W
Chandler
D
Altered documentation such that the semicolons are now with the correct comments in the list.
A stimulus protocol (with the same parameters as the Beeler Reuter 97, as the required parameters are unknown) has been added to this model to allow simulation of action potentials.
L
A
Hodgkin
The leak current component contains the differential equations
governing the time independent current leakage from the cell.
Mammalia
Skeletal Myocyte
The Adrian-Chandler-Hodgkin Model of the Skeletal Myocyte Action
Potential, 1970
100000
bdf15
0.001
10000
This is the CellML description of Adrian, Chandler and Hodgkin's mathematical model of membrane action potentials of mammalian striated skeletal muscle. It describes four ionic currents and uses Hodgkin-Huxley type equations.
L
D
Peachey
H
R
Adrian
This component contains the differential equations
governing the time dependence of the n gate of the potassium channel.
2009-05-05T11:14:24+12:00
2003-10-29T00:00:00+00:00
Martin Buist
James
Lawson
Richard
2007-06-11T13:17:56+12:00
Bioengineering Institute, The University of Auckland
The T-tubular current component contains the differential equations
governing the current that occurs as the result of a potential difference
between the cell membrane and the T-tubular system.
skeletal muscle
cardiac
myofilament mechanics
electrophysiology
May
Lloyd
Catherine
2007-11-12T12:20:00+13:00
This component defines the calculation of dV/dt, the ordinary differential
equation for the transmembrane potential.
H
R
Adrian
1973-01-01
Voltage clamp experiments in striated muscle fibres
607
208
644
Richard
Lawson
James
Reconstruction of the action potential of frog sartorius muscle
103
235
131
The sodium current component contains the differential equations
governing the influx of sodium ions through the cell surface
membrane into the cell.
Buist
Martin
L
The definition of the voltage-dependent activation gating
kinetics for the sodium ion channel (the m gate).
The T-tubular Vt component calculates the voltage in the membrane
of the T-tubular system.
keyword
5499787
1970-01-01
m.buist@auckland.ac.nz
The University of Auckland
Bioengineering Institute
Journal of Physiology
James Lawson
Journal of Physiology
The voltage-dependent inactivation gate for the sodium channel (the
h gate).
This model has had a stimulus protocol added to it to allow simulation of action potentials. Unfortunately, the details of the stimulation defined in the original paper are not known and as such, the parameters of the stimulus (magnitude, duration, dimensions,) may not be appropriate. Currently, however, the model runs in PCEnv 0.2 and is able to simulate a train of action potentials. COR will not currently run this model.
4778131
Updated curation status
This component defines the variables that are externally set and
passed into the model along with the variables within the model that
are to be available externally.
The potassium current component contains the differential equations
governing this voltage and time dependent outward current.