times/>
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<cn cellml:units="millivolt">3.8115</cn>
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<minus/>
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<plus/>
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<minus/>
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<ci>qna</ci>
<ci>v</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h1_i</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nasl</ci>
<ci>kna3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<ci>hna</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h2_i</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nasl</ci>
<ci>hna</ci>
</apply>
<apply>
<times/>
<ci>kna3</ci>
<ci>h1_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h3_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h1_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h4_i</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nasl</ci>
<ci>kna1</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nasl</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h5_i</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nasl</ci>
<ci>nasl</ci>
</apply>
<apply>
<times/>
<ci>h4_i</ci>
<ci>kna1</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h6_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h4_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h7_i</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>hna</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h8_i</ci>
<apply>
<divide/>
<ci>nao</ci>
<apply>
<times/>
<ci>kna3</ci>
<ci>hna</ci>
<ci>h7_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h9_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h7_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h10_i</ci>
<apply>
<plus/>
<ci>kasymm</ci>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna1</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h11_i</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nao</ci>
<ci>nao</ci>
</apply>
<apply>
<times/>
<ci>h10_i</ci>
<ci>kna1</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h12_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h10_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k1_i</ci>
<apply>
<times/>
<ci>h12_i</ci>
<ci>cao</ci>
<ci>kcaon</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k2_i</ci>
<ci>kcaoff</ci>
</apply>
<apply>
<eq/>
<ci>k3p_i</ci>
<apply>
<times/>
<ci>h9_i</ci>
<ci>wca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k3pp_i</ci>
<apply>
<times/>
<ci>h8_i</ci>
<ci>wnaca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k3_i</ci>
<apply>
<plus/>
<ci>k3p_i</ci>
<ci>k3pp_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4p_i</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>h3_i</ci>
<ci>wca</ci>
</apply>
<ci>hca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4pp_i</ci>
<apply>
<times/>
<ci>h2_i</ci>
<ci>wnaca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4_i</ci>
<apply>
<plus/>
<ci>k4p_i</ci>
<ci>k4pp_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k5_i</ci>
<ci>kcaoff</ci>
</apply>
<apply>
<eq/>
<ci>k6_i</ci>
<apply>
<times/>
<ci>h6_i</ci>
<ci>casl</ci>
<ci>kcaon</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k7_i</ci>
<apply>
<times/>
<ci>h5_i</ci>
<ci>h2_i</ci>
<ci>wna</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k8_i</ci>
<apply>
<times/>
<ci>h8_i</ci>
<ci>h11_i</ci>
<ci>wna</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>x1_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k2_i</ci>
<ci>k4_i</ci>
<apply>
<plus/>
<ci>k7_i</ci>
<ci>k6_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k5_i</ci>
<ci>k7_i</ci>
<apply>
<plus/>
<ci>k2_i</ci>
<ci>k3_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x2_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k1_i</ci>
<ci>k7_i</ci>
<apply>
<plus/>
<ci>k4_i</ci>
<ci>k5_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k4_i</ci>
<ci>k6_i</ci>
<apply>
<plus/>
<ci>k1_i</ci>
<ci>k8_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x3_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k1_i</ci>
<ci>k3_i</ci>
<apply>
<plus/>
<ci>k7_i</ci>
<ci>k6_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k8_i</ci>
<ci>k6_i</ci>
<apply>
<plus/>
<ci>k2_i</ci>
<ci>k3_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x4_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k2_i</ci>
<ci>k8_i</ci>
<apply>
<plus/>
<ci>k4_i</ci>
<ci>k5_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k3_i</ci>
<ci>k5_i</ci>
<apply>
<plus/>
<ci>k1_i</ci>
<ci>k8_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E1_i</ci>
<apply>
<divide/>
<ci>x1_i</ci>
<apply>
<plus/>
<ci>x1_i</ci>
<ci>x2_i</ci>
<ci>x3_i</ci>
<ci>x4_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E2_i</ci>
<apply>
<divide/>
<ci>x2_i</ci>
<apply>
<plus/>
<ci>x1_i</ci>
<ci>x2_i</ci>
<ci>x3_i</ci>
<ci>x4_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E3_i</ci>
<apply>
<divide/>
<ci>x3_i</ci>
<apply>
<plus/>
<ci>x1_i</ci>
<ci>x2_i</ci>
<ci>x3_i</ci>
<ci>x4_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E4_i</ci>
<apply>
<divide/>
<ci>x4_i</ci>
<apply>
<plus/>
<ci>x1_i</ci>
<ci>x2_i</ci>
<ci>x3_i</ci>
<ci>x4_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>allo_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>KmCaAct</ci>
<ci>casl</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JncxNa_i</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<apply>
<minus/>
<apply>
<times/>
<ci>E4_i</ci>
<ci>k7_i</ci>
</apply>
<apply>
<times/>
<ci>E1_i</ci>
<ci>k8_i</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>E3_i</ci>
<ci>k4pp_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>E2_i</ci>
<ci>k3pp_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JncxCa_i</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>E2_i</ci>
