Generated Code
The following is c code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 62 entries in the algebraic variable array.
There are a total of 25 entries in each of the rate and state variable arrays.
There are a total of 92 entries in the constant variable array.
*/
/*
* VOI is time in component environment (second).
* STATES[0] is V in component membrane (millivolt).
* CONSTANTS[0] is R in component membrane (joule_per_kilomole_kelvin).
* CONSTANTS[1] is T in component membrane (kelvin).
* CONSTANTS[2] is F in component membrane (coulomb_per_mole).
* CONSTANTS[3] is Cm in component membrane (microF).
* ALGEBRAIC[35] is i_K1 in component time_independent_potassium_current (nanoA).
* ALGEBRAIC[52] is i_to in component transient_outward_current (nanoA).
* ALGEBRAIC[37] is i_Kr in component rapid_delayed_rectifier_potassium_current (nanoA).
* ALGEBRAIC[39] is i_Ks in component slow_delayed_rectifier_potassium_current (nanoA).
* ALGEBRAIC[40] is i_K_ATP in component ATP_dependent_potassium_current (nanoA).
* ALGEBRAIC[53] is i_K_ACh in component ACh_dependent_potassium_current (nanoA).
* ALGEBRAIC[45] is i_Ca_L_K_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[48] is i_Ca_L_K_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[54] is i_NaK in component sodium_potassium_pump (nanoA).
* ALGEBRAIC[41] is i_Na in component fast_sodium_current (nanoA).
* ALGEBRAIC[43] is i_b_Na in component sodium_background_current (nanoA).
* ALGEBRAIC[42] is i_p_Na in component persistent_sodium_current (nanoA).
* ALGEBRAIC[46] is i_Ca_L_Na_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[49] is i_Ca_L_Na_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[55] is i_NaCa_cyt in component sodium_calcium_exchanger (nanoA).
* ALGEBRAIC[56] is i_NaCa_ds in component sodium_calcium_exchanger (nanoA).
* ALGEBRAIC[44] is i_Ca_L_Ca_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[47] is i_Ca_L_Ca_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[51] is i_b_Ca in component calcium_background_current (nanoA).
* ALGEBRAIC[8] is i_Stim in component membrane (nanoA).
* CONSTANTS[4] is stim_start in component membrane (second).
* CONSTANTS[5] is stim_end in component membrane (second).
* CONSTANTS[6] is stim_period in component membrane (second).
* CONSTANTS[7] is stim_duration in component membrane (second).
* CONSTANTS[8] is stim_amplitude in component membrane (nanoA).
* ALGEBRAIC[20] is E_Na in component reversal_potentials (millivolt).
* ALGEBRAIC[26] is E_K in component reversal_potentials (millivolt).
* ALGEBRAIC[29] is E_Ks in component reversal_potentials (millivolt).
* ALGEBRAIC[31] is E_Ca in component reversal_potentials (millivolt).
* ALGEBRAIC[33] is E_mh in component reversal_potentials (millivolt).
* CONSTANTS[9] is P_kna in component reversal_potentials (dimensionless).
* CONSTANTS[10] is K_o in component extracellular_potassium_concentration (millimolar).
* CONSTANTS[11] is Na_o in component extracellular_sodium_concentration (millimolar).
* STATES[1] is K_i in component intracellular_potassium_concentration (millimolar).
* STATES[2] is Na_i in component intracellular_sodium_concentration (millimolar).
* CONSTANTS[12] is Ca_o in component extracellular_calcium_concentration (millimolar).
* STATES[3] is Ca_i in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[13] is K_mk1 in component time_independent_potassium_current (millimolar).
* CONSTANTS[14] is g_K1 in component time_independent_potassium_current (microS).
* CONSTANTS[15] is shiftK1 in component time_independent_potassium_current (millivolt).
* CONSTANTS[16] is steepK1 in component time_independent_potassium_current (dimensionless).
* CONSTANTS[17] is g_Kr1 in component rapid_delayed_rectifier_potassium_current (microS).
* CONSTANTS[18] is g_Kr2 in component rapid_delayed_rectifier_potassium_current (microS).
* STATES[4] is xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (dimensionless).
* STATES[5] is xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (dimensionless).
* ALGEBRAIC[0] is alpha_xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (per_second).
* ALGEBRAIC[12] is beta_xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (per_second).
* ALGEBRAIC[1] is alpha_xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (per_second).
* ALGEBRAIC[13] is beta_xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (per_second).
* CONSTANTS[19] is g_Ks in component slow_delayed_rectifier_potassium_current (microS).
* STATES[6] is xs in component slow_delayed_rectifier_potassium_current_xs_gate (dimensionless).
* ALGEBRAIC[2] is alpha_xs in component slow_delayed_rectifier_potassium_current_xs_gate (per_second).
* ALGEBRAIC[14] is beta_xs in component slow_delayed_rectifier_potassium_current_xs_gate (per_second).
* CONSTANTS[20] is g_K_ATP in component ATP_dependent_potassium_current (microS).
* CONSTANTS[21] is K_ATP in component ATP_dependent_potassium_current (millimolar).
* CONSTANTS[22] is ATP in component ATP_dependent_potassium_current (millimolar).
* ALGEBRAIC[28] is i_KNa in component sodium_activated_potassium_current (nanoA).
* CONSTANTS[23] is g_K_Na in component sodium_activated_potassium_current (microS).
* CONSTANTS[24] is K_kna in component sodium_activated_potassium_current (millimolar).
* CONSTANTS[25] is g_Na in component fast_sodium_current (microS).
* STATES[7] is m in component fast_sodium_current_m_gate (dimensionless).
* STATES[8] is h in component fast_sodium_current_h_gate (dimensionless).
* ALGEBRAIC[15] is alpha_m in component fast_sodium_current_m_gate (per_second).
* ALGEBRAIC[23] is beta_m in component fast_sodium_current_m_gate (per_second).
* CONSTANTS[26] is delta_m in component fast_sodium_current_m_gate (millivolt).
