- Author:
- David Nickerson <nickerso@users.sourceforge.net>
- Date:
- 2015-05-25 08:28:39+12:00
- Desc:
- also need to update the CellML namespace
- Permanent Source URI:
- https://models.physiomeproject.org/w/andre/testing-Sed-ML-nesting/rawfile/9def2d7f03b8cd9a7b2471dba578106687bf5faf/Ohara_Rudy_2011.cellml
<?xml version="1.0"?>
<!--
This CellML file was generated on 8/25/2011 at 12:24:17 at AM using:
COR (0.9.31.1409)
Copyright 2002-2011 Dr Alan Garny
http://cor.physiol.ox.ac.uk/ - cor@physiol.ox.ac.uk
CellML 1.0 was used to generate this model
http://www.cellml.org/
--><model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xml:base="file:///H:/SAN-ORd/Ohara_Rudy_2011.cellml" cmeta:id="Ohara_Rudy_2011" name="Ohara_Rudy_2011">
<units name="millisecond">
<unit prefix="milli" units="second"/>
</units>
<units name="per_millisecond">
<unit exponent="-1" units="millisecond"/>
</units>
<units name="millivolt">
<unit prefix="milli" units="volt"/>
</units>
<units name="millivolt_per_millimole">
<unit prefix="milli" units="volt"/>
<unit exponent="-1" units="millimolar"/>
</units>
<units name="per_millivolt">
<unit exponent="-1" units="millivolt"/>
</units>
<units name="per_millivolt_millisecond">
<unit exponent="-1" units="millivolt"/>
<unit exponent="-1" units="millisecond"/>
</units>
<units name="millimolar">
<unit prefix="milli" units="mole"/>
<unit exponent="-1" units="litre"/>
</units>
<units name="per_millimolar">
<unit exponent="-1" units="millimolar"/>
</units>
<units name="millimolar_per_millisecond">
<unit units="millimolar"/>
<unit exponent="-1" units="millisecond"/>
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<unit exponent="-1" units="millisecond"/>
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<unit units="millisecond"/>
<unit exponent="-1" units="millimolar"/>
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<units name="picoA">
<unit prefix="pico" units="ampere"/>
</units>
<units name="microA_per_microF">
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<unit exponent="-1" prefix="micro" units="farad"/>
</units>
<units name="milliS_per_microF">
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<units name="per_micrometre_3">
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<units name="joule_per_kilomole_kelvin">
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<unit exponent="-1" units="kelvin"/>
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<units name="coulomb_per_mole">
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<component name="extracellular">
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<component name="physical_constants">
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<variable initial_value="310" name="T" public_interface="out" units="kelvin"/>
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<times/>
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<plus/>
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<times/>
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<cn cellml:units="dimensionless">3.14</cn>
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<ci>Acap</ci>
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<times/>
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<eq/>
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<times/>
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<times/>
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<times/>
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<eq/>
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<times/>
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<variable cmeta:id="id_00066" name="INab" public_interface="in" units="microA_per_microF"/>
<variable cmeta:id="id_00067" name="IKb" public_interface="in" units="microA_per_microF"/>
<variable cmeta:id="id_00068" name="IpCa" public_interface="in" units="microA_per_microF"/>
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<variable name="Istim" public_interface="out" units="microA_per_microF"/>
<variable initial_value="-80" name="amp" units="microA_per_microF"/>
<variable initial_value="0.5" name="duration" units="millisecond"/>
<variable initial_value="50.0" name="stimStart" units="millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
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<ci>Istim</ci>
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<and/>
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<leq/>
<ci>time</ci>
<apply><plus/>
<ci>stimStart</ci>
<ci>duration</ci>
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<eq/>
<ci>vffrt</ci>
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<divide/>
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<times/>
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<ci>F</ci>
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<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>vfrt</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>v</ci>
<ci>F</ci>
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<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
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<minus/>
<apply>
<plus/>
<ci>INa</ci>
<ci>INaL</ci>
<ci>Ito</ci>
<ci>ICaL</ci>
<ci>ICaNa</ci>
<ci>ICaK</ci>
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<ci>IKs</ci>
<ci>IK1</ci>
<ci>INaCa_i</ci>
<ci>INaCa_ss</ci>
<ci>INaK</ci>
<ci>INab</ci>
<ci>IKb</ci>
<ci>IpCa</ci>
<ci>ICab</ci>
<ci>Istim</ci>
</apply>
</apply>
</apply>
</math>
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<variable cmeta:id="id_00038" initial_value="0.05" name="aCaMK" units="per_millimolar_per_millisecond"/>
<variable cmeta:id="id_00039" initial_value="0.00068" name="bCaMK" units="per_millisecond"/>
<variable cmeta:id="id_00040" initial_value="0.05" name="CaMKo" units="dimensionless"/>
<variable cmeta:id="id_00041" initial_value="0.0015" name="KmCaM" units="millimolar"/>
<variable cmeta:id="id_00042" name="CaMKb" public_interface="out" units="millimolar"/>
<variable cmeta:id="id_00043" name="CaMKa" public_interface="out" units="millimolar"/>
<variable cmeta:id="id_00044" initial_value="0" name="CaMKt" units="millimolar"/>
<variable name="cass" public_interface="in" units="millimolar"/>
<variable name="time" public_interface="in" units="millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>CaMKb</ci>
<apply>
<divide/>
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<times/>
<ci>CaMKo</ci>
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<minus/>
<cn cellml:units="millimolar">1</cn>
<ci>CaMKt</ci>
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<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
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<divide/>
<ci>KmCaM</ci>
<ci>cass</ci>
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<apply>
<eq/>
<ci>CaMKa</ci>
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<plus/>
<ci>CaMKb</ci>
<ci>CaMKt</ci>
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<eq/>
<apply>
<diff/>
<bvar>
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<minus/>
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<times/>
<ci>aCaMK</ci>
<ci>CaMKb</ci>
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<plus/>
<ci>CaMKb</ci>
<ci>CaMKt</ci>
</apply>
</apply>
<apply>
<times/>
<ci>bCaMK</ci>
<ci>CaMKt</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="intracellular_ions">
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<variable cmeta:id="id_00071" name="cmdnmax" units="millimolar"/>
<variable cmeta:id="id_00080" initial_value="0.00238" name="kmcmdn" units="millimolar"/>
<variable cmeta:id="id_00072" initial_value="0.07" name="trpnmax" units="millimolar"/>
<variable cmeta:id="id_00073" initial_value="0.0005" name="kmtrpn" units="millimolar"/>
<variable cmeta:id="id_00074" initial_value="0.047" name="BSRmax" units="millimolar"/>
<variable cmeta:id="id_00075" initial_value="0.00087" name="KmBSR" units="millimolar"/>
<variable cmeta:id="id_00076" initial_value="1.124" name="BSLmax" units="millimolar"/>
<variable cmeta:id="id_00077" initial_value="0.0087" name="KmBSL" units="millimolar"/>
<variable cmeta:id="id_00078" initial_value="10" name="csqnmax" units="millimolar"/>
<variable cmeta:id="id_00079" initial_value="0.8" name="kmcsqn" units="millimolar"/>
<variable initial_value="7" name="nai" public_interface="out" units="millimolar"/>
<variable initial_value="7" name="nass" public_interface="out" units="millimolar"/>
<variable initial_value="145" name="ki" public_interface="out" units="millimolar"/>
<variable initial_value="145" name="kss" public_interface="out" units="millimolar"/>
<variable initial_value="1e-4" name="cass" public_interface="out" units="millimolar"/>
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<variable cmeta:id="id_00081" initial_value="1.2" name="cajsr" public_interface="out" units="millimolar"/>
<variable initial_value="1e-4" name="cai" public_interface="out" units="millimolar"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="Acap" public_interface="in" units="centimeter_squared"/>
<variable name="R" public_interface="in" units="joule_per_kilomole_kelvin"/>
<variable name="T" public_interface="in" units="kelvin"/>
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<variable name="Istim" public_interface="in" units="microA_per_microF"/>
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<variable cmeta:id="id_00094" name="ICab" public_interface="in" units="microA_per_microF"/>
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<variable cmeta:id="id_00096" name="ICaL" public_interface="in" units="microA_per_microF"/>
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<variable cmeta:id="id_00098" name="Jdiff" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="Jup" public_interface="in" units="millimolar_per_millisecond"/>
<variable name="JdiffK" public_interface="in" units="millimolar_per_millisecond"/>
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<variable name="time" public_interface="in" units="millisecond"/>
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<variable name="vnsr" public_interface="in" units="microliter"/>
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<variable name="Bcass" units="dimensionless"/>
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<eq/>
<ci>cmdnmax</ci>
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<piece>
<apply>
<times/>
<ci>cmdnmax_b</ci>
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<eq/>
<ci>celltype</ci>
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<ci>cmdnmax_b</ci>
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<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
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<plus/>
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<divide/>
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<times/>
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<minus/>
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<plus/>
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<times/>
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<times/>
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<ci>INab</ci>
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<times/>
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<divide/>
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<times/>
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<ci>vmyo</ci>
</apply>
</apply>
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<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
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<minus/>
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<divide/>
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<times/>
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<minus/>
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<plus/>
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<times/>
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<times/>
