- Author:
- schdemp <sdem348@aucklanduni.ac.nz>
- Date:
- 2022-06-16 18:11:58-04:00
- Desc:
- Change parameter file names and subsequent loading name strings
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/8a2/rawfile/6c4ba7884bad10ef792565cfc3d30eb9fec6748c/sten2020_neuron_GABAergicNPY.cellml
<?xml version='1.0'?>
<model name="gabaNPY_neuron" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<!--import units-->
<import xlink:href="sten2020_units.cellml">
<units name="Hz" units_ref="Hz"/>
</import>
<!-- define GABAergic NPY pathway-->
<component name="gabaNPY">
<!--import coefficients-->
<variable name="t" public_interface="in" units="second"/>
<variable name="N_NPY" public_interface="in" units="dimensionless"/>
<variable name="k_Ca" public_interface="in" units="per_sec"/>
<variable name="sink_Ca_NPY" public_interface="in" units="per_sec"/>
<variable name="k_NPY" public_interface="in" units="per_sec"/>
<variable name="V_max" public_interface="in" units="per_sec"/>
<variable name="K_M" public_interface="in" units="dimensionless"/>
<variable name="sink_NPY" public_interface="in" units="per_sec"/>
<variable name="initCA_NPY" public_interface="in" units="dimensionless"/>
<variable name="initNPY" public_interface="in" units="dimensionless"/>
<variable name="initNPY_vsm" public_interface="in" units="dimensionless"/>
<!--set steady state initial value-->
<variable initial_value="initCA_NPY" name="Ca_NPY" public_interface="out" units="dimensionless"/>
<variable initial_value="initNPY" name="NPY" public_interface="out" units="dimensionless"/>
<variable initial_value="initNPY_vsm" name="NPY_vsm" public_interface="out" units="dimensionless"/>
<!--set ode's-->
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>Ca_NPY</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>k_Ca</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<ci>N_NPY</ci>
</apply>
</apply>
<apply>
<times/>
<ci>sink_Ca_NPY</ci>
<ci>Ca_NPY</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>NPY</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>k_NPY</ci>
<ci>Ca_NPY</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>V_max</ci>
<ci>NPY</ci>
</apply>
<apply>
<plus/>
<ci>K_M</ci>
<ci>NPY</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>NPY_vsm</ci>
</apply>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>V_max</ci>
<ci>NPY</ci>
</apply>
<apply>
<plus/>
<ci>K_M</ci>
<ci>NPY</ci>
</apply>
</apply>
<apply>
<times/>
<ci>sink_NPY</ci>
<ci>NPY_vsm</ci>
</apply>
</apply>
</apply>
</math>
</component>
</model>