* ALGEBRAIC[3] is E0_m in component fast_sodium_current_m_gate (millivolt).
* ALGEBRAIC[4] is alpha_h in component fast_sodium_current_h_gate (per_second).
* ALGEBRAIC[16] is beta_h in component fast_sodium_current_h_gate (per_second).
* CONSTANTS[27] is shift_h in component fast_sodium_current_h_gate (millivolt).
* CONSTANTS[28] is g_pna in component persistent_sodium_current (microS).
* CONSTANTS[29] is g_bna in component sodium_background_current (microS).
* ALGEBRAIC[50] is i_Ca_L in component L_type_Ca_channel (nanoA).
* CONSTANTS[30] is P_Ca_L in component L_type_Ca_channel (nanoA_per_millimolar).
* CONSTANTS[31] is P_CaK in component L_type_Ca_channel (dimensionless).
* CONSTANTS[32] is P_CaNa in component L_type_Ca_channel (dimensionless).
* STATES[9] is Ca_ds in component intracellular_calcium_concentration (millimolar).
* STATES[10] is d in component L_type_Ca_channel_d_gate (dimensionless).
* STATES[11] is f in component L_type_Ca_channel_f_gate (dimensionless).
* STATES[12] is f2 in component L_type_Ca_channel_f2_gate (dimensionless).
* STATES[13] is f2ds in component L_type_Ca_channel_f2ds_gate (dimensionless).
* CONSTANTS[33] is Km_f2 in component L_type_Ca_channel (millimolar).
* CONSTANTS[34] is Km_f2ds in component L_type_Ca_channel (millimolar).
* CONSTANTS[35] is R_decay in component L_type_Ca_channel (per_second).
* CONSTANTS[36] is FrICa in component L_type_Ca_channel (dimensionless).
* ALGEBRAIC[17] is alpha_d in component L_type_Ca_channel_d_gate (per_second).
* ALGEBRAIC[24] is beta_d in component L_type_Ca_channel_d_gate (per_second).
* ALGEBRAIC[5] is E0_d in component L_type_Ca_channel_d_gate (millivolt).
* CONSTANTS[37] is speed_d in component L_type_Ca_channel_d_gate (dimensionless).
* ALGEBRAIC[18] is alpha_f in component L_type_Ca_channel_f_gate (per_second).
* ALGEBRAIC[25] is beta_f in component L_type_Ca_channel_f_gate (per_second).
* CONSTANTS[38] is speed_f in component L_type_Ca_channel_f_gate (dimensionless).
* CONSTANTS[39] is delta_f in component L_type_Ca_channel_f_gate (millivolt).
* ALGEBRAIC[6] is E0_f in component L_type_Ca_channel_f_gate (millivolt).
* CONSTANTS[40] is g_bca in component calcium_background_current (microS).
* CONSTANTS[41] is g_to in component transient_outward_current (microS).
* CONSTANTS[42] is g_tos in component transient_outward_current (dimensionless).
* STATES[14] is s in component transient_outward_current_s_gate (dimensionless).
* STATES[15] is r in component transient_outward_current_r_gate (dimensionless).
* ALGEBRAIC[7] is alpha_s in component transient_outward_current_s_gate (per_second).
* ALGEBRAIC[19] is beta_s in component transient_outward_current_s_gate (per_second).
* CONSTANTS[43] is g_KACh in component ACh_dependent_potassium_current (microS).
* CONSTANTS[44] is ACh in component ACh_dependent_potassium_current (millimolar).
* CONSTANTS[45] is K_D in component ACh_dependent_potassium_current (millimolar).
* STATES[16] is x_ACh in component ACh_dependent_potassium_current_xACh_gate (dimensionless).
* CONSTANTS[46] is alpha_ACh in component ACh_dependent_potassium_current_xACh_gate (per_second).
* CONSTANTS[47] is beta_ACh in component ACh_dependent_potassium_current_xACh_gate (per_second).
* CONSTANTS[48] is i_NaK_max in component sodium_potassium_pump (nanoA).
* CONSTANTS[49] is K_mK in component sodium_potassium_pump (millimolar).
* CONSTANTS[50] is K_mNa in component sodium_potassium_pump (millimolar).
* ALGEBRAIC[57] is i_NaCa in component sodium_calcium_exchanger (nanoA).
* CONSTANTS[51] is k_NaCa in component sodium_calcium_exchanger (nanoA).
* CONSTANTS[52] is n_NaCa in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[53] is d_NaCa in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[54] is gamma in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[55] is FRiNaCa in component sodium_calcium_exchanger (dimensionless).
* ALGEBRAIC[59] is i_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* CONSTANTS[85] is K_1 in component sarcoplasmic_reticulum_calcium_pump (dimensionless).
* ALGEBRAIC[58] is K_2 in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[56] is K_cyca in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[57] is K_xcs in component sarcoplasmic_reticulum_calcium_pump (dimensionless).
* CONSTANTS[58] is K_srca in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[59] is alpha_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* CONSTANTS[60] is beta_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* STATES[17] is Ca_up in component intracellular_calcium_concentration (millimolar).
* ALGEBRAIC[60] is i_trans in component calcium_translocation (millimolar_per_second).
* STATES[18] is Ca_rel in component intracellular_calcium_concentration (millimolar).
* ALGEBRAIC[61] is i_rel in component calcium_release (millimolar_per_second).
* ALGEBRAIC[9] is VoltDep in component calcium_release (dimensionless).
* ALGEBRAIC[30] is RegBindSite in component calcium_release (dimensionless).
* ALGEBRAIC[21] is CaiReg in component calcium_release (dimensionless).
* ALGEBRAIC[27] is CadsReg in component calcium_release (dimensionless).
* ALGEBRAIC[32] is ActRate in component calcium_release (per_second).
* ALGEBRAIC[34] is InactRate in component calcium_release (per_second).
* CONSTANTS[61] is K_leak_rate in component calcium_release (per_second).
* CONSTANTS[62] is K_m_rel in component calcium_release (per_second).