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<ci>vss</ci>
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<ci>JdiffNa</ci>
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<eq/>
<apply>
<diff/>
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<plus/>
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<divide/>
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<minus/>
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<minus/>
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<plus/>
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<ci>IKs</ci>
<ci>IK1</ci>
<ci>IKb</ci>
<ci>Istim</ci>
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<times/>
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<ci>Acap</ci>
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<times/>
<ci>F</ci>
<ci>vmyo</ci>
</apply>
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<apply>
<divide/>
<apply>
<times/>
<ci>JdiffK</ci>
<ci>vss</ci>
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<ci>vmyo</ci>
</apply>
</apply>
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<apply>
<eq/>
<apply>
<diff/>
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<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
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<ci>Acap</ci>
</apply>
<apply>
<times/>
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<ci>vss</ci>
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<ci>JdiffK</ci>
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<eq/>
<ci>Bcai</ci>
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<divide/>
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<plus/>
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<apply>
<divide/>
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<times/>
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<power/>
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<plus/>
<ci>kmcmdn</ci>
<ci>cai</ci>
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<cn cellml:units="dimensionless">2</cn>
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<apply>
<divide/>
<apply>
<times/>
<ci>trpnmax</ci>
<ci>kmtrpn</ci>
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<apply>
<power/>
<apply>
<plus/>
<ci>kmtrpn</ci>
<ci>cai</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
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<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>cai</ci>
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<apply>
<times/>
<ci>Bcai</ci>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<plus/>
<ci>IpCa</ci>
<ci>ICab</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>INaCa_i</ci>
</apply>
</apply>
</apply>
<ci>cm</ci>
<ci>Acap</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>F</ci>
<ci>vmyo</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>Jup</ci>
<ci>vnsr</ci>
</apply>
<ci>vmyo</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>Jdiff</ci>
<ci>vss</ci>
</apply>
<ci>vmyo</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Bcass</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<ci>BSRmax</ci>
<ci>KmBSR</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>KmBSR</ci>
<ci>cass</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>BSLmax</ci>
<ci>KmBSL</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>KmBSL</ci>
<ci>cass</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>cass</ci>
</apply>
<apply>
<times/>
<ci>Bcass</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<minus/>
<ci>ICaL</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>INaCa_ss</ci>
</apply>
</apply>
</apply>
<ci>cm</ci>
<ci>Acap</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>F</ci>
<ci>vss</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>Jrel</ci>
<ci>vjsr</ci>
</apply>
<ci>vss</ci>
</apply>
</apply>
<ci>Jdiff</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>cansr</ci>
</apply>
<apply>
<minus/>
<ci>Jup</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Jtr</ci>
<ci>vjsr</ci>
</apply>
<ci>vnsr</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Bcajsr</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<ci>csqnmax</ci>
<ci>kmcsqn</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>kmcsqn</ci>
<ci>cajsr</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>cajsr</ci>
</apply>
<apply>
<times/>
<ci>Bcajsr</ci>
<apply>
<minus/>
<ci>Jtr</ci>
<ci>Jrel</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00052" name="reversal_potentials">
<variable initial_value="0.01833" name="PKNa" units="dimensionless"/>
<variable cmeta:id="id_00046" name="ENa" public_interface="out" units="millivolt"/>
<variable cmeta:id="id_00047" name="EK" public_interface="out" units="millivolt"/>
<variable name="EKs" public_interface="out" units="millivolt"/>
<variable cmeta:id="id_00048" name="nao" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00050" name="ko" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00049" name="nai" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00051" name="ki" public_interface="in" units="millimolar"/>
<variable name="R" public_interface="in" units="joule_per_kilomole_kelvin"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="F" public_interface="in" units="coulomb_per_mole"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ENa</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>nao</ci>
<ci>nai</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>EK</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>ko</ci>
<ci>ki</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>EKs</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<apply>
<plus/>
<ci>ko</ci>
<apply>
<times/>
<ci>PKNa</ci>
<ci>nao</ci>
</apply>
</apply>
<apply>
<plus/>
<ci>ki</ci>
<apply>
<times/>
<ci>PKNa</ci>
<ci>nai</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00035" name="INa">
<variable name="mss" units="dimensionless"/>
<variable name="tm" public_interface="out" units="millisecond"/>
<variable initial_value="39.57" name="mssV1" units="millivolt"/>
<variable initial_value="9.871" name="mssV2" units="millivolt"/>
<variable initial_value="11.64" name="mtV1" units="millivolt"/>
<variable initial_value="34.77" name="mtV2" units="millivolt"/>
<variable initial_value="6.765" name="mtD1" units="dimensionless"/>
<variable initial_value="8.552" name="mtD2" units="dimensionless"/>
<variable initial_value="77.42" name="mtV3" units="millivolt"/>
<variable initial_value="5.955" name="mtV4" units="millivolt"/>
<variable initial_value="0" name="m" units="dimensionless"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="hss" units="dimensionless"/>
<variable name="thf" units="millisecond"/>
<variable name="ths" units="millisecond"/>
<variable initial_value="82.9" name="hssV1" units="millivolt"/>
<variable initial_value="6.086" name="hssV2" units="millivolt"/>
<variable name="Ahs" units="dimensionless"/>
<variable initial_value="0.99" name="Ahf" units="dimensionless"/>
<variable initial_value="1" name="hf" units="dimensionless"/>
<variable initial_value="1" name="hs" units="dimensionless"/>
<variable name="h" units="dimensionless"/>
<variable initial_value="75" name="GNa" units="milliS_per_microF"/>
<variable name="jss" units="dimensionless"/>
<variable name="tj" units="millisecond"/>
<variable initial_value="1" name="j" units="dimensionless"/>
<variable name="hssp" units="dimensionless"/>
<variable name="thsp" units="millisecond"/>
<variable initial_value="1" name="hsp" units="dimensionless"/>
<variable name="hp" units="dimensionless"/>
<variable name="tjp" units="millisecond"/>
<variable initial_value="1" name="jp" units="dimensionless"/>
<variable name="fINap" units="dimensionless"/>
<variable name="INa" public_interface="out" units="microA_per_microF"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="KmCaMK" public_interface="in" units="millimolar"/>
<variable name="CaMKa" public_interface="in" units="millimolar"/>
<variable name="ENa" public_interface="in" units="millivolt"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>mss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<ci>mssV1</ci>
</apply>
</apply>
<ci>mssV2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tm</ci>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<ci>mtD1</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<ci>mtV1</ci>
</apply>
<ci>mtV2</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>mtD2</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<ci>mtV3</ci>
</apply>
</apply>
<ci>mtV4</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>m</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>mss</ci>
<ci>m</ci>
</apply>
<ci>tm</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>hss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<ci>hssV1</ci>
</apply>
<ci>hssV2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>thf</ci>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn type="e-notation" cellml:units="dimensionless">1.432 <sep/>
-5</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">1.196</cn>
</apply>
</apply>
<cn cellml:units="millivolt">6.285</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">6.149</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">0.5096</cn>
</apply>
<cn cellml:units="millivolt">20.27</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ths</ci>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.009794</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">17.95</cn>
</apply>
</apply>
<cn cellml:units="millivolt">28.05</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.3343</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">5.73</cn>
</apply>
<cn cellml:units="millivolt">56.66</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Ahs</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>Ahf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>hf</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>hss</ci>
<ci>hf</ci>
</apply>
<ci>thf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>hs</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>hss</ci>
<ci>hs</ci>
</apply>
<ci>ths</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Ahf</ci>
<ci>hf</ci>
</apply>
<apply>
<times/>
<ci>Ahs</ci>
<ci>hs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>jss</ci>
<ci>hss</ci>
</apply>
<apply>
<eq/>
<ci>tj</ci>
<apply>
<plus/>
<cn cellml:units="millisecond">2.038</cn>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.02136</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">100.6</cn>
</apply>
</apply>
<cn cellml:units="millivolt">8.281</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.3052</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">0.9941</cn>
</apply>
<cn cellml:units="millivolt">38.45</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>j</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>jss</ci>
<ci>j</ci>
</apply>
<ci>tj</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>hssp</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">89.1</cn>
</apply>
<cn cellml:units="millivolt">6.086</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>thsp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>ths</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>hsp</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>hssp</ci>
<ci>hsp</ci>
</apply>
<ci>thsp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>hp</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Ahf</ci>
<ci>hf</ci>
</apply>
<apply>
<times/>
<ci>Ahs</ci>
<ci>hsp</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tjp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1.46</cn>
<ci>tj</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>jp</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>jss</ci>
<ci>jp</ci>
</apply>
<ci>tjp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fINap</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>KmCaMK</ci>
<ci>CaMKa</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INa</ci>
