- Author:
- Soroush Safaei <ssaf006@aucklanduni.ac.nz>
- Date:
- 2018-08-02 05:37:03+12:00
- Desc:
- fixing diffusion
- Permanent Source URI:
- https://models.physiomeproject.org/workspace/436/rawfile/89cd53399e44e02d8db73780f55d1b1c8b85fe85/ENaC.cellml
<?xml version='1.0'?>
<model name="ENaC" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#">
<component name="ENaC">
<variable name="q_Na_c" public_interface="in" units="M"/>
<variable name="q_Na_a" public_interface="in" units="M"/>
<variable name="z_Na" public_interface="in" units="dimensionless"/>
<variable name="R" public_interface="in" units="J_per_mol_K"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="V_a" public_interface="in" units="volt"/>
<variable name="A_Apical" public_interface="in" units="m2"/>
<variable name="F" public_interface="in" units="C_per_mol"/>
<variable name="J_ENaC" public_interface="out" units="umol_per_s"/>
<variable name="J_ENaC1" public_interface="out" units="umol_per_s"/>
<variable name="I_ENaC" public_interface="out" units="uA"/>
<variable name="V_A_Na" public_interface="out" units="volt"/>
<variable initial_value="9" name="G_ENaC" public_interface="out" units="S"/>
<!-- alpha is not multipled by area in order to have a dimensionless unit, so the unit is actually 1/m2, it's necessary to the same for CFTR as well-->
<variable initial_value="0.1" name="alpha_ENaC" public_interface="out" units="per_m2"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J_ENaC</ci>
<apply>
<divide/>
<ci>I_ENaC</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>J_ENaC1</ci>
<apply>
<times/>
<ci>J_ENaC</ci>
<cn cellml:units="dimensionless" type="e-notation">36<sep/>8</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>V_A_Na</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<apply>
<times/>
<ci>z_Na</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>q_Na_a</ci>
<ci>q_Na_c</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>I_ENaC</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless" type="e-notation">1<sep/>+6</cn>
</apply>
<ci>G_ENaC</ci>
<ci>alpha_ENaC</ci>
<ci>A_Apical</ci>
<apply>
<minus/>
<ci>V_a</ci>
<ci>V_A_Na</ci>
</apply>
</apply>
</apply>
</math>
</component>
</model>