* CONSTANTS[63] is K_m_Ca_cyt in component calcium_release (millimolar).
* CONSTANTS[64] is K_m_Ca_ds in component calcium_release (millimolar).
* ALGEBRAIC[38] is PrecFrac in component calcium_release (dimensionless).
* STATES[19] is ActFrac in component calcium_release (dimensionless).
* STATES[20] is ProdFrac in component calcium_release (dimensionless).
* ALGEBRAIC[36] is SpeedRel in component calcium_release (dimensionless).
* CONSTANTS[90] is V_i in component intracellular_calcium_concentration (micrometre3).
* STATES[21] is Ca_Calmod in component intracellular_calcium_concentration (millimolar).
* STATES[22] is Ca_Trop in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[65] is Calmod in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[66] is Trop in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[67] is alpha_Calmod in component intracellular_calcium_concentration (per_millimolar_second).
* CONSTANTS[68] is beta_Calmod in component intracellular_calcium_concentration (per_second).
* CONSTANTS[69] is alpha_Trop in component intracellular_calcium_concentration (per_millimolar_second).
* CONSTANTS[70] is beta_Trop in component intracellular_calcium_concentration (per_second).
* CONSTANTS[71] is radius in component intracellular_calcium_concentration (micrometre).
* CONSTANTS[72] is length in component intracellular_calcium_concentration (micrometre).
* CONSTANTS[84] is V_Cell in component intracellular_calcium_concentration (micrometre3).
* CONSTANTS[88] is V_i_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[73] is V_ds_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[74] is V_rel_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[75] is V_e_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[76] is V_up_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[77] is Kdecay in component intracellular_calcium_concentration (per_second).
* STATES[23] is light_chain in component contraction (dimensionless).
* STATES[24] is cross_bridge in component contraction (dimensionless).
* CONSTANTS[78] is KCont1 in component contraction (per_second).
* ALGEBRAIC[10] is XCont2 in component contraction (dimensionless).
* ALGEBRAIC[22] is XCont1 in component contraction (dimensionless).
* CONSTANTS[79] is KCont2 in component contraction (per_second).
* CONSTANTS[80] is KCont3 in component contraction (per_second).
* CONSTANTS[81] is KCont4 in component contraction (per_second).
* CONSTANTS[82] is sarcomere_length in component contraction (micrometre).
* CONSTANTS[83] is cross_bridge_density in component contraction (per_micrometre).
* CONSTANTS[86] is tension_rest in component contraction (dimensionless).
* CONSTANTS[87] is tension_active in component contraction (dimensionless).
* CONSTANTS[89] is overlap in component contraction (micrometre).
* CONSTANTS[91] is cross_bridge_availability in component contraction (dimensionless).
* ALGEBRAIC[11] is isometric_tension in component contraction (dimensionless).
* RATES[0] is d/dt V in component membrane (millivolt).
* RATES[4] is d/dt xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (dimensionless).
* RATES[5] is d/dt xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (dimensionless).
* RATES[6] is d/dt xs in component slow_delayed_rectifier_potassium_current_xs_gate (dimensionless).
* RATES[7] is d/dt m in component fast_sodium_current_m_gate (dimensionless).
* RATES[8] is d/dt h in component fast_sodium_current_h_gate (dimensionless).
* RATES[10] is d/dt d in component L_type_Ca_channel_d_gate (dimensionless).
* RATES[11] is d/dt f in component L_type_Ca_channel_f_gate (dimensionless).
* RATES[12] is d/dt f2 in component L_type_Ca_channel_f2_gate (dimensionless).
* RATES[13] is d/dt f2ds in component L_type_Ca_channel_f2ds_gate (dimensionless).
* RATES[14] is d/dt s in component transient_outward_current_s_gate (dimensionless).
* RATES[15] is d/dt r in component transient_outward_current_r_gate (dimensionless).
* RATES[16] is d/dt x_ACh in component ACh_dependent_potassium_current_xACh_gate (dimensionless).
* RATES[19] is d/dt ActFrac in component calcium_release (dimensionless).
* RATES[20] is d/dt ProdFrac in component calcium_release (dimensionless).
* RATES[2] is d/dt Na_i in component intracellular_sodium_concentration (millimolar).
* RATES[1] is d/dt K_i in component intracellular_potassium_concentration (millimolar).
* RATES[3] is d/dt Ca_i in component intracellular_calcium_concentration (millimolar).
* RATES[21] is d/dt Ca_Calmod in component intracellular_calcium_concentration (millimolar).
* RATES[22] is d/dt Ca_Trop in component intracellular_calcium_concentration (millimolar).
* RATES[9] is d/dt Ca_ds in component intracellular_calcium_concentration (millimolar).
* RATES[17] is d/dt Ca_up in component intracellular_calcium_concentration (millimolar).
* RATES[18] is d/dt Ca_rel in component intracellular_calcium_concentration (millimolar).
* RATES[23] is d/dt light_chain in component contraction (dimensionless).
* RATES[24] is d/dt cross_bridge in component contraction (dimensionless).