<apply>
<times/>
<ci>GNa</ci>
<apply>
<minus/>
<ci>v</ci>
<ci>ENa</ci>
</apply>
<apply>
<power/>
<ci>m</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fINap</ci>
</apply>
<ci>h</ci>
<ci>j</ci>
</apply>
<apply>
<times/>
<ci>fINap</ci>
<ci>hp</ci>
<ci>jp</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00103" name="INaL">
<variable name="mLss" units="dimensionless"/>
<variable name="tm" public_interface="in" units="millisecond"/>
<variable name="tmL" units="millisecond"/>
<variable initial_value="0" name="mL" units="dimensionless"/>
<variable initial_value="200" name="thL" units="millisecond"/>
<variable name="hLss" units="dimensionless"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable initial_value="1" name="hL" units="dimensionless"/>
<variable name="hLssp" units="dimensionless"/>
<variable name="thLp" units="millisecond"/>
<variable initial_value="1" name="hLp" units="dimensionless"/>
<variable initial_value="0.0075" name="GNaL_b" units="milliS_per_microF"/>
<variable name="GNaL" units="milliS_per_microF"/>
<variable name="fINaLp" units="dimensionless"/>
<variable cmeta:id="id_00105" name="KmCaMK" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00104" name="CaMKa" public_interface="in" units="millimolar"/>
<variable name="ENa" public_interface="in" units="millivolt"/>
<variable name="INaL" public_interface="out" units="microA_per_microF"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="time" public_interface="in" units="millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>mLss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">42.85</cn>
</apply>
</apply>
<cn cellml:units="millivolt">5.264</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tmL</ci>
<ci>tm</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>mL</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>mLss</ci>
<ci>mL</ci>
</apply>
<ci>tmL</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>hLss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">87.61</cn>
</apply>
<cn cellml:units="millivolt">7.488</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>hL</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>hLss</ci>
<ci>hL</ci>
</apply>
<ci>thL</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>hLssp</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
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<ci>i</ci>
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<ci>assp</ci>
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<ci>dti_develop</ci>
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<minus/>
<ci>v</ci>
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<ci>dti_develop</ci>
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<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
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</apply>
</apply>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
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<apply>
<times/>
<cn cellml:units="dimensionless">0.0045</cn>
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<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">20</cn>
</apply>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tfs</ci>
<apply>
<plus/>
<cn cellml:units="millisecond">1000</cn>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
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<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.000035</cn>
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<exp/>
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<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
<cn cellml:units="millivolt">4</cn>
</apply>
</apply>
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<apply>
<times/>
<cn cellml:units="dimensionless">0.000035</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">5</cn>
</apply>
<cn cellml:units="millivolt">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Aff</ci>
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</apply>
<apply>
<eq/>
<ci>Afs</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>Aff</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>ff</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fss</ci>
<ci>ff</ci>
</apply>
<ci>tff</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fs</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fss</ci>
<ci>fs</ci>
</apply>
<ci>tfs</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>f</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Aff</ci>
<ci>ff</ci>
</apply>
<apply>
<times/>
<ci>Afs</ci>
<ci>fs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>fcass</ci>
<ci>fss</ci>
</apply>
<apply>
<eq/>
<ci>tfcaf</ci>
<apply>
<plus/>
<cn cellml:units="millisecond">7</cn>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.04</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>v</ci>
<cn cellml:units="millivolt">4</cn>
</apply>
</apply>
<cn cellml:units="millivolt">7</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.04</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>v</ci>
<cn cellml:units="millivolt">4</cn>
</apply>
<cn cellml:units="millivolt">7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tfcas</ci>
<apply>
<plus/>
<cn cellml:units="millisecond">100</cn>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.00012</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>v</ci>
</apply>
<cn cellml:units="millivolt">3</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.00012</cn>
<apply>
<exp/>
<apply>
<divide/>
<ci>v</ci>
<cn cellml:units="millivolt">7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Afcaf</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">0.3</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.6</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>v</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Afcas</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>Afcaf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fcaf</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fcass</ci>
<ci>fcaf</ci>
</apply>
<ci>tfcaf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fcas</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fcass</ci>
<ci>fcas</ci>
</apply>
<ci>tfcas</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fca</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Afcaf</ci>
<ci>fcaf</ci>
</apply>
<apply>
<times/>
<ci>Afcas</ci>
<ci>fcas</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tjca</ci>
<cn cellml:units="millisecond">75</cn>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>jca</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fcass</ci>
<ci>jca</ci>
</apply>
<ci>tjca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>tffp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2.5</cn>
<ci>tff</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>ffp</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fss</ci>
<ci>ffp</ci>
</apply>
<ci>tffp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fp</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Aff</ci>
<ci>ffp</ci>
</apply>
<apply>
<times/>
<ci>Afs</ci>
<ci>fs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tfcafp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2.5</cn>
<ci>tfcaf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fcafp</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>fcass</ci>
<ci>fcafp</ci>
</apply>
<ci>tfcafp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fcap</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Afcaf</ci>
<ci>fcafp</ci>
</apply>
<apply>
<times/>
<ci>Afcas</ci>
<ci>fcas</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>km2n</ci>
<apply>
<times/>
<ci>jca</ci>
<cn cellml:units="per_millisecond">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>anca</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<apply>
<divide/>
<ci>k2n</ci>
<ci>km2n</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>Kmn</ci>
<ci>cass</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">4</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>nca</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>anca</ci>
<ci>k2n</ci>
</apply>
<apply>
<times/>
<ci>nca</ci>
<ci>km2n</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>PhiCaL</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt">4</cn>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>cass</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vfrt</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="per_millimolar">0.341</cn>
<ci>cao</ci>
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</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vfrt</ci>
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<cn cellml:units="dimensionless">1</cn>
</apply>
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<apply>
<eq/>
<ci>PhiCaNa</ci>
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<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>nass</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vfrt</ci>
</apply>
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<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>nao</ci>
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<minus/>
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<exp/>
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<cn cellml:units="dimensionless">1</cn>
<ci>vfrt</ci>
</apply>
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<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
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<apply>
<eq/>
<ci>PhiCaK</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
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<cn cellml:units="dimensionless">0.75</cn>
<ci>kss</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vfrt</ci>
</apply>
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<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>ko</ci>
</apply>
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</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>vfrt</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>PCa</ci>
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<piece>
<apply>
<times/>
<ci>PCa_b</ci>
<cn cellml:units="dimensionless">1.2</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
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<piece>
<apply>
<times/>
<ci>PCa_b</ci>
<cn cellml:units="dimensionless">2.5</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<ci>PCa_b</ci>
</otherwise>
</piecewise>
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<apply>
<eq/>
<ci>PCap</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1.1</cn>
<ci>PCa</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>PCaNa</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.00125</cn>
<ci>PCa</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>PCaK</ci>
<apply>
<times/>
<cn type="e-notation" cellml:units="dimensionless">3.574 <sep/>
-4</cn>
<ci>PCa</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>PCaNap</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.00125</cn>
<ci>PCap</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>PCaKp</ci>
<apply>
<times/>
<cn type="e-notation" cellml:units="dimensionless">3.574 <sep/>
-4</cn>
<ci>PCap</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fICaLp</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>KmCaMK</ci>
<ci>CaMKa</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL</ci>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fICaLp</ci>
</apply>
<ci>PCa</ci>
<ci>PhiCaL</ci>
<ci>d</ci>
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<plus/>
<apply>
<times/>
<ci>f</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
</apply>
</apply>
<apply>
<times/>
<ci>jca</ci>
<ci>fca</ci>
<ci>nca</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>fICaLp</ci>
<ci>PCap</ci>
<ci>PhiCaL</ci>
<ci>d</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>fp</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