<ci>k2_i</ci>
</apply>
<apply>
<times/>
<ci>E1_i</ci>
<ci>k1_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INaCa_i</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.8</cn>
<ci>Gncx</ci>
<ci>allo_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>zna</ci>
<ci>JncxNa_i</ci>
</apply>
<apply>
<times/>
<ci>zca</ci>
<ci>JncxCa_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h1_ss</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nass</ci>
<ci>kna3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<ci>hna</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h2_ss</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nass</ci>
<ci>hna</ci>
</apply>
<apply>
<times/>
<ci>kna3</ci>
<ci>h1_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h3_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h1_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h4_ss</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nass</ci>
<ci>kna1</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nass</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h5_ss</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nass</ci>
<ci>nass</ci>
</apply>
<apply>
<times/>
<ci>h4_ss</ci>
<ci>kna1</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h6_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h4_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h7_ss</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>hna</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h8_ss</ci>
<apply>
<divide/>
<ci>nao</ci>
<apply>
<times/>
<ci>kna3</ci>
<ci>hna</ci>
<ci>h7_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h9_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h7_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h10_ss</ci>
<apply>
<plus/>
<ci>kasymm</ci>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna1</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h11_ss</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nao</ci>
<ci>nao</ci>
</apply>
<apply>
<times/>
<ci>h10_ss</ci>
<ci>kna1</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h12_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h10_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k1_ss</ci>
<apply>
<times/>
<ci>h12_ss</ci>
<ci>cao</ci>
<ci>kcaon</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k2_ss</ci>
<ci>kcaoff</ci>
</apply>
<apply>
<eq/>
<ci>k3p_ss</ci>
<apply>
<times/>
<ci>h9_ss</ci>
<ci>wca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k3pp_ss</ci>
<apply>
<times/>
<ci>h8_ss</ci>
<ci>wnaca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k3_ss</ci>
<apply>
<plus/>
<ci>k3p_ss</ci>
<ci>k3pp_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4p_ss</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>h3_ss</ci>
<ci>wca</ci>
</apply>
<ci>hca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4pp_ss</ci>
<apply>
<times/>
<ci>h2_ss</ci>
<ci>wnaca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4_ss</ci>
<apply>
<plus/>
<ci>k4p_ss</ci>
<ci>k4pp_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k5_ss</ci>
<ci>kcaoff</ci>
</apply>
<apply>
<eq/>
<ci>k6_ss</ci>
<apply>
<times/>
<ci>h6_ss</ci>
<ci>cass</ci>
<ci>kcaon</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k7_ss</ci>
<apply>
<times/>
<ci>h5_ss</ci>
<ci>h2_ss</ci>
<ci>wna</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k8_ss</ci>
<apply>
<times/>
<ci>h8_ss</ci>
<ci>h11_ss</ci>
<ci>wna</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>x1_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k2_ss</ci>
<ci>k4_ss</ci>
<apply>
<plus/>
<ci>k7_ss</ci>
<ci>k6_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k5_ss</ci>
<ci>k7_ss</ci>
<apply>
<plus/>
<ci>k2_ss</ci>
<ci>k3_ss</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x2_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k1_ss</ci>
<ci>k7_ss</ci>
<apply>
<plus/>
<ci>k4_ss</ci>
<ci>k5_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k4_ss</ci>
<ci>k6_ss</ci>
<apply>
<plus/>
<ci>k1_ss</ci>
<ci>k8_ss</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x3_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k1_ss</ci>
<ci>k3_ss</ci>
<apply>
<plus/>
<ci>k7_ss</ci>
<ci>k6_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k8_ss</ci>
<ci>k6_ss</ci>
<apply>
<plus/>
<ci>k2_ss</ci>
<ci>k3_ss</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x4_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k2_ss</ci>
<ci>k8_ss</ci>
<apply>
<plus/>
<ci>k4_ss</ci>
<ci>k5_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k3_ss</ci>
<ci>k5_ss</ci>
<apply>
<plus/>
<ci>k1_ss</ci>
<ci>k8_ss</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E1_ss</ci>
<apply>
<divide/>
<ci>x1_ss</ci>
<apply>
<plus/>
<ci>x1_ss</ci>
<ci>x2_ss</ci>
<ci>x3_ss</ci>
<ci>x4_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E2_ss</ci>
<apply>
<divide/>
<ci>x2_ss</ci>
<apply>
<plus/>
<ci>x1_ss</ci>
<ci>x2_ss</ci>
<ci>x3_ss</ci>
<ci>x4_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E3_ss</ci>
<apply>
<divide/>
<ci>x3_ss</ci>
<apply>
<plus/>
<ci>x1_ss</ci>
<ci>x2_ss</ci>
<ci>x3_ss</ci>
<ci>x4_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E4_ss</ci>
<apply>
<divide/>
<ci>x4_ss</ci>
<apply>
<plus/>
<ci>x1_ss</ci>
<ci>x2_ss</ci>
<ci>x3_ss</ci>
<ci>x4_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>allo_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>KmCaAct</ci>
<ci>cass</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JncxNa_ss</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<apply>
<minus/>
<apply>
<times/>
<ci>E4_ss</ci>
<ci>k7_ss</ci>
</apply>
<apply>
<times/>
<ci>E1_ss</ci>
<ci>k8_ss</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>E3_ss</ci>
<ci>k4pp_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>E2_ss</ci>