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
STATES[0] = -92.849333;
CONSTANTS[0] = 8314.472;
CONSTANTS[1] = 310;
CONSTANTS[2] = 96485.3415;
CONSTANTS[3] = 9.5e-5;
CONSTANTS[4] = 0.1;
CONSTANTS[5] = 1000;
CONSTANTS[6] = 0.5;
CONSTANTS[7] = 0.003;
CONSTANTS[8] = -3;
CONSTANTS[9] = 0.03;
CONSTANTS[10] = 4;
CONSTANTS[11] = 140;
STATES[1] = 136.5644281;
STATES[2] = 7.3321223;
CONSTANTS[12] = 2;
STATES[3] = 1.4e-5;
CONSTANTS[13] = 10;
CONSTANTS[14] = 0.5;
CONSTANTS[15] = 10;
CONSTANTS[16] = 1.25;
CONSTANTS[17] = 0.0021;
CONSTANTS[18] = 0.0013;
STATES[4] = 1.03e-5;
STATES[5] = 2e-7;
CONSTANTS[19] = 0.0026;
STATES[6] = 0.001302;
CONSTANTS[20] = 0;
CONSTANTS[21] = 0.1;
CONSTANTS[22] = 0;
CONSTANTS[23] = 0;
CONSTANTS[24] = 20;
CONSTANTS[25] = 2.5;
STATES[7] = 0.0016203;
STATES[8] = 0.9944036;
CONSTANTS[26] = 1e-5;
CONSTANTS[27] = 0;
CONSTANTS[28] = 0.004;
CONSTANTS[29] = 0.0006;
CONSTANTS[30] = 0.1;
CONSTANTS[31] = 0.002;
CONSTANTS[32] = 0.01;
STATES[9] = 1.88e-5;
STATES[10] = 0;
STATES[11] = 1;
STATES[12] = 0.9349197;
STATES[13] = 0.9651958;
CONSTANTS[33] = 100000;
CONSTANTS[34] = 0.001;
CONSTANTS[35] = 20;
CONSTANTS[36] = 1;
CONSTANTS[37] = 3;
CONSTANTS[38] = 0.3;
CONSTANTS[39] = 0.0001;
CONSTANTS[40] = 0.00025;
CONSTANTS[41] = 0.005;
CONSTANTS[42] = 0;
STATES[14] = 0.9948645;
STATES[15] = 0;
CONSTANTS[43] = 0;
CONSTANTS[44] = 5;
CONSTANTS[45] = 0.00013;
STATES[16] = 0;
CONSTANTS[46] = 0.5;
CONSTANTS[47] = 0.5;
CONSTANTS[48] = 0.7;
CONSTANTS[49] = 1;
CONSTANTS[50] = 40;
CONSTANTS[51] = 0.0005;
CONSTANTS[52] = 3;
CONSTANTS[53] = 0;
CONSTANTS[54] = 0.5;
CONSTANTS[55] = 0.001;
CONSTANTS[56] = 0.0003;
CONSTANTS[57] = 0.4;
CONSTANTS[58] = 0.5;
CONSTANTS[59] = 0.4;
CONSTANTS[60] = 0.03;
STATES[17] = 0.4531889;
STATES[18] = 0.4481927;
CONSTANTS[61] = 0.05;
CONSTANTS[62] = 250;
CONSTANTS[63] = 0.0005;
CONSTANTS[64] = 0.01;
STATES[19] = 0.0042614;
STATES[20] = 0.4068154;
STATES[21] = 0.0005555;
STATES[22] = 0.0003542;
CONSTANTS[65] = 0.02;
CONSTANTS[66] = 0.05;
CONSTANTS[67] = 100000;
CONSTANTS[68] = 50;
CONSTANTS[69] = 100000;
CONSTANTS[70] = 200;
CONSTANTS[71] = 12;
CONSTANTS[72] = 74;
CONSTANTS[73] = 0.1;
CONSTANTS[74] = 0.1;
CONSTANTS[75] = 0.4;
CONSTANTS[76] = 0.01;
CONSTANTS[77] = 10;
STATES[23] = 3.32e-5;
STATES[24] = 8.09e-5;
CONSTANTS[78] = 12000;
CONSTANTS[79] = 100;
CONSTANTS[80] = 60;
CONSTANTS[81] = 25;
CONSTANTS[82] = 2;
CONSTANTS[83] = 0.05;
CONSTANTS[84] = ( 3.14159*pow(CONSTANTS[71]/1000.00, 2.00000)*CONSTANTS[72])/1000.00;
CONSTANTS[85] = ( CONSTANTS[56]*CONSTANTS[57])/CONSTANTS[58];
CONSTANTS[86] = 0.000200000*exp( 2.00000*CONSTANTS[82]);
CONSTANTS[87] = (CONSTANTS[82]>1.00000 ? 1.00000 - exp( - 3.00000*(CONSTANTS[82] - 1.00000)) : 0.00000);
CONSTANTS[88] = ((1.00000 - CONSTANTS[75]) - CONSTANTS[76]) - CONSTANTS[74];
CONSTANTS[89] = (CONSTANTS[82]>2.00000 ? 1.00000 - 0.625000*(CONSTANTS[82] - 2.00000) : 1.00000);
CONSTANTS[90] = CONSTANTS[84]*CONSTANTS[88];
CONSTANTS[91] = CONSTANTS[87]*CONSTANTS[89]*CONSTANTS[83];
}
void
computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
RATES[12] = 1.00000 - 1.00000*(STATES[3]/(CONSTANTS[33]+STATES[3])+STATES[12]);
RATES[13] = CONSTANTS[35]*(1.00000 - (STATES[9]/(CONSTANTS[34]+STATES[9])+STATES[13]));
RATES[15] = 333.000*(1.00000/(1.00000+exp(- (STATES[0]+4.00000)/5.00000)) - STATES[15]);
RATES[16] = CONSTANTS[46]*(1.00000 - STATES[16]) - CONSTANTS[47]*STATES[16];
RATES[24] = CONSTANTS[80]*STATES[23]*(1.00000 - STATES[24]) - CONSTANTS[81]*STATES[24];
ALGEBRAIC[0] = 50.0000/(1.00000+exp(- (STATES[0] - 5.00000)/9.00000));
ALGEBRAIC[12] = 0.0500000*exp(- (STATES[0] - 20.0000)/15.0000);
RATES[4] = ALGEBRAIC[0]*(1.00000 - STATES[4]) - ALGEBRAIC[12]*STATES[4];
ALGEBRAIC[1] = 50.0000/(1.00000+exp(- (STATES[0] - 5.00000)/9.00000));
ALGEBRAIC[13] = 0.400000*exp(- pow((STATES[0]+30.0000)/30.0000, 3.00000));
RATES[5] = ALGEBRAIC[1]*(1.00000 - STATES[5]) - ALGEBRAIC[13]*STATES[5];
ALGEBRAIC[2] = 14.0000/(1.00000+exp(- (STATES[0] - 40.0000)/9.00000));