</apply>
</apply>
<apply>
<times/>
<ci>jca</ci>
<ci>fcap</ci>
<ci>nca</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaNa</ci>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fICaLp</ci>
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<ci>PCaNa</ci>
<ci>PhiCaNa</ci>
<ci>d</ci>
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<plus/>
<apply>
<times/>
<ci>f</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
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<apply>
<times/>
<ci>jca</ci>
<ci>fca</ci>
<ci>nca</ci>
</apply>
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<apply>
<times/>
<ci>fICaLp</ci>
<ci>PCaNap</ci>
<ci>PhiCaNa</ci>
<ci>d</ci>
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<plus/>
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<ci>fp</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
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<ci>jca</ci>
<ci>fcap</ci>
<ci>nca</ci>
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<apply>
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<ci>ICaK</ci>
<apply>
<plus/>
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<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fICaLp</ci>
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<ci>PCaK</ci>
<ci>PhiCaK</ci>
<ci>d</ci>
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<plus/>
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<times/>
<ci>f</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
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<times/>
<ci>jca</ci>
<ci>fca</ci>
<ci>nca</ci>
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<times/>
<ci>fICaLp</ci>
<ci>PCaKp</ci>
<ci>PhiCaK</ci>
<ci>d</ci>
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<plus/>
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<times/>
<ci>fp</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>nca</ci>
</apply>
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<apply>
<times/>
<ci>jca</ci>
<ci>fcap</ci>
<ci>nca</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00028" name="IKr">
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<variable name="GKr" units="milliS_per_microF"/>
<variable name="xrss" units="dimensionless"/>
<variable name="txrf" units="millisecond"/>
<variable name="txrs" units="millisecond"/>
<variable name="Axrf" units="dimensionless"/>
<variable name="Axrs" units="dimensionless"/>
<variable initial_value="0" name="xrf" units="dimensionless"/>
<variable initial_value="0" name="xrs" units="dimensionless"/>
<variable name="xr" units="dimensionless"/>
<variable name="rkr" units="dimensionless"/>
<variable name="v" public_interface="in" units="millivolt"/>
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<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="EK" public_interface="in" units="millivolt"/>
<variable name="ko" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00030" name="IKr" public_interface="out" units="microA_per_microF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
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<eq/>
<ci>xrss</ci>
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<divide/>
<cn cellml:units="dimensionless">1</cn>
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<plus/>
<cn cellml:units="dimensionless">1</cn>
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<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
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<cn cellml:units="millivolt">6.789</cn>
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<apply>
<eq/>
<ci>txrf</ci>
<apply>
<plus/>
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<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
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<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.3652</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>v</ci>
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<cn cellml:units="millivolt">3.869</cn>
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<times/>
<cn type="e-notation" cellml:units="dimensionless">4.123 <sep/>
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<apply>
<exp/>
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<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>v</ci>
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</apply>
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<cn cellml:units="millivolt">20.38</cn>
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</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>txrs</ci>
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<plus/>
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<divide/>
<cn cellml:units="millisecond">1</cn>
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<cn cellml:units="dimensionless">0.06629</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>v</ci>
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<cn cellml:units="millivolt">7.355</cn>
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<times/>
<cn type="e-notation" cellml:units="dimensionless">1.128 <sep/>
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<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>v</ci>
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<cn cellml:units="millivolt">25.94</cn>
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</apply>
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<apply>
<eq/>
<ci>Axrf</ci>
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<divide/>
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<plus/>
<cn cellml:units="dimensionless">1</cn>
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<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">54.81</cn>
</apply>
<cn cellml:units="millivolt">38.21</cn>
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</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Axrs</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>Axrf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xrf</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>xrss</ci>
<ci>xrf</ci>
</apply>
<ci>txrf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xrs</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>xrss</ci>
<ci>xrs</ci>
</apply>
<ci>txrs</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>xr</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Axrf</ci>
<ci>xrf</ci>
</apply>
<apply>
<times/>
<ci>Axrs</ci>
<ci>xrs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>rkr</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">55</cn>
</apply>
<cn cellml:units="millivolt">75</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>v</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<cn cellml:units="millivolt">30</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>GKr</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>GKr_b</ci>
<cn cellml:units="dimensionless">1.3</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<piece>
<apply>
<times/>
<ci>GKr_b</ci>
<cn cellml:units="dimensionless">0.8</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<ci>GKr_b</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>IKr</ci>
<apply>
<times/>
<ci>GKr</ci>
<apply>
<root/>
<apply>
<divide/>
<ci>ko</ci>
<cn cellml:units="millimolar">5.4</cn>
</apply>
</apply>
<ci>xr</ci>
<ci>rkr</ci>
<apply>
<minus/>
<ci>v</ci>
<ci>EK</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00029" name="IKs">
<variable initial_value="0.0034" name="GKs_b" units="milliS_per_microF"/>
<variable name="GKs" units="milliS_per_microF"/>
<variable name="xs1ss" units="dimensionless"/>
<variable name="xs2ss" units="dimensionless"/>
<variable name="txs1" units="millisecond"/>
<variable initial_value="0" name="xs1" units="dimensionless"/>
<variable initial_value="0" name="xs2" units="dimensionless"/>
<variable name="KsCa" units="dimensionless"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="EKs" public_interface="in" units="millivolt"/>
<variable cmeta:id="id_00031" name="IKs" public_interface="out" units="microA_per_microF"/>
<variable name="txs2" units="millisecond"/>
<variable name="cai" public_interface="in" units="millimolar"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>xs1ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">11.6</cn>
</apply>
</apply>
<cn cellml:units="millivolt">8.932</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>txs1</ci>
<apply>
<plus/>
<cn cellml:units="millisecond">817.3</cn>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn type="e-notation" cellml:units="dimensionless">2.326 <sep/>
-4</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">48.28</cn>
</apply>
<cn cellml:units="millivolt">17.8</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.001292</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">210</cn>
</apply>
</apply>
<cn cellml:units="millivolt">230</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xs1</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>xs1ss</ci>
<ci>xs1</ci>
</apply>
<ci>txs1</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>xs2ss</ci>
<ci>xs1ss</ci>
</apply>
<apply>
<eq/>
<ci>txs2</ci>
<apply>
<divide/>
<cn cellml:units="millisecond">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.01</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>v</ci>
<cn cellml:units="millivolt">50</cn>
</apply>
<cn cellml:units="millivolt">20</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0193</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">66.54</cn>
</apply>
</apply>
<cn cellml:units="millivolt">31</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xs2</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>xs2ss</ci>
<ci>xs2</ci>
</apply>
<ci>txs2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>KsCa</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.6</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn type="e-notation" cellml:units="millimolar">3.8 <sep/>
-5</cn>
<ci>cai</ci>
</apply>
<cn cellml:units="dimensionless">1.4</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>GKs</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>GKs_b</ci>
<cn cellml:units="dimensionless">1.4</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<ci>GKs_b</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>IKs</ci>
<apply>
<times/>
<ci>GKs</ci>
<ci>KsCa</ci>
<ci>xs1</ci>
<ci>xs2</ci>
<apply>
<minus/>
<ci>v</ci>
<ci>EKs</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00026" name="IK1">
<variable name="GK1" units="milliS_per_microF"/>
<variable initial_value="0.1908" name="GK1_b" units="milliS_per_microF"/>
<variable name="xk1ss" units="dimensionless"/>
<variable name="txk1" units="millisecond"/>
<variable initial_value="1" name="xk1" units="dimensionless"/>
<variable name="rk1" units="millisecond"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="EK" public_interface="in" units="millivolt"/>
<variable name="ko" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00027" name="IK1" public_interface="out" units="microA_per_microF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>xk1ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<apply>
<times/>
<cn cellml:units="millivolt_per_millimole">2.5538</cn>
<ci>ko</ci>
</apply>
<cn cellml:units="millivolt">144.59</cn>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="millivolt_per_millimole">1.5692</cn>
<ci>ko</ci>
</apply>
<cn cellml:units="millivolt">3.8115</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>txk1</ci>
<apply>
<divide/>
<cn cellml:units="millisecond">122.2</cn>
<apply>
<plus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">127.2</cn>
</apply>
</apply>
<cn cellml:units="millivolt">20.36</cn>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">236.8</cn>
</apply>
<cn cellml:units="millivolt">69.33</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xk1</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>xk1ss</ci>
<ci>xk1</ci>
</apply>