<ci>k3pp_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JncxCa_ss</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>E2_ss</ci>
<ci>k2_ss</ci>
</apply>
<apply>
<times/>
<ci>E1_ss</ci>
<ci>k1_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INaCa_ss</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.2</cn>
<ci>Gncx</ci>
<ci>allo_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>zna</ci>
<ci>JncxNa_ss</ci>
</apply>
<apply>
<times/>
<ci>zca</ci>
<ci>JncxCa_ss</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="INaK">
<variable initial_value="949.5" name="k1p" units="per_millisecond"/>
<variable initial_value="182.4" name="k1m" units="per_millisecond"/>
<variable initial_value="687.2" name="k2p" units="per_millisecond"/>
<variable initial_value="39.4" name="k2m" units="per_millisecond"/>
<variable initial_value="1899" name="k3p" units="per_millisecond"/>
<variable initial_value="79300" name="k3m" units="per_millisecond"/>
<variable initial_value="639" name="k4p" units="per_millisecond"/>
<variable initial_value="40" name="k4m" units="per_millisecond"/>
<variable initial_value="9.073" name="Knai0" units="millimolar"/>
<variable initial_value="27.78" name="Knao0" units="millimolar"/>
<variable initial_value="-0.155" name="delta" units="millivolt"/>
<variable initial_value="0.5" name="Kki" units="per_millisecond"/>
<variable initial_value="0.3582" name="Kko" units="per_millisecond"/>
<variable initial_value="0.05" name="MgADP" units="millimolar"/>
<variable initial_value="9.8" name="MgATP" units="millimolar"/>
<variable initial_value="1.698e-7" name="Kmgatp" units="millimolar"/>
<variable initial_value="1e-7" name="H" units="millimolar"/>
<variable initial_value="4.2" name="eP" units="dimensionless"/>
<variable initial_value="1.698e-7" name="Khp" units="millimolar"/>
<variable initial_value="224" name="Knap" units="millimolar"/>
<variable initial_value="292" name="Kxkur" units="millimolar"/>
<variable name="zk" public_interface="in" units="dimensionless"/>
<variable name="zna" public_interface="in" units="dimensionless"/>
<variable initial_value="32.4872" name="Pnak" units="milliS_per_microF"/>
<variable name="R" public_interface="in" units="joule_per_kilomole_kelvin"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="F" public_interface="in" units="coulomb_per_mole"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="nasl" public_interface="in" units="millimolar"/>
<variable name="ksl" public_interface="in" units="millimolar"/>
<variable name="nao" public_interface="in" units="millimolar"/>
<variable name="ko" public_interface="in" units="millimolar"/>
<variable name="Knai" units="millimolar"/>
<variable name="Knao" units="millimolar"/>
<variable name="P" units="dimensionless"/>
<variable name="a1" units="dimensionless"/>
<variable name="b1" units="dimensionless"/>
<variable name="a2" units="dimensionless"/>
<variable name="b2" units="dimensionless"/>
<variable name="a3" units="dimensionless"/>
<variable name="b3" units="dimensionless"/>
<variable name="a4" units="dimensionless"/>
<variable name="b4" units="dimensionless"/>
<variable name="x1" units="dimensionless"/>
<variable name="x2" units="dimensionless"/>
<variable name="x3" units="dimensionless"/>
<variable name="x4" units="dimensionless"/>
<variable name="E1" units="dimensionless"/>
<variable name="E2" units="dimensionless"/>
<variable name="E3" units="dimensionless"/>
<variable name="E4" units="dimensionless"/>
<variable name="JnakNa" units="millimolar_per_millisecond"/>
<variable name="JnakK" units="millimolar_per_millisecond"/>
<variable name="INaK" public_interface="out" units="microA_per_microF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Knai</ci>
<apply>
<times/>
<ci>Knai0</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>v</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Knao</ci>
<apply>
<times/>
<ci>Knao0</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>delta</ci>
</apply>
<ci>v</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>P</ci>
<apply>
<divide/>
<ci>eP</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>H</ci>
<ci>Khp</ci>
</apply>
<apply>
<divide/>
<ci>nasl</ci>
<ci>Knap</ci>
</apply>
<apply>
<divide/>
<ci>ksl</ci>
<ci>Kxkur</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>a1</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k1p</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>nasl</ci>
<ci>Knai</ci>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nasl</ci>
<ci>Knai</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>ksl</ci>
<ci>Kki</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>b1</ci>
<apply>
<times/>
<ci>k1m</ci>
<ci>MgADP</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>a2</ci>
<ci>k2p</ci>
</apply>
<apply>
<eq/>
<ci>b2</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k2m</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>nao</ci>
<ci>Knao</ci>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nao</ci>
<ci>Knao</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>ko</ci>
<ci>Kko</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>a3</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k3p</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>ko</ci>
<ci>Kko</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nao</ci>
<ci>Knao</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>ko</ci>
<ci>Kko</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>b3</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k3m</ci>
<ci>P</ci>
<ci>H</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>MgATP</ci>
<ci>Kmgatp</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>a4</ci>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<ci>k4p</ci>
<ci>MgATP</ci>
</apply>
<ci>Kmgatp</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>MgATP</ci>