ALGEBRAIC[14] = 1.00000*exp(- STATES[0]/45.0000);
RATES[6] = ALGEBRAIC[2]*(1.00000 - STATES[6]) - ALGEBRAIC[14]*STATES[6];
ALGEBRAIC[4] = 20.0000*exp( - 0.125000*((STATES[0]+75.0000) - CONSTANTS[27]));
ALGEBRAIC[16] = 2000.00/(1.00000+ 320.000*exp( - 0.100000*((STATES[0]+75.0000) - CONSTANTS[27])));
RATES[8] = ALGEBRAIC[4]*(1.00000 - STATES[8]) - ALGEBRAIC[16]*STATES[8];
ALGEBRAIC[7] = 0.0330000*exp(- STATES[0]/17.0000);
ALGEBRAIC[19] = 33.0000/(1.00000+exp( - 0.125000*(STATES[0]+10.0000)));
RATES[14] = ALGEBRAIC[7]*(1.00000 - STATES[14]) - ALGEBRAIC[19]*STATES[14];
ALGEBRAIC[10] = STATES[21]/CONSTANTS[65];
ALGEBRAIC[22] = STATES[22]/CONSTANTS[66];
RATES[23] = CONSTANTS[78]*pow(ALGEBRAIC[22], 2.00000)*ALGEBRAIC[10]*(1.00000 - STATES[23]) - CONSTANTS[79]*STATES[23];
ALGEBRAIC[3] = STATES[0]+41.0000;
ALGEBRAIC[15] = (fabs(ALGEBRAIC[3])<CONSTANTS[26] ? 2000.00 : ( 200.000*ALGEBRAIC[3])/(1.00000 - exp( - 0.100000*ALGEBRAIC[3])));
ALGEBRAIC[23] = 8000.00*exp( - 0.0560000*(STATES[0]+66.0000));
RATES[7] = ALGEBRAIC[15]*(1.00000 - STATES[7]) - ALGEBRAIC[23]*STATES[7];
ALGEBRAIC[5] = (STATES[0]+24.0000) - 5.00000;
ALGEBRAIC[17] = (fabs(ALGEBRAIC[5])<0.000100000 ? 120.000 : ( 30.0000*ALGEBRAIC[5])/(1.00000 - exp(- ALGEBRAIC[5]/4.00000)));
ALGEBRAIC[24] = (fabs(ALGEBRAIC[5])<0.000100000 ? 120.000 : ( 12.0000*ALGEBRAIC[5])/(exp(ALGEBRAIC[5]/10.0000) - 1.00000));
RATES[10] = CONSTANTS[37]*( ALGEBRAIC[17]*(1.00000 - STATES[10]) - ALGEBRAIC[24]*STATES[10]);
ALGEBRAIC[6] = STATES[0]+34.0000;
ALGEBRAIC[18] = (fabs(ALGEBRAIC[6])<CONSTANTS[39] ? 25.0000 : ( 6.25000*ALGEBRAIC[6])/(exp(ALGEBRAIC[6]/4.00000) - 1.00000));
ALGEBRAIC[25] = 12.0000/(1.00000+exp(( - 1.00000*(STATES[0]+34.0000))/4.00000));
RATES[11] = CONSTANTS[38]*( ALGEBRAIC[18]*(1.00000 - STATES[11]) - ALGEBRAIC[25]*STATES[11]);
ALGEBRAIC[21] = STATES[3]/(STATES[3]+CONSTANTS[63]);
ALGEBRAIC[27] = STATES[9]/(STATES[9]+CONSTANTS[64]);
ALGEBRAIC[30] = ALGEBRAIC[21]+ (1.00000 - ALGEBRAIC[21])*ALGEBRAIC[27];
ALGEBRAIC[34] = 60.0000+ 500.000*pow(ALGEBRAIC[30], 2.00000);
ALGEBRAIC[36] = (STATES[0]<- 50.0000 ? 5.00000 : 1.00000);
RATES[20] = STATES[19]*ALGEBRAIC[36]*ALGEBRAIC[34] - ALGEBRAIC[36]*1.00000*STATES[20];
ALGEBRAIC[9] = exp( 0.0800000*(STATES[0] - 40.0000));
ALGEBRAIC[32] = 0.00000*ALGEBRAIC[9]+ 500.000*pow(ALGEBRAIC[30], 2.00000);
ALGEBRAIC[38] = (1.00000 - STATES[19]) - STATES[20];
RATES[19] = ALGEBRAIC[38]*ALGEBRAIC[36]*ALGEBRAIC[32] - STATES[19]*ALGEBRAIC[36]*ALGEBRAIC[34];
ALGEBRAIC[47] = ((( CONSTANTS[36]*4.00000*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[3]*exp(( 100.000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[12]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1])));
RATES[9] = ( - 1.00000*ALGEBRAIC[47])/( 2.00000*1.00000*CONSTANTS[73]*CONSTANTS[90]*CONSTANTS[2]) - STATES[9]*CONSTANTS[77];
ALGEBRAIC[26] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[10]/STATES[1]);
ALGEBRAIC[35] = ( (( CONSTANTS[14]*CONSTANTS[10])/(CONSTANTS[10]+CONSTANTS[13]))*(STATES[0] - ALGEBRAIC[26]))/(1.00000+exp(( ((STATES[0] - ALGEBRAIC[26]) - CONSTANTS[15])*CONSTANTS[2]*CONSTANTS[16])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[52] = CONSTANTS[41]*(CONSTANTS[42]+ STATES[14]*(1.00000 - CONSTANTS[42]))*STATES[15]*(STATES[0] - ALGEBRAIC[26]);
ALGEBRAIC[37] = (( ( CONSTANTS[17]*STATES[4]+ CONSTANTS[18]*STATES[5])*1.00000)/(1.00000+exp((STATES[0]+9.00000)/22.4000)))*(STATES[0] - ALGEBRAIC[26]);
ALGEBRAIC[29] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log((CONSTANTS[10]+ CONSTANTS[9]*CONSTANTS[11])/(STATES[1]+ CONSTANTS[9]*STATES[2]));
ALGEBRAIC[39] = CONSTANTS[19]*pow(STATES[6], 2.00000)*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[45] = ((( (1.00000 - CONSTANTS[36])*CONSTANTS[31]*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[1]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[10]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[48] = ((( CONSTANTS[36]*CONSTANTS[31]*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[1]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[10]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[54] = ( (( CONSTANTS[48]*CONSTANTS[10])/(CONSTANTS[49]+CONSTANTS[10]))*STATES[2])/(CONSTANTS[50]+STATES[2]);
