Modeling the mammalian circadian clock: sensitivity analysis and multiplicity of oscillatory mechanisms
Mona
Zhu
Auckland Bioengineering Institute, The University of Auckland
Model Status
This is an import for the model "leloup_2004_1.1model.cellml". It is used to define a reoccuring structure within the model and may be used for multiple equations in the model. This file is known to run only in OpenCell in conjunction with the base file.
Model Structure
Modeling the mammalian circadian clock: sensitivity analysis and multiplicity of oscillatory mechanisms, Jean-Christophe Leloup and Albert Goldbeter, 2004,
Journal of Theoretical Biology, 230, 541-562. PubMed ID: 15363675
$\frac{d M}{d \mathrm{time}}=\mathrm{vs}\frac{A^{c}}{B^{c}+A^{c}}-\mathrm{vm}\frac{M}{\mathrm{Km}+M}+\mathrm{kdm}M$
Zhu
Xin Yue
Mona
xzhu055@aucklanduni.ac.nz
The University of Auckland
Auckland Bioengineering Institute
29-12-2010
Modeling the mammalian circadian clock: sensitivity analysis and multiplicity of oscillatory mechanisms
This is a CellML description of Leloup and Goldbeter's 2004 mathematical model of the mammalian circadian clock.
Mona Zhu
15363675
Leloup
Jean-Christophe
Goldbeter
Albert
Modeling the mammalian circadian clock: sensitivity analysis and multiplicity of oscillatory mechanisms
Journal of Theoretical Biology
230
541
562