R
R
Neubig
1989-10-31
alpha-2-adrenoreceptor
pharmacology
signal transduction
free receptor
R
C_G_GDP
receptor bound G-protein-GDP
This model has been rebuilt by James Lawson (07/06/07) using differential equations to describe the reactions, instead of reaction elements. This model is known to run in PCEnv, and will likely run in COR as well, though this has not been tested.
Because of the nature of the figures presented in the paper, the output of this model is difficult to compare with the figures.
guanosine diphosphate
GDP
G-protein-GDP
G_GDP
inactivated G-protein
100
8778
28
8786
Rapid kinetics of alpha 2-adrenergic inhibition of adenylate cyclase. Evidence for a distal rate-limiting step
The University of Auckland, Bioengineering Research Group
Richard
Lawson
James
James Lawson
The University of Auckland
The Bioengineering Research Group
Richard
Lawson
James
C_G
receptor bound G-protein
Autumn
A.
Cuellar
2007-06-07T00:00:00+12:00
J
W
Thomsen
GTP
guanosine triphosphate
G-protein activation pathway
G__GTP
activated G-protein
free ligand
L
2007-06-07T10:41:50+12:00
This model has been rebuilt using differential equations to describe the reactions, instead of reaction elements.
Updated metadata to conform to the 16/1/02 CellML Metadata 1.0
Specification.
keyword
adenylate cyclase
This is the CellML description of Thomsen and Neubig's mathematical model of a G-protein activation pathway (1989).
Pi
inorganic phosphate
C_G_GTP
receptor bound G-protein-GTP
C
receptor-ligand complex
j.lawson@auckland.ac.nz
2002-01-21
2574993
Biochemistry
10000
Catherine Lloyd