Location: Andre's Hodgkin Huxley model @ 957c2190e1ee / components / IK.xml

Author:
David Nickerson <nickerso@users.sourceforge.net>
Date:
2015-05-25 08:31:46+12:00
Desc:
adding a SED-ML document which does nested repeated tasks to iterate over clamp potential and temperature; doesn't work with get-sed-ml-client
Permanent Source URI:
https://models.physiomeproject.org/w/andre/HH/rawfile/957c2190e1eed47d7634613250bc274dc836b826/components/IK.xml

<?xml version="1.0" encoding="iso-8859-1"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink" name="IK" cmeta:id="IK_model">
  
  <import xlink:href="units.xml">
    <units name="K" units_ref="K"/>
    <units name="ms" units_ref="ms"/>
    <units name="mV" units_ref="mV"/>
    <units name="per_ms" units_ref="per_ms"/>
    <units name="per_ms_mV" units_ref="per_ms_mV"/>
    <units name="uA_per_cmsq" units_ref="uA_per_cmsq"/>
    <units name="mS_per_cmsq" units_ref="mS_per_cmsq"/>
  </import>
  <import xlink:href="gating-variable.xml">
    <component name="n_gate" component_ref="hh_gating_variable_dynamic"/>
  </import>
  <import xlink:href="IK-gating-rates.xml">
    <component cmeta:id="alpha_n_component" name="alpha_n" component_ref="alpha_n"/>
    <component cmeta:id="beta_n_component" name="beta_n" component_ref="beta_n"/>
  </import>
  <component name="IK" cmeta:id="IK_component">
    
    <variable cmeta:id="IK" name="IK" public_interface="out" private_interface="out" units="uA_per_cmsq"/>
    <variable cmeta:id="n_initial" name="n_initial" public_interface="in" private_interface="out" units="dimensionless"/>
    <variable cmeta:id="n" name="n" public_interface="out" private_interface="in" units="dimensionless"/>
    <variable cmeta:id="time" name="time" public_interface="in" private_interface="out" units="ms"/>
    <variable cmeta:id="Tref" name="Tref" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="T" name="T" public_interface="in" private_interface="out" units="K"/>
    <variable cmeta:id="Q10" name="Q10" public_interface="in" private_interface="out" units="dimensionless"/>
    <variable cmeta:id="V" name="V" public_interface="in" private_interface="out" units="mV"/>
    <variable cmeta:id="VK" name="VK" public_interface="in" private_interface="out" units="mV"/>
    <variable cmeta:id="gK" name="gK" public_interface="out" private_interface="out" units="mS_per_cmsq"/>
    <variable cmeta:id="gK_max" name="gK_max" public_interface="in" private_interface="out" units="mS_per_cmsq"/>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="IK_calculation"><eq/>
        <ci>IK</ci>
        <apply><times/>
          <ci>gK</ci>
          <apply><minus/>
            <ci>V</ci>
            <ci>VK</ci>
          </apply>
        </apply>
      </apply>
    </math>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="gK_calculation"><eq/>
        <ci>gK</ci>
        <apply><times/>
          <ci>gK_max</ci>
          <apply><power/>
            <ci>n</ci>
            <cn cellml:units="dimensionless">4.0</cn>
          </apply>
        </apply>
      </apply>
    </math>
  </component>
  <group>
    <relationship_ref relationship="encapsulation"/>
    <component_ref component="IK">
      <component_ref component="alpha_n"/>
      <component_ref component="beta_n"/>
      <component_ref component="n_gate"/>
    </component_ref>
  </group>
  <connection>
    <map_components component_1="IK" component_2="n_gate"/>
    <map_variables variable_1="time" variable_2="time"/>
    <map_variables variable_1="n_initial" variable_2="gate_initial"/>
    <map_variables variable_1="n" variable_2="gate"/>
  </connection>
  <connection>
    <map_components component_1="IK" component_2="alpha_n"/>
    <map_variables variable_1="Q10" variable_2="Q10"/>
    <map_variables variable_1="T" variable_2="T"/>
    <map_variables variable_1="Tref" variable_2="Tref"/>
    <map_variables variable_1="V" variable_2="V"/>
  </connection>
  <connection>
    <map_components component_1="IK" component_2="beta_n"/>
    <map_variables variable_1="Q10" variable_2="Q10"/>
    <map_variables variable_1="T" variable_2="T"/>
    <map_variables variable_1="Tref" variable_2="Tref"/>
    <map_variables variable_1="V" variable_2="V"/>
  </connection>
  <connection>
    <map_components component_1="n_gate" component_2="alpha_n"/>
    <map_variables variable_1="alpha" variable_2="alpha"/>
  </connection>
  <connection>
    <map_components component_1="n_gate" component_2="beta_n"/>
    <map_variables variable_1="beta" variable_2="beta"/>
  </connection>
</model>