- Author:
- Hanne Nielsen <hnie010@aucklanduni.ac.nz>
- Date:
- 2011-09-02 10:44:46+12:00
- Desc:
- Added details to the HTML file
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/chauhan_legewie_westermark_lorenzen_herzel_2008/rawfile/93568094db734beaae3fb4a43f0ca1e523dcbaf3/chauhan_2008.cellml
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This CellML file was generated on 8/22/2011 at 11:57:44 at AM using:
COR (0.9.31.1409)
Copyright 2002-2011 Dr Alan Garny
http://cor.physiol.ox.ac.uk/ - cor@physiol.ox.ac.uk
CellML 1.0 was used to generate this model
http://www.cellml.org/
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<variable cmeta:id="HBEGF_HBEGF" initial_value="0" name="HBEGF" public_interface="out" units="mole_per_litre"/>
<variable name="v6" public_interface="in" units="mole_per_litre_per_hour"/>
<variable name="D" public_interface="in" units="mole_per_litre"/>
<variable name="k61" public_interface="in" units="mole_per_litre"/>
<variable name="k62" public_interface="in" units="mole_per_litre"/>
<variable name="k63" public_interface="in" units="mole_per_litre"/>
<variable name="IEG" public_interface="in" units="mole_per_litre"/>
<variable name="HGF" public_interface="in" units="mole_per_litre"/>
<variable name="d6" public_interface="in" units="per_hour"/>
<variable name="time" public_interface="in" units="hour"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>HBEGF</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>v6</ci>
<apply>
<divide/>
<apply>
<power/>
<ci>D</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">4</cn>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci>k61</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">4</cn>
</apply>
<apply>
<power/>
<ci>D</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">4</cn>
</apply>
</apply>
</apply>
<apply>
<divide/>
<ci>IEG</ci>
<apply>
<plus/>
<ci>k62</ci>
<ci>IEG</ci>
</apply>
</apply>
<apply>
<divide/>
<ci>HGF</ci>
<apply>
<plus/>
<ci>k63</ci>
<ci>HGF</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>d6</ci>
<ci>HBEGF</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IEG">
<variable cmeta:id="IEG_IEG" initial_value="0" name="IEG" public_interface="out" units="mole_per_litre"/>
<variable name="v3" public_interface="in" units="mole_per_litre_per_hour"/>
<variable name="PIC" public_interface="in" units="mole_per_litre"/>
<variable name="k3" public_interface="in" units="mole_per_litre"/>
<variable name="d3" public_interface="in" units="per_hour"/>
<variable name="time" public_interface="in" units="hour"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>IEG</ci>
</apply>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>v3</ci>
<apply>
<power/>
<ci>PIC</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci>k3</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<ci>PIC</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>d3</ci>
<ci>IEG</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="PAI">
<variable cmeta:id="PAI_PAI" initial_value="0" name="PAI" public_interface="out" units="mole_per_litre"/>
<variable name="v4" public_interface="in" units="mole_per_litre_per_hour"/>
<variable name="PIC" public_interface="in" units="mole_per_litre"/>
<variable name="k4" public_interface="in" units="mole_per_litre"/>
<variable name="d4" public_interface="in" units="per_hour"/>
<variable name="time" public_interface="in" units="hour"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>PAI</ci>
</apply>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>v4</ci>
<apply>
<power/>
<ci>PIC</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci>k4</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<ci>PIC</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>d4</ci>
<ci>PAI</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="model_parameters">
<variable initial_value="4" name="I0" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.05" name="d0" public_interface="out" units="per_hour"/>
<variable initial_value="2" name="v1" public_interface="out" units="mole_per_litre_per_hour"/>
<variable initial_value="1" name="km1" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.5" name="k1" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.7" name="d1" public_interface="out" units="per_hour"/>
<variable initial_value="0.8" name="v2" public_interface="out" units="per_hour"/>
<variable initial_value="0.01" name="d2" public_interface="out" units="per_hour"/>
<variable initial_value="6" name="v3" public_interface="out" units="mole_per_litre_per_hour"/>
<variable initial_value="0.5" name="k3" public_interface="out" units="mole_per_litre"/>
<variable initial_value="10" name="d3" public_interface="out" units="per_hour"/>
<variable initial_value="60" name="v4" public_interface="out" units="mole_per_litre_per_hour"/>
