- Author:
- Hanne Nielsen <hnie010@aucklanduni.ac.nz>
- Date:
- 2011-03-11 12:59:29+13:00
- Desc:
- Added CellML file. Runs in OpenCell but does not reproduce results exactly.
- Permanent Source URI:
- https://models.physiomeproject.org/w/hnielsen/schmitmeier_2007/rawfile/343e38b68ea73e8378abfe89a1a101992dce16d1/schmitmeier_2007.cellml
<?xml version="1.0" encoding="utf-8"?>
<!--
This CellML file was generated on 11/03/2011 at 12:46:38 at p.m. using:
COR (0.9.31.1409)
Copyright 2002-2011 Dr Alan Garny
http://cor.physiol.ox.ac.uk/ - cor@physiol.ox.ac.uk
CellML 1.0 was used to generate this model
http://www.cellml.org/
-->
<model name="schmitmeier_2007_guess_units" cmeta:id="schmitmeier_2007_guess_units" xmlns="http://www.cellml.org/cellml/1.0#" xmlns:cellml="http://www.cellml.org/cellml/1.0#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<units xmlns="http://www.cellml.org/cellml/1.0#" name="hour">
<unit units="second" multiplier="36600"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="day">
<unit units="hour" multiplier="24"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="per_day">
<unit units="day" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="microgram">
<unit units="gram" prefix="micro"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="microgram_per_hour">
<unit units="microgram"/>
<unit units="hour" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="molar">
<unit units="mole"/>
<unit units="litre" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="CONCENTRATIONO2">
<unit units="molar"/>
<unit units="hour" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="CONCENTRATIONH2O2">
<unit units="molar"/>
<unit units="hour" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="CONFIRMp1">
<unit units="molar"/>
<unit units="hour" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="CONFIRMki">
<unit units="molar"/>
<unit units="hour" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="CONFIRMV">
<unit units="molar"/>
<unit units="hour" exponent="-1"/>
</units>
<component xmlns="http://www.cellml.org/cellml/1.0#" name="environment">
<variable name="time" units="hour" public_interface="out"/>
</component>
<component xmlns="http://www.cellml.org/cellml/1.0#" name="O2">
<variable name="O2" units="CONCENTRATIONO2" initial_value="0.00235897" public_interface="out"/>
<variable name="p1" units="CONFIRMp1" initial_value="0.0000143385"/>
<variable name="F1" units="dimensionless" initial_value="20"/>
<variable name="p2" units="per_day" public_interface="in"/>
<variable name="time" units="hour" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>O2</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>p1</ci>
<ci>F1</ci>
</apply>
<apply>
<times/>
<ci>p2</ci>
<ci>O2</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component xmlns="http://www.cellml.org/cellml/1.0#" name="H2O2">
<variable name="H2O2" units="CONCENTRATIONH2O2" initial_value="0.000027947" public_interface="out"/>
<variable name="p2" units="per_day" public_interface="in"/>
<variable name="O2" units="CONCENTRATIONO2" public_interface="in"/>
<variable name="p3" units="per_day" initial_value="2.552293418"/>
<variable name="p4" units="per_day" initial_value="8.379310334"/>
<variable name="time" units="hour" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>H2O2</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>p2</ci>
<ci>O2</ci>
</apply>
<apply>
<times/>
<ci>p3</ci>
<ci>H2O2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>p4</ci>
<ci>H2O2</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component xmlns="http://www.cellml.org/cellml/1.0#" name="V">
<variable name="V" units="CONFIRMV" public_interface="out"/>
<variable name="Vmax" units="microgram_per_hour" initial_value="10400000"/>
<variable name="ki" units="CONFIRMki" initial_value="0.000008982"/>
<variable name="H2O2" units="CONCENTRATIONH2O2" public_interface="in"/>
<variable name="time" units="hour" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>V</ci>
<apply>
<times/>
<ci>Vmax</ci>
<apply>
<divide/>
<ci>ki</ci>
<apply>
<plus/>
<ci>ki</ci>
<ci>H2O2</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component xmlns="http://www.cellml.org/cellml/1.0#" name="model_parameters">
<variable name="p2" units="per_day" initial_value="0.117425199" public_interface="out"/>
</component>
<connection xmlns="http://www.cellml.org/cellml/1.0#">
<map_components component_1="environment" component_2="O2"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection xmlns="http://www.cellml.org/cellml/1.0#">
<map_components component_1="environment" component_2="H2O2"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection xmlns="http://www.cellml.org/cellml/1.0#">
<map_components component_1="environment" component_2="V"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection xmlns="http://www.cellml.org/cellml/1.0#">
<map_components component_1="model_parameters" component_2="O2"/>
<map_variables variable_1="p2" variable_2="p2"/>
</connection>
<connection xmlns="http://www.cellml.org/cellml/1.0#">
<map_components component_1="model_parameters" component_2="H2O2"/>
<map_variables variable_1="p2" variable_2="p2"/>
</connection>
<connection xmlns="http://www.cellml.org/cellml/1.0#">
<map_components component_1="O2" component_2="H2O2"/>
<map_variables variable_1="O2" variable_2="O2"/>
</connection>
<connection xmlns="http://www.cellml.org/cellml/1.0#">
<map_components component_1="H2O2" component_2="V"/>
<map_variables variable_1="H2O2" variable_2="H2O2"/>
</connection>
</model>