<ci>Kmgatp</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>b4</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k4m</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>ksl</ci>
<ci>Kki</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nasl</ci>
<ci>Knai</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>ksl</ci>
<ci>Kki</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x1</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>a4</ci>
<ci>a1</ci>
<ci>a2</ci>
</apply>
<apply>
<times/>
<ci>b2</ci>
<ci>b4</ci>
<ci>b3</ci>
</apply>
<apply>
<times/>
<ci>a2</ci>
<ci>b4</ci>
<ci>b3</ci>
</apply>
<apply>
<times/>
<ci>b3</ci>
<ci>a1</ci>
<ci>a2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x2</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>b2</ci>
<ci>b1</ci>
<ci>b4</ci>
</apply>
<apply>
<times/>
<ci>a1</ci>
<ci>a2</ci>
<ci>a3</ci>
</apply>
<apply>
<times/>
<ci>a3</ci>
<ci>b1</ci>
<ci>b4</ci>
</apply>
<apply>
<times/>
<ci>a2</ci>
<ci>a3</ci>
<ci>b4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x3</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>a2</ci>
<ci>a3</ci>
<ci>a4</ci>
</apply>
<apply>
<times/>
<ci>b3</ci>
<ci>b2</ci>
<ci>b1</ci>
</apply>
<apply>
<times/>
<ci>b2</ci>
<ci>b1</ci>
<ci>a4</ci>
</apply>
<apply>
<times/>
<ci>a3</ci>
<ci>a4</ci>
<ci>b1</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x4</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>b4</ci>
<ci>b3</ci>
<ci>b2</ci>
</apply>
<apply>
<times/>
<ci>a3</ci>
<ci>a4</ci>
<ci>a1</ci>
</apply>
<apply>
<times/>
<ci>b2</ci>
<ci>a4</ci>
<ci>a1</ci>
</apply>
<apply>
<times/>
<ci>b3</ci>
<ci>b2</ci>
<ci>a1</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E1</ci>
<apply>
<divide/>
<ci>x1</ci>
<apply>
<plus/>
<ci>x1</ci>
<ci>x2</ci>
<ci>x3</ci>
<ci>x4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E2</ci>
<apply>
<divide/>
<ci>x2</ci>
<apply>
<plus/>
<ci>x1</ci>
<ci>x2</ci>
<ci>x3</ci>
<ci>x4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E3</ci>
<apply>
<divide/>
<ci>x3</ci>
<apply>
<plus/>
<ci>x1</ci>
<ci>x2</ci>
<ci>x3</ci>
<ci>x4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E4</ci>
<apply>
<divide/>
<ci>x4</ci>
<apply>
<plus/>
<ci>x1</ci>
<ci>x2</ci>
<ci>x3</ci>
<ci>x4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JnakNa</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<apply>
<minus/>
<apply>
<times/>
<ci>E1</ci>
<ci>a3</ci>
</apply>
<apply>
<times/>
<ci>E2</ci>
<ci>b3</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JnakK</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<apply>
<minus/>
<apply>
<times/>
<ci>E4</ci>
<ci>b1</ci>
</apply>
<apply>
<times/>
<ci>E3</ci>
<ci>a1</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INaK</ci>
<apply>
<times/>
<ci>Pnak</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>zna</ci>
<ci>JnakNa</ci>
</apply>
<apply>
<times/>
<ci>zk</ci>
<ci>JnakK</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="INab">
<variable initial_value="9.375e-10" name="PNab" units="milliS_per_microF"/>
<variable name="INab" public_interface="out" units="microA_per_microF"/>
<variable name="nasl" public_interface="in" units="millimolar"/>
<variable name="nao" public_interface="in" units="millimolar"/>
<variable name="vffrt" public_interface="in" units="coulomb_per_mole"/>
<variable name="vfrt" public_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INab</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>PNab</ci>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>nasl</ci>
<apply>
<exp/>
<ci>vfrt</ci>
</apply>
</apply>
<ci>nao</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<ci>vfrt</ci>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ICab">
<variable initial_value="2.5e-8" name="PCab" units="milliS_per_microF"/>
<variable name="ICab" public_interface="out" units="microA_per_microF"/>
<variable name="casl" public_interface="in" units="millimolar"/>
<variable name="cao" public_interface="in" units="millimolar"/>
<variable name="vffrt" public_interface="in" units="coulomb_per_mole"/>
<variable name="vfrt" public_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICab</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>PCab</ci>
<cn cellml:units="dimensionless">4</cn>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>casl</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vfrt</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.341</cn>
<ci>cao</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vfrt</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IpCa">
<variable initial_value="0.0005" name="GpCa" units="milliS_per_microF"/>
<variable initial_value="0.0005" name="KmCap" units="millimolar"/>
<variable name="IpCa" public_interface="out" units="microA_per_microF"/>
<variable name="casl" public_interface="in" units="millimolar"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IpCa</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>GpCa</ci>
<ci>casl</ci>
</apply>
<apply>
<plus/>
<ci>KmCap</ci>
<ci>casl</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="diff">
<variable initial_value="0.2" name="sstau" units="millisecond"/>
<variable initial_value="12" name="gaptau" units="millisecond"/>
<variable name="cai" public_interface="in" units="millimolar"/>
<variable name="casl" public_interface="in" units="millimolar"/>
<variable name="cass" public_interface="in" units="millimolar"/>
<variable name="nai" public_interface="in" units="millimolar"/>
<variable name="nasl" public_interface="in" units="millimolar"/>
<variable name="nass" public_interface="in" units="millimolar"/>
<variable name="ki" public_interface="in" units="millimolar"/>
<variable name="ksl" public_interface="in" units="millimolar"/>
<variable name="kss" public_interface="in" units="millimolar"/>
