function [VOI, STATES, ALGEBRAIC, CONSTANTS] = mainFunction()
    % This is the "main function".  In Matlab, things work best if you rename this function to match the filename.
   [VOI, STATES, ALGEBRAIC, CONSTANTS] = solveModel();
end

function [algebraicVariableCount] = getAlgebraicVariableCount() 
    % Used later when setting a global variable with the number of algebraic variables.
    % Note: This is not the "main method".  
    algebraicVariableCount =10;
end
% There are a total of 4 entries in each of the rate and state variable arrays.
% There are a total of 21 entries in the constant variable array.
%

function [VOI, STATES, ALGEBRAIC, CONSTANTS] = solveModel()
    % Create ALGEBRAIC of correct size
    global algebraicVariableCount;  algebraicVariableCount = getAlgebraicVariableCount();
    % Initialise constants and state variables
    [INIT_STATES, CONSTANTS] = initConsts;

    % Set timespan to solve over 
    tspan = [0, 10];

    % Set numerical accuracy options for ODE solver
    options = odeset('RelTol', 1e-06, 'AbsTol', 1e-06, 'MaxStep', 1);

    % Solve model with ODE solver
    [VOI, STATES] = ode15s(@(VOI, STATES)computeRates(VOI, STATES, CONSTANTS), tspan, INIT_STATES, options);

    % Compute algebraic variables
    [RATES, ALGEBRAIC] = computeRates(VOI, STATES, CONSTANTS);
    ALGEBRAIC = computeAlgebraic(ALGEBRAIC, CONSTANTS, STATES, VOI);

    % Plot state variables against variable of integration
    [LEGEND_STATES, LEGEND_ALGEBRAIC, LEGEND_VOI, LEGEND_CONSTANTS] = createLegends();
    figure();
    plot(VOI, STATES);
    xlabel(LEGEND_VOI);
    l = legend(LEGEND_STATES);
    set(l,'Interpreter','none');
end

function [LEGEND_STATES, LEGEND_ALGEBRAIC, LEGEND_VOI, LEGEND_CONSTANTS] = createLegends()
    LEGEND_STATES = ''; LEGEND_ALGEBRAIC = ''; LEGEND_VOI = ''; LEGEND_CONSTANTS = '';
    LEGEND_VOI = strpad('time in component environment (millisecond)');
    LEGEND_CONSTANTS(:,1) = strpad('Cm in component membrane (femtoF)');
    LEGEND_STATES(:,1) = strpad('V in component membrane (millivolt)');
    LEGEND_ALGEBRAIC(:,5) = strpad('ICa in component Ca_current (femtoA)');
    LEGEND_ALGEBRAIC(:,7) = strpad('IK in component rapid_K_current (femtoA)');
    LEGEND_ALGEBRAIC(:,10) = strpad('Il in component leak_current (femtoA)');
    LEGEND_ALGEBRAIC(:,8) = strpad('Is1 in component slow_K_current (femtoA)');
    LEGEND_ALGEBRAIC(:,9) = strpad('Is2 in component very_slow_K_current (femtoA)');
    LEGEND_CONSTANTS(:,2) = strpad('Vm in component Ca_current (millivolt)');
    LEGEND_CONSTANTS(:,3) = strpad('VCa in component Ca_current (millivolt)');
    LEGEND_CONSTANTS(:,4) = strpad('gCa in component Ca_current (picoS)');
    LEGEND_ALGEBRAIC(:,1) = strpad('minf in component Ca_current (dimensionless)');
    LEGEND_CONSTANTS(:,5) = strpad('sm in component Ca_current (millivolt)');
    LEGEND_CONSTANTS(:,6) = strpad('VK in component rapid_K_current (millivolt)');
    LEGEND_CONSTANTS(:,7) = strpad('gK in component rapid_K_current (picoS)');
    LEGEND_STATES(:,2) = strpad('n in component rapid_K_current (dimensionless)');
    LEGEND_CONSTANTS(:,8) = strpad('lambda in component rapid_K_current (dimensionless)');
    LEGEND_CONSTANTS(:,9) = strpad('tnbar in component rapid_K_current (dimensionless)');
    LEGEND_CONSTANTS(:,10) = strpad('Vn in component rapid_K_current (millivolt)');
    LEGEND_CONSTANTS(:,11) = strpad('sn in component rapid_K_current (millivolt)');
    LEGEND_ALGEBRAIC(:,6) = strpad('taun in component rapid_K_current (dimensionless)');
    LEGEND_ALGEBRAIC(:,2) = strpad('ninf in component rapid_K_current (dimensionless)');
    LEGEND_CONSTANTS(:,12) = strpad('gs1 in component slow_K_current (picoS)');
    LEGEND_STATES(:,3) = strpad('s1 in component slow_K_current (dimensionless)');
    LEGEND_ALGEBRAIC(:,3) = strpad('s1inf in component slow_K_current (dimensionless)');
    LEGEND_CONSTANTS(:,13) = strpad('Vs1 in component slow_K_current (millivolt)');
    LEGEND_CONSTANTS(:,14) = strpad('ss1 in component slow_K_current (millivolt)');
    LEGEND_CONSTANTS(:,15) = strpad('taus1 in component slow_K_current (dimensionless)');
    LEGEND_CONSTANTS(:,16) = strpad('Vs2 in component very_slow_K_current (millivolt)');
    LEGEND_STATES(:,4) = strpad('s2 in component very_slow_K_current (dimensionless)');
    LEGEND_ALGEBRAIC(:,4) = strpad('s2inf in component very_slow_K_current (dimensionless)');
    LEGEND_CONSTANTS(:,17) = strpad('ss2 in component very_slow_K_current (millivolt)');
    LEGEND_CONSTANTS(:,18) = strpad('gs2 in component very_slow_K_current (picoS)');
    LEGEND_CONSTANTS(:,19) = strpad('taus2 in component very_slow_K_current (dimensionless)');
    LEGEND_CONSTANTS(:,20) = strpad('gl in component leak_current (picoS)');
    LEGEND_CONSTANTS(:,21) = strpad('Vl in component leak_current (millivolt)');
    LEGEND_RATES(:,1) = strpad('d/dt V in component membrane (millivolt)');
    LEGEND_RATES(:,2) = strpad('d/dt n in component rapid_K_current (dimensionless)');
    LEGEND_RATES(:,3) = strpad('d/dt s1 in component slow_K_current (dimensionless)');
    LEGEND_RATES(:,4) = strpad('d/dt s2 in component very_slow_K_current (dimensionless)');
    LEGEND_STATES  = LEGEND_STATES';
    LEGEND_ALGEBRAIC = LEGEND_ALGEBRAIC';
    LEGEND_RATES = LEGEND_RATES';
    LEGEND_CONSTANTS = LEGEND_CONSTANTS';
end