<ci>txk1</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>rk1</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>v</ci>
<cn cellml:units="millivolt">105.8</cn>
</apply>
<apply>
<times/>
<cn cellml:units="millivolt_per_millimole">2.6</cn>
<ci>ko</ci>
</apply>
</apply>
<cn cellml:units="millivolt">9.493</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>GK1</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>GK1_b</ci>
<cn cellml:units="dimensionless">1.2</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<piece>
<apply>
<times/>
<ci>GK1_b</ci>
<cn cellml:units="dimensionless">1.3</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<ci>GK1_b</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>IK1</ci>
<apply>
<times/>
<ci>GK1</ci>
<apply>
<root/>
<ci>ko</ci>
</apply>
<ci>rk1</ci>
<ci>xk1</ci>
<apply>
<minus/>
<ci>v</ci>
<ci>EK</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00025" name="INaCa_i">
<variable initial_value="15" name="kna1" units="per_millisecond"/>
<variable initial_value="5" name="kna2" units="per_millisecond"/>
<variable initial_value="88.12" name="kna3" units="per_millisecond"/>
<variable initial_value="12.5" name="kasymm" units="dimensionless"/>
<variable initial_value="6e4" name="wna" units="dimensionless"/>
<variable initial_value="6e4" name="wca" units="dimensionless"/>
<variable initial_value="5e3" name="wnaca" units="dimensionless"/>
<variable initial_value="1.5e6" name="kcaon" units="per_millisecond"/>
<variable initial_value="5e3" name="kcaoff" units="per_millisecond"/>
<variable initial_value="0.5224" name="qna" units="dimensionless"/>
<variable initial_value="0.167" name="qca" units="dimensionless"/>
<variable name="hna" units="dimensionless"/>
<variable name="hca" units="dimensionless"/>
<variable name="zca" public_interface="in" units="dimensionless"/>
<variable initial_value="150e-6" name="KmCaAct" units="millimolar"/>
<variable name="zna" public_interface="in" units="dimensionless"/>
<variable initial_value="0.0008" name="Gncx_b" units="milliS_per_microF"/>
<variable name="Gncx" units="milliS_per_microF"/>
<variable name="R" public_interface="in" units="joule_per_kilomole_kelvin"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="F" public_interface="in" units="coulomb_per_mole"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="nai" public_interface="in" units="millimolar"/>
<variable name="nass" public_interface="in" units="millimolar"/>
<variable name="cass" public_interface="in" units="millimolar"/>
<variable name="nao" public_interface="in" units="millimolar"/>
<variable name="cai" public_interface="in" units="millimolar"/>
<variable name="cao" public_interface="in" units="millimolar"/>
<variable name="h1_i" units="dimensionless"/>
<variable name="h2_i" units="dimensionless"/>
<variable name="h3_i" units="dimensionless"/>
<variable name="h4_i" units="dimensionless"/>
<variable name="h5_i" units="dimensionless"/>
<variable name="h6_i" units="dimensionless"/>
<variable name="h7_i" units="dimensionless"/>
<variable name="h8_i" units="dimensionless"/>
<variable name="h9_i" units="dimensionless"/>
<variable name="h10_i" units="dimensionless"/>
<variable name="h11_i" units="dimensionless"/>
<variable name="h12_i" units="dimensionless"/>
<variable name="k1_i" units="dimensionless"/>
<variable name="k2_i" units="dimensionless"/>
<variable name="k3p_i" units="dimensionless"/>
<variable name="k3pp_i" units="dimensionless"/>
<variable name="k3_i" units="dimensionless"/>
<variable name="k4_i" units="dimensionless"/>
<variable name="k4p_i" units="dimensionless"/>
<variable name="k4pp_i" units="dimensionless"/>
<variable name="k5_i" units="dimensionless"/>
<variable name="k6_i" units="dimensionless"/>
<variable name="k7_i" units="dimensionless"/>
<variable name="k8_i" units="dimensionless"/>
<variable name="x1_i" units="dimensionless"/>
<variable name="x2_i" units="dimensionless"/>
<variable name="x3_i" units="dimensionless"/>
<variable name="x4_i" units="dimensionless"/>
<variable name="E1_i" units="dimensionless"/>
<variable name="E2_i" units="dimensionless"/>
<variable name="E3_i" units="dimensionless"/>
<variable name="E4_i" units="dimensionless"/>
<variable name="allo_i" units="dimensionless"/>
<variable name="JncxNa_i" units="millimolar_per_millisecond"/>
<variable name="JncxCa_i" units="millimolar_per_millisecond"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="INaCa_i" public_interface="out" units="microA_per_microF"/>
<variable name="INaCa_ss" public_interface="out" units="microA_per_microF"/>
<variable name="h1_ss" units="dimensionless"/>
<variable name="h2_ss" units="dimensionless"/>
<variable name="h3_ss" units="dimensionless"/>
<variable name="h4_ss" units="dimensionless"/>
<variable name="h5_ss" units="dimensionless"/>
<variable name="h6_ss" units="dimensionless"/>
<variable name="h7_ss" units="dimensionless"/>
<variable name="h8_ss" units="dimensionless"/>
<variable name="h9_ss" units="dimensionless"/>
<variable name="h10_ss" units="dimensionless"/>
<variable name="h11_ss" units="dimensionless"/>
<variable name="h12_ss" units="dimensionless"/>
<variable name="k1_ss" units="dimensionless"/>
<variable name="k2_ss" units="dimensionless"/>
<variable name="k3p_ss" units="dimensionless"/>
<variable name="k3pp_ss" units="dimensionless"/>
<variable name="k3_ss" units="dimensionless"/>
<variable name="k4_ss" units="dimensionless"/>
<variable name="k4p_ss" units="dimensionless"/>
<variable name="k4pp_ss" units="dimensionless"/>
<variable name="k5_ss" units="dimensionless"/>
<variable name="k6_ss" units="dimensionless"/>
<variable name="k7_ss" units="dimensionless"/>
<variable name="k8_ss" units="dimensionless"/>
<variable name="x1_ss" units="dimensionless"/>
<variable name="x2_ss" units="dimensionless"/>
<variable name="x3_ss" units="dimensionless"/>
<variable name="x4_ss" units="dimensionless"/>
<variable name="E1_ss" units="dimensionless"/>
<variable name="E2_ss" units="dimensionless"/>
<variable name="E3_ss" units="dimensionless"/>
<variable name="E4_ss" units="dimensionless"/>
<variable name="allo_ss" units="dimensionless"/>
<variable name="JncxNa_ss" units="millimolar_per_millisecond"/>
<variable name="JncxCa_ss" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>hca</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>qca</ci>
<ci>v</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>hna</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>qna</ci>
<ci>v</ci>
<ci>F</ci>
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<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h1_i</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nai</ci>
<ci>kna3</ci>
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<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<ci>hna</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h2_i</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nai</ci>
<ci>hna</ci>
</apply>
<apply>
<times/>
<ci>kna3</ci>
<ci>h1_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h3_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h1_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h4_i</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nai</ci>
<ci>kna1</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nai</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h5_i</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nai</ci>
<ci>nai</ci>
</apply>
<apply>
<times/>
<ci>h4_i</ci>
<ci>kna1</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h6_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h4_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h7_i</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>hna</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h8_i</ci>
<apply>
<divide/>
<ci>nao</ci>
<apply>
<times/>
<ci>kna3</ci>
<ci>hna</ci>
<ci>h7_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h9_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h7_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h10_i</ci>
<apply>
<plus/>
<ci>kasymm</ci>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna1</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h11_i</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nao</ci>
<ci>nao</ci>
</apply>
<apply>
<times/>
<ci>h10_i</ci>
<ci>kna1</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h12_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h10_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k1_i</ci>
<apply>
<times/>
<ci>h12_i</ci>
<ci>cao</ci>
<ci>kcaon</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k2_i</ci>
<ci>kcaoff</ci>
</apply>
<apply>
<eq/>
<ci>k3p_i</ci>
<apply>
<times/>
<ci>h9_i</ci>
<ci>wca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k3pp_i</ci>
<apply>
<times/>
<ci>h8_i</ci>
<ci>wnaca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k3_i</ci>
<apply>
<plus/>
<ci>k3p_i</ci>
<ci>k3pp_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4p_i</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>h3_i</ci>
<ci>wca</ci>
</apply>
<ci>hca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4pp_i</ci>
<apply>
<times/>
<ci>h2_i</ci>
<ci>wnaca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4_i</ci>
<apply>
<plus/>
<ci>k4p_i</ci>
<ci>k4pp_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k5_i</ci>
<ci>kcaoff</ci>
</apply>
<apply>
<eq/>
<ci>k6_i</ci>
<apply>
<times/>
<ci>h6_i</ci>
<ci>cai</ci>
<ci>kcaon</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k7_i</ci>
<apply>
<times/>
<ci>h5_i</ci>
<ci>h2_i</ci>
<ci>wna</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k8_i</ci>
<apply>
<times/>
<ci>h8_i</ci>
<ci>h11_i</ci>
<ci>wna</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>x1_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k2_i</ci>
<ci>k4_i</ci>
<apply>
<plus/>
<ci>k7_i</ci>
<ci>k6_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k5_i</ci>
<ci>k7_i</ci>
<apply>
<plus/>
<ci>k2_i</ci>
<ci>k3_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x2_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k1_i</ci>
<ci>k7_i</ci>
<apply>
<plus/>
<ci>k4_i</ci>
<ci>k5_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k4_i</ci>
<ci>k6_i</ci>
<apply>
<plus/>
<ci>k1_i</ci>
<ci>k8_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x3_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k1_i</ci>
<ci>k3_i</ci>
<apply>
<plus/>
<ci>k7_i</ci>
<ci>k6_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k8_i</ci>
<ci>k6_i</ci>
<apply>
<plus/>
<ci>k2_i</ci>
<ci>k3_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x4_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k2_i</ci>
<ci>k8_i</ci>
<apply>
<plus/>
<ci>k4_i</ci>
<ci>k5_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k3_i</ci>
<ci>k5_i</ci>
<apply>
<plus/>
<ci>k1_i</ci>
<ci>k8_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E1_i</ci>
<apply>
<divide/>
<ci>x1_i</ci>
<apply>
<plus/>
<ci>x1_i</ci>
<ci>x2_i</ci>
<ci>x3_i</ci>
<ci>x4_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E2_i</ci>
<apply>
<divide/>
<ci>x2_i</ci>
<apply>
<plus/>
<ci>x1_i</ci>
<ci>x2_i</ci>
<ci>x3_i</ci>
<ci>x4_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E3_i</ci>
<apply>
<divide/>
<ci>x3_i</ci>
<apply>
<plus/>
<ci>x1_i</ci>
<ci>x2_i</ci>
<ci>x3_i</ci>
<ci>x4_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E4_i</ci>
<apply>
<divide/>
<ci>x4_i</ci>
<apply>
<plus/>
<ci>x1_i</ci>
<ci>x2_i</ci>
<ci>x3_i</ci>
<ci>x4_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>allo_i</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>KmCaAct</ci>
<ci>cai</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JncxNa_i</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<apply>
<minus/>
<apply>
<times/>
<ci>E4_i</ci>
<ci>k7_i</ci>
</apply>
<apply>
<times/>
<ci>E1_i</ci>
<ci>k8_i</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>E3_i</ci>
<ci>k4pp_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>E2_i</ci>
<ci>k3pp_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JncxCa_i</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>E2_i</ci>