<variable name="JdiffNa" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="JgapNa" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="Jdiff" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="Jgap" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="JdiffK" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="JgapK" public_interface="out" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>JdiffNa</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>nass</ci>
<ci>nasl</ci>
</apply>
<ci>sstau</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>JgapNa</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>nasl</ci>
<ci>nai</ci>
</apply>
<ci>gaptau</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>JdiffK</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>kss</ci>
<ci>ksl</ci>
</apply>
<ci>sstau</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>JgapK</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>ksl</ci>
<ci>ki</ci>
</apply>
<ci>gaptau</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Jdiff</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>cass</ci>
<ci>casl</ci>
</apply>
<ci>sstau</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Jgap</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>casl</ci>
<ci>cai</ci>
</apply>
<ci>gaptau</ci>
</apply>
</apply>
</math>
</component>
<component name="ryr">
<variable name="REL" units="millimolar_per_millisecond"/>
<variable name="irelss" units="millimolar_per_millisecond"/>
<variable name="ireltau" units="dimensionless"/>
<variable name="REL2" units="millimolar_per_millisecond"/>
<variable name="irelss2" units="millimolar_per_millisecond"/>
<variable name="ireltau2" units="dimensionless"/>
<variable name="F" public_interface="in" units="coulomb_per_mole"/>
<variable name="Acap" public_interface="in" units="centimeter_squared"/>
<variable name="vss" public_interface="in" units="microliter"/>
<variable name="vsl" public_interface="in" units="microliter"/>
<variable name="vcsr" public_interface="in" units="microliter"/>
<variable name="vnsr" public_interface="in" units="microliter"/>
<variable name="vjsr" public_interface="in" units="microliter"/>
<variable name="vmyo" public_interface="in" units="microliter"/>
<variable name="ICaL" public_interface="in" units="microA_per_microF"/>
<variable name="cajsr" public_interface="in" units="millimolar"/>
<variable name="cacsr" public_interface="in" units="millimolar"/>
<variable name="Jdiff" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jgap" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jip3" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jup2" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="CaMKa" public_interface="in" units="millimolar"/>
<variable initial_value="0.000108240945806962" name="Jrel1" public_interface="out" units="millimolar_per_millisecond"/>
<variable initial_value="1.25045800437317e-69" name="Jrel2" public_interface="out" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>REL</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>ICaL</ci>
<ci>Acap</ci>
</apply>
<apply>
<times/>
<ci>vss</ci>
<ci>F</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<plus/>
<ci>Jrel1</ci>
<ci>Jip3</ci>
</apply>
</apply>
<ci>vjsr</ci>
</apply>
<ci>vss</ci>
</apply>
<ci>Jdiff</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ireltau</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">1</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.28</cn>
<ci>CaMKa</ci>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="millimolar">0.0123</cn>
<ci>cajsr</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>irelss</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">15</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">1</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.28</cn>
<ci>CaMKa</ci>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
</apply>
<ci>REL</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>cajsr</ci>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
<apply>
<gt/>
<ci>REL</ci>
<cn cellml:units="millimolar_per_millisecond">0</cn>
</apply>
</piece>
<otherwise>
<cn cellml:units="millimolar_per_millisecond">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Jrel1</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>irelss</ci>
<ci>Jrel1</ci>
</apply>
<ci>ireltau</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>REL2</ci>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>Jgap</ci>
<ci>vsl</ci>
</apply>
<ci>vmyo</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>Jup2</ci>
</apply>
<ci>vnsr</ci>
</apply>
<ci>vmyo</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>Jrel2</ci>
<ci>vcsr</ci>
</apply>
<ci>vmyo</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ireltau2</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">6</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">1</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.28</cn>
<ci>CaMKa</ci>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.0123</cn>
<ci>cacsr</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>irelss2</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">91</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">1</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.28</cn>
<ci>CaMKa</ci>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
</apply>
<ci>REL2</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>cacsr</ci>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
<apply>
<gt/>
<ci>REL2</ci>
<cn cellml:units="millimolar_per_millisecond">0</cn>
</apply>
</piece>
<otherwise>
<cn cellml:units="millimolar_per_millisecond">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Jrel2</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>irelss2</ci>
<ci>Jrel2</ci>
</apply>
<ci>ireltau2</ci>
</apply>
</apply>
</math>
</component>
<component name="SERCA">
<variable initial_value="0.75" name="dqupcamkbar" units="dimensionless"/>