function [STATES, CONSTANTS] = initConsts()
    VOI = 0; CONSTANTS = []; STATES = []; ALGEBRAIC = [];
    CONSTANTS(:,1) = 4524;
    STATES(:,1) = -43;
    CONSTANTS(:,2) = -22;
    CONSTANTS(:,3) = 100;
    CONSTANTS(:,4) = 280;
    CONSTANTS(:,5) = 7.5;
    CONSTANTS(:,6) = -80;
    CONSTANTS(:,7) = 1300;
    STATES(:,2) = 0.03;
    CONSTANTS(:,8) = 1.1;
    CONSTANTS(:,9) = 9.09;
    CONSTANTS(:,10) = -9;
    CONSTANTS(:,11) = 10;
    CONSTANTS(:,12) = 20;
    STATES(:,3) = 0.1;
    CONSTANTS(:,13) = -40;
    CONSTANTS(:,14) = 0.5;
    CONSTANTS(:,15) = 1000;
    CONSTANTS(:,16) = -42;
    STATES(:,4) = 0.434;
    CONSTANTS(:,17) = 0.4;
    CONSTANTS(:,18) = 32;
    CONSTANTS(:,19) = 120000;
    CONSTANTS(:,20) = 25;
    CONSTANTS(:,21) = -40;
    if (isempty(STATES)), warning('Initial values for states not set');, end
end