<variable initial_value="0.5" name="k4" public_interface="out" units="mole_per_litre"/>
<variable initial_value="10" name="d4" public_interface="out" units="per_hour"/>
<variable initial_value="8.1" name="v5" public_interface="out" units="per_mole_per_litre"/>
<variable initial_value="5" name="f5" public_interface="out" units="mole_per_litre_per_hour"/>
<variable initial_value="0.125" name="k5" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.18" name="km5" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.008" name="d5" public_interface="out" units="per_hour"/>
<variable initial_value="24" name="v6" public_interface="out" units="mole_per_litre_per_hour"/>
<variable initial_value="0.9" name="k61" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.0005" name="k62" public_interface="out" units="mole_per_litre"/>
<variable initial_value="1" name="k63" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.1" name="d6" public_interface="out" units="per_hour"/>
<variable initial_value="1.6" name="v7" public_interface="out" units="per_hour"/>
<variable initial_value="0.3" name="d7" public_interface="out" units="per_hour"/>
<variable initial_value="0.8" name="v8" public_interface="out" units="per_hour"/>
<variable initial_value="0.005" name="k8" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.002" name="d8" public_interface="out" units="per_hour"/>
<variable initial_value="0.8" name="v91" public_interface="out" units="per_hour"/>
<variable initial_value="40" name="k91" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.16" name="v92" public_interface="out" units="per_hour"/>
<variable initial_value="10" name="k92" public_interface="out" units="mole_per_litre"/>
<variable initial_value="0.0002" name="d9" public_interface="out" units="per_hour"/>
<variable initial_value="0.8" name="v10" public_interface="out" units="per_mole_per_litre_per_hour"/>
<variable initial_value="8.1" name="d10" public_interface="out" units="per_hour"/>
<variable initial_value="800" name="v11" public_interface="out" units="per_mole_per_litre_per_hour"/>
<variable initial_value="800" name="d11" public_interface="out" units="per_hour"/>
<variable initial_value="0.56" name="v12" public_interface="out" units="mole_per_litre_per_hour"/>
<variable initial_value="0.025" name="d12" public_interface="out" units="per_hour"/>
</component>
<connection>
<map_components component_1="CycE" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="CycD" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="CycECKI" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="CycDCKI" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="PIC" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="CKI" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="HGF" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="PGE" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="D" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="deg" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="HBEGF" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="IEG" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="PAI" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="D" component_2="PIC"/>
<map_variables variable_1="D" variable_2="D"/>
</connection>
<connection>
<map_components component_1="PGE" component_2="PIC"/>
<map_variables variable_1="PIC" variable_2="PIC"/>
<map_variables variable_1="PGE" variable_2="PGE"/>
</connection>
<connection>
<map_components component_1="IEG" component_2="PIC"/>
<map_variables variable_1="PIC" variable_2="PIC"/>
</connection>
<connection>
<map_components component_1="PAI" component_2="PIC"/>
<map_variables variable_1="PIC" variable_2="PIC"/>
</connection>
<connection>
<map_components component_1="IEG" component_2="HGF"/>
<map_variables variable_1="IEG" variable_2="IEG"/>
</connection>
<connection>
<map_components component_1="IEG" component_2="HBEGF"/>
<map_variables variable_1="IEG" variable_2="IEG"/>
</connection>
<connection>
<map_components component_1="IEG" component_2="CycD"/>
<map_variables variable_1="IEG" variable_2="IEG"/>
</connection>
<connection>
<map_components component_1="PAI" component_2="HGF"/>
<map_variables variable_1="PAI" variable_2="PAI"/>
</connection>
<connection>
<map_components component_1="HBEGF" component_2="CycE"/>
<map_variables variable_1="HBEGF" variable_2="HBEGF"/>
</connection>
<connection>
<map_components component_1="HBEGF" component_2="CycD"/>
<map_variables variable_1="HBEGF" variable_2="HBEGF"/>
</connection>
<connection>
<map_components component_1="HBEGF" component_2="D"/>
<map_variables variable_1="D" variable_2="D"/>
</connection>
<connection>
<map_components component_1="HBEGF" component_2="HGF"/>
<map_variables variable_1="HGF" variable_2="HGF"/>
</connection>
<connection>
<map_components component_1="CKI" component_2="CycD"/>
<map_variables variable_1="CKI" variable_2="CKI"/>