<variable initial_value="0.00017" name="dkmplbbar" units="dimensionless"/>
<variable initial_value="0.00028" name="kmup" units="dimensionless"/>
<variable initial_value="15" name="nsrbar" units="dimensionless"/>
<variable name="KmCaMK" public_interface="in" units="millimolar"/>
<variable name="CaMKa" public_interface="in" units="millimolar"/>
<variable name="cai" public_interface="in" units="millimolar"/>
<variable name="casl" public_interface="in" units="millimolar"/>
<variable name="cansr" public_interface="in" units="millimolar"/>
<variable name="dkmplb" units="dimensionless"/>
<variable name="dqupcamk" units="dimensionless"/>
<variable name="Jup1" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="Jup2" public_interface="out" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>dkmplb</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>dkmplbbar</ci>
<ci>CaMKa</ci>
</apply>
<apply>
<plus/>
<ci>CaMKa</ci>
<ci>KmCaMK</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>dqupcamk</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>dqupcamkbar</ci>
<ci>CaMKa</ci>
</apply>
<apply>
<plus/>
<ci>CaMKa</ci>
<ci>KmCaMK</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Jup1</ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="millimolar_per_millisecond">0.0002</cn>
<apply>
<plus/>
<ci>dqupcamk</ci>
<cn cellml:units="millimolar_per_millisecond">1</cn>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="millimolar_per_millisecond">1</cn>
<apply>
<divide/>
<apply>
<minus/>
<ci>kmup</ci>
<ci>dkmplb</ci>
</apply>
<ci>casl</ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="millimolar_per_millisecond">0.00105</cn>
<ci>cansr</ci>
</apply>
<ci>nsrbar</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Jup2</ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="millimolar_per_millisecond">0.0026</cn>
<apply>
<plus/>
<ci>dqupcamk</ci>
<cn cellml:units="millimolar_per_millisecond">1</cn>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="millimolar_per_millisecond">1</cn>
<apply>
<divide/>
<apply>
<minus/>
<ci>kmup</ci>
<ci>dkmplb</ci>
</apply>
<ci>cai</ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="millimolar_per_millisecond">0.0042</cn>
<ci>cansr</ci>
</apply>
<ci>nsrbar</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IP3">
<variable initial_value="0.0001" name="IP3" units="dimensionless"/>
<variable initial_value="150000" name="k1" units="dimensionless"/>
<variable initial_value="16.5" name="k1a" units="dimensionless"/>
<variable initial_value="96000" name="k0" units="dimensionless"/>
<variable initial_value="9.6" name="k0a" units="dimensionless"/>
<variable initial_value="1800" name="k2" units="dimensionless"/>
<variable initial_value="0.21" name="k2a" units="dimensionless"/>
<variable initial_value="3.7" name="tauip3" units="millisecond"/>
<variable name="cass" public_interface="in" units="millimolar"/>
<variable name="cajsr" public_interface="in" units="millimolar"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="POip3" units="dimensionless"/>
<variable initial_value="0.466236137183558" name="u" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="Jip3" public_interface="out" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>u</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>cass</ci>
<ci>k2</ci>
<apply>
<minus/>
<cn cellml:units="millimolar_per_millisecond">1</cn>
<ci>u</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k2a</ci>
<ci>u</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>POip3</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>tauip3</ci>
<ci>IP3</ci>
<ci>cass</ci>
<apply>
<minus/>
<cn cellml:units="millimolar_per_millisecond">1</cn>
<ci>u</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="millimolar_per_millisecond">1</cn>
<apply>
<divide/>
<apply>
<times/>
<ci>IP3</ci>
<ci>k0</ci>
</apply>
<ci>k0a</ci>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="millimolar_per_millisecond">1</cn>
<apply>
<divide/>
<apply>
<times/>
<ci>cass</ci>
<ci>k1</ci>
</apply>
<ci>k1a</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Jip3</ci>
<apply>
<times/>
<cn cellml:units="millimolar_per_millisecond">10.92</cn>
<ci>POip3</ci>
<apply>
<minus/>
<ci>cajsr</ci>
<ci>cass</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="trans_flux">
<variable name="cansr" public_interface="in" units="millimolar"/>
<variable name="cajsr" public_interface="in" units="millimolar"/>
<variable name="cacsr" public_interface="in" units="millimolar"/>
<variable name="Jtr1" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="Jtr2" public_interface="out" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Jtr1</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>cansr</ci>
<ci>cajsr</ci>
</apply>
<cn cellml:units="millisecond">120</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Jtr2</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>cansr</ci>
<ci>cacsr</ci>
</apply>
<cn cellml:units="millisecond">120</cn>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="intracellular_ions" component_2="INaL"/>
<map_variables variable_1="INaL" variable_2="INaL"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="membrane"/>
<map_variables variable_1="Istim" variable_2="Istim"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="trans_flux"/>
<map_variables variable_1="cajsr" variable_2="cajsr"/>
<map_variables variable_1="cansr" variable_2="cansr"/>
<map_variables variable_1="cacsr" variable_2="cacsr"/>
<map_variables variable_1="Jtr1" variable_2="Jtr1"/>
<map_variables variable_1="Jtr2" variable_2="Jtr2"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="SERCA"/>
<map_variables variable_1="cai" variable_2="cai"/>
<map_variables variable_1="casl" variable_2="casl"/>
<map_variables variable_1="cansr" variable_2="cansr"/>
