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Modelling Hypertrophic IP3 Transients in the Cardiac Myocyte (Cooling, Hunter, Crampin, 2007)
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Modelling Hypertrophic IP3 Transients in the Cardiac Myocyte (Cooling, Hunter, Crampin, 2007)
Info
Model Mathematics
Component based math viewer is available
Component: all
Cc
=
1
Vc
6.022
e
2
Cp
=
1
Vc
Rpc
Cpc
=
Cc
Cp
d
d
t
P
=
J13
-
J9
+
J8
d
d
t
Pg
=
J9
-
J11
+
J13
d
d
t
Pc
=
J8
+
J12
-
J10
d
d
t
Pcg
=
J10
+
J11
-
J12
J13
=
kf13
Pg
J12
=
kf12
Pcg
kr11
=
kf11
Kd11
J11
=
kf11
Pg
Ca
-
kr11
Pcg
J10
=
kf10
Pc
Gt
-
kr10
Pcg
J8
=
kf8
P
Ca
-
kr8
Pc
J9
=
kf9
P
Gt
-
kr9
Pg
J16
=
kf16
IP3
J14
=
kf14
Pc
PIP2
Km14
Cpc
+
PIP2
J15
=
kf15
Pcg
PIP2
Km15
Cpc
+
PIP2
d
d
t
IP3
=
Cpc
J14
+
J15
-
J16
d
d
t
Gd
=
J7
+
J13
+
J12
-
J2
+
J3
d
d
t
Gt
=
J6
-
J7
+
J9
+
J10
J7
=
kf7
Gt
d
d
t
Ca
=
Cpc
-
1
J8
+
J11
L
=
Ls
1
+
ⅇ
-
80
t
-
ts
-
0.05
if
t
<
ts
+
0.15
∧
t
≥
ts
Ls
if
t
≥
ts
+
0.15
0
otherwise
kr1
=
kf1
Kd1
J1
=
kf1
R
L
-
kr1
Rl
kr2
=
kf2
Kd2
J2
=
kf2
R
Gd
-
kr2
Rg
d
d
t
R
=
-
1
J1
+
J2
J3
=
kf3
Rl
Gd
-
kr3
Rlg
d
d
t
Rl
=
J1
+
J6
-
J3
kr4
=
kf4
Kd4
J4
=
kf4
L
Rg
-
kr4
Rlg
d
d
t
Rg
=
J2
-
J4
J5
=
kf5
Rlg
d
d
t
Rlgp
=
J5
J6
=
kf6
Rlg
d
d
t
Rlg
=
J3
-
J5
+
J4
-
J6
Source
Derived from workspace
Cooling, Hunter, Crampin, 2007
at changeset
ee11a10f3f8f
.
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Creative Commons Attribution 3.0 Unported License
.
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Modelling Hypertrophic IP3 Transients in the Cardiac Myocyte (Cooling, Hunter, Crampin, 2007)