RATES[1] = (- 1.00000/( 1.00000*CONSTANTS[90]*CONSTANTS[2]))*((ALGEBRAIC[35]+ALGEBRAIC[37]+ALGEBRAIC[39]+ALGEBRAIC[45]+ALGEBRAIC[48]+ALGEBRAIC[52]) - 2.00000*ALGEBRAIC[54]);
ALGEBRAIC[33] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log((CONSTANTS[11]+ 0.120000*CONSTANTS[10])/(STATES[2]+ 0.120000*STATES[1]));
ALGEBRAIC[41] = CONSTANTS[25]*pow(STATES[7], 3.00000)*STATES[8]*(STATES[0] - ALGEBRAIC[33]);
ALGEBRAIC[20] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[11]/STATES[2]);
ALGEBRAIC[43] = CONSTANTS[29]*(STATES[0] - ALGEBRAIC[20]);
ALGEBRAIC[42] = (( CONSTANTS[28]*1.00000)/(1.00000+exp(- (STATES[0]+52.0000)/8.00000)))*(STATES[0] - ALGEBRAIC[20]);
ALGEBRAIC[46] = ((( (1.00000 - CONSTANTS[36])*CONSTANTS[32]*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[2]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[11]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[49] = ((( CONSTANTS[36]*CONSTANTS[32]*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[2]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[11]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[55] = ( (1.00000 - CONSTANTS[55])*CONSTANTS[51]*( exp(( CONSTANTS[54]*(CONSTANTS[52] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(STATES[2], CONSTANTS[52])*CONSTANTS[12] - exp(( (CONSTANTS[54] - 1.00000)*(CONSTANTS[52] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(CONSTANTS[11], CONSTANTS[52])*STATES[3]))/( (1.00000+ CONSTANTS[53]*( STATES[3]*pow(CONSTANTS[11], CONSTANTS[52])+ CONSTANTS[12]*pow(STATES[2], CONSTANTS[52])))*(1.00000+STATES[3]/0.00690000));
RATES[2] = (- 1.00000/( 1.00000*CONSTANTS[90]*CONSTANTS[2]))*(ALGEBRAIC[41]+ALGEBRAIC[42]+ALGEBRAIC[43]+ 3.00000*ALGEBRAIC[54]+ 3.00000*ALGEBRAIC[55]+ALGEBRAIC[46]+ALGEBRAIC[49]);
ALGEBRAIC[40] = ( CONSTANTS[20]*(STATES[0]+80.0000))/(1.00000+pow(CONSTANTS[22]/CONSTANTS[21], 2.00000));
ALGEBRAIC[53] = ( CONSTANTS[43]*(CONSTANTS[10]/(CONSTANTS[10]+CONSTANTS[13]))*STATES[16]*(1.00000/(1.00000+pow(CONSTANTS[45]/CONSTANTS[44], 2.00000)))*(STATES[0] - ALGEBRAIC[26]))/(1.00000+exp(( 2.00000*CONSTANTS[2]*(STATES[0] - (ALGEBRAIC[26]+10.0000)))/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[56] = ( CONSTANTS[55]*CONSTANTS[51]*( exp(( CONSTANTS[54]*(CONSTANTS[52] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(STATES[2], CONSTANTS[52])*CONSTANTS[12] - exp(( (CONSTANTS[54] - 1.00000)*(CONSTANTS[52] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(CONSTANTS[11], CONSTANTS[52])*STATES[9]))/( (1.00000+ CONSTANTS[53]*( STATES[9]*pow(CONSTANTS[11], CONSTANTS[52])+ CONSTANTS[12]*pow(STATES[2], CONSTANTS[52])))*(1.00000+STATES[9]/0.00690000));
ALGEBRAIC[44] = ((( (1.00000 - CONSTANTS[36])*4.00000*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[3]*exp(( 100.000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[12]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[31] = (( 0.500000*CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[12]/STATES[3]);
ALGEBRAIC[51] = CONSTANTS[40]*(STATES[0] - ALGEBRAIC[31]);
ALGEBRAIC[8] = (VOI>=CONSTANTS[4]&&VOI<=CONSTANTS[5]&&(VOI - CONSTANTS[4]) - floor((VOI - CONSTANTS[4])/CONSTANTS[6])*CONSTANTS[6]<=CONSTANTS[7] ? CONSTANTS[8] : 0.00000);
RATES[0] = (- 1.00000/CONSTANTS[3])*(ALGEBRAIC[8]+ALGEBRAIC[35]+ALGEBRAIC[52]+ALGEBRAIC[37]+ALGEBRAIC[39]+ALGEBRAIC[40]+ALGEBRAIC[53]+ALGEBRAIC[54]+ALGEBRAIC[41]+ALGEBRAIC[43]+ALGEBRAIC[42]+ALGEBRAIC[46]+ALGEBRAIC[49]+ALGEBRAIC[55]+ALGEBRAIC[56]+ALGEBRAIC[44]+ALGEBRAIC[47]+ALGEBRAIC[45]+ALGEBRAIC[48]+ALGEBRAIC[51]);
ALGEBRAIC[58] = STATES[3]+ STATES[17]*CONSTANTS[85]+ CONSTANTS[56]*CONSTANTS[57]+CONSTANTS[56];
ALGEBRAIC[59] = (STATES[3]/ALGEBRAIC[58])*CONSTANTS[59] - (( STATES[17]*CONSTANTS[85])/ALGEBRAIC[58])*CONSTANTS[60];