<map_variables variable_1="CycD" variable_2="CycD"/>
</connection>
<connection>
<map_components component_1="CKI" component_2="CycE"/>
<map_variables variable_1="CKI" variable_2="CKI"/>
<map_variables variable_1="CycE" variable_2="CycE"/>
</connection>
<connection>
<map_components component_1="CKI" component_2="CycECKI"/>
<map_variables variable_1="CKI" variable_2="CKI"/>
<map_variables variable_1="CycECKI" variable_2="CycECKI"/>
</connection>
<connection>
<map_components component_1="CKI" component_2="CycDCKI"/>
<map_variables variable_1="CKI" variable_2="CKI"/>
<map_variables variable_1="CycDCKI" variable_2="CycDCKI"/>
</connection>
<connection>
<map_components component_1="CKI" component_2="PIC"/>
<map_variables variable_1="PIC" variable_2="PIC"/>
</connection>
<connection>
<map_components component_1="CycD" component_2="CycE"/>
<map_variables variable_1="CycD" variable_2="CycD"/>
</connection>
<connection>
<map_components component_1="CycD" component_2="CycDCKI"/>
<map_variables variable_1="CycD" variable_2="CycD"/>
<map_variables variable_1="CycDCKI" variable_2="CycDCKI"/>
</connection>
<connection>
<map_components component_1="deg" component_2="CycD"/>
<map_variables variable_1="deg" variable_2="deg"/>
</connection>
<connection>
<map_components component_1="deg" component_2="CycE"/>
<map_variables variable_1="CycE" variable_2="CycE"/>
<map_variables variable_1="deg" variable_2="deg"/>
</connection>
<connection>
<map_components component_1="CycECKI" component_2="CycE"/>
<map_variables variable_1="CycE" variable_2="CycE"/>
<map_variables variable_1="CycECKI" variable_2="CycECKI"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="CycE"/>
<map_variables variable_1="v91" variable_2="v91"/>
<map_variables variable_1="k91" variable_2="k91"/>
<map_variables variable_1="v92" variable_2="v92"/>
<map_variables variable_1="k92" variable_2="k92"/>
<map_variables variable_1="d11" variable_2="d11"/>
<map_variables variable_1="d9" variable_2="d9"/>
<map_variables variable_1="v11" variable_2="v11"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="CycD"/>
<map_variables variable_1="v8" variable_2="v8"/>
<map_variables variable_1="k8" variable_2="k8"/>
<map_variables variable_1="d10" variable_2="d10"/>
<map_variables variable_1="d8" variable_2="d8"/>
<map_variables variable_1="v10" variable_2="v10"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="CycECKI"/>
<map_variables variable_1="v11" variable_2="v11"/>
<map_variables variable_1="d11" variable_2="d11"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="CycDCKI"/>
<map_variables variable_1="v10" variable_2="v10"/>
<map_variables variable_1="d10" variable_2="d10"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="CKI"/>
<map_variables variable_1="v7" variable_2="v7"/>
<map_variables variable_1="d7" variable_2="d7"/>
<map_variables variable_1="d10" variable_2="d10"/>
<map_variables variable_1="d11" variable_2="d11"/>
<map_variables variable_1="v10" variable_2="v10"/>
<map_variables variable_1="v11" variable_2="v11"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="HGF"/>
<map_variables variable_1="v5" variable_2="v5"/>
<map_variables variable_1="d5" variable_2="d5"/>
<map_variables variable_1="k5" variable_2="k5"/>
<map_variables variable_1="f5" variable_2="f5"/>
<map_variables variable_1="km5" variable_2="km5"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="PGE"/>
<map_variables variable_1="v2" variable_2="v2"/>
<map_variables variable_1="d2" variable_2="d2"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="PIC"/>
<map_variables variable_1="v1" variable_2="v1"/>
<map_variables variable_1="d1" variable_2="d1"/>
<map_variables variable_1="k1" variable_2="k1"/>
<map_variables variable_1="km1" variable_2="km1"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="D"/>
<map_variables variable_1="I0" variable_2="I0"/>
<map_variables variable_1="d0" variable_2="d0"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="deg"/>
<map_variables variable_1="v12" variable_2="v12"/>
<map_variables variable_1="d12" variable_2="d12"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="HBEGF"/>
<map_variables variable_1="v6" variable_2="v6"/>
<map_variables variable_1="d6" variable_2="d6"/>
<map_variables variable_1="k63" variable_2="k63"/>
<map_variables variable_1="k62" variable_2="k62"/>
<map_variables variable_1="k61" variable_2="k61"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="IEG"/>
<map_variables variable_1="v3" variable_2="v3"/>
<map_variables variable_1="d3" variable_2="d3"/>
<map_variables variable_1="k3" variable_2="k3"/>
</connection>
<connection>
<map_components component_1="model_parameters" component_2="PAI"/>
<map_variables variable_1="v4" variable_2="v4"/>
<map_variables variable_1="k4" variable_2="k4"/>
<map_variables variable_1="d4" variable_2="d4"/>
</connection>
</model>
