HH11, HH12, HH13, and HH14:
Calculation of a multiplier factor that decreases cardiac pumping effectiveness (HMD)
when the cellular P02 of the heart muscle cells (POT) falls too low. The sensitivity
control is DHDTR, and the effect is limited by Block HH14 so that no change in HMD
occurs until the cell PO2 falls below the input value to the side of Block HH11.
Description of Guyton heart hypertrophy or deterioration module
2008-00-00 00:00
Heart Hypertrophy or Deterioration
Guyton
keyword
HH11, HH12, HH13, and HH14:
Calculation of a multiplier factor that decreases cardiac pumping effectiveness (HMD)
when the cellular P02 of the heart muscle cells (POT) falls too low. The sensitivity
control is DHDTR, and the effect is limited by Block HH14 so that no change in HMD
occurs until the cell PO2 falls below the input value to the side of Block HH11.
HH11, HH12, HH13, and HH14:
Calculation of a multiplier factor that decreases cardiac pumping effectiveness (HMD)
when the cellular P02 of the heart muscle cells (POT) falls too low. The sensitivity
control is DHDTR, and the effect is limited by Block HH14 so that no change in HMD
occurs until the cell PO2 falls below the input value to the side of Block HH11.
HH1A, HH1, and HH2:
Calculation of a quantitative value (output of Block HH2) which is a multiplier
that is approached asymptotically in response to three factors that cause left
ventricular hypertrophy, (1) the arterial pressure (PA), (2) the cardiac output (QAO),
and (3) the basic strength of the heart (HSL). The degree of hypertrophy in response
to the input factors is controlled by the exponent (Z13) in Block HH2.
HH3, HH4, and HH5:
Calculation of the actual degree of hypertrophy of the left ventricle (HPL) that
results over a period of time in response to arterial pressure (PA), cardiac output (QAO),
and basic left ventricular strength (HSL). The value HPL approaches the output value
from Block HH2 asymptotically with a time constant equal to the input variable at the
side of Block HH4.
physiology
cardiovascular circulation
heart hypertrophy or deterioration
organ systems
Guyton
HH6A, HH6, HH7, HH8, HH9, and HH10:
Calculation of the degree of hypertrophy of the right ventricle (HPR) according
to the same scheme as noted above for left ventricular hypertrophy, but with different
inputs: pulmonary arterial pressure (PPA), cardiac output (QAO), and basic normal
strength of the right heart (HSR).
Effect of heart hypertrophy or heart deterioration on heart pumping capability.
HH6A, HH6, HH7, HH8, HH9, and HH10:
Calculation of the degree of hypertrophy of the right ventricle (HPR) according
to the same scheme as noted above for left ventricular hypertrophy, but with different
inputs: pulmonary arterial pressure (PPA), cardiac output (QAO), and basic normal
strength of the right heart (HSR).
500000
HH1A, HH1, and HH2:
Calculation of a quantitative value (output of Block HH2) which is a multiplier
that is approached asymptotically in response to three factors that cause left
ventricular hypertrophy, (1) the arterial pressure (PA), (2) the cardiac output (QAO),
and (3) the basic strength of the heart (HSL). The degree of hypertrophy in response
to the input factors is controlled by the exponent (Z13) in Block HH2.
HH3, HH4, and HH5:
Calculation of the actual degree of hypertrophy of the left ventricle (HPL) that
results over a period of time in response to arterial pressure (PA), cardiac output (QAO),
and basic left ventricular strength (HSL). The value HPL approaches the output value
from Block HH2 asymptotically with a time constant equal to the input variable at the
side of Block HH4.
100000
500000
Encapsulation grouping component containing all the components in the Heart Hypertrophy or Deterioration Model.
The inputs and outputs of the Model must be passed by this component.
100000
HH11, HH12, HH13, and HH14:
Calculation of a multiplier factor that decreases cardiac pumping effectiveness (HMD)
when the cellular P02 of the heart muscle cells (POT) falls too low. The sensitivity
control is DHDTR, and the effect is limited by Block HH14 so that no change in HMD
occurs until the cell PO2 falls below the input value to the side of Block HH11.