ALGEBRAIC[60] = 50.0000*(STATES[17] - STATES[18]);
RATES[17] = (CONSTANTS[88]/CONSTANTS[76])*ALGEBRAIC[59] - ALGEBRAIC[60];
RATES[21] = CONSTANTS[67]*STATES[3]*(CONSTANTS[65] - STATES[21]) - CONSTANTS[68]*STATES[21];
ALGEBRAIC[61] = ( pow(STATES[19]/(STATES[19]+0.250000), 2.00000)*CONSTANTS[62]+CONSTANTS[61])*STATES[18];
RATES[18] = (CONSTANTS[76]/CONSTANTS[74])*ALGEBRAIC[60] - ALGEBRAIC[61];
RATES[22] = CONSTANTS[69]*STATES[3]*(CONSTANTS[66] - STATES[22]) - CONSTANTS[70]*STATES[22];
RATES[3] = ((( (- 1.00000/( 2.00000*1.00000*CONSTANTS[90]*CONSTANTS[2]))*(((ALGEBRAIC[44]+ALGEBRAIC[51]) - 2.00000*ALGEBRAIC[55]) - 2.00000*ALGEBRAIC[56])+ STATES[9]*CONSTANTS[73]*CONSTANTS[77]+( ALGEBRAIC[61]*CONSTANTS[74])/CONSTANTS[88]) - RATES[21]) - RATES[22]) - ALGEBRAIC[59];
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = 50.0000/(1.00000+exp(- (STATES[0] - 5.00000)/9.00000));
ALGEBRAIC[12] = 0.0500000*exp(- (STATES[0] - 20.0000)/15.0000);
ALGEBRAIC[1] = 50.0000/(1.00000+exp(- (STATES[0] - 5.00000)/9.00000));
ALGEBRAIC[13] = 0.400000*exp(- pow((STATES[0]+30.0000)/30.0000, 3.00000));
ALGEBRAIC[2] = 14.0000/(1.00000+exp(- (STATES[0] - 40.0000)/9.00000));
ALGEBRAIC[14] = 1.00000*exp(- STATES[0]/45.0000);
ALGEBRAIC[4] = 20.0000*exp( - 0.125000*((STATES[0]+75.0000) - CONSTANTS[27]));
ALGEBRAIC[16] = 2000.00/(1.00000+ 320.000*exp( - 0.100000*((STATES[0]+75.0000) - CONSTANTS[27])));
ALGEBRAIC[7] = 0.0330000*exp(- STATES[0]/17.0000);
ALGEBRAIC[19] = 33.0000/(1.00000+exp( - 0.125000*(STATES[0]+10.0000)));
ALGEBRAIC[10] = STATES[21]/CONSTANTS[65];
ALGEBRAIC[22] = STATES[22]/CONSTANTS[66];
ALGEBRAIC[3] = STATES[0]+41.0000;
ALGEBRAIC[15] = (fabs(ALGEBRAIC[3])<CONSTANTS[26] ? 2000.00 : ( 200.000*ALGEBRAIC[3])/(1.00000 - exp( - 0.100000*ALGEBRAIC[3])));
ALGEBRAIC[23] = 8000.00*exp( - 0.0560000*(STATES[0]+66.0000));
ALGEBRAIC[5] = (STATES[0]+24.0000) - 5.00000;
ALGEBRAIC[17] = (fabs(ALGEBRAIC[5])<0.000100000 ? 120.000 : ( 30.0000*ALGEBRAIC[5])/(1.00000 - exp(- ALGEBRAIC[5]/4.00000)));
ALGEBRAIC[24] = (fabs(ALGEBRAIC[5])<0.000100000 ? 120.000 : ( 12.0000*ALGEBRAIC[5])/(exp(ALGEBRAIC[5]/10.0000) - 1.00000));
ALGEBRAIC[6] = STATES[0]+34.0000;
ALGEBRAIC[18] = (fabs(ALGEBRAIC[6])<CONSTANTS[39] ? 25.0000 : ( 6.25000*ALGEBRAIC[6])/(exp(ALGEBRAIC[6]/4.00000) - 1.00000));
ALGEBRAIC[25] = 12.0000/(1.00000+exp(( - 1.00000*(STATES[0]+34.0000))/4.00000));
ALGEBRAIC[21] = STATES[3]/(STATES[3]+CONSTANTS[63]);
ALGEBRAIC[27] = STATES[9]/(STATES[9]+CONSTANTS[64]);
ALGEBRAIC[30] = ALGEBRAIC[21]+ (1.00000 - ALGEBRAIC[21])*ALGEBRAIC[27];
ALGEBRAIC[34] = 60.0000+ 500.000*pow(ALGEBRAIC[30], 2.00000);
ALGEBRAIC[36] = (STATES[0]<- 50.0000 ? 5.00000 : 1.00000);
ALGEBRAIC[9] = exp( 0.0800000*(STATES[0] - 40.0000));
ALGEBRAIC[32] = 0.00000*ALGEBRAIC[9]+ 500.000*pow(ALGEBRAIC[30], 2.00000);
ALGEBRAIC[38] = (1.00000 - STATES[19]) - STATES[20];
ALGEBRAIC[47] = ((( CONSTANTS[36]*4.00000*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[3]*exp(( 100.000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[12]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[26] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[10]/STATES[1]);
ALGEBRAIC[35] = ( (( CONSTANTS[14]*CONSTANTS[10])/(CONSTANTS[10]+CONSTANTS[13]))*(STATES[0] - ALGEBRAIC[26]))/(1.00000+exp(( ((STATES[0] - ALGEBRAIC[26]) - CONSTANTS[15])*CONSTANTS[2]*CONSTANTS[16])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[52] = CONSTANTS[41]*(CONSTANTS[42]+ STATES[14]*(1.00000 - CONSTANTS[42]))*STATES[15]*(STATES[0] - ALGEBRAIC[26]);
ALGEBRAIC[37] = (( ( CONSTANTS[17]*STATES[4]+ CONSTANTS[18]*STATES[5])*1.00000)/(1.00000+exp((STATES[0]+9.00000)/22.4000)))*(STATES[0] - ALGEBRAIC[26]);
ALGEBRAIC[29] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log((CONSTANTS[10]+ CONSTANTS[9]*CONSTANTS[11])/(STATES[1]+ CONSTANTS[9]*STATES[2]));
