Location: Andre's Hodgkin Huxley model @ 957c2190e1ee / components / INa-gating-rates.xml

Author:
David Nickerson <nickerso@users.sourceforge.net>
Date:
2015-05-25 08:31:46+12:00
Desc:
adding a SED-ML document which does nested repeated tasks to iterate over clamp potential and temperature; doesn't work with get-sed-ml-client
Permanent Source URI:
https://models.physiomeproject.org/w/andre/HH/rawfile/957c2190e1eed47d7634613250bc274dc836b826/components/INa-gating-rates.xml

<?xml version="1.0" encoding="iso-8859-1"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink" name="INa_gating_rates" cmeta:id="INa_gating_rates_model">
  
  <import xlink:href="units.xml">
    <units name="K" units_ref="K"/>
    <units name="ms" units_ref="ms"/>
    <units name="mV" units_ref="mV"/>
    <units name="per_ms" units_ref="per_ms"/>
    <units name="per_ms_mV" units_ref="per_ms_mV"/>
    <units name="uA_per_cmsq" units_ref="uA_per_cmsq"/>
    <units name="mS_per_cmsq" units_ref="mS_per_cmsq"/>
  </import>
  <component name="alpha_m" cmeta:id="alpha_m_component">
    
    <variable cmeta:id="alpha_m" name="alpha" public_interface="out" private_interface="out" units="per_ms"/>
    <variable cmeta:id="alpha_m_base" name="alpha_base" public_interface="out" private_interface="out" units="per_ms"/>
    <variable cmeta:id="alpha_m_Q10" name="Q10" public_interface="in" private_interface="out" units="dimensionless"/>
    <variable cmeta:id="alpha_m_T" name="T" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="alpha_m_Tref" name="Tref" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="alpha_m_V" name="V" public_interface="in" private_interface="out" units="mV"/>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="alpha_m_base_calculation"><eq/>
        <ci>alpha_base</ci>
        <apply><divide/>
          <apply><times/>
            <cn cellml:units="per_ms_mV">0.1</cn>
            <apply><plus/>
              <ci>V</ci>
              <cn cellml:units="mV">25.0</cn>
            </apply>
          </apply>
          <apply><minus/>
            <apply><exp/>
              <apply><divide/>
                <apply><plus/>
                  <ci>V</ci>
                  <cn cellml:units="mV">25.0</cn>
                </apply>
                <cn cellml:units="mV">10.0</cn>
              </apply>
            </apply>
            <cn cellml:units="dimensionless">1.0</cn>
          </apply>
        </apply>
      </apply>
    </math>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="alpha_m_calculation"><eq/>
        <ci>alpha</ci>
        <apply><times/>
          <apply><power/>
            <ci>Q10</ci>
            <apply><divide/>
              <apply><minus/>
                <ci>T</ci>
                <ci>Tref</ci>
              </apply>
              <cn cellml:units="K">10.0</cn>
            </apply>
          </apply>
          <ci>alpha_base</ci>
        </apply>
      </apply>
    </math>
  </component>
  <component name="beta_m" cmeta:id="beta_m_component">
    
    <variable cmeta:id="beta_m" name="beta" public_interface="out" private_interface="out" units="per_ms"/>
    <variable cmeta:id="beta_m_base" name="beta_base" public_interface="out" private_interface="out" units="per_ms"/>
    <variable cmeta:id="beta_m_Q10" name="Q10" public_interface="in" private_interface="out" units="dimensionless"/>
    <variable cmeta:id="beta_m_T" name="T" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="beta_m_Tref" name="Tref" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="beta_m_V" name="V" public_interface="in" private_interface="out" units="mV"/>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="beta_m_base_calculation"><eq/>
        <ci>beta_base</ci>
        <apply><times/>
          <cn cellml:units="per_ms">4.0</cn>
          <apply><exp/>
            <apply><divide/>
              <ci>V</ci>
              <cn cellml:units="mV">18.0</cn>
            </apply>
          </apply>
        </apply>
      </apply>
    </math>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="beta_m_calculation"><eq/>
        <ci>beta</ci>
        <apply><times/>
          <apply><power/>
            <ci>Q10</ci>
            <apply><divide/>
              <apply><minus/>
                <ci>T</ci>
                <ci>Tref</ci>
              </apply>
              <cn cellml:units="K">10.0</cn>
            </apply>
          </apply>
          <ci>beta_base</ci>
        </apply>
      </apply>
    </math>
  </component>
  <component name="alpha_h" cmeta:id="alpha_h_component">
    
    <variable cmeta:id="alpha_h" name="alpha" public_interface="out" private_interface="out" units="per_ms"/>
    <variable cmeta:id="alpha_h_base" name="alpha_base" public_interface="out" private_interface="out" units="per_ms"/>
    <variable cmeta:id="alpha_h_Q10" name="Q10" public_interface="in" private_interface="out" units="dimensionless"/>
    <variable cmeta:id="alpha_h_T" name="T" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="alpha_h_Tref" name="Tref" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="alpha_h_V" name="V" public_interface="in" private_interface="out" units="mV"/>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="alpha_h_base_calculation"><eq/>
        <ci>alpha_base</ci>
        <apply><times/>
          <cn cellml:units="per_ms">0.07</cn>
          <apply><exp/>
            <apply><divide/>
              <ci>V</ci>
              <cn cellml:units="mV">20.0</cn>
            </apply>
          </apply>
        </apply>
      </apply>
    </math>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="alpha_h_calculation"><eq/>
        <ci>alpha</ci>
        <apply><times/>
          <apply><power/>
            <ci>Q10</ci>
            <apply><divide/>
              <apply><minus/>
                <ci>T</ci>
                <ci>Tref</ci>
              </apply>
              <cn cellml:units="K">10.0</cn>
            </apply>
          </apply>
          <ci>alpha_base</ci>
        </apply>
      </apply>
    </math>
  </component>
  <component name="beta_h" cmeta:id="beta_h_component">
    
    <variable cmeta:id="beta_h" name="beta" public_interface="out" private_interface="out" units="per_ms"/>
    <variable cmeta:id="beta_h_base" name="beta_base" public_interface="out" private_interface="out" units="per_ms"/>
    <variable cmeta:id="beta_h_Q10" name="Q10" public_interface="in" private_interface="out" units="dimensionless"/>
    <variable cmeta:id="beta_h_T" name="T" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="beta_h_Tref" name="Tref" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="beta_h_V" name="V" public_interface="in" private_interface="out" units="mV"/>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="beta_h_base_calculation"><eq/>
        <ci>beta_base</ci>
        <apply><divide/>
          <cn cellml:units="per_ms">1.0</cn>
          <apply><plus/>
            <apply><exp/>
              <apply><divide/>
                <apply><plus/>
                  <ci>V</ci>
                  <cn cellml:units="mV">30.0</cn>
                </apply>
                <cn cellml:units="mV">10.0</cn>
              </apply>
            </apply>
            <cn cellml:units="dimensionless">1.0</cn>
          </apply>
        </apply>
      </apply>
    </math>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="beta_h_calculation"><eq/>
        <ci>beta</ci>
        <apply><times/>
          <apply><power/>
            <ci>Q10</ci>
            <apply><divide/>
              <apply><minus/>
                <ci>T</ci>
                <ci>Tref</ci>
              </apply>
              <cn cellml:units="K">10.0</cn>
            </apply>
          </apply>
          <ci>beta_base</ci>
        </apply>
      </apply>
    </math>
  </component>
</model>