function [RATES, ALGEBRAIC] = computeRates(VOI, STATES, CONSTANTS)
    global algebraicVariableCount;
    statesSize = size(STATES);
    statesColumnCount = statesSize(2);
    if ( statesColumnCount == 1)
        STATES = STATES';
        ALGEBRAIC = zeros(1, algebraicVariableCount);
        utilOnes = 1;
    else
        statesRowCount = statesSize(1);
        ALGEBRAIC = zeros(statesRowCount, algebraicVariableCount);
        RATES = zeros(statesRowCount, statesColumnCount);
        utilOnes = ones(statesRowCount, 1);
    end
    ALGEBRAIC(:,3) = 1.00000./(1.00000+exp((CONSTANTS(:,13) - STATES(:,1))./CONSTANTS(:,14)));
    RATES(:,3) = (ALGEBRAIC(:,3) - STATES(:,3))./( CONSTANTS(:,15).*1.00000);
    ALGEBRAIC(:,4) = 1.00000./(1.00000+exp((CONSTANTS(:,16) - STATES(:,1))./CONSTANTS(:,17)));
    RATES(:,4) = (ALGEBRAIC(:,4) - STATES(:,4))./( CONSTANTS(:,19).*1.00000);
    ALGEBRAIC(:,6) = CONSTANTS(:,9)./(1.00000+exp((STATES(:,1) - CONSTANTS(:,10))./CONSTANTS(:,11)));
    ALGEBRAIC(:,2) = 1.00000./(1.00000+exp((CONSTANTS(:,10) - STATES(:,1))./CONSTANTS(:,11)));
    RATES(:,2) = ( CONSTANTS(:,8).*(ALGEBRAIC(:,2) - STATES(:,2)))./( ALGEBRAIC(:,6).*1.00000);
    ALGEBRAIC(:,1) = 1.00000./(1.00000+exp((CONSTANTS(:,2) - STATES(:,1))./CONSTANTS(:,5)));
    ALGEBRAIC(:,5) =  CONSTANTS(:,4).*ALGEBRAIC(:,1).*(STATES(:,1) - CONSTANTS(:,3));
    ALGEBRAIC(:,7) =  CONSTANTS(:,7).*STATES(:,2).*(STATES(:,1) - CONSTANTS(:,6));
    ALGEBRAIC(:,10) =  CONSTANTS(:,20).*(STATES(:,1) - CONSTANTS(:,21));
    ALGEBRAIC(:,8) =  CONSTANTS(:,12).*STATES(:,3).*(STATES(:,1) - CONSTANTS(:,6));
    ALGEBRAIC(:,9) =  CONSTANTS(:,18).*STATES(:,4).*(STATES(:,1) - CONSTANTS(:,6));
    RATES(:,1) =  - (ALGEBRAIC(:,5)+ALGEBRAIC(:,7)+ALGEBRAIC(:,10)+ALGEBRAIC(:,8)+ALGEBRAIC(:,9))./CONSTANTS(:,1);
   RATES = RATES';
end

% Calculate algebraic variables
function ALGEBRAIC = computeAlgebraic(ALGEBRAIC, CONSTANTS, STATES, VOI)
    statesSize = size(STATES);
    statesColumnCount = statesSize(2);
    if ( statesColumnCount == 1)
        STATES = STATES';
        utilOnes = 1;
    else
        statesRowCount = statesSize(1);
        utilOnes = ones(statesRowCount, 1);
    end
    ALGEBRAIC(:,3) = 1.00000./(1.00000+exp((CONSTANTS(:,13) - STATES(:,1))./CONSTANTS(:,14)));
    ALGEBRAIC(:,4) = 1.00000./(1.00000+exp((CONSTANTS(:,16) - STATES(:,1))./CONSTANTS(:,17)));
    ALGEBRAIC(:,6) = CONSTANTS(:,9)./(1.00000+exp((STATES(:,1) - CONSTANTS(:,10))./CONSTANTS(:,11)));
    ALGEBRAIC(:,2) = 1.00000./(1.00000+exp((CONSTANTS(:,10) - STATES(:,1))./CONSTANTS(:,11)));
    ALGEBRAIC(:,1) = 1.00000./(1.00000+exp((CONSTANTS(:,2) - STATES(:,1))./CONSTANTS(:,5)));
    ALGEBRAIC(:,5) =  CONSTANTS(:,4).*ALGEBRAIC(:,1).*(STATES(:,1) - CONSTANTS(:,3));
    ALGEBRAIC(:,7) =  CONSTANTS(:,7).*STATES(:,2).*(STATES(:,1) - CONSTANTS(:,6));
    ALGEBRAIC(:,10) =  CONSTANTS(:,20).*(STATES(:,1) - CONSTANTS(:,21));
    ALGEBRAIC(:,8) =  CONSTANTS(:,12).*STATES(:,3).*(STATES(:,1) - CONSTANTS(:,6));
    ALGEBRAIC(:,9) =  CONSTANTS(:,18).*STATES(:,4).*(STATES(:,1) - CONSTANTS(:,6));
end

% Pad out or shorten strings to a set length
function strout = strpad(strin)
    req_length = 160;
    insize = size(strin,2);
    if insize > req_length
        strout = strin(1:req_length);
    else
        strout = [strin, blanks(req_length - insize)];
    end
end