ALGEBRAIC[39] = CONSTANTS[19]*pow(STATES[6], 2.00000)*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[45] = ((( (1.00000 - CONSTANTS[36])*CONSTANTS[31]*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[1]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[10]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[48] = ((( CONSTANTS[36]*CONSTANTS[31]*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[1]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[10]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[54] = ( (( CONSTANTS[48]*CONSTANTS[10])/(CONSTANTS[49]+CONSTANTS[10]))*STATES[2])/(CONSTANTS[50]+STATES[2]);
ALGEBRAIC[33] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log((CONSTANTS[11]+ 0.120000*CONSTANTS[10])/(STATES[2]+ 0.120000*STATES[1]));
ALGEBRAIC[41] = CONSTANTS[25]*pow(STATES[7], 3.00000)*STATES[8]*(STATES[0] - ALGEBRAIC[33]);
ALGEBRAIC[20] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[11]/STATES[2]);
ALGEBRAIC[43] = CONSTANTS[29]*(STATES[0] - ALGEBRAIC[20]);
ALGEBRAIC[42] = (( CONSTANTS[28]*1.00000)/(1.00000+exp(- (STATES[0]+52.0000)/8.00000)))*(STATES[0] - ALGEBRAIC[20]);
ALGEBRAIC[46] = ((( (1.00000 - CONSTANTS[36])*CONSTANTS[32]*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[2]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[11]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[49] = ((( CONSTANTS[36]*CONSTANTS[32]*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[2]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[11]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[55] = ( (1.00000 - CONSTANTS[55])*CONSTANTS[51]*( exp(( CONSTANTS[54]*(CONSTANTS[52] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(STATES[2], CONSTANTS[52])*CONSTANTS[12] - exp(( (CONSTANTS[54] - 1.00000)*(CONSTANTS[52] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(CONSTANTS[11], CONSTANTS[52])*STATES[3]))/( (1.00000+ CONSTANTS[53]*( STATES[3]*pow(CONSTANTS[11], CONSTANTS[52])+ CONSTANTS[12]*pow(STATES[2], CONSTANTS[52])))*(1.00000+STATES[3]/0.00690000));
ALGEBRAIC[40] = ( CONSTANTS[20]*(STATES[0]+80.0000))/(1.00000+pow(CONSTANTS[22]/CONSTANTS[21], 2.00000));
ALGEBRAIC[53] = ( CONSTANTS[43]*(CONSTANTS[10]/(CONSTANTS[10]+CONSTANTS[13]))*STATES[16]*(1.00000/(1.00000+pow(CONSTANTS[45]/CONSTANTS[44], 2.00000)))*(STATES[0] - ALGEBRAIC[26]))/(1.00000+exp(( 2.00000*CONSTANTS[2]*(STATES[0] - (ALGEBRAIC[26]+10.0000)))/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[56] = ( CONSTANTS[55]*CONSTANTS[51]*( exp(( CONSTANTS[54]*(CONSTANTS[52] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(STATES[2], CONSTANTS[52])*CONSTANTS[12] - exp(( (CONSTANTS[54] - 1.00000)*(CONSTANTS[52] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(CONSTANTS[11], CONSTANTS[52])*STATES[9]))/( (1.00000+ CONSTANTS[53]*( STATES[9]*pow(CONSTANTS[11], CONSTANTS[52])+ CONSTANTS[12]*pow(STATES[2], CONSTANTS[52])))*(1.00000+STATES[9]/0.00690000));
ALGEBRAIC[44] = ((( (1.00000 - CONSTANTS[36])*4.00000*CONSTANTS[30]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[3]*exp(( 100.000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[12]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[31] = (( 0.500000*CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[12]/STATES[3]);
ALGEBRAIC[51] = CONSTANTS[40]*(STATES[0] - ALGEBRAIC[31]);
ALGEBRAIC[8] = (VOI>=CONSTANTS[4]&&VOI<=CONSTANTS[5]&&(VOI - CONSTANTS[4]) - floor((VOI - CONSTANTS[4])/CONSTANTS[6])*CONSTANTS[6]<=CONSTANTS[7] ? CONSTANTS[8] : 0.00000);
ALGEBRAIC[58] = STATES[3]+ STATES[17]*CONSTANTS[85]+ CONSTANTS[56]*CONSTANTS[57]+CONSTANTS[56];
ALGEBRAIC[59] = (STATES[3]/ALGEBRAIC[58])*CONSTANTS[59] - (( STATES[17]*CONSTANTS[85])/ALGEBRAIC[58])*CONSTANTS[60];
ALGEBRAIC[60] = 50.0000*(STATES[17] - STATES[18]);
ALGEBRAIC[61] = ( pow(STATES[19]/(STATES[19]+0.250000), 2.00000)*CONSTANTS[62]+CONSTANTS[61])*STATES[18];
ALGEBRAIC[11] = STATES[24]*CONSTANTS[91]+CONSTANTS[86];
ALGEBRAIC[28] = (( CONSTANTS[23]*STATES[2])/(STATES[2]+CONSTANTS[24]))*(STATES[0] - ALGEBRAIC[26]);
ALGEBRAIC[50] = ALGEBRAIC[44]+ALGEBRAIC[45]+ALGEBRAIC[46]+ALGEBRAIC[47]+ALGEBRAIC[48]+ALGEBRAIC[49];
ALGEBRAIC[57] = ALGEBRAIC[55]+ALGEBRAIC[56];
}