<ci>k2_i</ci>
</apply>
<apply>
<times/>
<ci>E1_i</ci>
<ci>k1_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Gncx</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>Gncx_b</ci>
<cn cellml:units="dimensionless">1.1</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<piece>
<apply>
<times/>
<ci>Gncx_b</ci>
<cn cellml:units="dimensionless">1.4</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<ci>Gncx_b</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>INaCa_i</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.8</cn>
<ci>Gncx</ci>
<ci>allo_i</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>zna</ci>
<ci>JncxNa_i</ci>
</apply>
<apply>
<times/>
<ci>zca</ci>
<ci>JncxCa_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h1_ss</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nass</ci>
<ci>kna3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<ci>hna</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h2_ss</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nass</ci>
<ci>hna</ci>
</apply>
<apply>
<times/>
<ci>kna3</ci>
<ci>h1_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h3_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h1_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h4_ss</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nass</ci>
<ci>kna1</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nass</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h5_ss</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nass</ci>
<ci>nass</ci>
</apply>
<apply>
<times/>
<ci>h4_ss</ci>
<ci>kna1</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h6_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h4_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h7_ss</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>hna</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h8_ss</ci>
<apply>
<divide/>
<ci>nao</ci>
<apply>
<times/>
<ci>kna3</ci>
<ci>hna</ci>
<ci>h7_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h9_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h7_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h10_ss</ci>
<apply>
<plus/>
<ci>kasymm</ci>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna1</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nao</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h11_ss</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nao</ci>
<ci>nao</ci>
</apply>
<apply>
<times/>
<ci>h10_ss</ci>
<ci>kna1</ci>
<ci>kna2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h12_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>h10_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k1_ss</ci>
<apply>
<times/>
<ci>h12_ss</ci>
<ci>cao</ci>
<ci>kcaon</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k2_ss</ci>
<ci>kcaoff</ci>
</apply>
<apply>
<eq/>
<ci>k3p_ss</ci>
<apply>
<times/>
<ci>h9_ss</ci>
<ci>wca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k3pp_ss</ci>
<apply>
<times/>
<ci>h8_ss</ci>
<ci>wnaca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k3_ss</ci>
<apply>
<plus/>
<ci>k3p_ss</ci>
<ci>k3pp_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4p_ss</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>h3_ss</ci>
<ci>wca</ci>
</apply>
<ci>hca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4pp_ss</ci>
<apply>
<times/>
<ci>h2_ss</ci>
<ci>wnaca</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k4_ss</ci>
<apply>
<plus/>
<ci>k4p_ss</ci>
<ci>k4pp_ss</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k5_ss</ci>
<ci>kcaoff</ci>
</apply>
<apply>
<eq/>
<ci>k6_ss</ci>
<apply>
<times/>
<ci>h6_ss</ci>
<ci>cass</ci>
<ci>kcaon</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k7_ss</ci>
<apply>
<times/>
<ci>h5_ss</ci>
<ci>h2_ss</ci>
<ci>wna</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k8_ss</ci>
<apply>
<times/>
<ci>h8_ss</ci>
<ci>h11_ss</ci>
<ci>wna</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>x1_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k2_ss</ci>
<ci>k4_ss</ci>
<apply>
<plus/>
<ci>k7_ss</ci>
<ci>k6_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k5_ss</ci>
<ci>k7_ss</ci>
<apply>
<plus/>
<ci>k2_ss</ci>
<ci>k3_ss</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x2_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k1_ss</ci>
<ci>k7_ss</ci>
<apply>
<plus/>
<ci>k4_ss</ci>
<ci>k5_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k4_ss</ci>
<ci>k6_ss</ci>
<apply>
<plus/>
<ci>k1_ss</ci>
<ci>k8_ss</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x3_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k1_ss</ci>
<ci>k3_ss</ci>
<apply>
<plus/>
<ci>k7_ss</ci>
<ci>k6_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k8_ss</ci>
<ci>k6_ss</ci>
<apply>
<plus/>
<ci>k2_ss</ci>
<ci>k3_ss</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x4_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>k2_ss</ci>
<ci>k8_ss</ci>
<apply>
<plus/>
<ci>k4_ss</ci>
<ci>k5_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k3_ss</ci>
<ci>k5_ss</ci>
<apply>
<plus/>
<ci>k1_ss</ci>
<ci>k8_ss</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E1_ss</ci>
<apply>
<divide/>
<ci>x1_ss</ci>
<apply>
<plus/>
<ci>x1_ss</ci>
<ci>x2_ss</ci>
<ci>x3_ss</ci>
<ci>x4_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E2_ss</ci>
<apply>
<divide/>
<ci>x2_ss</ci>
<apply>
<plus/>
<ci>x1_ss</ci>
<ci>x2_ss</ci>
<ci>x3_ss</ci>
<ci>x4_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E3_ss</ci>
<apply>
<divide/>
<ci>x3_ss</ci>
<apply>
<plus/>
<ci>x1_ss</ci>
<ci>x2_ss</ci>
<ci>x3_ss</ci>
<ci>x4_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E4_ss</ci>
<apply>
<divide/>
<ci>x4_ss</ci>
<apply>
<plus/>
<ci>x1_ss</ci>
<ci>x2_ss</ci>
<ci>x3_ss</ci>
<ci>x4_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>allo_ss</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>KmCaAct</ci>
<ci>cass</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JncxNa_ss</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<apply>
<minus/>
<apply>
<times/>
<ci>E4_ss</ci>
<ci>k7_ss</ci>
</apply>
<apply>
<times/>
<ci>E1_ss</ci>
<ci>k8_ss</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>E3_ss</ci>
<ci>k4pp_ss</ci>
</apply>
</apply>
<apply>
<times/>
<ci>E2_ss</ci>
<ci>k3pp_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JncxCa_ss</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>E2_ss</ci>
<ci>k2_ss</ci>
</apply>
<apply>
<times/>
<ci>E1_ss</ci>
<ci>k1_ss</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INaCa_ss</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.2</cn>
<ci>Gncx</ci>
<ci>allo_ss</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>zna</ci>
<ci>JncxNa_ss</ci>
</apply>
<apply>
<times/>
<ci>zca</ci>
<ci>JncxCa_ss</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00106" name="INaK">
<variable initial_value="949.5" name="k1p" units="per_millisecond"/>
<variable initial_value="182.4" name="k1m" units="per_millisecond"/>
<variable initial_value="687.2" name="k2p" units="per_millisecond"/>
<variable initial_value="39.4" name="k2m" units="per_millisecond"/>
<variable initial_value="1899" name="k3p" units="per_millisecond"/>
<variable initial_value="79300" name="k3m" units="per_millisecond"/>
<variable initial_value="639" name="k4p" units="per_millisecond"/>
<variable initial_value="40" name="k4m" units="per_millisecond"/>
<variable initial_value="9.073" name="Knai0" units="millimolar"/>
<variable initial_value="27.78" name="Knao0" units="millimolar"/>
<variable initial_value="-0.155" name="delta" units="millivolt"/>
<variable initial_value="0.5" name="Kki" units="per_millisecond"/>
<variable initial_value="0.3582" name="Kko" units="per_millisecond"/>
<variable initial_value="0.05" name="MgADP" units="millimolar"/>
<variable initial_value="9.8" name="MgATP" units="millimolar"/>
<variable initial_value="1.698e-7" name="Kmgatp" units="millimolar"/>
<variable initial_value="1e-7" name="H" units="millimolar"/>
<variable initial_value="4.2" name="eP" units="dimensionless"/>
<variable initial_value="1.698e-7" name="Khp" units="millimolar"/>
<variable initial_value="224" name="Knap" units="millimolar"/>
<variable initial_value="292" name="Kxkur" units="millimolar"/>
<variable name="zk" public_interface="in" units="dimensionless"/>
<variable name="zna" public_interface="in" units="dimensionless"/>
<variable initial_value="30" name="Pnak_b" units="milliS_per_microF"/>
<variable name="Pnak" units="milliS_per_microF"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="R" public_interface="in" units="joule_per_kilomole_kelvin"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="F" public_interface="in" units="coulomb_per_mole"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable name="nai" public_interface="in" units="millimolar"/>
<variable name="ki" public_interface="in" units="millimolar"/>
<variable name="nao" public_interface="in" units="millimolar"/>
<variable name="ko" public_interface="in" units="millimolar"/>
<variable name="Knai" units="millimolar"/>
<variable name="Knao" units="millimolar"/>
<variable name="P" units="dimensionless"/>
<variable name="a1" units="dimensionless"/>
<variable name="b1" units="dimensionless"/>
<variable name="a2" units="dimensionless"/>
<variable name="b2" units="dimensionless"/>
<variable name="a3" units="dimensionless"/>
<variable name="b3" units="dimensionless"/>
<variable name="a4" units="dimensionless"/>
<variable name="b4" units="dimensionless"/>
<variable name="x1" units="dimensionless"/>
<variable name="x2" units="dimensionless"/>
<variable name="x3" units="dimensionless"/>
<variable name="x4" units="dimensionless"/>
<variable name="E1" units="dimensionless"/>
<variable name="E2" units="dimensionless"/>
<variable name="E3" units="dimensionless"/>
<variable name="E4" units="dimensionless"/>
<variable name="JnakNa" units="millimolar_per_millisecond"/>
<variable name="JnakK" units="millimolar_per_millisecond"/>
<variable name="INaK" public_interface="out" units="microA_per_microF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Knai</ci>
<apply>
<times/>
<ci>Knai0</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>v</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Knao</ci>
<apply>
<times/>
<ci>Knao0</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>delta</ci>
</apply>
<ci>v</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>P</ci>
<apply>
<divide/>
<ci>eP</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>H</ci>
<ci>Khp</ci>
</apply>
<apply>
<divide/>
<ci>nai</ci>
<ci>Knap</ci>
</apply>
<apply>
<divide/>
<ci>ki</ci>
<ci>Kxkur</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>a1</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k1p</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>nai</ci>
<ci>Knai</ci>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nai</ci>
<ci>Knai</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>ki</ci>
<ci>Kki</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>b1</ci>
<apply>
<times/>
<ci>k1m</ci>
<ci>MgADP</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>a2</ci>
<ci>k2p</ci>
</apply>
<apply>
<eq/>
<ci>b2</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k2m</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>nao</ci>
<ci>Knao</ci>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nao</ci>
<ci>Knao</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>ko</ci>
<ci>Kko</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>a3</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k3p</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>ko</ci>
<ci>Kko</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nao</ci>
<ci>Knao</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>ko</ci>
<ci>Kko</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>b3</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k3m</ci>
<ci>P</ci>
<ci>H</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>MgATP</ci>