<map_variables variable_1="Jup1" variable_2="Jup1"/>
<map_variables variable_1="Jup2" variable_2="Jup2"/>
</connection>
<connection>
<map_components component_1="SERCA" component_2="CaMK"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="ryr"/>
<map_variables variable_1="cajsr" variable_2="cajsr"/>
<map_variables variable_1="cacsr" variable_2="cacsr"/>
<map_variables variable_1="Jrel1" variable_2="Jrel1"/>
<map_variables variable_1="Jrel2" variable_2="Jrel2"/>
</connection>
<connection>
<map_components component_1="cell_geometry" component_2="ryr"/>
<map_variables variable_1="Acap" variable_2="Acap"/>
<map_variables variable_1="vcsr" variable_2="vcsr"/>
<map_variables variable_1="vjsr" variable_2="vjsr"/>
<map_variables variable_1="vnsr" variable_2="vnsr"/>
<map_variables variable_1="vsl" variable_2="vsl"/>
<map_variables variable_1="vss" variable_2="vss"/>
<map_variables variable_1="vmyo" variable_2="vmyo"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IP3"/>
<map_variables variable_1="cajsr" variable_2="cajsr"/>
<map_variables variable_1="cass" variable_2="cass"/>
<map_variables variable_1="Jip3" variable_2="Jip3"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="ryr"/>
<map_variables variable_1="ICaL" variable_2="ICaL"/>
</connection>
<connection>
<map_components component_1="SERCA" component_2="ryr"/>
<map_variables variable_1="Jup2" variable_2="Jup2"/>
</connection>
<connection>
<map_components component_1="physical_constants" component_2="ryr"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="diff" component_2="ryr"/>
<map_variables variable_1="Jdiff" variable_2="Jdiff"/>
<map_variables variable_1="Jgap" variable_2="Jgap"/>
</connection>
<connection>
<map_components component_1="ryr" component_2="CaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="ryr" component_2="IP3"/>
<map_variables variable_1="Jip3" variable_2="Jip3"/>
</connection>
<connection>
<map_components component_1="ryr" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="IP3" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="diff"/>
<map_variables variable_1="cai" variable_2="cai"/>
<map_variables variable_1="casl" variable_2="casl"/>
<map_variables variable_1="cass" variable_2="cass"/>
<map_variables variable_1="nai" variable_2="nai"/>
<map_variables variable_1="nasl" variable_2="nasl"/>
<map_variables variable_1="nass" variable_2="nass"/>
<map_variables variable_1="ki" variable_2="ki"/>
<map_variables variable_1="ksl" variable_2="ksl"/>
<map_variables variable_1="kss" variable_2="kss"/>
<map_variables variable_1="JdiffK" variable_2="JdiffK"/>
<map_variables variable_1="JgapK" variable_2="JgapK"/>
<map_variables variable_1="Jdiff" variable_2="Jdiff"/>
<map_variables variable_1="Jgap" variable_2="Jgap"/>
<map_variables variable_1="JdiffNa" variable_2="JdiffNa"/>
<map_variables variable_1="JgapNa" variable_2="JgapNa"/>
</connection>
<connection>
<map_components component_1="IpCa" component_2="membrane"/>
<map_variables variable_1="IpCa" variable_2="IpCa"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IpCa"/>
<map_variables variable_1="casl" variable_2="casl"/>
<map_variables variable_1="IpCa" variable_2="IpCa"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="ICab"/>
<map_variables variable_1="cao" variable_2="cao"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="ICab"/>
<map_variables variable_1="casl" variable_2="casl"/>
<map_variables variable_1="ICab" variable_2="ICab"/>
</connection>
<connection>
<map_components component_1="ICab" component_2="membrane"/>
<map_variables variable_1="vffrt" variable_2="vffrt"/>
<map_variables variable_1="vfrt" variable_2="vfrt"/>
<map_variables variable_1="ICab" variable_2="ICab"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="INab"/>
<map_variables variable_1="nao" variable_2="nao"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="INab"/>
<map_variables variable_1="nasl" variable_2="nasl"/>
<map_variables variable_1="INab" variable_2="INab"/>
</connection>
<connection>
<map_components component_1="INab" component_2="membrane"/>
<map_variables variable_1="vffrt" variable_2="vffrt"/>
<map_variables variable_1="vfrt" variable_2="vfrt"/>
<map_variables variable_1="INab" variable_2="INab"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="INaK"/>
<map_variables variable_1="ksl" variable_2="ksl"/>
<map_variables variable_1="nasl" variable_2="nasl"/>
<map_variables variable_1="INaK" variable_2="INaK"/>
</connection>
<connection>
<map_components component_1="INaK" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="INaK" variable_2="INaK"/>
</connection>
<connection>
<map_components component_1="INaK" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="zna" variable_2="zna"/>
<map_variables variable_1="zk" variable_2="zk"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="INaK"/>
<map_variables variable_1="nao" variable_2="nao"/>
<map_variables variable_1="ko" variable_2="ko"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="INaCa_i"/>
<map_variables variable_1="casl" variable_2="casl"/>
<map_variables variable_1="nasl" variable_2="nasl"/>
<map_variables variable_1="nass" variable_2="nass"/>
<map_variables variable_1="cass" variable_2="cass"/>
<map_variables variable_1="INaCa_i" variable_2="INaCa_i"/>
<map_variables variable_1="INaCa_ss" variable_2="INaCa_ss"/>
</connection>
<connection>
<map_components component_1="INaCa_i" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="INaCa_i" variable_2="INaCa_i"/>
<map_variables variable_1="INaCa_ss" variable_2="INaCa_ss"/>
</connection>
<connection>
<map_components component_1="INaCa_i" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="zna" variable_2="zna"/>
<map_variables variable_1="zca" variable_2="zca"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="INaCa_i"/>
<map_variables variable_1="nao" variable_2="nao"/>
