van Capelle, Durrer, 1980

Model Status

This is the original unchecked version of the model imported from the previous CellML model repository, 24-Jan-2006.

Model Structure

Often it is not necessary to model the ionic currents of a cell with the accuracy and complexity inherent in the biophysically based models. With a view to investigating phenomena on a larger spatial and temporal scale, several ionic current models have been developed that do not seek to model subcellular processes but only to provide an action potential at a minimal computational cost.

The model created by van Capelle and Durrer (1980) follows the same general form as the FitzHugh-Nagumo model (see The FitzHugh-Nagumo Model, 1961), with a single activation variable and a single recovery variable. It also includes the ability to add more complex parameter representations.

The complete original paper reference is cited below:

Computer simulation of arrhythmias in a network of coupled excitable elements, van Capelle, F.J.L., Durrer, D., 1980, Circ. Res. , 47, 454-466. PubMed ID: 7408126

The raw CellML description of the simplified cardiac myocyte models can be downloaded in various formats as described in . For an example of a more complete documentation for an electrophysiological model, see The Hodgkin-Huxley Squid Axon Model, 1952.