<ci>Kmgatp</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>a4</ci>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<ci>k4p</ci>
<ci>MgATP</ci>
</apply>
<ci>Kmgatp</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>MgATP</ci>
<ci>Kmgatp</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>b4</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k4m</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>ki</ci>
<ci>Kki</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>nai</ci>
<ci>Knai</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>ki</ci>
<ci>Kki</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x1</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>a4</ci>
<ci>a1</ci>
<ci>a2</ci>
</apply>
<apply>
<times/>
<ci>b2</ci>
<ci>b4</ci>
<ci>b3</ci>
</apply>
<apply>
<times/>
<ci>a2</ci>
<ci>b4</ci>
<ci>b3</ci>
</apply>
<apply>
<times/>
<ci>b3</ci>
<ci>a1</ci>
<ci>a2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x2</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>b2</ci>
<ci>b1</ci>
<ci>b4</ci>
</apply>
<apply>
<times/>
<ci>a1</ci>
<ci>a2</ci>
<ci>a3</ci>
</apply>
<apply>
<times/>
<ci>a3</ci>
<ci>b1</ci>
<ci>b4</ci>
</apply>
<apply>
<times/>
<ci>a2</ci>
<ci>a3</ci>
<ci>b4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x3</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>a2</ci>
<ci>a3</ci>
<ci>a4</ci>
</apply>
<apply>
<times/>
<ci>b3</ci>
<ci>b2</ci>
<ci>b1</ci>
</apply>
<apply>
<times/>
<ci>b2</ci>
<ci>b1</ci>
<ci>a4</ci>
</apply>
<apply>
<times/>
<ci>a3</ci>
<ci>a4</ci>
<ci>b1</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>x4</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>b4</ci>
<ci>b3</ci>
<ci>b2</ci>
</apply>
<apply>
<times/>
<ci>a3</ci>
<ci>a4</ci>
<ci>a1</ci>
</apply>
<apply>
<times/>
<ci>b2</ci>
<ci>a4</ci>
<ci>a1</ci>
</apply>
<apply>
<times/>
<ci>b3</ci>
<ci>b2</ci>
<ci>a1</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E1</ci>
<apply>
<divide/>
<ci>x1</ci>
<apply>
<plus/>
<ci>x1</ci>
<ci>x2</ci>
<ci>x3</ci>
<ci>x4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E2</ci>
<apply>
<divide/>
<ci>x2</ci>
<apply>
<plus/>
<ci>x1</ci>
<ci>x2</ci>
<ci>x3</ci>
<ci>x4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E3</ci>
<apply>
<divide/>
<ci>x3</ci>
<apply>
<plus/>
<ci>x1</ci>
<ci>x2</ci>
<ci>x3</ci>
<ci>x4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E4</ci>
<apply>
<divide/>
<ci>x4</ci>
<apply>
<plus/>
<ci>x1</ci>
<ci>x2</ci>
<ci>x3</ci>
<ci>x4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JnakNa</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<apply>
<minus/>
<apply>
<times/>
<ci>E1</ci>
<ci>a3</ci>
</apply>
<apply>
<times/>
<ci>E2</ci>
<ci>b3</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JnakK</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<apply>
<minus/>
<apply>
<times/>
<ci>E4</ci>
<ci>b1</ci>
</apply>
<apply>
<times/>
<ci>E3</ci>
<ci>a1</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Pnak</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>Pnak_b</ci>
<cn cellml:units="dimensionless">0.9</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<piece>
<apply>
<times/>
<ci>Pnak_b</ci>
<cn cellml:units="dimensionless">0.7</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<ci>Pnak_b</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>INaK</ci>
<apply>
<times/>
<ci>Pnak</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>zna</ci>
<ci>JnakNa</ci>
</apply>
<apply>
<times/>
<ci>zk</ci>
<ci>JnakK</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00020" name="IKb">
<variable name="xkb" units="dimensionless"/>
<variable cmeta:id="id_00021" initial_value="0.003" name="GKb_b" units="milliS_per_microF"/>
<variable cmeta:id="id_00022" name="GKb" units="milliS_per_microF"/>
<variable name="v" public_interface="in" units="millivolt"/>
<variable cmeta:id="id_00023" name="EK" public_interface="in" units="millivolt"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable cmeta:id="id_00024" name="IKb" public_interface="out" units="microA_per_microF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>xkb</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>v</ci>
<cn cellml:units="millivolt">14.48</cn>
</apply>
</apply>
<cn cellml:units="millivolt">18.34</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>GKb</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>GKb_b</ci>
<cn cellml:units="dimensionless">0.6</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<ci>GKb_b</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>IKb</ci>
<apply>
<times/>
<ci>GKb</ci>
<ci>xkb</ci>
<apply>
<minus/>
<ci>v</ci>
<ci>EK</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00017" name="INab">
<variable cmeta:id="id_00018" initial_value="3.75e-10" name="PNab" units="milliS_per_microF"/>
<variable cmeta:id="id_00019" name="INab" public_interface="out" units="microA_per_microF"/>
<variable name="nai" public_interface="in" units="millimolar"/>
<variable name="nao" public_interface="in" units="millimolar"/>
<variable name="vffrt" public_interface="in" units="coulomb_per_mole"/>
<variable name="vfrt" public_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INab</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>PNab</ci>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>nai</ci>
<apply>
<exp/>
<ci>vfrt</ci>
</apply>
</apply>
<ci>nao</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<ci>vfrt</ci>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00014" name="ICab">
<variable cmeta:id="id_00015" initial_value="2.5e-8" name="PCab" units="milliS_per_microF"/>
<variable cmeta:id="id_00016" name="ICab" public_interface="out" units="microA_per_microF"/>
<variable name="cai" public_interface="in" units="millimolar"/>
<variable name="cao" public_interface="in" units="millimolar"/>
<variable name="vffrt" public_interface="in" units="coulomb_per_mole"/>
<variable name="vfrt" public_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICab</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>PCab</ci>
<cn cellml:units="dimensionless">4</cn>
<ci>vffrt</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>cai</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vfrt</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.341</cn>
<ci>cao</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vfrt</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00010" name="IpCa">
<variable cmeta:id="id_00011" initial_value="0.0005" name="GpCa" units="milliS_per_microF"/>
<variable cmeta:id="id_00012" initial_value="0.0005" name="KmCap" units="millimolar"/>
<variable cmeta:id="id_00013" name="IpCa" public_interface="out" units="microA_per_microF"/>
<variable name="cai" public_interface="in" units="millimolar"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IpCa</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>GpCa</ci>
<ci>cai</ci>
</apply>
<apply>
<plus/>
<ci>KmCap</ci>
<ci>cai</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00107" name="diff">
<variable name="cai" public_interface="in" units="millimolar"/>
<variable name="cass" public_interface="in" units="millimolar"/>
<variable name="nai" public_interface="in" units="millimolar"/>
<variable name="nass" public_interface="in" units="millimolar"/>
<variable name="ki" public_interface="in" units="millimolar"/>
<variable name="kss" public_interface="in" units="millimolar"/>
<variable name="JdiffNa" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="Jdiff" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="JdiffK" public_interface="out" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>JdiffNa</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>nass</ci>
<ci>nai</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>JdiffK</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>kss</ci>
<ci>ki</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Jdiff</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>cass</ci>
<ci>cai</ci>
</apply>
<cn cellml:units="dimensionless">0.2</cn>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00005" name="ryr">
<variable initial_value="4.75" name="bt" units="millisecond"/>
<variable name="a_rel" units="millisecond"/>
<variable cmeta:id="id_00006" name="Jrel_inf" units="dimensionless"/>
<variable name="tau_rel" units="millisecond"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="ICaL" public_interface="in" units="microA_per_microF"/>
<variable name="cajsr" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00007" name="Jrel_infp" units="dimensionless"/>
<variable cmeta:id="id_00008" name="Jrel_temp" units="dimensionless"/>
<variable name="tau_relp" units="millisecond"/>
<variable initial_value="0" name="Jrelnp" units="dimensionless"/>
<variable initial_value="0" name="Jrelp" units="dimensionless"/>
<variable name="time" public_interface="in" units="millisecond"/>
<variable name="btp" units="millisecond"/>
<variable name="a_relp" units="millisecond"/>
<variable cmeta:id="id_00110" name="KmCaMK" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00109" name="CaMKa" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00009" name="Jrel_inf_temp" units="dimensionless"/>
<variable name="fJrelp" units="dimensionless"/>
<variable cmeta:id="id_00108" name="Jrel" public_interface="out" units="millimolar_per_millisecond"/>
<variable name="tau_rel_temp" units="millisecond"/>
<variable name="tau_relp_temp" units="millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>a_rel</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>bt</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Jrel_inf_temp</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>a_rel</ci>
<apply>
<minus/>
<ci>ICaL</ci>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="microA_per_microF">1</cn>
<apply>
<times/>
<cn cellml:units="microA_per_microF">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="millimolar">1.5</cn>
<ci>cajsr</ci>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Jrel_inf</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>Jrel_inf_temp</ci>
<cn cellml:units="dimensionless">1.7</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<ci>Jrel_inf_temp</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_rel_temp</ci>
<apply>
<divide/>
<ci>bt</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="millimolar">0.0123</cn>
<ci>cajsr</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_rel</ci>
<piecewise>
<piece>
<cn cellml:units="millisecond">0.001</cn>
<apply>
<lt/>
<ci>tau_rel_temp</ci>
<cn cellml:units="millisecond">0.001</cn>
</apply>
</piece>
<otherwise>
<ci>tau_rel_temp</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Jrelnp</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>Jrel_inf</ci>
<ci>Jrelnp</ci>
</apply>
<ci>tau_rel</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>btp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1.25</cn>
<ci>bt</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>a_relp</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>btp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Jrel_temp</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>a_relp</ci>
<apply>
<minus/>
<ci>ICaL</ci>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="millimolar">1.5</cn>
<ci>cajsr</ci>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Jrel_infp</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>Jrel_temp</ci>
<cn cellml:units="dimensionless">1.7</cn>
</apply>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<ci>Jrel_temp</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_relp_temp</ci>
<apply>
<divide/>
<ci>btp</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<cn cellml:units="millimolar">0.0123</cn>
<ci>cajsr</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_relp</ci>
<piecewise>
<piece>
<cn cellml:units="millisecond">0.001</cn>
<apply>
<lt/>
<ci>tau_relp_temp</ci>
<cn cellml:units="millisecond">0.001</cn>
</apply>
</piece>
<otherwise>