<map_variables variable_1="cao" variable_2="cao"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IKs"/>
<map_variables variable_1="casl" variable_2="casl"/>
<map_variables variable_1="IKs" variable_2="IKs"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="ICaT"/>
<map_variables variable_1="ICaT" variable_2="ICaT"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="Isus"/>
<map_variables variable_1="Isus" variable_2="Isus"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="If"/>
<map_variables variable_1="IfNa" variable_2="IfNa"/>
<map_variables variable_1="IfK" variable_2="IfK"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="IK1" variable_2="IK1"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="IKs" variable_2="IKs"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="ICaT" variable_2="ICaT"/>
</connection>
<connection>
<map_components component_1="Isus" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="Isus" variable_2="Isus"/>
</connection>
<connection>
<map_components component_1="If" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="If" variable_2="If"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="If" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="reversal_potentials"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="reversal_potentials"/>
<map_variables variable_1="EKs" variable_2="EKs"/>
</connection>
<connection>
<map_components component_1="ICaT" component_2="reversal_potentials"/>
<map_variables variable_1="ECa" variable_2="ECa"/>
</connection>
<connection>
<map_components component_1="Isus" component_2="reversal_potentials"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="If" component_2="reversal_potentials"/>
<map_variables variable_1="ENa" variable_2="ENa"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="Ito" variable_2="Ito"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="INaL" variable_2="INaL"/>
</connection>
<connection>
<map_components component_1="IKr" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="IKr" variable_2="IKr"/>
</connection>
<connection>
<map_components component_1="IKr" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="reversal_potentials"/>
<map_variables variable_1="ENa" variable_2="ENa"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="reversal_potentials"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="CaMK"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="INa"/>
<map_variables variable_1="tm" variable_2="tm"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="CaMK"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="CaMK" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="ICaL"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="vffrt" variable_2="vffrt"/>
<map_variables variable_1="vfrt" variable_2="vfrt"/>
<map_variables variable_1="ICaL" variable_2="ICaL"/>
<map_variables variable_1="ICaNa" variable_2="ICaNa"/>
<map_variables variable_1="ICaK" variable_2="ICaK"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="ICaL"/>
<map_variables variable_1="cass" variable_2="cass"/>
<map_variables variable_1="nass" variable_2="nass"/>
<map_variables variable_1="kss" variable_2="kss"/>
<map_variables variable_1="ICaNa" variable_2="ICaNa"/>
<map_variables variable_1="ICaK" variable_2="ICaK"/>
<map_variables variable_1="ICaL" variable_2="ICaL"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="IK1"/>
<map_variables variable_1="ko" variable_2="ko"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IK1"/>
<map_variables variable_1="IK1" variable_2="IK1"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="ICaL"/>
<map_variables variable_1="nao" variable_2="nao"/>
<map_variables variable_1="ko" variable_2="ko"/>
<map_variables variable_1="cao" variable_2="cao"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="IKr"/>
<map_variables variable_1="ko" variable_2="ko"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IKr"/>
<map_variables variable_1="IKr" variable_2="IKr"/>
</connection>
<connection>
<map_components component_1="reversal_potentials" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="reversal_potentials" component_2="IKr"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="reversal_potentials" component_2="INa"/>
<map_variables variable_1="ENa" variable_2="ENa"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="INa"/>
<map_variables variable_1="INa" variable_2="INa"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="Ito"/>
<map_variables variable_1="Ito" variable_2="Ito"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="INa"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="INa" variable_2="INa"/>
</connection>
<connection>
<map_components component_1="CaMK" component_2="INa"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="INa" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="CaMK"/>
<map_variables variable_1="cass" variable_2="cass"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="cell_geometry"/>
<map_variables variable_1="Acap" variable_2="Acap"/>
<map_variables variable_1="vmyo" variable_2="vmyo"/>
<map_variables variable_1="vss" variable_2="vss"/>
<map_variables variable_1="vsl" variable_2="vsl"/>
<map_variables variable_1="vnsr" variable_2="vnsr"/>
<map_variables variable_1="vjsr" variable_2="vjsr"/>
<map_variables variable_1="vcsr" variable_2="vcsr"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="reversal_potentials"/>
<map_variables variable_1="nasl" variable_2="nasl"/>
<map_variables variable_1="ksl" variable_2="ksl"/>
<map_variables variable_1="casl" variable_2="casl"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="reversal_potentials"/>
<map_variables variable_1="nao" variable_2="nao"/>
<map_variables variable_1="ko" variable_2="ko"/>
<map_variables variable_1="cao" variable_2="cao"/>
</connection>
</model>