Search Site
Advanced Search…
Models Home
Exposures
Documentation
Log in
You are here:
Home
/
Exposures
/
Mazhari, Greenstein, Winslow, Marban, Nuss, 2001
/
Molecular Interactions Between Two Long-QT Syndrome Gene Products, HERG and KCNE2, Rationalized by In Vitro and In Silico Analysis
Info
Model Mathematics
Component based math viewer is available
Component: environment
Component: membrane
Component: C1
d
d
time
C1
=
beta_0
C2
-
alpha_0
C1
Component: C2
d
d
time
C2
=
alpha_0
C1
+
Kb
C3
-
beta_0
C2
+
Kf
C2
Component: C3
d
d
time
C3
=
beta_1
O
+
Kf
C2
+
psi
I
-
alpha_i3
C3
+
alpha_1
C3
+
Kb
C3
Component: O
d
d
time
O
=
alpha_1
C3
+
beta_i
I
-
beta_1
O
+
alpha_i
O
Component: I
d
d
time
I
=
alpha_i
O
+
alpha_i3
C3
-
beta_i
I
+
psi
I
Component: reaction_constants
psi
=
beta_1
beta_i
alpha_i3
alpha_1
alpha_i
beta_0
=
0.0227
ⅇ
-0.0431
Vm
alpha_0
=
0.0069
ⅇ
0.0272
Vm
beta_1
=
0.0009
ⅇ
-0.0269
Vm
alpha_1
=
0.0218
ⅇ
0.0262
Vm
beta_i
=
0.0059
ⅇ
-0.0443
Vm
alpha_i
=
0.0622
ⅇ
0.0120
Vm
alpha_i3
=
1.29E-5
ⅇ
2.71E-6
Vm
Source
Derived from workspace
Mazhari, Greenstein, Winslow, Marban, Nuss, 2001
at changeset
0140b8325d41
.
Collaboration
To begin collaborating on this work, please use your git client and issue this command:
Downloads
Download This File
Complete Archive as .tgz
COMBINE Archive (exposure)
Views Available
Documentation
Model Metadata
Mathematics
Generated Code
Cite this model
Source View
Semantic Metadata
Launch with OpenCOR
Tools
CombineArchive Web
Compare...
Export Exposure Metadata
Report a problem with this resource
License
This work is licensed under a
Creative Commons Attribution 3.0 Unported License
.
Navigation
Molecular Interactions Between Two Long-QT Syndrome Gene Products, HERG and KCNE2, Rationalized by In Vitro and In Silico Analysis