<ci>tau_relp_temp</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Jrelp</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>Jrel_infp</ci>
<ci>Jrelp</ci>
</apply>
<ci>tau_relp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>fJrelp</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>KmCaMK</ci>
<ci>CaMKa</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Jrel</ci>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fJrelp</ci>
</apply>
<ci>Jrelnp</ci>
</apply>
<apply>
<times/>
<ci>fJrelp</ci>
<ci>Jrelp</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00004" name="SERCA">
<variable name="upScale" units="dimensionless"/>
<variable name="Jupnp" units="millimolar_per_millisecond"/>
<variable name="Jupp" units="millimolar_per_millisecond"/>
<variable name="KmCaMK" public_interface="in" units="millimolar"/>
<variable name="CaMKa" public_interface="in" units="millimolar"/>
<variable name="celltype" public_interface="in" units="dimensionless"/>
<variable name="cai" public_interface="in" units="millimolar"/>
<variable name="cansr" public_interface="in" units="millimolar"/>
<variable name="fJupp" units="dimensionless"/>
<variable name="Jleak" units="millimolar_per_millisecond"/>
<variable name="Jup" public_interface="out" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>upScale</ci>
<piecewise>
<piece>
<cn cellml:units="dimensionless">1.3</cn>
<apply>
<eq/>
<ci>celltype</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<cn cellml:units="dimensionless">1</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>Jupnp</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>upScale</ci>
<cn cellml:units="dimensionless">0.004375</cn>
<ci>cai</ci>
</apply>
<apply>
<plus/>
<ci>cai</ci>
<cn cellml:units="millimolar">0.00092</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Jupp</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>upScale</ci>
<cn cellml:units="dimensionless">2.75</cn>
<cn cellml:units="dimensionless">0.004375</cn>
<ci>cai</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<ci>cai</ci>
<cn cellml:units="millimolar">0.00092</cn>
</apply>
<cn cellml:units="millimolar">0.00017</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>fJupp</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>KmCaMK</ci>
<ci>CaMKa</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Jleak</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="millimolar_per_millisecond">0.0039375</cn>
<ci>cansr</ci>
</apply>
<cn cellml:units="millimolar">15</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Jup</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>fJupp</ci>
</apply>
<ci>Jupnp</ci>
</apply>
<apply>
<times/>
<ci>fJupp</ci>
<ci>Jupp</ci>
</apply>
</apply>
<ci>Jleak</ci>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00111" name="trans_flux">
<variable name="cansr" public_interface="in" units="millimolar"/>
<variable cmeta:id="id_00112" name="cajsr" public_interface="in" units="millimolar"/>
<variable name="Jtr" public_interface="out" units="millimolar_per_millisecond"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Jtr</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>cansr</ci>
<ci>cajsr</ci>
</apply>
<cn cellml:units="millisecond">100</cn>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="intracellular_ions" component_2="INaL"/>
<map_variables variable_1="INaL" variable_2="INaL"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="membrane"/>
<map_variables variable_1="Istim" variable_2="Istim"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="trans_flux"/>
<map_variables variable_1="cajsr" variable_2="cajsr"/>
<map_variables variable_1="cansr" variable_2="cansr"/>
<map_variables variable_1="Jtr" variable_2="Jtr"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="SERCA"/>
<map_variables variable_1="cai" variable_2="cai"/>
<map_variables variable_1="cansr" variable_2="cansr"/>
<map_variables variable_1="Jup" variable_2="Jup"/>
</connection>
<connection>
<map_components component_1="SERCA" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
</connection>
<connection>
<map_components component_1="SERCA" component_2="CaMK"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="ryr"/>
<map_variables variable_1="cajsr" variable_2="cajsr"/>
<map_variables variable_1="Jrel" variable_2="Jrel"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="ryr"/>
<map_variables variable_1="ICaL" variable_2="ICaL"/>
</connection>
<connection>
<map_components component_1="ryr" component_2="CaMK"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="ryr" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="diff"/>
<map_variables variable_1="cai" variable_2="cai"/>
<map_variables variable_1="cass" variable_2="cass"/>
<map_variables variable_1="nai" variable_2="nai"/>
<map_variables variable_1="nass" variable_2="nass"/>
<map_variables variable_1="ki" variable_2="ki"/>
<map_variables variable_1="kss" variable_2="kss"/>
<map_variables variable_1="JdiffK" variable_2="JdiffK"/>
<map_variables variable_1="Jdiff" variable_2="Jdiff"/>
<map_variables variable_1="JdiffNa" variable_2="JdiffNa"/>
</connection>
<connection>
<map_components component_1="IpCa" component_2="membrane"/>
<map_variables variable_1="IpCa" variable_2="IpCa"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IpCa"/>
<map_variables variable_1="cai" variable_2="cai"/>
<map_variables variable_1="IpCa" variable_2="IpCa"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="ICab"/>
<map_variables variable_1="cao" variable_2="cao"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="ICab"/>
<map_variables variable_1="cai" variable_2="cai"/>
<map_variables variable_1="ICab" variable_2="ICab"/>
</connection>
<connection>
<map_components component_1="ICab" component_2="membrane"/>
<map_variables variable_1="vffrt" variable_2="vffrt"/>
<map_variables variable_1="vfrt" variable_2="vfrt"/>
<map_variables variable_1="ICab" variable_2="ICab"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="INab"/>
<map_variables variable_1="nao" variable_2="nao"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="INab"/>
<map_variables variable_1="nai" variable_2="nai"/>
<map_variables variable_1="INab" variable_2="INab"/>
</connection>
<connection>
<map_components component_1="INab" component_2="membrane"/>
<map_variables variable_1="vffrt" variable_2="vffrt"/>
<map_variables variable_1="vfrt" variable_2="vfrt"/>
<map_variables variable_1="INab" variable_2="INab"/>
</connection>
<connection>
<map_components component_1="IKb" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="IKb" variable_2="IKb"/>
</connection>
<connection>
<map_components component_1="IKb" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
</connection>
<connection>
<map_components component_1="IKb" component_2="reversal_potentials"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IKb"/>
<map_variables variable_1="IKb" variable_2="IKb"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="INaK"/>
<map_variables variable_1="ki" variable_2="ki"/>
<map_variables variable_1="nai" variable_2="nai"/>
<map_variables variable_1="INaK" variable_2="INaK"/>
</connection>
<connection>
<map_components component_1="INaK" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="INaK" variable_2="INaK"/>
</connection>
<connection>
<map_components component_1="INaK" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
</connection>
<connection>
<map_components component_1="INaK" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="zna" variable_2="zna"/>
<map_variables variable_1="zk" variable_2="zk"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="INaK"/>
<map_variables variable_1="nao" variable_2="nao"/>
<map_variables variable_1="ko" variable_2="ko"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="INaCa_i"/>
<map_variables variable_1="cai" variable_2="cai"/>
<map_variables variable_1="nai" variable_2="nai"/>
<map_variables variable_1="nass" variable_2="nass"/>
<map_variables variable_1="cass" variable_2="cass"/>
<map_variables variable_1="INaCa_i" variable_2="INaCa_i"/>
<map_variables variable_1="INaCa_ss" variable_2="INaCa_ss"/>
</connection>
<connection>
<map_components component_1="INaCa_i" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="INaCa_i" variable_2="INaCa_i"/>
<map_variables variable_1="INaCa_ss" variable_2="INaCa_ss"/>
</connection>
<connection>
<map_components component_1="INaCa_i" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
</connection>
<connection>
<map_components component_1="INaCa_i" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="zna" variable_2="zna"/>
<map_variables variable_1="zca" variable_2="zca"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="INaCa_i"/>
<map_variables variable_1="nao" variable_2="nao"/>
<map_variables variable_1="cao" variable_2="cao"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IKs"/>
<map_variables variable_1="cai" variable_2="cai"/>
<map_variables variable_1="IKs" variable_2="IKs"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="IK1" variable_2="IK1"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="IKs" variable_2="IKs"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="reversal_potentials"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="reversal_potentials"/>
<map_variables variable_1="EKs" variable_2="EKs"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="Ito" variable_2="Ito"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="INaL" variable_2="INaL"/>
</connection>
<connection>
<map_components component_1="IKr" component_2="membrane"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="IKr" variable_2="IKr"/>
</connection>
<connection>
<map_components component_1="IKr" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="reversal_potentials"/>
<map_variables variable_1="ENa" variable_2="ENa"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="reversal_potentials"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="CaMK"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="CaMK"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="INa"/>
<map_variables variable_1="tm" variable_2="tm"/>
</connection>
<connection>
<map_components component_1="INaL" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="environment"/>
<map_variables variable_1="celltype" variable_2="celltype"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="CaMK"/>
<map_variables variable_1="KmCaMK" variable_2="KmCaMK"/>
<map_variables variable_1="CaMKa" variable_2="CaMKa"/>
</connection>
<connection>
<map_components component_1="CaMK" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="ICaL"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="vffrt" variable_2="vffrt"/>
<map_variables variable_1="vfrt" variable_2="vfrt"/>
<map_variables variable_1="ICaL" variable_2="ICaL"/>
<map_variables variable_1="ICaNa" variable_2="ICaNa"/>
<map_variables variable_1="ICaK" variable_2="ICaK"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="physical_constants"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="ICaL"/>
<map_variables variable_1="cass" variable_2="cass"/>
<map_variables variable_1="nass" variable_2="nass"/>
<map_variables variable_1="kss" variable_2="kss"/>
<map_variables variable_1="ICaNa" variable_2="ICaNa"/>
<map_variables variable_1="ICaK" variable_2="ICaK"/>
<map_variables variable_1="ICaL" variable_2="ICaL"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="IK1"/>
<map_variables variable_1="ko" variable_2="ko"/>
</connection>
<connection>
<map_components component_1="intracellular_ions" component_2="IK1"/>
<map_variables variable_1="IK1" variable_2="IK1"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="ICaL"/>
<map_variables variable_1="nao" variable_2="nao"/>
<map_variables variable_1="ko" variable_2="ko"/>
<map_variables variable_1="cao" variable_2="cao"/>
</connection>
<connection>
<map_components component_1="extracellular" component_2="IKr"/>
<map_variables variable_1="ko" variable_2="ko"/>
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